-
1
-
-
79251490374
-
New driver mutations in non-small-cell lung cancer
-
Pao W., Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 2011, 12:175-180.
-
(2011)
Lancet Oncol
, vol.12
, pp. 175-180
-
-
Pao, W.1
Girard, N.2
-
2
-
-
84861594994
-
Oncogenic pathways, molecularly targeted therapies, and highlighted clinical trials in non-small-cell lung cancer (NSCLC)
-
Reungwetwattana T., Weroha S.J., Molina J.R. Oncogenic pathways, molecularly targeted therapies, and highlighted clinical trials in non-small-cell lung cancer (NSCLC). Clin Lung Cancer 2012, 13:252-266.
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 252-266
-
-
Reungwetwattana, T.1
Weroha, S.J.2
Molina, J.R.3
-
3
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A., Siegel R., Xu J., et al. Cancer statistics, 2010. CA Cancer J Clin 2010, 60:277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
-
4
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel R., Naishadham D., Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013, 63:11-30.
-
(2013)
CA Cancer J Clin
, vol.63
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
5
-
-
84908542013
-
Associations between clinical characteristics and oncogene expression in patients with non-small cell lung cancer
-
Han Y., Yu D.P., Zhou S.J., et al. Associations between clinical characteristics and oncogene expression in patients with non-small cell lung cancer. Genet Mol Res 2014, 13:8913-8924.
-
(2014)
Genet Mol Res
, vol.13
, pp. 8913-8924
-
-
Han, Y.1
Yu, D.P.2
Zhou, S.J.3
-
6
-
-
84903585828
-
BRAF mutations in patients with non-small cell lung cancer: a systematic review and meta-analysis
-
Chen D., Zhang L.Q., Huang J.F., et al. BRAF mutations in patients with non-small cell lung cancer: a systematic review and meta-analysis. PLoS One 2014, 9:e101354.
-
(2014)
PLoS One
, vol.9
, pp. e101354
-
-
Chen, D.1
Zhang, L.Q.2
Huang, J.F.3
-
7
-
-
84861863158
-
EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib
-
Corcoran R.B., Ebi H., Turke A.B., et al. EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib. Cancer Discov 2012, 2:227-235.
-
(2012)
Cancer Discov
, vol.2
, pp. 227-235
-
-
Corcoran, R.B.1
Ebi, H.2
Turke, A.B.3
-
8
-
-
79956316170
-
Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations
-
Paik P.K., Arcila M.E., Fara M., et al. Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. JClin Oncol 2011, 29:2046-2051.
-
(2011)
JClin Oncol
, vol.29
, pp. 2046-2051
-
-
Paik, P.K.1
Arcila, M.E.2
Fara, M.3
-
9
-
-
84900829967
-
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
-
Kris M.G., Johnson B.E., Berry L.D., et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA 2014, 311:1998-2006.
-
(2014)
JAMA
, vol.311
, pp. 1998-2006
-
-
Kris, M.G.1
Johnson, B.E.2
Berry, L.D.3
-
10
-
-
84863230465
-
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
-
Prahallad A., Sun C., Huang S., et al. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 2012, 483:100-103.
-
(2012)
Nature
, vol.483
, pp. 100-103
-
-
Prahallad, A.1
Sun, C.2
Huang, S.3
-
11
-
-
84901826745
-
Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations
-
Kinno T., Tsuta K., Shiraishi K., et al. Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations. Ann Oncol 2014, 25:138-142.
-
(2014)
Ann Oncol
, vol.25
, pp. 138-142
-
-
Kinno, T.1
Tsuta, K.2
Shiraishi, K.3
-
12
-
-
80053014471
-
Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations
-
Marchetti A., Felicioni L., Malatesta S., et al. Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. JClin Oncol 2011, 29:3574-3579.
-
(2011)
JClin Oncol
, vol.29
, pp. 3574-3579
-
-
Marchetti, A.1
Felicioni, L.2
Malatesta, S.3
-
13
-
-
84894300510
-
Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer
-
Lin L., Asthana S., Chan E., et al. Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer. Proc Natl Acad Sci U S A 2014, 111:E748-E757.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E748-E757
-
-
Lin, L.1
Asthana, S.2
Chan, E.3
-
14
-
-
17044388155
-
Genetic variation analyses by pyrosequencing
-
Langaee T., Ronaghi M. Genetic variation analyses by pyrosequencing. Mutat Res 2005, 573:96-102.
-
(2005)
Mutat Res
, vol.573
, pp. 96-102
-
-
Langaee, T.1
Ronaghi, M.2
-
15
-
-
67449158731
-
Pyrosequencing method to detect KRAS mutation in formalin-fixed and paraffin-embedded tumor tissues
-
Dufort S., Richard M.J., de Fraipont F. Pyrosequencing method to detect KRAS mutation in formalin-fixed and paraffin-embedded tumor tissues. Anal Biochem 2009, 391:166-168.
-
(2009)
Anal Biochem
, vol.391
, pp. 166-168
-
-
Dufort, S.1
Richard, M.J.2
de Fraipont, F.3
-
16
-
-
82355191818
-
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
-
Sequist L.V., Heist R.S., Shaw A.T., et al. Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice. Ann Oncol 2011, 22:2616-2624.
-
(2011)
Ann Oncol
, vol.22
, pp. 2616-2624
-
-
Sequist, L.V.1
Heist, R.S.2
Shaw, A.T.3
-
17
-
-
78651079558
-
Aplatform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer
-
Su Z., Dias-Santagata D., Duke M., et al. Aplatform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer. JMol Diagn 2011, 13:74-84.
-
(2011)
JMol Diagn
, vol.13
, pp. 74-84
-
-
Su, Z.1
Dias-Santagata, D.2
Duke, M.3
-
18
-
-
84883022821
-
Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer
-
Cardarella S., Ogino A., Nishino M., et al. Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer. Clin Cancer Res 2013, 19:4532-4540.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4532-4540
-
-
Cardarella, S.1
Ogino, A.2
Nishino, M.3
-
19
-
-
84891488352
-
Identification of type II inhibitors targeting BRAF using privileged pharmacophores
-
Zhang Q., Wang J., Wang F., et al. Identification of type II inhibitors targeting BRAF using privileged pharmacophores. Chem Biol Drug Des 2014, 83:27-36.
-
(2014)
Chem Biol Drug Des
, vol.83
, pp. 27-36
-
-
Zhang, Q.1
Wang, J.2
Wang, F.3
-
20
-
-
0037810249
-
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention
-
Chang F., Steelman L.S., Lee J.T., et al. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. Leukemia 2003, 17:1263-1293.
-
(2003)
Leukemia
, vol.17
, pp. 1263-1293
-
-
Chang, F.1
Steelman, L.S.2
Lee, J.T.3
-
21
-
-
84925714296
-
BRAF mutations in non-small-cell lung cancer
-
Smit E. BRAF mutations in non-small-cell lung cancer. JThorac Oncol 2014, 9:1594-1595.
-
(2014)
JThorac Oncol
, vol.9
, pp. 1594-1595
-
-
Smit, E.1
-
22
-
-
84903201668
-
BRAF mutations: signaling, epidemiology, and clinical experience in multiple malignancies
-
Hall R.D., Kudchadkar R.R. BRAF mutations: signaling, epidemiology, and clinical experience in multiple malignancies. Cancer Control 2014, 21:221-230.
-
(2014)
Cancer Control
, vol.21
, pp. 221-230
-
-
Hall, R.D.1
Kudchadkar, R.R.2
-
23
-
-
84937967608
-
FDA approves Zelboraf (vemurafenib) and companion diagnostic for BRAF mutation-positive metastatic melanoma, a deadly form of skin cancer
-
Available at. Accessed November 27, 2013
-
Genentech. FDA approves Zelboraf (vemurafenib) and companion diagnostic for BRAF mutation-positive metastatic melanoma, a deadly form of skin cancer. Available at: . Accessed November 27, 2013. http://www.roche.com/media/store/releases/med-cor-2011-08-17.htm.
-
-
-
-
24
-
-
84868481873
-
Vemurafenib: the first drug approved for BRAF-mutant cancer
-
Bollag G., Tsai J., Zhang J., et al. Vemurafenib: the first drug approved for BRAF-mutant cancer. Nat Rev Drug Discov 2012, 11:873-886.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 873-886
-
-
Bollag, G.1
Tsai, J.2
Zhang, J.3
-
25
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
Sosman J.A., Kim K.B., Schuchter L., et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. NEngl J Med 2012, 366:707-714.
-
(2012)
NEngl J Med
, vol.366
, pp. 707-714
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
-
26
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman P.B., Hauschild A., Robert C., et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. NEngl J Med 2011, 364:2507-2516.
-
(2011)
NEngl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
27
-
-
84873672326
-
Mutations of the BRAF gene in human cancer, by Davies etal. (Nature 2002; 417: 949-954)
-
Millington G.W. Mutations of the BRAF gene in human cancer, by Davies etal. (Nature 2002; 417: 949-954). Clin Exp Dermatol 2013, 38:222-223.
-
(2013)
Clin Exp Dermatol
, vol.38
, pp. 222-223
-
-
Millington, G.W.1
-
28
-
-
84884999688
-
Interim results of phase II study BRF113928 of dabrafenib in BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) patients
-
ASCO Annual Meeting Abstracts 2013
-
Planchard D, Mazieres J, Riely GJ, etal. Interim results of phase II study BRF113928 of dabrafenib in BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) patients. J Clin Oncol, 2013 ASCO Annual Meeting Abstracts 2013;31.
-
(2013)
J Clin Oncol
, pp. 31
-
-
Planchard, D.1
Mazieres, J.2
Riely, G.J.3
-
29
-
-
80054790555
-
BRAF mutations in advanced cancers: clinical characteristics and outcomes
-
El-Osta H., Falchook G., Tsimberidou A., et al. BRAF mutations in advanced cancers: clinical characteristics and outcomes. PLoS One 2011, 6:e25806.
-
(2011)
PLoS One
, vol.6
, pp. e25806
-
-
El-Osta, H.1
Falchook, G.2
Tsimberidou, A.3
-
30
-
-
52149114884
-
The histopathology of BRAF-V600E-mutated lung adenocarcinoma
-
Yousem S.A., Nikiforova M., Nikiforov Y. The histopathology of BRAF-V600E-mutated lung adenocarcinoma. Am J Surg Pathol 2008, 32:1317-1321.
-
(2008)
Am J Surg Pathol
, vol.32
, pp. 1317-1321
-
-
Yousem, S.A.1
Nikiforova, M.2
Nikiforov, Y.3
|