Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

Journal of Leukocyte Biology

Volumn 98, Issue 2, 2015, Pages 249-256

  Petrasek, Jan ^a   Iracheta Vellve, Arvin ^a   Saha, Banishree ^a   Satishchandran, Abhishek ^a   Kodys, Karen ^a   Fitzgerald, Katherine A ^a   Kurt Jones, Evelyn A ^a   Szabo, Gyongyi ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

DAMPs; Inflammasome; Liverinflammation; NLRP3; Sterile inflammatory response

Indexed keywords

ADENOSINE TRIPHOSPHATE; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; URIC ACID; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; CULTURE MEDIUM; LIPOPOLYSACCHARIDE;

ALCOHOL LIVER DISEASE; ALCOHOLIC BEVERAGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINGE DRINKING; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE COURSE; ENZYME ACTIVATION; ENZYME BLOOD LEVEL; FEMALE; HUMAN; IMMUNOCOMPETENT CELL; IN VITRO STUDY; LIVER CELL; LIVER CELL DAMAGE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; URIC ACID BLOOD LEVEL; ADULT; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECTS; GENE DELETION; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LIVER; MALE; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PATHOLOGY; PHARMACOLOGY; PRIMARY CELL CULTURE; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); MUS;

ADENOSINE TRIPHOSPHATE; ADULT; ANIMALS; CARRIER PROTEINS; CELL COMMUNICATION; CULTURE MEDIA, CONDITIONED; FEMALE; GENE DELETION; GENE EXPRESSION; HEPATOCYTES; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; URIC ACID;

EID: 84938404066     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3AB1214-590R     Document Type: Article

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