Application of high-resolution mass spectrometry to measure low abundance isotope enrichment in individual muscle proteins

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 14, 2015, Pages 4045-4052

  Hines, Kelly M ^a   Ford, G Charles ^a   Klaus, Katherine A ^a   Irving, Brian A ^a   Ford, Beverly L ^a   Johnson, Kenneth L ^a   Lanza, Ian R ^a   Nair, K Sreekumaran ^a  

^a MAYO CLINIC   (United States)

Author keywords

Fractional synthesis rate; High resolution; LC MS MS; Mass spectrometry; Muscle protein; Protein synthesis; Stable isotope

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; ELECTROPHORESIS; IMPURITIES; ISOTOPES; MASS SPECTROMETERS; MASS SPECTROMETRY; MUSCLE; SPECTROMETERS; SPECTROMETRY;

FRACTIONAL SYNTHESIS RATES; HIGH RESOLUTION; LC-MS/MS; MUSCLE PROTEINS; PROTEIN SYNTHESIS; STABLE ISOTOPES;

PROTEINS;

MUSCLE PROTEIN;

ADULT; AGED; CHEMISTRY; DEVICES; FEMALE; HUMAN; MALE; MASS SPECTROMETRY; MIDDLE AGED; PROCEDURES; SKELETAL MUSCLE;

ADULT; AGED; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE, SKELETAL;

EID: 84938090746     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-8641-2     Document Type: Article

References (25)

1. Halliday D and Ford GC (1988) Stable isotopes in clinical investigation. In: Mass spectrometry. Walter de Gruyter, Inc., Hawthorne, NY
2. Halliday D, Read WW (1981) Proc Nutr Soc 40:321-334
3. Nair KS, Halliday D, Griggs RC (1988) Am J Physiol Endocrinol Metab 254:E208-E213
4. Matthews DE, Hayes JM (1978) Anal Chem 50:1465-1473
5. Balagopal P, Ljungqvist O, Ford GC, Nair KS (1996) Skeletal muscle myosin heavy chain synthesis rate in healthy humans. J Invest Med 44(3):273A
6. Yarasheski KE, Smith K, Rennie MJ, Bier DM (1992) Biol Mass Spec 21:486-490
7. Rennie MJ, Edwards RHT, Halliday D, Matthews DE, Wolman SL, Millward DJ (1982) Clin Sci 63:519-523
8. Rennie MJ, Smith K, Watt PW (1994) Am J Physiol Endocrinol Metab 266:E298-E307
9. Rooyackers OE, Balagopal P, Nair KS (1997) Muscle Nerve 5(suppl):S93-S96
10. Balagopal P, Rooyackers OE, Adey DB, Ades PA, Nair KS (1997) Am J Physiol Endocrinol Metab 273:E790-E800
11. Toth MJ, Matthews DE, Tracy RP, Previs MJ (2005) Am J Physiol Endocrinol Metab 288:E883-E891
12. Kumar V, Atherton P, Smith K, Rennie MJ (2009) J Appl Physiol (1985) 106:2026-2039
13. Kumar V, Atherton PJ, Selby A, Rankin D, Williams J, Smith K, Hiscock N, Rennie MJ (2012) J Gerontol A Biol Sci Med Sci 67:1170-1177
14. Patterson BW, Zhang X-J, Chen YP, Klein S, Wolfe RR (1997) Metab: Clin Exp 46:943-948
15. Calder AG, Anderson SE, Grant I, McNurlan MA, Garlick PJ (1992) Rapid Commun Mass Spec 6:421-424
16. Jaleel A, Short KR, Asmann YW, Klaus KA, Morse DM, Ford GC, Nair KS (2008) Am J Physiol Endocrinol Metab 295:E1255-E1268
17. Zhang XJ, Chinkes DL, Wolfe RR (2002) Am J Physiol Endocrinol Metab 283:E753-E764
18. Zabielski P, Ford GC, Persson XM, Jaleel A, Dewey JD, Nair KS (2013) J Mass Spectrom 48:269-275
19. Short KR, Meek SE, Moller N, Ekberg K, Nair KS (1999) Am J Physiol Endocrinol Metab 276:E1194-E1200
20. Nair KS, Ford GC, Ekberg K, Fernqvist-Forbes E, Wahren J (1995) J Clin Invest 95:2926-2937
21. Edwards RH (1971) Lancet 2:593-595
22. Rooyackers OE, Adey DB, Ades PA, Nair KS (1996) Proc Natl Acad Sci USA 93:15364-15369
23. Jaleel A, Henderson GC, Madden BJ, Klaus KA, Morse DM, Gopala S, Nair KS (2010) Diabetes 59:2366-2374
24. Lanza IR, Zabielski P, Klaus KA, Morse DM, Heppelmann CJ, Bergen HR III, Dasari S, Walrand S, Short KR, Johnson ML, Robinson ML, Schimke JC, Jakaitis DR, Asmann YW, Sun Z, Nair KS (2012) Cell Metab 16:777-788
25. Higashi RM, Fan TW, Lorkiewicz PK, Moseley HN, Lane AN (2014) Methods Mol Biol 1198:147-167