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Volumn 21, Issue 5, 2016, Pages 701-706

Neurexin 1 (NRXN1) splice isoform expression during human neocortical development and aging

Author keywords

[No Author keywords available]

Indexed keywords

NEUREXIN; NEUREXIN 1; NEUREXIN 1 ALPHA; NEUREXIN 1 BETA; UNCLASSIFIED DRUG; ISOPROTEIN; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; NRXN1 PROTEIN, HUMAN;

EID: 84937916250     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2015.107     Document Type: Article
Times cited : (40)

References (50)
  • 3
    • 67349182343 scopus 로고    scopus 로고
    • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes
    • Glessner JT, Wang K, Cai G, Korvatska O, Kim CE, Wood S et al. Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature 2009; 459: 569-573
    • (2009) Nature , vol.459 , pp. 569-573
    • Glessner, J.T.1    Wang, K.2    Cai, G.3    Korvatska, O.4    Kim, C.E.5    Wood, S.6
  • 4
    • 84878244184 scopus 로고    scopus 로고
    • Molecular and clinical characterization of 25 individuals with exonic deletions of NRXN1 and comprehensive review of the literature
    • Bena F, Bruno DL, Eriksson M, van Ravenswaaij-Arts C, Stark Z, Dijkhuizen T et al. Molecular and clinical characterization of 25 individuals with exonic deletions of NRXN1 and comprehensive review of the literature. Am J Med Genet 2013; 162B: 388-403
    • (2013) Am J Med Genet , vol.162 B , pp. 388-403
    • Bena, F.1    Bruno, D.L.2    Eriksson, M.3    Van Ravenswaaij-Arts, C.4    Stark, Z.5    Dijkhuizen, T.6
  • 5
    • 77952691843 scopus 로고    scopus 로고
    • Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders
    • Ching MS, Shen Y, Tan WH, Jeste SS, Morrow EM, Chen X et al. Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders. Am J Med Genet 2010; 153B: 937-947
    • (2010) Am J Med Genet , vol.153 B , pp. 937-947
    • Ching, M.S.1    Shen, Y.2    Tan, W.H.3    Jeste, S.S.4    Morrow, E.M.5    Chen, X.6
  • 7
    • 84901066491 scopus 로고    scopus 로고
    • Single exonresolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes
    • Tucker T, Zahir FR, Griffith M, Delaney A, Chai D, Tsang E et al. Single exonresolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes. Eur J Hum Genet 2014; 22: 792-800
    • (2014) Eur J Hum Genet , vol.22 , pp. 792-800
    • Tucker, T.1    Zahir, F.R.2    Griffith, M.3    Delaney, A.4    Chai, D.5    Tsang, E.6
  • 8
    • 38349106160 scopus 로고    scopus 로고
    • Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia
    • Kirov G, Gumus D, Chen W, Norton N, Georgieva L, Sari M et al. Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet 2008; 17: 458-465
    • (2008) Hum Mol Genet , vol.17 , pp. 458-465
    • Kirov, G.1    Gumus, D.2    Chen, W.3    Norton, N.4    Georgieva, L.5    Sari, M.6
  • 10
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • International Schizophrenia C. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008; 455: 237-241
    • (2008) Nature , vol.455 , pp. 237-241
    • International Schizophrenia, C.1
  • 11
    • 67649148483 scopus 로고    scopus 로고
    • Pharmacogenetics of antipsychotic response in the CATIE trial: A candidate gene analysis
    • Need AC, Keefe RS, Ge D, Grossman I, Dickson S, McEvoy JP et al. Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Eur J Hum Genet 2009; 17: 946-957
    • (2009) Eur J Hum Genet , vol.17 , pp. 946-957
    • Need, A.C.1    Keefe, R.S.2    Ge, D.3    Grossman, I.4    Dickson, S.5    McEvoy, J.P.6
  • 14
    • 42349088634 scopus 로고    scopus 로고
    • Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
    • Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM et al. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 2008; 320: 539-543
    • (2008) Science , vol.320 , pp. 539-543
    • Walsh, T.1    McClellan, J.M.2    McCarthy, S.E.3    Addington, A.M.4    Pierce, S.B.5    Cooper, G.M.6
  • 18
    • 84904463987 scopus 로고    scopus 로고
    • Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia
    • Jenkins A, Apud JA, Zhang F, Decot H, Weinberger DR, Law AJ. Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia. Neuropsychopharmacology 2014; 39: 2170-2178
    • (2014) Neuropsychopharmacology , vol.39 , pp. 2170-2178
    • Jenkins, A.1    Apud, J.A.2    Zhang, F.3    Decot, H.4    Weinberger, D.R.5    Law, A.J.6
  • 19
    • 84904960520 scopus 로고    scopus 로고
    • Copy number variants and therapeutic response to antidepressant medication in major depressive disorder
    • Tansey KE, Rucker JJ, Kavanagh DH, Guipponi M, Perroud N, Bondolfi G et al. Copy number variants and therapeutic response to antidepressant medication in major depressive disorder. Pharmacogenomics J 2014; 14: 395-399
    • (2014) Pharmacogenomics J , vol.14 , pp. 395-399
    • Tansey, K.E.1    Rucker, J.J.2    Kavanagh, D.H.3    Guipponi, M.4    Perroud, N.5    Bondolfi, G.6
  • 20
    • 44349192747 scopus 로고    scopus 로고
    • Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers
    • Nussbaum J, Xu Q, Payne TJ, Ma JZ, Huang W, Gelernter J et al. Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers. Hum Mol Genet 2008; 17: 1569-1577
    • (2008) Hum Mol Genet , vol.17 , pp. 1569-1577
    • Nussbaum, J.1    Xu, Q.2    Payne, T.J.3    Ma, J.Z.4    Huang, W.5    Gelernter, J.6
  • 21
    • 84946495594 scopus 로고    scopus 로고
    • The contribution of rare and common variants in 30 genes to risk nicotine dependence
    • Yang J, Wang S, Yang Z, Hodgkinson CA, Iarikova P, Ma JZ et al. The contribution of rare and common variants in 30 genes to risk nicotine dependence. Mol Psychiatry 2014; doi: 10.1038/mp.2014.156; e-pub ahead of print
    • (2014) Mol Psychiatry
    • Yang, J.1    Wang, S.2    Yang, Z.3    Hodgkinson, C.A.4    Iarikova, P.5    Ma, J.Z.6
  • 22
    • 0036210068 scopus 로고    scopus 로고
    • Analysis of the human neurexin genes: Alternative splicing and the generation of protein diversity
    • Rowen L, Young J, Birditt B, Kaur A, Madan A, Philipps DL et al. Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity. Genomics 2002; 79: 587-597
    • (2002) Genomics , vol.79 , pp. 587-597
    • Rowen, L.1    Young, J.2    Birditt, B.3    Kaur, A.4    Madan, A.5    Philipps, D.L.6
  • 23
    • 0031983653 scopus 로고    scopus 로고
    • Neurexins: Three genes and 1001 products
    • Missler M, Sudhof TC. Neurexins: three genes and 1001 products. Trends Genet 1998; 14: 20-26
    • (1998) Trends Genet , vol.14 , pp. 20-26
    • Missler, M.1    Sudhof, T.C.2
  • 24
    • 0036270811 scopus 로고    scopus 로고
    • Structure and evolution of neurexin genes: Insight into the mechanism of alternative splicing
    • Tabuchi K, Sudhof TC. Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing. Genomics 2002; 79: 849-859
    • (2002) Genomics , vol.79 , pp. 849-859
    • Tabuchi, K.1    Sudhof, T.C.2
  • 25
    • 54049091941 scopus 로고    scopus 로고
    • Neuroligins and neurexins link synaptic function to cognitive disease
    • Sudhof TC. Neuroligins and neurexins link synaptic function to cognitive disease. Nature 2008; 455: 903-911
    • (2008) Nature , vol.455 , pp. 903-911
    • Sudhof, T.C.1
  • 26
    • 11144352245 scopus 로고    scopus 로고
    • Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins
    • Graf ER, Zhang X, Jin SX, Linhoff MW, Craig AM. Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Cell 2004; 119: 1013-1026
    • (2004) Cell , vol.119 , pp. 1013-1026
    • Graf, E.R.1    Zhang, X.2    Jin, S.X.3    Linhoff, M.W.4    Craig, A.M.5
  • 27
    • 0033514448 scopus 로고    scopus 로고
    • Neuroligin 1 is a postsynaptic celladhesion molecule of excitatory synapses
    • Song JY, Ichtchenko K, Sudhof TC, Brose N. Neuroligin 1 is a postsynaptic celladhesion molecule of excitatory synapses. Proc Natl Acad Sci USA 1999; 96: 1100-1105
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1100-1105
    • Song, J.Y.1    Ichtchenko, K.2    Sudhof, T.C.3    Brose, N.4
  • 28
    • 7244232730 scopus 로고    scopus 로고
    • Neuroligin 2 is exclusively localized to inhibitory synapses
    • Varoqueaux F, Jamain S, Brose N. Neuroligin 2 is exclusively localized to inhibitory synapses. Eur J Cell Biol 2004; 83: 449-456
    • (2004) Eur J Cell Biol , vol.83 , pp. 449-456
    • Varoqueaux, F.1    Jamain, S.2    Brose, N.3
  • 29
    • 26944444692 scopus 로고    scopus 로고
    • A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins
    • Boucard AA, Chubykin AA, Comoletti D, Taylor P, Sudhof TC. A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. Neuron 2005; 48: 229-236
    • (2005) Neuron , vol.48 , pp. 229-236
    • Boucard, A.A.1    Chubykin, A.A.2    Comoletti, D.3    Taylor, P.4    Sudhof, T.C.5
  • 30
    • 77952720668 scopus 로고    scopus 로고
    • Neurexins physically and functionally interact with GABA(A) receptors
    • Zhang C, Atasoy D, Arac D, Yang X, Fucillo MV, Robison AJ et al. Neurexins physically and functionally interact with GABA(A) receptors. Neuron 2010; 66: 403-416
    • (2010) Neuron , vol.66 , pp. 403-416
    • Zhang, C.1    Atasoy, D.2    Arac, D.3    Yang, X.4    Fucillo, M.V.5    Robison, A.J.6
  • 31
    • 79960146777 scopus 로고    scopus 로고
    • Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia
    • Sun C, Cheng MC, Qin R, Liao DL, Chen TT, Koong FJ et al. Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia. Hum Mol Genet 2011; 20: 3042-3051
    • (2011) Hum Mol Genet , vol.20 , pp. 3042-3051
    • Sun, C.1    Cheng, M.C.2    Qin, R.3    Liao, D.L.4    Chen, T.T.5    Koong, F.J.6
  • 32
    • 0037656313 scopus 로고    scopus 로고
    • Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
    • Jamain S, Quach H, Betancur C, Rastam M, Colineaux C, Gillberg IC et al. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet 2003; 34: 27-29
    • (2003) Nat Genet , vol.34 , pp. 27-29
    • Jamain, S.1    Quach, H.2    Betancur, C.3    Rastam, M.4    Colineaux, C.5    Gillberg, I.C.6
  • 33
    • 33646240854 scopus 로고    scopus 로고
    • Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease
    • Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R et al. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proc Natl Acad Sci USA 2006; 103: 6747-6752
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6747-6752
    • Law, A.J.1    Lipska, B.K.2    Weickert, C.S.3    Hyde, T.M.4    Straub, R.E.5    Hashimoto, R.6
  • 34
    • 77957260622 scopus 로고    scopus 로고
    • Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain
    • Kao WT, Wang Y, Kleinman JE, Lipska BK, Hyde TM, Weinberger DR et al. Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain. Proc Natl Acad Sci USA 2010; 107: 15619-15624
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15619-15624
    • Kao, W.T.1    Wang, Y.2    Kleinman, J.E.3    Lipska, B.K.4    Hyde, T.M.5    Weinberger, D.R.6
  • 35
    • 0038407848 scopus 로고    scopus 로고
    • Trajectories of brain development: Point of vulnerability or window of opportunity?
    • Andersen SL. Trajectories of brain development: point of vulnerability or window of opportunity?. Neurosci Biobehav Rev 2003; 27: 3-18
    • (2003) Neurosci Biobehav Rev , vol.27 , pp. 3-18
    • Andersen, S.L.1
  • 37
    • 0018376668 scopus 로고
    • Synaptic density in human frontal cortex - Developmental changes and effects of aging
    • Huttenlocher PR. Synaptic density in human frontal cortex - developmental changes and effects of aging. Brain Res 1979; 163: 195-205
    • (1979) Brain Res , vol.163 , pp. 195-205
    • Huttenlocher, P.R.1
  • 38
    • 0028958250 scopus 로고
    • Neurexins are differentially expressed in the embryonic nervous system of mice
    • Puschel AW, Betz H. Neurexins are differentially expressed in the embryonic nervous system of mice. J Neurosci 1995; 15: 2849-2856
    • (1995) J Neurosci , vol.15 , pp. 2849-2856
    • Puschel, A.W.1    Betz, H.2
  • 39
    • 31944444571 scopus 로고    scopus 로고
    • Expression patterns of neurexin-1 and neuroligins in brain and retina of the chick embryo: Neuroligin-3 is absent in retina
    • Paraoanu LE, Becker-Roeck M, Christ E, Layer PG. Expression patterns of neurexin-1 and neuroligins in brain and retina of the chick embryo: Neuroligin-3 is absent in retina. Neurosci Lett 2006; 395: 114-117
    • (2006) Neurosci Lett , vol.395 , pp. 114-117
    • Paraoanu, L.E.1    Becker-Roeck, M.2    Christ, E.3    Layer, P.G.4
  • 42
    • 84455200617 scopus 로고    scopus 로고
    • SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1
    • Iijima T, Wu K, Witte H, Hanno-Iijima Y, Glatter T, Richard S et al. SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1. Cell 2011; 147: 1601-1614
    • (2011) Cell , vol.147 , pp. 1601-1614
    • Iijima, T.1    Wu, K.2    Witte, H.3    Hanno-Iijima, Y.4    Glatter, T.5    Richard, S.6
  • 43
    • 79954529302 scopus 로고    scopus 로고
    • Dynamic changes in neurexins' alternative splicing: Role of Rho-Associated protein kinases and relevance to memory formation
    • Rozic G, Lupowitz Z, Piontkewitz Y, Zisapel N. Dynamic changes in neurexins' alternative splicing: role of Rho-Associated protein kinases and relevance to memory formation. PloS One 2011; 6: e18579
    • (2011) PloS One , vol.6 , pp. e18579
    • Rozic, G.1    Lupowitz, Z.2    Piontkewitz, Y.3    Zisapel, N.4
  • 44
    • 38349098974 scopus 로고    scopus 로고
    • Induction of GABAergic postsynaptic differentiation by alpha-neurexins
    • Kang Y, Zhang X, Dobie F, Wu H, Craig AM. Induction of GABAergic postsynaptic differentiation by alpha-neurexins. J Biol Chem 2008; 283: 2323-2334
    • (2008) J Biol Chem , vol.283 , pp. 2323-2334
    • Kang, Y.1    Zhang, X.2    Dobie, F.3    Wu, H.4    Craig, A.M.5
  • 45
    • 33745994650 scopus 로고    scopus 로고
    • Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex
    • Chih B, Gollan L, Scheiffele P. Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex. Neuron 2006; 51: 171-178
    • (2006) Neuron , vol.51 , pp. 171-178
    • Chih, B.1    Gollan, L.2    Scheiffele, P.3
  • 46
    • 33646464124 scopus 로고    scopus 로고
    • Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain
    • Graf ER, Kang Y, Hauner AM, Craig AM. Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain. J Neurosci 2006; 26: 4256-4265
    • (2006) J Neurosci , vol.26 , pp. 4256-4265
    • Graf, E.R.1    Kang, Y.2    Hauner, A.M.3    Craig, A.M.4
  • 47
    • 77953206739 scopus 로고    scopus 로고
    • LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development
    • Siddiqui TJ, Pancaroglu R, Kang Y, Rooyakkers A, Craig AM. LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development. J Neurosci 2010; 30: 7495-7506
    • (2010) J Neurosci , vol.30 , pp. 7495-7506
    • Siddiqui, T.J.1    Pancaroglu, R.2    Kang, Y.3    Rooyakkers, A.4    Craig, A.M.5
  • 48
    • 84908133393 scopus 로고    scopus 로고
    • Perinatal exposure to bisphenol-A impairs spatial memory through upregulation of neurexin1 and neuroligin3 expression in male mouse brain
    • Kumar D, Thakur MK. Perinatal exposure to bisphenol-A impairs spatial memory through upregulation of neurexin1 and neuroligin3 expression in male mouse brain. PloS One 2014; 9: e110482
    • (2014) PloS One , vol.9 , pp. e110482
    • Kumar, D.1    Thakur, M.K.2
  • 49
    • 84901666421 scopus 로고    scopus 로고
    • Copy number variant study of bipolar disorder in Canadian and UK populations implicates synaptic genes
    • Noor A, Lionel AC, Cohen-Woods S, Moghimi N, Rucker J, Fennell A et al. Copy number variant study of bipolar disorder in Canadian and UK populations implicates synaptic genes. Am J Med Genet 2014; 165B: 303-313
    • (2014) Am J Med Genet , vol.165 B , pp. 303-313
    • Noor, A.1    Lionel, A.C.2    Cohen-Woods, S.3    Moghimi, N.4    Rucker, J.5    Fennell, A.6


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