Functionalized PHB granules provide the basis for the efficient side-chain cleavage of cholesterol and analogs in recombinant Bacillus megaterium

Microbial Cell Factories

Volumn 14, Issue 1, 2015, Pages

  Gerber, Adrian ^a   Kleser, Michael ^a   Biedendieck, Rebekka ^b   Bernhardt, Rita ^a   Hannemann, Frank ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

Bacillus megaterium; Cholesterol; Cytochrome P450; PHB; Pregnenolone

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 7 DEHYDROCHOLESTEROL; 7 DEHYDROPREGNENOLONE; CHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; POLY(3 HYDROXYBUTYRIC ACID); PREGNENOLONE; PREGNENOLONE DERIVATIVE; PROTEIN PHAC; SAPONIN; SITOSTEROL; TRANSFERASE; UNCLASSIFIED DRUG; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; HYDROXYBUTYRIC ACID; POLY-BETA-HYDROXYBUTYRATE; POLYESTER; QUILLAJA SAPONIN; RECOMBINANT PROTEIN;

ARTICLE; BACILLUS MEGATERIUM; BIOACCUMULATION; CARBON STORAGE; CATALYSIS; CHOLESTEROL METABOLISM; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; IN VIVO STUDY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; BIOCATALYSIS; BIOSYNTHESIS; BIOTRANSFORMATION; CHEMISTRY; GENETICS; METABOLISM;

BACILLUS MEGATERIUM; BACTERIA (MICROORGANISMS); POSIBACTERIA; QUILLAJA; VERTEBRATA;

BACILLUS MEGATERIUM; BETA-CYCLODEXTRINS; BIOCATALYSIS; BIOTRANSFORMATION; CHOLESTEROL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; HYDROXYBUTYRATES; POLYESTERS; PREGNENOLONE; QUILLAJA SAPONINS; RECOMBINANT PROTEINS;

EID: 84937927323     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0300-y     Document Type: Article

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