Inhibition of the alternative complement pathway preserves photoreceptors after retinal injury

Science Translational Medicine

Volumn 7, Issue 297, 2015, Pages

  Sweigard, J Harry ^a   Matsumoto, Hidetaka ^a   Smith, Kaylee E ^a   Kim, Leo A ^b   Paschalis, Eleftherios I ^b   Okonuki, Yoko ^a   Castillejos, Alexandra ^a   Kataoka, Keiko ^a   Hasegawa, Eiichi ^a   Yanai, Ryoji ^a   Husain, Deeba ^a   Lambris, John D ^c   Vavvas, Demetrios ^a   Miller, Joan W ^a   Connor, Kip M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; CD59 ANTIGEN; DECAY ACCELERATING FACTOR; LEUKOCYTE ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT INHIBITION; CONTROLLED STUDY; HUMAN; HYPOXIA; IMMUNOPATHOGENESIS; INNATE IMMUNITY; MOUSE; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA DETACHMENT; RETINA INJURY; ANIMAL; C57BL MOUSE; DISEASE MODEL; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHOTORECEPTOR CELL; RETINA; RETINA DEGENERATION;

ANIMALS; ANTIGENS, CD; CELL DEATH; COMPLEMENT PATHWAY, ALTERNATIVE; DISEASE MODELS, ANIMAL; HUMANS; HYPOXIA; MICE, INBRED C57BL; PHOTORECEPTOR CELLS, VERTEBRATE; RETINA; RETINAL DEGENERATION;

EID: 84937951729     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aab1482     Document Type: Article

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