Molecular mechanisms by which a Fucus vesiculosus extract mediates cell cycle inhibition and cell death in pancreatic cancer cells

Marine Drugs

Volumn 13, Issue 7, 2015, Pages 4470-4491

  Geisen, Ulf ^a   Zenthoefer, Marion ^b   Peipp, Matthias ^a   Kerber, Jannik ^a   Plenge, Johannes ^a   Managò, Antonella ^c   Fuhrmann, Markus ^d   Geyer, Roland ^d   Hennig, Steffen ^b   Adam, Dieter ^a   Piker, Levent ^b   Rimbach, Gerald ^e   Kalthoff, Holger ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b CRM Coastal Research and Management   (Germany)

^c UNIVERSITY OF PADOVA   (Italy)

^d NUMARES AG   (Germany)

^e UNIVERSITY OF KIEL   (Germany)

Author keywords

Algae; Autophagy; Cancer; Cell cycle inhibitors; Fucus vesiculosus; Pancreatic; Proliferation

Indexed keywords

3 METHYLADENINE; ALGAL EXTRACT; ALPHA TUBULIN; BAFILOMYCIN; BETA ACTIN; CASPASE; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 20; CELL CYCLE PROTEIN 25; CELL CYCLE PROTEIN 45; CELL CYCLE PROTEIN 7; CHLOROQUINE; CYCLIN D3; CYCLIN DEPENDENT KINASE INHIBITOR 1C; CYCLIN E; CYCLINE; FLUOROURACIL; FUCUS VESICULOSUS EXTRACT; GEMCITABINE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN P15; PROTEIN P16; PROTEIN P21; PROTEIN P27; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; PLANT EXTRACT;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHAGY; CELL CYCLE ARREST; CELL DEATH; CELL DIFFERENTIATION; CELL DIVISION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME DEGRADATION; ERYTHROCYTE; FRACTIONATION; G2 PHASE CELL CYCLE CHECKPOINT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VITRO STUDY; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; PANCREAS CANCER; PANCREATIC CANCER CELL LINE; UPREGULATION; CELL CYCLE; CHEMISTRY; DRUG EFFECTS; FUCUS; PANCREATIC NEOPLASMS; PHYSIOLOGY; TUMOR CELL LINE;

ALGAE; FUCUS VESICULOSUS;

AUTOPHAGY; CASPASES; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; FUCUS; HUMANS; PANCREATIC NEOPLASMS; PLANT EXTRACTS;

EID: 84938248577     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13074470     Document Type: Article

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