Increased aortic intimal proliferation due to MasR deletion in vitro

International Journal of Experimental Pathology

Volumn 96, Issue 3, 2015, Pages 183-187

  Alsaadon, Hiba ^a   Kruzliak, Peter ^b   Smardencas, Arthur ^a   Hayes, Alan ^a   Bader, Michael ^c   Angus, Peter ^d   Herath, Chandana ^d   Zulli, Anthony ^a  

^a VICTORIA UNIVERSITY   (Australia)

^b ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Angiotensin (1 7) Mas receptor; Atherosclerosis; Endothelial function; Intimal thickening

Indexed keywords

MAS RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG; G PROTEIN COUPLED RECEPTOR; ONCOPROTEIN; PROTO-ONCOGENE PROTEINS C-MAS-1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA INTIMA; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONNECTIVE TISSUE; CONTROLLED STUDY; IN VITRO STUDY; MOUSE; NONHUMAN; ORGAN CULTURE TECHNIQUE; PRIORITY JOURNAL; VASCULAR RING; ANIMAL; C57BL MOUSE; DEFICIENCY; GENE DELETION; GENETICS; GENOTYPE; KNOCKOUT MOUSE; METABOLISM; NEOINTIMA; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; THORACIC AORTA; TIME; TISSUE CULTURE TECHNIQUE; VASOCONSTRICTION; VASODILATATION;

ANIMALS; AORTA, THORACIC; CELL PROLIFERATION; GENE DELETION; GENOTYPE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOINTIMA; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; TIME FACTORS; TISSUE CULTURE TECHNIQUES; VASOCONSTRICTION; VASODILATION;

EID: 84937975344     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/iep.12118     Document Type: Article

References (19)

1. Andersson J., Libby P., Hansson G.K. (2010) Adaptive immunity and atherosclerosis. Clin. Immunol. 134, 33-46.
2. Barter P.J., Nicholls S., Rye K.A., Anantharamaiah G., Navab M., Fogelman A.M. (2004) Antiinflammatory properties of HDL. Circ. Res. 95, 764-772.
3. Cable D.G., Caccitolo J.A., Caplice N. et al. (1999) The role of gene therapy for intimal hyperplasia of bypass grafts. Circulation 100, II392-II396.
4. Cogolludo A., Moreno L., Bosca L., Tamargo J., Perez-Vizcaino F. (2003) Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction role of protein kinase Cζ. Circ. Res. 93, 656-663.
5. Davignon J., Ganz P. (2004) Role of endothelial dysfunction in atherosclerosis. Circulation 109, III27-III32.
6. Dinh D.T., Frauman A.G., Johnston C.I., Fabiani M.E. (2001) Angiotensin receptors: distribution, signalling and function. Clin. Sci. 100, 481-492.
7. George A.J., Thomas W.G., Hannan R.D. (2010) The renin-angiotensin system and cancer: old dog, new tricks. Nat. Rev. Cancer 10, 745-759.
8. Gunnett C.A., Berg D.J., Faraci F.M. (1999) Vascular effects of lipopolysaccharide are enhanced in interleukin-10-deficient mice. Stroke 30, 2191-2196.
9. Jaiswal N., Diz D.I., Chappell M.C., Khosla M.C., Ferrario C.M. (1992) Stimulation of endothelial cell prostaglandin production by angiotensin peptides. Characterization of receptors. Hypertension 19, II49.
10. Kucharewicz I., Pawlak R., Matys T., Pawlak D., Buczko W. (2002) Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7). Hypertension 40, 774-779.
11. Lamping K.G., Faraci F.M. (2001) Role of sex differences and effects of endothelial NO synthase deficiency in responses of carotid arteries to serotonin. Arterioscler. Thromb. Vasc. Biol. 21, 523-528.
12. Lemos V.S., Silva D.M., Walther T., Alenina N., Bader M., Santos R.A. (2005) The endothelium-dependent vasodilator effect of the nonpeptide Ang (1-7) mimic AVE 0991 is abolished in the aorta of mas-knockout mice. J. Cardiovasc. Pharmacol. 46, 274-279.
13. Peiró C., Vallejo S., Gembardt F. et al. (2007) Endothelial dysfunction through genetic deletion or inhibition of the G protein-coupled receptor Mas: a new target to improve endothelial function. J. Hypertens. 25, 2421-2425.
14. Polak J.F., Pencina M.J., Pencina K.M., O'Donnell C.J., Wolf P.A., D'Agostino R.B. Sr (2011) Carotid-wall intima-media thickness and cardiovascular events. N. Engl. J. Med. 365, 213-221.
15. Santos R.A., e Silva A.C.S., Maric C. et al. (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc. Natl Acad. Sci. USA 100, 8258-8263.
16. Tallant E.A., Diz D.I., Ferrario C.M. (1999) Antiproliferative actions of angiotensin-(1-7) in vascular smooth muscle. Hypertension 34, 950-957.
17. Tesanovic S., Vinh A., Gaspari T.A., Casley D., Widdop R.E. (2010) Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol. 30, 1606-1613.
18. Xu P., Costa-Goncalves A.C., Todiras M., Rabelo L.A., Sampaio W.O., Moura M.M., Santos S.S., Luft F.C., Bader M., Gross V., Alenina N., Santos R.A. (2008) Endothelial dysfunction and elevated blood pressure in MAS gene-deleted mice. Hypertension. 51, 574-580.
19. Zhang F., Hu Y., Xu Q., Ye S. (2010) Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration. PLoS One 5, e12323.