Distal Angiopathy and Atypical Hemolytic Uremic Syndrome: Clinical and Functional Properties of an Anti-Factor H IgAλ Antibody

American Journal of Kidney Diseases

Volumn 66, Issue 2, 2015, Pages 331-336

  Rigothier, Claire ^a,b   Delmas, Yahsou ^a   Roumenina, Lubka T ^c,d,e   Contin Bordes, Cécile ^a   Lepreux, Sébastien ^a,b   Bridoux, Frank ^f,g   Goujon, Jean Michel ^f,g   Bachelet, Thomas ^a   Touchard, Guy ^f,g   Frémeaux Bacchi, Véronique ^c,h   Combe, Christian ^a,b  

^a BORDEAUX UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c CENTRE DE RECHERCHE DES CORDELIERS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f POITIERS UNIVERSITY HOSPITAL   (France)

^g Ctr de Reference des Amyloses Primitives et des Maladies de Depots d'Immunoglobulines Monoclonales   (France)

^h HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

alternative complement pathway; atypical hemolytic uremic syndrome (aHUS); autoantibody; complement activation; complement factor H (CFH); distal angiopathy; factor H antibody; Index Words Gammopathy; macroangiopathy; microvascular injury

Indexed keywords

COMPLEMENT COMPONENT C4D; COMPLEMENT COMPONENT C5B; COMPLEMENT FACTOR H; CONGO RED; ECULIZUMAB; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN A LAMBDA ANTIBODY; UNCLASSIFIED DRUG; IMMUNOGLOBULIN A; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY;

ADULT; ARTICLE; CASE REPORT; CELL SURFACE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; DISEASE ASSOCIATION; DISEASE COURSE; DISTAL ANGIOPATHY; END STAGE RENAL DISEASE; ENDOTHELIUM CELL; FOLLOW UP; HEMOLYTIC ANEMIA; HEMOLYTIC UREMIC SYNDROME; HUMAN; KIDNEY BIOPSY; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PLASMAPHERESIS; PURPURA; REMISSION; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; URINALYSIS; VASCULAR DISEASE; VASCULAR LESION; VASOCONSTRICTION; ATYPICAL HEMOLYTIC UREMIC SYNDROME; COMPLICATION; IMMUNOLOGY; KIDNEY FAILURE, CHRONIC; PARAPROTEINEMIAS; RAYNAUD DISEASE; THROMBOTIC MICROANGIOPATHIES;

ANTIBODIES, MONOCLONAL, HUMANIZED; ATYPICAL HEMOLYTIC UREMIC SYNDROME; COMPLEMENT FACTOR H; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN LIGHT CHAINS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PARAPROTEINEMIAS; PLASMA EXCHANGE; RAYNAUD DISEASE; THROMBOTIC MICROANGIOPATHIES;

EID: 84937975499     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2015.03.039     Document Type: Article

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