Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells

Experimental Neurology

Volumn 271, Issue , 2015, Pages 423-431

  Fujiwara, Naruyoshi ^a   Shimizu, Jun ^a   Takai, Kenji ^a   Arimitsu, Nagisa ^a   Ueda, Yuji ^a   Wakisaka, Sueshige ^a   Suzuki, Tomoko ^a   Suzuki, Noboru ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cholinergic neuron; Dementia; GABAergic neuron; Human iPS; Nerve regeneration; Transplantation

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; AMYLOID PRECURSOR PROTEIN; BUNGAROTOXIN RECEPTOR; CHOLINE ACETYLTRANSFERASE; NEUROTRANSMITTER; PROTEIN C FOS; PROTEIN KINASE B; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; NERVE PROTEIN; ONCOPROTEIN; VIAAT PROTEIN, RAT;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CHOLINERGIC NERVE CELL; COGNITION; COGNITIVE DEFECT; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STEM CELL TRANSPLANTATION; ANIMAL; COGNITION DISORDERS; CONVALESCENCE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; MAZE TEST; METABOLISM; NERVE CELL; PHYSIOLOGY; TIME; TRANSGENIC MOUSE;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHOLINE O-ACETYLTRANSFERASE; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MAZE LEARNING; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONS; ONCOGENE PROTEIN V-AKT; RECEPTORS, GABA; RECOVERY OF FUNCTION; STEM CELL TRANSPLANTATION; TIME FACTORS; VESICULAR INHIBITORY AMINO ACID TRANSPORT PROTEINS;

EID: 84937908832     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2015.07.008     Document Type: Article

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