Association of Pre-miRNA-499 rs3746444 and Pre-miRNA-146a rs2910164 Polymorphisms and Susceptibility to Behcet's Disease

Genetic Testing and Molecular Biomarkers

Volumn 19, Issue 8, 2015, Pages 424-430

  Oner, Tuba ^a   Yenmis, Guven ^a   Tombulturk, Kubra ^a   Cam, Cansu ^a   Kucuk, Ozlem Su ^b   Yakicier, Mustafa Cengiz ^c   Dizman, Didem ^b   Sultuybek, Gonul Kanlgur ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b BEZMIALEM VAKIF UNIVERSITY   (Turkey)

^c ACIBADEM UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 146A; MICRORNA 499; UNCLASSIFIED DRUG; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MIRN146 MICRORNA, HUMAN; MIRN499 MICRORNA, HUMAN; NFKB1 PROTEIN, HUMAN;

ADULT; ALLELE; ARTICLE; BEHCET DISEASE; CASE CONTROL STUDY; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; GENOTYPE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TURK (PEOPLE); BLOOD; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS;

ADULT; BEHCET SYNDROME; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MICRORNAS; NF-KAPPA B P50 SUBUNIT; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84938370300     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2015.0016     Document Type: Article

References (50)

1. Ambros V (2004) The functions of animal microRNAs. Nature 431: 350-355.
2. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
3. Bell ML, Buvoli M, Leinwand LA (2010) Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Mol Cell Biol 30: 1937-1945.
4. Ceribelli A, Nahid MA, Satah M, Chan EKL (2011) Micro-RNAs in rheumatoid arthritis. FEBS Lett 585: 3667-3674.
5. Chen CZ, Li L, Lodish HF, Bartel DP (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science 303: 83-86.
6. Chen HF, Hu TT, Zheng XY, et al. (2013) Association between miR-146a rs2910164 polymorphism and autoimmune diseases susceptibility: A meta-analysis. Gene 521: 259-264.
7. Chu Y-H, Tzeng S-L, Lin C-W, et al. (2012) Impacts of microRNA gene polymorphisms on the susceptibility of environmental factors leading to carcinogenesis in oral cancer. PLoS One 7: e39777.
8. Ciccacci C, Morganti R, Fusco DD, et al. (2014) Common polymorphisms in Mir-146a, MIR128a and MIR27a genes contribute to neuropathy susceptibility in type 2 diabetes. Acta Diabetol 51: 663-671.
9. Cui L, Li Y, Ma G, et al. (2014) A functional polymorphism in the promoter region of microRNA-146a is associated with the risk of Alzheimer disease and the rate of cognitive decline in patients. PLoS One 9: e89019.
10. Dilek K, Özçimen AA, Sarcaog lu H, et al. (2009) Cytokine gene polymorphisms in Behçet's disease and their association with clinical and laboratory findings. Clin Exp Rheumatol 27(Suppl. 53) : S73-S78.
11. Gazouli M, Papaconstantinou I, Stamatis K, et al. (2013) Association study of genetic variants in miRNAs in patients with inflammatory bowel disease: Preliminary results. Dig Dis Sci 58: 2324-2328.
12. Hashemi M, Eskandari-Nasab E, Zakeri Z, et al. (2013) Association of pre-miRNA-146a rs2910164 and pre-miRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis. Mol Med Rep 7: 287-291.
13. Hu Z, Liang J, Wang Z, et al. (2009) Common genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese women. Hum Mut 30: 79-84.
14. Idil A, Gürler A, Boyvat A, et al. (2002) The prevalence of Behçet's disease above the age of 10 years. The results of a pilot study conducted at the Park Primary Health Care Center in Ankara, Turkey. Opthalmic Epidemiol 9: 325-331.
15. International Study Group for Behcet's Disease (1990) Criteria for diagnosis of Behcet's disease. Lancet 335: 1078-1080.
16. Iwai N, Naraba H (2005) Polymorphisms in human pre-miRNAs. Biochem Biophys Res Commun 331: 1439-1444.
17. Jazdzewski K, Liyanarachchi S, Swierniak M, et al. (2009) Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer. Proc Natl Acad Sci U S A 106: 1502-1505.
18. Jazdzewski K, Murray EL, Franssila K, et al. (2008) Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci U S A 105: 7269-7274.
19. Karban AS, Okazaki T, Panhuysen CI, et al. (2004) Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum Mol Genet 13: 35-45.
20. Keating SE, Maloney GM, Moran EM, Bowie AG (2007) IRAK-2 participates in multiple toll-like receptor signaling pathways to NfkappaB via activation of TRAF6 ubiquitination. J Biol Chem 282: 33435-33443.
21. Kirino Y, Bertsias G, Ishigatsubo Y, et al. (2013) Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B 51 and ERAP1. Nat Genet 45: 202-207.
22. Lu L, Tu Y, Liu L, et al. (2014) MicroRNA-499 rs3746444 polymorphism and autoimmune diseases risk: A meta-analysis. Molecular Diagnosis & Therapy 18: 237-242.
23. Luo X, Yang W, Ye DQ, et al. (2011) A functional variant in microRNA-146 promoter modulates its expression and confers disease risk for systemic lupus erythematosus. PLoS Genet 7: e1002128.
24. Ma X, Buscaglia LEB, Barker JR, Li Y (2011) MicroRNAs in NF-KB signaling. J Mol Cell Biol 3: 159-166.
25. Mizuki N, Meguro A, Ota M, et al. (2010) Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci. Nat Genet 42: 703-706.
26. Ohno S, Ohguchi M, Hirose S, et al. (1982) Close association of HLA-Bw51 with Behcet's disease. Arch Ophthalmol 100: 1455-1458.
27. Okubo M, Tahara T, Shibata T, et al. (2011) Association study of common genetic variants in pre-microRNAs in patients with ulcerative colitis. J Clin Immunol 31: 69-73.
28. Pacifico F, Crescenzi E, Mellone S, et al. (2010) Nuclear factor-{kappa}B contributes to anaplastic thyroid carcinomas through upregulation of miR-146a. J Clin Endocrinol Metab 95: 1421-1430.
29. Pedersen IM, Cheng G, Wieland S, et al. (2007) Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 449: 919-922.
30. Remmers EF, Cosan F, Kirino Y, et al. (2010) Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. Nat Genet 42: 698-702.
31. Rodriguez A, Vigorito E, Clare S, et al. (2007) Requirement of bic/microRNA-155 for normal immune function. Science 316: 608-611.
32. Rusca N, Monticelli S (2011) MiR-146a in immunity and disease. Mol Biol Int 2011: 437301.
33. Shao Y, Li J, Cai Y, et al. (2014) The functional polymorphisms of miR-146a are associated with susceptibility to severe sepsis in the Chinese population. Mediators Inflamm 2014: 916202; DOI: 10. 1155/2014/916202.
34. Singh H, Sen R, Baltimore D, Sharp PA (1986) A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature 319: 154-158.
35. Sonkoly E, Wei T, Janson PC, et al. (2007) MicroRNAs: novel regulators involved in the pathogenesis of Psoriasis? PLoS One 2: e610.
36. Sultuybek GK, Yenmis G, Koc A (2014) A general sight about linking PARP-1 and NFKB1 variations to the inflammatory events. Interdiscip J Microinflammation 1: 117 doi: 10. 4172/ ijm. 1000117.
37. Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NFkappaB-dependent induction of microRNAmiR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A 103: 12481-12486.
38. Van Rooij E, Quiat D, Johnson BA, et al. (2009) A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell 17: 662-673.
39. Wei W-J, Wang Y-L, Li D-S, et al. (2013) Association between the rs2910164 polymorphism in pre-Mir-146a sequence and thyroid carcinogenesis. PLoS One 8: e56638.
40. Wilson KD, Hu S, Venkatasubrahmanyam S, et al. (2010) Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499. Circ Cardiovasc Genet 3: 426-435.
41. Xiang Y, Fan S, Cao J, et al. (2012) Association of the micro-RNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population. Mol Biol Rep 39: 7019-7023.
42. Xu B, Feng NH, Li PC, et al. (2010) A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo. Prostate 70: 467-472.
43. Xu T, Zhu Y, Wei Q-K, et al. (2008) A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 29: 2126-2131.
44. Yalcin B, Atakan N, Alli N (2008) The functional role of nuclear factor kappa-kB1-94 ins/del ATTG promotor gene polymorphism in Behçet's disease: An exploratory study. Clin Exp Dermatol 33: 629-633.
45. Yang B, Chen J, Li Y, et al. (2012) Associations of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population. Hum Immunol 73: 101-106.
46. Yazici H, Yurdakul S, Hamuryudan V. (1998) Behçet's syndrome. In: Klippel JH, Dieppe PA (eds) Rheumatology. Mosby, London, pp. 1-6.
47. Yenmis G, Oner T, Cam C, et al. (2015) Association of NFKB1 and NFKBIA polymorphisms in relation to susceptibility of Behçet's Disease. Scand J Immunol 81: 81-86.
48. Zhang M, Xu WD, Wen PF, et al. (2013) Polymorphisms in the tumor necrosis factor gene and susceptibility to Behcet's disease: An updated meta-analysis. Mol Vis 19: 1913-1924.
49. Zhang W, Yi X, Guo S, et al. (2014) A single-nucleotide polymorphism of miR-146a and psoriasis: An association and functional study. J Cell Mol Med 18: 2225-2234.
50. Zhou Q, Hou S, Liang L, et al. (2012) MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behcet's disease and Vogt-Koyanagi-Harada syndrome. Ann Rheum Dis 7: 170-176.