Membrane cofactor protein (MCP; CD46) expression in transgenic mice

Clinical and Experimental Immunology

Volumn 124, Issue 2, 2001, Pages 180-189

  Kemper, C ^a   Leung, M ^a   Stephensen, C B ^b   Pinkert, C A ^c   Liszewski, M K ^a   Cattaneo, R ^d   Atkinson, J P ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Complement system; MCP (CD46) transgenic mice; Measles virus receptor; Membrane cofactor protein (MCP; CD46)

Indexed keywords

MEMBRANE COFACTOR PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVARY GLAND; TISSUE DISTRIBUTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD46; BLOOD CELLS; ERYTHROCYTES; FEMALE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; PROTEIN ISOFORMS; RECEPTORS, VIRUS; RNA SPLICING; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0034961941     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2001.01458.x     Document Type: Article

References (44)

1. Identification of an additional class of C3-binding membrane proteins of human peripheral blood leukocytes and cell lines
2. Functional properties of membrane cofactor protein of complement
3. Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism
4. Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus
5. The human CD46 molecule is a receptor for measles virus (Edmonton strain)
6. Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus
7. Membrane cofactor protein (MCP; CD46) is a keratinocyte receptor for the M protein of group A streptococcus
8. Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria
9. CD46 is a cellular receptor for human Herpesvirus 6
10. Complement in human reproduction: Activation and control
11. The role of complement component C3b and its receptors in sperm-oocyte interaction
12. Possible association of infertility with sperm-specific abnormality of CD46
13. Membrane cofactor protein of the complement system: Alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms which correlate with protein phenotype
14. CD46, a primate-specific receptor for measles virus
15. Membrane cofactor protein (MCP or CD46): Newest member of the regulators of the complement activation gene cluster
16. Human membrane cofactor protein (MCP, CD46): Multiple isoforms and functions
17. A polymorphism of the complement regulatory protein MCP (membrane cofactor protein or gp45-70)
18. Membrane cofactor protein (MCP) of the complement system: A Hind III RFLP that correlates with expression polymorphism
19. Strong associations between RFLP and protein polymorphism for CD46
20. The evolution of mouse and human complement C3-binding proteins: Divergence of form but conservation of function
21. Measles virus spread and pathogenesis in genetically modified mice
22. Analysis of the human regulators of complement activation (RCA) gene cluster with yeast artificial chromosomes (YACs)
23. A membrane cofactor protein transgenic mouse model for the study of discordant xenograft rejection
24. Measles virus infection in a transgenic model: Virus-induced immunosuppression and central nervous system disease
25. A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on human chromosome 1
26. Membrane cofactor protein (MCP; CD46): Isoforms differ in protection against the classical pathway of complement
27. Human complement regulator expression by the normal female reproductive tract
28. MSc Thesis
29. Selective expression of a subset of measles virus receptor-competent CD46 isoforms in human brain
30. Identification and quantification of complement regulator CD46 on normal human tissue
31. Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing
32. Characterization of CR1 and membrane cofactor protein-like proteins of two primates
33. Membrane cofactor protein: Importance of N- and O-glycosylation for complement regulatory function
34. Transgenic expression of a CD46 (membrane cofactor protein) minigene: Studies of xenotransplantation and measles virus infection
35. Transgenic mice expressing human measles virus receptor (CD46) provide cell exhibiting different permissivities to MV infection
36. The regulation of membrane cofactor protein (CD46) expression by the 3 (untranslated region in transgenic mice)
37. A transgenic mouse model for measles virus infection of the brain
38. Role of CD46 in measles virus infection in CD46 transgenic mice
39. Ontogeny of membrane cofactor protein: Phenotypic divergence in the fetal heart
40. Cell signaling by the type IV pili of pathogenic Neisseria
41. CD46 (membrane cofactor protein) associates with multiple β1 integrins and tetraspans
42. Molecular cloning of a murine homologue of membrane cofactor protein (CD46): Preferential expression in testicular germ cells
43. Lymphatic dissemination and comparative pathology of recombinant measles viruses in genetically modified mice
44. A critical role for the murine complement regulator Crry in fetomaternal tolerance