The role of gene therapy for intimal hyperplasia of bypass grafts

Circulation

Volumn 100, Issue 19 SUPPL., 1999, Pages

  Cable, David G ^a   Caccitolo, James A ^a   Caplice, Noel ^a   O'Brien, Timothy ^a   Simari, Robert D ^a   Daly, Richard C ^a   Dearani, Joseph A ^a   Mullany, Charles J ^a   Orszulak, Thomas A ^a   Schaff, Hartzell V ^a  

^a MAYO CLINIC   (United States)

Author keywords

Gene transfer; Mammary arteries; Nitric oxide; Organ culture; Radial artery; Saphenous vein

Indexed keywords

ADENOVIRUS; ARTERY INTIMA PROLIFERATION; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; CORONARY ARTERY SURGERY; ESCHERICHIA COLI; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN TISSUE; INTERNAL MAMMARY ARTERY; ORGAN CULTURE; PRIORITY JOURNAL; RADIAL ARTERY; SAPHENOUS VEIN;

EID: 5444269236     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.cir.100.suppl_2.ii-392     Document Type: Article

References (28)

1. Loop FD, Lytle BW, Cosgrove DM, Stewart RW, Goormastic M, Williams GW, Golding LA, Gill CC, Taylor PC, Sheldon WC, Proudfit WL. Influence of the internal-mammary-artery graft on 10-year survival and other cardiac events. N Engl J Med. 1986;314:1-6.
2. Acar C, Jebara VA, Portoghese M, Beyssen B, Pagny JY, Grare P, Chachques JC, Fabiani JN, Deloche A, Guermonprez JL, Carpentier AF. Revival of the radial artery for coronary artery bypass grafting. Ann Thorac Surg. 1992;54:652-659.
3. FitzGibbon GM, Leach AJ, Keon WJ, Burton JR, Kafka HP. Coronary bypass graft fate. Angiographic study of 1,179 vein grafts early, 1 year, and 5 years after operation. J Thorac Cardiovasc Surg. 1986; 91:773-778.
4. Grondin CM, Campeau L, Lesperance J, Solymoss BC, Vouhe P, Castonguay YR, Meere C, Bourassa MG. Atherosclerotic changes in coronary vein grafts 6 years after operation: angiographic aspect in 110 patients. J Thorac Cardiovasc Surg. 1979;77:24-31.
5. Weintraub WS, Jones EL, Craver JM, Guyton RA. Frequency of repeat coronary bypass or coronary angioplasty after coronary artery bypass surgery using saphenous venous grafts. Am J Cardiol. 1994; 73:103-112.
6. Akins CW, Buckley MJ, Daggett WM, Hilgenberg AD, Vlahakes GJ, Torchiana DF, Austen WG. Reoperative coronary grafting: changing patient profiles, operative indications, techniques, and results. Ann Thorac Surg. 1994;58:359-364.
7. Pederson DC, Bowyer DE. Endothelial injury and healing in vitro. Studies using an organ culture system. Am J Pathol. 1985;119: 264-272.
8. Cable DG, O'Brien T, Schaff HV, Pompili VJ. Recombinant endothelial nitric oxide synthase-transduced human saphenous veins: gene therapy to augment nitric oxide production in bypass conduits. Circulation. 1997; 96(suppl II):II-173-II-178.
9. Cable DG, O'Brien T, Kullo IJ, Schwartz RS, Schaff HV, Pompili VJ. Expression and function of a recombinant endothelial nitric oxide synthase gene in porcine coronary arteries. Cardiovasc Res. 1997;35: 553-559.
10. Slomp J, Gittenberger-deGroot AC, van Munsteren JC, Huysmans HA, van Bockel JH, van Hinsbergh VW, Poelmann RE. Nature and origin of the neointima in whole vessel wall organ culture of the human saphenous vein. Virchows Arch. 1996;428:59-67.
11. Porter KE, Varty K, Jones L, Bell PR, London NJ. Human saphenous vein organ culture: a useful model of intimal hyperplasia? Eur J Vasc Endovasc Surg. 1996;11:48-58.
12. Soyombo AA, Angelini GD, Bryan AJ, Jasani B, Newby AC. Intimal proliferation in an organ culture of human saphenous vein. Am J Pathol. 1990;137:1401-1410.
13. Holt CM, Francis SE, Newby AC, Rogers S, Gadsdon PA, Taylor T, Angelini GD. Comparison of response to injury in organ culture of human saphenous vein and internal mammary artery. Ann Thorac Surg. 1993; 55:1522-1528.
14. Masood I, Porter KE, London NJ. Endothelin-1 is a mediator of intimai hyperplasia in organ culture of human saphenous vein. Br J Surg. 1997; 84:499-503.
15. Jeremy JY, Birkett SD, Bryan AJ, Angelini GD. The influence of surgical preparation on cyclic nucleotide synthesis in an organ culture of human saphenous vein. Eur J Vasc Endovasc Surg. 1997;13:72-78.
16. Soyombo AA, Angelini GD, Newby AC. Neointima formation is promoted by surgical preparation and inhibited by cyclic nucleotides in human saphenous vein organ cultures. J Thorac Cardiovasc Surg. 1995; 109:2-12.
17. Allen KE, Varty K, Jones L, Sayers RD, Bell PR, London NJ. Human venous endothelium can promote intimai hyperplasia in a paracrine manner. J Vasc Surg. 1994;19:577-584.
18. Varty K, Porter K, Bell PR, London NJ. Vein morphology and bypass graft stenosis. Br J Surg. 1996;83:1375-1379.
19. van Son JA, Smedts F, Vincent JG, van Lier HJ, Kubat K. Comparative anatomic studies of various arterial conduits for myocardial revascularization. J Thorac Cardiovasc Surg. 1990;99:703-707.
20. Curtis JJ, Stoney WS, Alford WC Jr, Burrus GR, Thomas CS Jr. Intimai hyperplasia: a cause of radial artery aortocoronary bypass graft failure. Ann Thorac Surg. 1975;20:628-635.
21. Kaufer E, Factor SM, Frame R, Brodman RF. Pathology of the radial and internal thoracic arteries used as coronary artery bypass grafts. Ann Thorac Surg. 1997;63:1118-1122.
22. Angelini GD, Breckenridge IM, Psaila JV, Williams HM, Henderson AH, Newby AC. Preparation of human saphenous vein for coronary artery bypass grafting impairs its capacity to produce prostacyclin. Cardiovasc Res. 1987;21:28-33.
23. LoGerfo FW, Quist WC, Cantelmo NL, Haudenschild CC. Integrity of vein grafts as a function of initial intimal and medial preservation. Circulation. 1983;68(suppl II):II-117-II-124.
24. Newman KD, Dunn PF, Owens JW, Schulick AH, Virmani R, Sukhova G, Libby P, Dichek DA. Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia. J Clin Invest. 1995;96:2955-2965.
25. McCray PB Jr, Armstrong K, Zabner J, Miller DW, Koretzky GA, Couture L, Robillard JE, Smith AE, Welsh MJ. Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo. J Clin Invest. 1995;95:2620-2632.
26. von der Leyen HE, Gibbons GH, Morishita R, Lewis NP, Zhang L, Nakajima M, Kaneda Y, Cooke JP, Dzau VJ. Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl Acad Sci U S A. 1995;92:1137-1141.
27. Cable DG, Caccitolo JA, Pearson PJ, O'Brien T, Mullany CJ, Daly RC, Orszulak TA, Schaff HV. New approaches to prevention and treatment of radial artery graft vasospasm. Circulation. 1998;98(suppl II:II-15-II-21.
28. George SJ, Johnson JL, Angelini GD, Newby AC, Baker AH. Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein. Hum Gene Ther. 1998;9:867-877.