A comprehensive study of the association between drug hepatotoxicity and daily dose, liver metabolism, and lipophilicity using 975 oral medications

Oncotarget

Volumn 6, Issue 19, 2015, Pages 17031-17038

  Weng, Zuquan ^a   Wang, Kejian ^a   Li, Haibo ^b   Shi, Qiang ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Department of Obstetrics and Gynecology   (China)

Author keywords

Dose; Hepatotoxicity; Lipophilicity; Metabolism; Oral

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; PRESCRIPTION DRUG; RAMIPRIL;

ACUTE LIVER FAILURE; ARTICLE; DOSE RESPONSE; DRUG METABOLISM; DRUG USE; HEPATITIS; HEPATOMEGALY; HUMAN; JAUNDICE; LIPOPHILICITY; LIVER METABOLISM; LIVER TOXICITY; LIVER TRANSPLANTATION; PREDICTION; RISK FACTOR; SIDE EFFECT; DRUG EFFECTS; LIVER; ORAL DRUG ADMINISTRATION; TOXIC HEPATITIS;

ADMINISTRATION, ORAL; CHEMICAL AND DRUG INDUCED LIVER INJURY; HUMANS; LIVER; PRESCRIPTION DRUGS;

EID: 84938222597     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4400     Document Type: Article

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