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Volumn 22, Issue 7, 2015, Pages 344-350

Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; RED FLUORESCENT PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; PHOTOPROTEIN;

EID: 84937978947     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2015.26     Document Type: Article
Times cited : (45)

References (31)
  • 1
    • 73349100697 scopus 로고    scopus 로고
    • The FLARE intraoperative near-infrared fluorescence imaging system: A first-in-human clinical trial in breast cancer sentinel lymph node mapping
    • Troyan SL, Kianzad V, Gibbs-Strauss SL, Gioux S, Matsui A, Oketokoun R et al. The FLARE intraoperative near-infrared fluorescence imaging system: a first-in-human clinical trial in breast cancer sentinel lymph node mapping. Ann Surg Oncol 2009; 16: 2943-2952.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2943-2952
    • Troyan, S.L.1    Kianzad, V.2    Gibbs-Strauss, S.L.3    Gioux, S.4    Matsui, A.5    Oketokoun, R.6
  • 2
    • 33645986455 scopus 로고    scopus 로고
    • Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial
    • Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ et al. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol 2006; 7: 392-401.
    • (2006) Lancet Oncol , vol.7 , pp. 392-401
    • Stummer, W.1    Pichlmeier, U.2    Meinel, T.3    Wiestler, O.D.4    Zanella, F.5    Reulen, H.J.6
  • 3
    • 81855172515 scopus 로고    scopus 로고
    • Glowing tumors make for better detection and resection
    • Bouvet M, Hoffman RM. Glowing tumors make for better detection and resection. Sci Transl Med 2011; 3: 110sf10.
    • (2011) Sci Transl Med , vol.3 , pp. 110sf10
    • Bouvet, M.1    Hoffman, R.M.2
  • 4
    • 43949092126 scopus 로고    scopus 로고
    • Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation
    • McElroy M, Kaushal S, Luiken GA, Talamini MA, Moossa AR, Hoffman RM et al. Imaging of primary and metastatic pancreatic cancer using a fluorophore-conjugated anti-CA19-9 antibody for surgical navigation. World J Surg 2008; 32: 1057-1066.
    • (2008) World J Surg , vol.32 , pp. 1057-1066
    • McElroy, M.1    Kaushal, S.2    Luiken, G.A.3    Talamini, M.A.4    Moossa, A.R.5    Hoffman, R.M.6
  • 5
    • 84861580454 scopus 로고    scopus 로고
    • An LED light source and novel fluorophore combinations improve fluorescence laparoscopic detection of metastatic pancreatic cancer in orthotopic mouse models
    • Metildi CA, Kaushal S, Lee C, Hardamon CR, Snyder CS, Luiken GA et al. An LED light source and novel fluorophore combinations improve fluorescence laparoscopic detection of metastatic pancreatic cancer in orthotopic mouse models. J Am Coll Surg 2012; 214: 997-1007.
    • (2012) J Am Coll Surg , vol.214 , pp. 997-1007
    • Metildi, C.A.1    Kaushal, S.2    Lee, C.3    Hardamon, C.R.4    Snyder, C.S.5    Luiken, G.A.6
  • 6
    • 84862979798 scopus 로고    scopus 로고
    • Fluorescence-guided surgery allows for more complete resection of pancreatic cancer, resulting in longer disease-free survival compared with standard surgery in orthotopic mouse models
    • Metildi CA, Kaushal S, Hardamon CR, Snyder CS, Pu M, Messer KS et al. Fluorescence-guided surgery allows for more complete resection of pancreatic cancer, resulting in longer disease-free survival compared with standard surgery in orthotopic mouse models. J Am Coll Surg 2012; 215: 126-136.
    • (2012) J Am Coll Surg , vol.215 , pp. 126-136
    • Metildi, C.A.1    Kaushal, S.2    Hardamon, C.R.3    Snyder, C.S.4    Pu, M.5    Messer, K.S.6
  • 7
    • 84870677679 scopus 로고    scopus 로고
    • Fluorescence-guided surgery of human colon cancer increases complete resection resulting in cures in an orthotopic nude mouse model
    • Metildi CA, Kaushal S, Snyder CS, Hoffman RM, Bouvet M. Fluorescence-guided surgery of human colon cancer increases complete resection resulting in cures in an orthotopic nude mouse model. J Surg Res 2013; 179: 87-93.
    • (2013) J Surg Res , vol.179 , pp. 87-93
    • Metildi, C.A.1    Kaushal, S.2    Snyder, C.S.3    Hoffman, R.M.4    Bouvet, M.5
  • 8
    • 84874920586 scopus 로고    scopus 로고
    • Fluorescence-guided surgery and fluorescence laporascopy for gastrointestinal cancers in clinically-relevant mouse models
    • Metildi CA, Hoffman RM, Bouvet M. Fluorescence-guided surgery and fluorescence laporascopy for gastrointestinal cancers in clinically-relevant mouse models. Gastroenterol Res Pract 2013; 2013: Article ID 290634.
    • (2013) Gastroenterol Res Pract , vol.2013
    • Metildi, C.A.1    Hoffman, R.M.2    Bouvet, M.3
  • 9
    • 84892793294 scopus 로고    scopus 로고
    • In vivo fluorescence imaging of gastrointestinal stromal tumors using fluorophoreconjugated anti-KIT antibody
    • Metildi CA, Tang CM, Kaushal S, Leonard SY, Magistri P, Tran Cao HS et al. In vivo fluorescence imaging of gastrointestinal stromal tumors using fluorophoreconjugated anti-KIT antibody. Ann Surg Oncol 2013; Suppl 3: 693-700.
    • (2013) Ann Surg Oncol , pp. 693-700
    • Metildi, C.A.1    Tang, C.M.2    Kaushal, S.3    Leonard, S.Y.4    Magistri, P.5    Tran Cao, H.S.6
  • 10
    • 84896085965 scopus 로고    scopus 로고
    • Fluorescenceguided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA), that highlights the tumor, improves surgical resection and increases survival in orthotopic mouse models of human pancreatic cancer
    • Metildi CA, Kaushal S, Pu M, Messer KA, Luiken GA, Moossa AR et al. Fluorescenceguided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA), that highlights the tumor, improves surgical resection and increases survival in orthotopic mouse models of human pancreatic cancer. Ann Surg Oncol 2014; 21: 1405-1411.
    • (2014) Ann Surg Oncol , vol.21 , pp. 1405-1411
    • Metildi, C.A.1    Kaushal, S.2    Pu, M.3    Messer, K.A.4    Luiken, G.A.5    Moossa, A.R.6
  • 11
    • 84897021045 scopus 로고    scopus 로고
    • Fluorescently-labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model
    • Metildi CA, Kaushal S, Luiken GA, Talamini MA, Hoffman RM, Bouvet M. Fluorescently-labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model. J Surg Oncol 2014; 109: 451-458.
    • (2014) J Surg Oncol , vol.109 , pp. 451-458
    • Metildi, C.A.1    Kaushal, S.2    Luiken, G.A.3    Talamini, M.A.4    Hoffman, R.M.5    Bouvet, M.6
  • 12
    • 84903148753 scopus 로고    scopus 로고
    • Advantages of fluorescence-guided laparoscopic surgery of pancreatic cancer labeled with fluorescent anti-carcinoembryonic antigen antibodies in an orthotopic mouse model
    • Metildi CA, Kaushal S, Luiken GA, Hoffman RM, Bouvet M. Advantages of fluorescence-guided laparoscopic surgery of pancreatic cancer labeled with fluorescent anti-carcinoembryonic antigen antibodies in an orthotopic mouse model. J Am Coll Surg 2014; 219: 132-141.
    • (2014) J Am Coll Surg , vol.219 , pp. 132-141
    • Metildi, C.A.1    Kaushal, S.2    Luiken, G.A.3    Hoffman, R.M.4    Bouvet, M.5
  • 13
    • 70149120325 scopus 로고    scopus 로고
    • In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation
    • Kishimoto H, Zhao M, Hayashi K, Urata Y, Tanaka N, Fujiwara T et al. In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation. Proc Natl Acad Sci USA 2009; 106: 14514-14517.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14514-14517
    • Kishimoto, H.1    Zhao, M.2    Hayashi, K.3    Urata, Y.4    Tanaka, N.5    Fujiwara, T.6
  • 14
    • 80051710716 scopus 로고    scopus 로고
    • Tumorselective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection
    • Kishimoto H, Aki R, Urata Y, Bouvet M, Momiyama M, Tanaka N et al. Tumorselective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection. Cell Cycle 2011; 10: 2737-2741.
    • (2011) Cell Cycle , vol.10 , pp. 2737-2741
    • Kishimoto, H.1    Aki, R.2    Urata, Y.3    Bouvet, M.4    Momiyama, M.5    Tanaka, N.6
  • 15
    • 84937988803 scopus 로고    scopus 로고
    • Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of softtissue sarcoma
    • in press
    • Yano S, Miwa S, Kishimoto H, Uehara F, Tazawa H, Toneri M et al. Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of softtissue sarcoma. Oncotarget (in press).
    • Oncotarget
    • Yano, S.1    Miwa, S.2    Kishimoto, H.3    Uehara, F.4    Tazawa, H.5    Toneri, M.6
  • 16
    • 84937988804 scopus 로고    scopus 로고
    • Curative fluorescence-guided surgery of highly-invasive cancer selectively labeled with a killer-reporter adenovirus
    • in press
    • Yano S, Miwa S, Kishimoto H, Toneri M, Hiroshima Y, Yamamoto M et al. Curative fluorescence-guided surgery of highly-invasive cancer selectively labeled with a killer-reporter adenovirus. Mol Ther (in press).
    • Mol Ther
    • Yano, S.1    Miwa, S.2    Kishimoto, H.3    Toneri, M.4    Hiroshima, Y.5    Yamamoto, M.6
  • 17
    • 84859992000 scopus 로고    scopus 로고
    • Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens
    • Suetsugu A, Katz M, Fleming J, Truty M, Thomas R, Moriwaki H et al. Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens. J Cell Biochem 2012; 113: 2290-2295.
    • (2012) J Cell Biochem , vol.113 , pp. 2290-2295
    • Suetsugu, A.1    Katz, M.2    Fleming, J.3    Truty, M.4    Thomas, R.5    Moriwaki, H.6
  • 18
    • 84865692156 scopus 로고    scopus 로고
    • Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice
    • Suetsugu A, Katz M, Fleming J, Truty M, Thomas R, Saji S et al. Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice. Anticancer Res 2012; 32: 3063-3068.
    • (2012) Anticancer Res , vol.32 , pp. 3063-3068
    • Suetsugu, A.1    Katz, M.2    Fleming, J.3    Truty, M.4    Thomas, R.5    Saji, S.6
  • 19
    • 61449249671 scopus 로고    scopus 로고
    • A transgenic red fluorescent proteinexpressing nude mouse for color-coded imaging of the tumor microenvironment
    • Yang M, Reynoso J, Bouvet M, Hoffman RM. A transgenic red fluorescent proteinexpressing nude mouse for color-coded imaging of the tumor microenvironment. J Cell Biochem 2009; 106: 279-284.
    • (2009) J Cell Biochem , vol.106 , pp. 279-284
    • Yang, M.1    Reynoso, J.2    Bouvet, M.3    Hoffman, R.M.4
  • 20
    • 75549083749 scopus 로고    scopus 로고
    • Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice
    • Kim MP, Evans DB, Wang H, Abbruzzese JL, Fleming JB, Gallick GE. Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice. Nat Protoc 2009; 4: 1670-1680.
    • (2009) Nat Protoc , vol.4 , pp. 1670-1680
    • Kim, M.P.1    Evans, D.B.2    Wang, H.3    Abbruzzese, J.L.4    Fleming, J.B.5    Gallick, G.E.6
  • 21
    • 84865031121 scopus 로고    scopus 로고
    • Molecular profiling of direct xenograft tumors established from human pancreatic adenocarcinoma after neoadjuvant therapy
    • Kim MP, Truty MJ, Choi W, Kang Y, Chopin-Lally X, Gallick GE et al. Molecular profiling of direct xenograft tumors established from human pancreatic adenocarcinoma after neoadjuvant therapy. Ann Surg Oncol 2011; 19(Suppl 3): S395-S403.
    • (2011) Ann Surg Oncol , vol.19 , pp. S395-S403
    • Kim, M.P.1    Truty, M.J.2    Choi, W.3    Kang, Y.4    Chopin-Lally, X.5    Gallick, G.E.6
  • 22
    • 0026653874 scopus 로고
    • A metastatic nude-mouse model of human pancreatic cancer constructedorthotopically from histologically intact patient specimens
    • Fu X, Guadagni F, Hoffman RM. A metastatic nude-mouse model of human pancreatic cancer constructedorthotopically from histologically intact patient specimens. Proc Natl Acad Sci USA 1992; 89: 5645-5649.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5645-5649
    • Fu, X.1    Guadagni, F.2    Hoffman, R.M.3
  • 23
    • 0033500248 scopus 로고    scopus 로고
    • Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: A bridge to the clinic
    • Hoffman RM. Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic. Invest New Drugs 1999; 17: 343-359.
    • (1999) Invest New Drugs , vol.17 , pp. 343-359
    • Hoffman, R.M.1
  • 24
    • 0035062436 scopus 로고    scopus 로고
    • Chronologicallyspecific metastatic targeting of human pancreatic tumors in orthotopic models
    • Bouvet M, Yang M, Nardin S, Wang X, Jiang P, Baranov E et al. Chronologicallyspecific metastatic targeting of human pancreatic tumors in orthotopic models. Clin Exp Metastasis 2000; 18: 213-218.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 213-218
    • Bouvet, M.1    Yang, M.2    Nardin, S.3    Wang, X.4    Jiang, P.5    Baranov, E.6
  • 25
    • 0036494543 scopus 로고    scopus 로고
    • Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model
    • Bouvet M, Wang J-W, Nardin SR, Nassirpour R, Yang M, Baranov E et al. Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res 2002; 62: 1534-1540.
    • (2002) Cancer Res , vol.62 , pp. 1534-1540
    • Bouvet, M.1    Wang, J.-W.2    Nardin, S.R.3    Nassirpour, R.4    Yang, M.5    Baranov, E.6
  • 26
    • 0041734667 scopus 로고    scopus 로고
    • A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics
    • Katz MH, Takimoto S, Spivack D, Moossa AR, Hoffman RM, Bouvet M. A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics. J Surg Res 2003; 113: 151-160.
    • (2003) J Surg Res , vol.113 , pp. 151-160
    • Katz, M.H.1    Takimoto, S.2    Spivack, D.3    Moossa, A.R.4    Hoffman, R.M.5    Bouvet, M.6
  • 27
    • 34347222919 scopus 로고    scopus 로고
    • Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time
    • Yang M, Jiang P, Hoffman RM. Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time. Cancer Res 2007; 67: 5195-5200.
    • (2007) Cancer Res , vol.67 , pp. 5195-5200
    • Yang, M.1    Jiang, P.2    Hoffman, R.M.3
  • 28
    • 84869480421 scopus 로고    scopus 로고
    • Multiphoton tomography visualizes collagen fibers in the tumor microenvironment that maintain cancer-cell anchorage and shape
    • Uchugonova A, Zhao M, Weinigel M, Zhang Y, Bouvet M, Hoffman RM et al. Multiphoton tomography visualizes collagen fibers in the tumor microenvironment that maintain cancer-cell anchorage and shape. J Cell Biochem 2013; 114: 99-102.
    • (2013) J Cell Biochem , vol.114 , pp. 99-102
    • Uchugonova, A.1    Zhao, M.2    Weinigel, M.3    Zhang, Y.4    Bouvet, M.5    Hoffman, R.M.6
  • 29
    • 33646230782 scopus 로고    scopus 로고
    • Development of real-time subcellular dynamic multicolor imaging of cancer cell trafficking in live mice with a variable-magnification whole-mouse imaging system
    • Yamauchi K, Yang M, Jiang P, Xu M, Yamamoto N, Tsuchiya H et al. Development of real-time subcellular dynamic multicolor imaging of cancer cell trafficking in live mice with a variable-magnification whole-mouse imaging system. Cancer Res 2006; 66: 4208-4214.
    • (2006) Cancer Res , vol.66 , pp. 4208-4214
    • Yamauchi, K.1    Yang, M.2    Jiang, P.3    Xu, M.4    Yamamoto, N.5    Tsuchiya, H.6
  • 30
    • 84900044348 scopus 로고    scopus 로고
    • Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice
    • Hiroshima Y, Maawy A, Sato S, Murakami T, Uehara F, Miwa S et al. Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice. J Surg Res 2014; 187: 510-517.
    • (2014) J Surg Res , vol.187 , pp. 510-517
    • Hiroshima, Y.1    Maawy, A.2    Sato, S.3    Murakami, T.4    Uehara, F.5    Miwa, S.6
  • 31
    • 84859952919 scopus 로고    scopus 로고
    • Imageable fluorescent metastasis resulting in transgenic GFP mice orthotopically implanted with humanpatient primary pancreatic cancer specimens
    • Suetsugu A, Katz M, Fleming J, Truty M, Thomas R, Saji S et al. Imageable fluorescent metastasis resulting in transgenic GFP mice orthotopically implanted with humanpatient primary pancreatic cancer specimens. Anticancer Res 2012; 32: 1175-1180.
    • (2012) Anticancer Res , vol.32 , pp. 1175-1180
    • Suetsugu, A.1    Katz, M.2    Fleming, J.3    Truty, M.4    Thomas, R.5    Saji, S.6


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