Polymeric Nanovehicle Regulated Spatiotemporal Real-Time Imaging of the Differentiation Dynamics of Transplanted Neural Stem Cells after Traumatic Brain Injury

ACS Nano

Volumn 9, Issue 7, 2015, Pages 6683-6695

  Wang, Zhe ^a   Wang, Yu ^a   Wang, Zhiyong ^b   Zhao, Jun ^c   Gutkind, J Silvio ^b   Srivatsan, Avinash ^a   Zhang, Guofeng ^a   Liao, Hsien Shun ^a   Fu, Xiao ^a   Jin, Albert ^a   Tong, Xiao ^a   Niu, Gang ^a   Chen, Xiaoyuan ^a  

^a NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

differentiation; imaging; nanoparticles; stem cells; traumatic brain injury

Indexed keywords

BRAIN; CELL DEATH; DIFFERENTIATION (CALCULUS); GENE EXPRESSION; GENES; IMAGING TECHNIQUES; NANOPARTICLES; POLYMERS; STEM CELLS;

BICISTRONIC VECTOR; CENTRAL NERVOUS SYSTEMS; CONVENTIONAL METHODS; DIRECTED DIFFERENTIATIONS; EFFECTIVE CONCENTRATION; REGENERATIVE MEDICINE; REPORTER-GENE EXPRESSION; TRAUMATIC BRAIN INJURIES;

NEURONS;

NANOPARTICLE; POLYMER;

ANIMAL; BRAIN INJURY; CELL CULTURE; CHEMISTRY; CYTOLOGY; METABOLISM; MOLECULAR IMAGING; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PATHOLOGY; PROCEDURES; TRANSPLANTATION;

ANIMALS; BRAIN INJURIES; CELLS, CULTURED; MICE; MOLECULAR IMAGING; NANOPARTICLES; NEURAL STEM CELLS; NEUROGENESIS; POLYMERS;

EID: 84938062135     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b00690     Document Type: Article

References (44)

1. Muller, F. J.; Snyder, E. Y.; Loring, J. F. Gene Therapy: Can Neural Stem Cells Deliver? Nat. Rev. Neurosci. 2006, 7, 75-84
2. Martino, G.; Pluchino, S. The Therapeutic Potential of Neural Stem Cells Nat. Rev. Neurosci. 2006, 7, 395-406
3. Hsu, Y. C.; Li, L.; Fuchs, E. Transit-Amplifying Cells Orchestrate Stem Cell Activity and Tissue Regeneration Cell 2014, 157, 935-949
4. Clevers, H.; Loh, K. M.; Nusse, R. Stem Cell Signaling. An Integral Program for Tissue Renewal and Regeneration: Wnt Signaling and Stem Cell Control Science 2014, 346, 1248012
5. Beal, M. F.; Hantraye, P. Novel Therapies In the Search for a Cure for Huntington's Disease Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 3-4
6. Sanberg, P. R. Neural Stem Cells for Parkinson's Disease: To Protect and Repair Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 11869-11870
7. Lindvall, O.; Kokaia, Z.; Martinez-Serrano, A. Stem Cell Therapy for Human Neurodegenerative Disorders-How To Make It Work Nat. Med. 2004, 10 (Suppl.) S42-S50
8. Pluchino, S.; Zanotti, L.; Rossi, B.; Brambilla, E.; Ottoboni, L.; Salani, G.; Martinello, M.; Cattalini, A.; Bergami, A.; Furlan, R. Neurosphere-Derived Multipotent Precursors Promote Neuroprotection by an Immunomodulatory Mechanism Nature 2005, 436, 266-271
9. Lancaster, M. A.; Renner, M.; Martin, C. A.; Wenzel, D.; Bicknell, L. S.; Hurles, M. E.; Homfray, T.; Penninger, J. M.; Jackson, A. P.; Knoblich, J. A. Cerebral Organoids Model Human Brain Development and Microcephaly Nature 2013, 501, 373-379
10. Brito, C.; Simao, D.; Costa, I.; Malpique, R.; Pereira, C. I.; Fernandes, P.; Serra, M.; Schwarz, S. C.; Schwarz, J.; Kremer, E. J. 3D Cultures of Human Neural Progenitor Cells: Dopaminergic Differentiation and Genetic Modification Methods 2012, 56, 452-460
11. Abrous, D. N.; Koehl, M.; Le Moal, M. Adult Neurogenesis: From Precursors to Network and Physiology Physiol. Rev. 2005, 85, 523-569
12. Lie, D. C.; Song, H.; Colamarino, S. A.; Ming, G. L.; Gage, F. H. Neurogenesis in the Adult Brain: New Strategies for Central Nervous System Diseases Annu. Rev. Pharmacol. Toxicol. 2004, 44, 399-421
13. Gross, C. G. Neurogenesis in the Adult Brain: Death of a Dogma Nat. Rev. Neurosci. 2000, 1, 67-73
14. Sanai, N.; Nguyen, T.; Ihrie, R. A.; Mirzadeh, Z.; Tsai, H. H.; Wong, M.; Gupta, N.; Berger, M. S.; Huang, E.; Garcia-Verdugo, J. M. Corridors of Migrating Neurons in the Human Brain and Their Decline during Infancy Nature 2011, 478, 382-386
15. Belmadani, A.; Tran, P. B.; Ren, D.; Miller, R. J. Chemokines Regulate the Migration of Neural Progenitors to Sites of Neuroinflammation J. Neurosci. 2006, 26, 3182-3191
16. Abematsu, M.; Tsujimura, K.; Yamano, M.; Saito, M.; Kohno, K.; Kohyama, J.; Namihira, M.; Komiya, S.; Nakashima, K. Neurons Derived from Transplanted Neural Stem Cells Restore Disrupted Neuronal Circuitry in a Mouse Model of Spinal Cord Injury J. Clin. Invest. 2010, 120, 3255-3266
17. Ziller, M. J.; Edri, R.; Yaffe, Y.; Donaghey, J.; Pop, R.; Mallard, W.; Issner, R.; Gifford, C. A.; Goren, A.; Xing, J. Dissecting Neural Differentiation Regulatory Networks through Epigenetic Footprinting Nature 2015, 19, 355-359
18. Yang, F.; Liu, Y.; Tu, J.; Wan, J.; Zhang, J.; Wu, B.; Chen, S.; Zhou, J.; Mu, Y.; Wang, L. Activated Astrocytes Enhance the Dopaminergic Differentiation of Stem Cells and Promote Brain Repair Through Bfgf Nat. Commun. 2014, 5, 5627
19. Louis, S. A.; Mak, C. K.; Reynolds, B. A. Methods To Culture, Differentiate, and Characterize Neural Stem Cells from the Adult and Embryonic Mouse Central Nervous System Methods Mol. Biol. 2013, 946, 479-506
20. Hu, B. Y.; Zhang, S. C. Directed Differentiation of Neural-Stem Cells and Subtype-Specific Neurons from hESCs Methods Mol. Biol. 2010, 636, 123-137
21. Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Braganca, J.; Malva, J. O.; Ferreira, L.; Bernardino, L. Polymeric Nanoparticles To Control the Differentiation of Neural Stem Cells in the Subventricular Zone of the Brain ACS Nano 2012, 6, 10463-10474
22. Pollard, S. M.; Conti, L.; Sun, Y.; Goffredo, D.; Smith, A. Adherent Neural Stem (NS) Cells from Fetal and Adult Forebrain Cereb. Cortex. 2006, 16 (Suppl. 1) I112-1120
23. Kokovay, E.; Shen, Q.; Temple, S. The Incredible Elastic Brain: How Neural Stem Cells Expand Our Minds Neuron 2008, 60, 420-429
24. Uchida, N.; Chen, K.; Dohse, M.; Hansen, K. D.; Dean, J.; Buser, J. R.; Riddle, A.; Beardsley, D. J.; Wan, Y.; Gong, X. Human Neural Stem Cells Induce Functional Myelination in Mice with Severe Dysmyelination Sci. Transl. Med. 2012, 4, 155ra136
25. Gupta, N.; Henry, R. G.; Strober, J.; Kang, S. M.; Lim, D. A.; Bucci, M.; Caverzasi, E.; Gaetano, L.; Mandelli, M. L.; Ryan, T. Neural Stem Cell Engraftment and Myelination in the Human Brain Sci. Transl. Med. 2012, 4, 155ra137
26. Teng, Y. D.; Benn, S. C.; Kalkanis, S. N.; Shefner, J. M.; Onario, R. C.; Cheng, B.; Lachyankar, M. B.; Marconi, M.; Li, J.; Yu, D. Multimodal Actions of Neural Stem Cells in a Mouse Model of ALS: A Meta-Analysis Sci. Transl. Med. 2012, 4, 165ra164
27. Tonge, P. D.; Andrews, P. W. Retinoic Acid Directs Neuronal Differentiation of Human Pluripotent Stem Cell Lines in a Non-Cell-Autonomous Manner Differentiation 2010, 80, 20-30
28. Okada, Y.; Shimazaki, T.; Sobue, G.; Okano, H. Retinoic-Acid-Concentration-Dependent Acquisition of Neural Cell Identity During in Vitro Differentiation of Mouse Embryonic Stem Cells Dev. Biol. 2004, 275, 124-142
29. Wang, Z.; Zhang, R.; Wang, H. F.; Wang, Y.; Zhao, J.; Wang, F.; Li, W.; Niu, G.; Kiesewetter, D. O.; Chen, X. Bioinspired Nanocomplex for Spatiotemporal Imaging of Sequential Mrna Expression in Differentiating Neural Stem Cells ACS Nano 2014, 8, 12386-12396
30. Chanda, B.; Ditadi, A.; Iscove, N. N.; Keller, G. Retinoic Acid Signaling Is Essential for Embryonic Hematopoietic Stem Cell Development Cell 2013, 155, 215-227
31. Varga, B. V.; Hadinger, N.; Gocza, E.; Dulberg, V.; Demeter, K.; Madarasz, E.; Herberth, B. Generation of Diverse Neuronal Subtypes in Cloned Populations of Stem-like Cells BMC Dev. Biol. 2008, 8, 89
32. Danhier, F.; Ansorena, E.; Silva, J. M.; Coco, R.; Le Breton, A.; Preat, V. PLGA-Based Nanoparticles: An Overview of Biomedical Applications J. Controlled Release 2012, 161, 505-522
33. Wang, Z.; Ho, P. C. A Nanocapsular Combinatorial Sequential Drug Delivery System for Antiangiogenesis and Anticancer Activities Biomaterials 2010, 31, 7115-7123
34. Wang, Z.; Chui, W. K.; Ho, P. C. Nanoparticulate Delivery System Targeted to Tumor Neovasculature for Combined Anticancer and Antiangiogenesis Therapy Pharm. Res. 2011, 28, 585-596
35. Wang, Z.; Niu, G.; Chen, X. Polymeric Materials for Theranostic Applications Pharm. Res. 2014, 31, 1358-1376
36. Gaudin, A.; Yemisci, M.; Eroglu, H.; Lepetre-Mouelhi, S.; Turkoglu, O. F.; Donmez-Demir, B.; Caban, S.; Sargon, M. F.; Garcia-Argote, S. Squalenoyl Adenosine Nanoparticles Provide Neuroprotection after Stroke and Spinal Cord Injury Nat. Nanotechnol. 2014, 9, 1054-1062
37. Stavridis, M. P.; Collins, B. J.; Storey, K. G. Retinoic Acid Orchestrates Fibroblast Growth Factor Signalling To Drive Embryonic Stem Cell Differentiation Development 2010, 137, 881-890
38. Attardo, A.; Calegari, F.; Haubensak, W.; Wilsch-Brauninger, M.; Huttner, W. B. Live Imaging at the Onset of Cortical Neurogenesis Reveals Differential Appearance of the Neuronal Phenotype in Apical versus Basal Progenitor Progeny PLoS One 2008, 3, E2388
39. Griesbach, G. S.; Hovda, D. A.; Molteni, R.; Gomez-Pinilla, F. Alterations in BDNF and Synapsin I within the Occipital Cortex and Hippocampus after Mild Traumatic Brain Injury in the Developing Rat: Reflections of Injury-Induced Neuroplasticity J. Neurotrauma 2002, 19, 803-814
40. Carbajal, K. S.; Schaumburg, C.; Strieter, R.; Kane, J.; Lane, T. E. Migration of Engrafted Neural Stem Cells Is Mediated by CXCL12 Signaling through CXCR4 in a Viral Model of Multiple Sclerosis Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 11068-11073
41. Wang, Z.; Wang, Y.; Gutkind, J. S.; Wang, F.; Lu, J.; Niu, G.; Teng, G.; Chen, X. Engineered Mesenchymal Stem Cells with Enhanced Tropism and Paracrine Secretion of Cytokines and Growth Factors To Treat Traumatic Brain Injury Stem Cells 2015, 33, 456-467
42. Wang, Z.; Chui, W. K.; Ho, P. C. Design of a Multifunctional PLGA Nanoparticulate Drug Delivery System: Evaluation of Its Physicochemical Properties and Anticancer Activity to Malignant Cancer Cells Pharm. Res. 2009, 26, 1162-1171
43. Wang, Z.; Ho, P. C. Self-Assembled Core-Shell Vascular-Targeted Nanocapsules for Temporal Antivasculature and Anticancer Activities Small 2010, 6, 2576-2583
44. Wang, Z.; Zhang, X.; Huang, P.; Zhao, W.; Liu, D.; Nie, L.; Yue, X.; Wang, S.; Ma, Y.; Kiesewetter, D. Dual-Factor Triggered Fluorogenic Nanoprobe for Ultrahigh Contrast and Subdiffraction Fluorescence Imaging Biomaterials 2013, 34, 6194-6201