Polymorphisms in the tumor necrosis factor gene and susceptibility to behcet's disease: An updated meta-analysis

Molecular Vision

Volumn 19, Issue , 2013, Pages 1913-1924

  Zhang, Min ^a   Xu, Wang Dong ^a   Wen, Peng Fei ^a   Liang, Yan ^a   Liu, Jie ^a   Pan, Hai Feng ^a   Ye, Dong Qing ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR;

ALLELE; ARTICLE; ASIAN; BEHCET DISEASE; CAUCASIAN; ETHNICITY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC RISK; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SYSTEMATIC REVIEW; TUMOR NECROSIS FACTOR GENE;

BEHCET SYNDROME; CONFIDENCE INTERVALS; GENETIC ASSOCIATION STUDIES; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84884407490     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Sakane T, Takeno M, Suzuki N, Inaba G. Behcet's disease. N Engl J Med 1999; 341:1284-91. [PMID: 10528040].
2. Evereklioglu C. Current concepts in the etiology and treatment of Behcet disease. Surv Ophthalmol 2005; 50:297-350. [PMID: 15967189].
3. Matsuo T, Itami M, Nakagawa H. The incidence and pathology of conjunctival ulceration in Behcet's syndrome. Br J Ophthalmol 2002; 86:140-3. [PMID: 11815335].
4. Colvard DM, Robertson DM, O'Duffy JD. The ocular manifestations of Behcet's disease. Arch Ophthalmol 1977; 95:1813-7. [PMID: 911254].
5. Zamir E, Bodaghi B, Tugal-Tutkun I, See RF, Charlotte F, Wang RC, Wechsler B, LeHoang P, Anteby I, Rao NA. Conjunctival ulcers in Behcet's disease. Ophthalmology 2003; 110:1137-41. [PMID: 12799237].
6. Atmaca LS. Fundus changes associated with Behçet's disease. Graefes Arch Clin Exp Ophthalmol 1989; 227:340-4. [PMID: 2777102].
7. de Menthon M, Lavalley MP, Maldini C, Guillevin L, Mahr A. HLA-B51/B5 and the risk of Behcet's disease: a systematic review and meta-analysis of case-control genetic association studies. Arthritis Rheum 2009; 61:1287-96. [PMID: 19790126].
8. Busch R, De Riva A, Hadjinicolaou AV, Jiang W, Hou T, Mellins ED. On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes. Expert Rev Mol Med 2012; 14:e15 [PMID: 22805744].
9. Remmers EF, Cosan F, Kirino Y, Ombrello MJ, Abaci N, Satorius C, Le JM, Yang B, Korman BD, Cakiris A, Aglar O, Emrence Z, Azakli H, Ustek D, Tugal-Tutkun I, Akman-Demir G, Chen W, Amos CI, Dizon MB, Kose AA, Azizlerli G, Erer B, Brand OJ, Kaklamani VG, Kaklamanis P, Ben-Chetrit E, Stanford M, Fortune F, Ghabra M, Ollier WE, Cho YH, Bang D, O'Shea J, Wallace GR, Gadina M, Kastner DL, Gül A. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease. Nat Genet 2010; 42:698-702. [PMID: 20622878].
10. Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H. Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci. Nat Genet 2010; 42:703-6. [PMID: 20622879].
11. Geri G, Terrier B, Rosenzwajg M, Wechsler B, Touzot M, Seilhean D, Tran TA, Bodaghi B, Musset L, Soumelis V, Klatzmann D, Cacoub P, Saadoun D. Critical role of IL-21 in modulating T(H)17 and regulatory T cells in Behcet disease. J Allergy Clin Immunol 2011; 128:655-64. [PMID: 21724243].
12. Sugita S, Kawazoe Y, Imai A, Kawaguchi T, Horie S, Keino H, Takahashi M, Mochizuki M. Role of IL-22- and TNF-α-Producing Th22 Cells in Uveitis Patients with Behcet's Disease. J Immunol 2013; 190:5799-808. [PMID: 23630362].
13. Hirohata T, Kuratsune M, Nomura A, Jimi S. Prevalence of Behcet's syndrome in Hawaii:with particular reference to the comparison of the Japanese in Hawaii and Japan. Hawaii Med J 1975; 34:244-6. [PMID: 1165185].
14. Zouboulis CC, Kötter I, Djawari D, Kirch W, Kohl PK, Ochsendorf FR, Keitel W, Stadler R, Wollina U, Proksch E, Söhnchen R, Weber H, Gollnick HP, Hölzle E, Fritz K, Licht T, Orfanos CE. Epidemiological features of Adamantiades-Behcet's disease in Germany and Europe. Yonsei Med J 1997; 38:411-22. [PMID: 9509911].
15. Mizushima Y, Matsuda T, Hoshi K, Ohno S. Induction of Behcet's disease symptoms after dental treatment and streptococcal antigen skin test. J Rheumatol 1988; 15:1029-30. [PMID: 3418627].
16. Tojo M, Zheng X, Yanagihori H, Oyama N, Takahashi K, Nakamura K, Kaneko F. Detection of herpes virus genomes in skin lesions from patients with Behcet's disease and other related inflammatory diseases. Acta Derm Venereol 2003; 83:124-7. [PMID: 12735641].
17. Lehner T. The role of heat shock protein, microbial and autoimmune agents in the aetiology of Behcet's disease. Int Rev Immunol 1997; 14:21-32. [PMID: 9203024].
18. Pineton de Chambrun M, Wechsler B, Geri G, Cacoub P, Saadoun D. New insights into the pathogenesis of Behcet's disease. Autoimmun Rev 2012; 11:687-98. [PMID: 22197900].
19. Direskeneli H. Behcet's disease: infectious aetiology, new autoantigens, and HLA-B51. Ann Rheum Dis 2001; 60:996-1002. [PMID: 11602462].
20. Beutler B, Cerami A. The biology of cachectin/TNF-A primary mediator of the host response. Annu Rev Immunol 1989; 7:625-55. [PMID: 2540776].
21. Vassalli P. The pathophysiology of tumor necrosis factors. Annu Rev Immunol 1992; 10:411-52. [PMID: 1590993].
22. Sayinalp N, Ozcebe OI, Ozdemir O, Haznedaroǧlu IC, Dündar S, Kirazli S. Cytokines in Behcet's disease. J Rheumatol 1996; 23:321-2. [PMID: 8882039].
23. Akman A, Sallakci N, Coskun M, Bacanli A, Yavuzer U, Alpsoy E, Yegin O. TNF-alpha gene 1031 T/C polymorphism in Turkish patients with Behcet's disease. Br J Dermatol 2006; 155:350-6. [PMID: 16882174].
24. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 1997; 94:3195-9. [PMID: 9096369].
25. Higuchi T, Seki N, Kamizono S, Yamada A, Kimura A, Kato H, Itoh K. Polymorphism of the 5′-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens 1998; 51:605-12. PMID: 9694352 [PMID: 9694352].
26. Kroeger KM, Carville KS, Abraham LJ. The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 1997; 34:391-9. [PMID: 9293772].
27. Mege JL, Dilsen N, Sanguedolce V, Gul A, Bongrand P, Roux H, Ocal L, Inanç M, Capo C. Overproduction of monocyte derived tumor necrosis factor alpha, interleukin (IL) 6, IL-8 and increased neutrophil superoxide generation in Behcet's disease. A comparative study with familial Mediterranean fever and healthy subjects. J Rheumatol 1993; 20:1544-9. [PMID: 8164212].
28. Yamashita N, Kaneoka H, Kaneko S, Takeno M, Oneda K, Koizumi H, Kogure M, Inaba G, Sakane T. Role of gammadelta T lymphocytes in the development of Behcet's disease. Clin Exp Immunol 1997; 107:241-7. [PMID: 9030859].
29. Robertson LP, Hickling P. Treatment of recalcitrant orogenital ulceration of Behcet's syndrome with infliximab. Rheumatology (Oxford) 2001; 40:473-4. [PMID: 11312390].
30. Sfikakis PP, Theodossiadis PG, Katsiari CG, Kaklamanis P, Markomichelakis NN. Effect of infliximab on sight-threatening panuveitis in Behcet's disease. Lancet 2001; 358:295-6. [PMID: 11498218].
31. Iwata S, Saito K, Yamaoka K, Tsujimura S, Nawata M, Suzuki K, Tanaka Y. Effects of anti-TNF-alpha antibody infliximab in refractory entero-Behcet's disease. Rheumatology (Oxford) 2009; 48:1012-3. [PMID: 19465589].
32. Complete sequence and gene map of a human major histocompatibility complex, The MHC sequencing consortium. Nature 1999; 401:921-3. [PMID: 10553908].
33. Lee EB, Kim JY, Lee YJ, Park MH, Song YW. TNF and TNF receptor polymorphisms in Korean Behcet's disease patients. Hum Immunol 2003; 64:614-20. [PMID: 12770792].
34. Duymaz-Tozkir J, Gül A, Uyar FA, Ozbek U, Saruhan-Direskeneli G. Tumour necrosis factor-alpha gene promoter region -308 and -376 G-> A polymorphisms in Behcet's disease. Clin Exp Rheumatol 2003; 21:S15-8. [PMID: 14727453].
35. Ateş A, Kinikli G, Düzgün N, Duman M. Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in Behcet's disease. Rheumatol Int 2006; 26:348-53. [PMID: 15875188].
36. Park K, Kim N, Nam J, Bang D, Lee ES. Association of TNFA promoter region haplotype in Behcet's Disease. J Korean Med Sci 2006; 21:596-601. [PMID: 16891799].
37. Chang HK, Jang WC, Park SB, Nam YH, Lee SS, Park YW, Kim SK. The novel -G646A polymorphism of the TNF alpha promoter is associated with the HLA-B51 allele in Korean patients with Behcet's disease. Scand J Rheumatol 2007; 36:216-21. [PMID: 17657677].
38. Alayli G, Aydin F, Coban AY, Süllü Y, Cantürk F, Bek Y, Durupinar B, Cantürk T. T helper 1 type cytokines polymorphisms: association with susceptibility to Behcet's disease. Clin Rheumatol 2007; 26:1299-305. [PMID: 17211678].
39. Kamoun M, Chelbi H, Houman MH, Lacheb J, Hamzaoui K. Tumor necrosis factor gene polymorphisms in Tunisian patients with Behcet's disease. Hum Immunol 2007; 68:201-5. [PMID: 17349875].
40. Storz K, Löffler J, Koch S, Vonthein R, Zouboulis CC, Fresko I, Yazici H, Kötter I. IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Behcet's disease in patients of German or Turkish origin. Clin Exp Rheumatol 2008; 26:S103-6. [PMID: 19026125].
41. Akman A, Sallakci N, Kacaroglu H, Tosun O, Yavuzer U, Alpsoy E, Yegin O. Relationship between periodontal findings and the TNF-alpha Gene 1031T/C polymorphism in Turkish patients with Behcet's disease. J Eur Acad Dermatol Venereol 2008; 22:950-7. [PMID: 18355201].
42. Arayssi TK, Hamdan AR, Touma Z, Shamseddeen W, Uthman IW, Hourani HB, Farra CG. TNF polymorphisms in Lebanese patients with Behcet's disease. Clin Exp Rheumatol 2008; 26:S130-1. [PMID: 19026135].
43. Dilek K, Ozçimen AA, Saricaoǧlu H, Saba D, Yücel A, Yurtkuran M, Yurtkuran M, Oral HB. Cytokine gene polymorphisms in Behcet's disease and their association with clinical and laboratory findings. Clin Exp Rheumatol 2009; 27:S73-8. [PMID: 19796538].
44. Bonyadi M, Jahanafrooz Z, Esmaeili M, Kolahi S, Khabazi A, Ebrahimi AA, Hajialilo M, Dastgiri S. TNF-alpha gene polymorphisms in Iranian Azeri Turkish patients with Behcet's Disease. Rheumatol Int 2009; 30:285-9. [PMID: 19774383].
45. Ateş O, Dalyan L, Hatemi G, Hamuryudan V, Topal-Sarikaya A. Topal-Sari{dotless}kaya, Analyses of functional IL10 and TNF-α genotypes in Behcet's syndrome. Mol Biol Rep 2010; 37:3637-41. [PMID: 20191386].
46. Amirzargar A, Shahram F, Nikoopour E, Rezaei N, Saeedfar K, Ziaei N, Davatchi F. Proinflammatory cytokine gene polymorphisms in Behcet's disease. Eur Cytokine Netw 2010; 21:292-6. [PMID: 21059493].
47. Radouane A, Oudghiri M, Chakib A, Bennani S, Touitou I, Barat-Houari M. SNPs in the TNF-α gene promoter associated with Behcet's disease in Moroccan patients. Rheumatology (Oxford) 2012; 51:1595-9. [PMID: 22711844].
48. Xu WD, Peng H, Zhou M, Zhang M, Li BZ, Pan HF, Ye DQ. Association of RANTES and MBL gene polymorphisms with systemic lupus erythematosus: a meta-analysis. Mol Biol Rep 2013; 40:941-8. [PMID: 23065234].
49. Touma Z, Farra C, Hamdan A, Shamseddeen W, Uthman I, Hourani H, Arayssi T. TNF polymorphisms in patients with Behcet disease: a meta-analysis. Arch Med Res 2010; 41:142-6. [PMID: 20470944].
50. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21:1539-58. [PMID: 12111919].
51. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315:629-34. [PMID: 9310563].
52. Brennan FM, Maini RN, Feldmann M. TNF alpha-a pivotal role in rheumatoid arthritis? Br J Rheumatol 1992; 31:293-8. [PMID: 1581770].
53. Negoro K, Kinouchi Y, Hiwatashi N, Takahashi S, Takagi S, Satoh J, Shimosegawa T, Toyota T. Crohn's disease is associated with novel polymorphisms in the 5′-flanking region of the tumor necrosis factor gene. Gastroenterology 1999; 117:1062-8. [PMID: 10535868].
54. Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011; 7:33-42. [PMID: 21119608].
55. Kurreeman FA, Padyukov L, Marques RB, Schrodi SJ, Seddighzadeh M, Stoeken-Rijsbergen G, van der Helm-van Mil AH, Allaart CF, Verduyn W, Houwing-Duistermaat J, Alfredsson L, Begovich AB, Klareskog L, Huizinga TW, Toes RE. A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis. PLoS Med 2007; 4:e278 [PMID: 17880261].
56. Kurreeman FA, Goulielmos GN, Alizadeh BZ, Rueda B, Houwing-Duistermaat J, Sanchez E, Bevova M, Radstake TR, Vonk MC, Galanakis E, Ortego N, Verduyn W, Zervou MI, Roep BO, Dema B, Espino L, Urcelay E, Boumpas DT, van den Berg LH, Wijmenga C, Koeleman BP, Huizinga TW, Toes RE, Martin J. AADEA Group; SLEGEN Consortium. The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases. Ann Rheum Dis 2010; 69:696-9. [PMID: 19433411].
57. Zou YF, Feng XL, Pan FM, Su H, Tao JH, Ye DQ. Meta-analysis of TNF-alpha promoter -238A/G polymorphism and SLE susceptibility. Autoimmunity 2010; 43:264-74. [PMID: 20166876].
58. Campbell RD, Trowsdale J. Map of the human MHC. Immunol Today 1993; 14:349-52. [PMID: 8363724].
59. Charron D. HLA, immunogenetics, pharmacogenetics and personalized medicine. Vox Sang 2011; 100:163-6. [PMID: 21175666].