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Volumn 119, Issue 2, 2015, Pages 148-156

Attenuation of Ca2+ homeostasis, oxidative stress, and mitochondrial dysfunctions in diabetic rat heart: Insulin therapy or aerobic exercise?

Author keywords

Diabetes mellitus; Mitochondria; Nox 4; Physical activity

Indexed keywords

CALCIUM; HYDROGEN PEROXIDE; INSULIN; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; NOX4 PROTEIN, RAT; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE;

EID: 84937874886     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00915.2014     Document Type: Article
Times cited : (22)

References (49)
  • 1
    • 77951281040 scopus 로고    scopus 로고
    • Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes
    • Ago T, Kuroda J, Pain J, Fu C, Li H, Sadoshima J. Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ Res 106: 1253-1264, 2010.
    • (2010) Circ Res , vol.106 , pp. 1253-1264
    • Ago, T.1    Kuroda, J.2    Pain, J.3    Fu, C.4    Li, H.5    Sadoshima, J.6
  • 5
    • 43549098268 scopus 로고    scopus 로고
    • Calcium cycling and signaling in cardiac myocytes
    • Bers DM. Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol 70: 23-49, 2008.
    • (2008) Annu Rev Physiol , vol.70 , pp. 23-49
    • Bers, D.M.1
  • 6
    • 0035206798 scopus 로고    scopus 로고
    • Ryanodine receptor dysfunction in hearts of streptozotocin-induced diabetic rats
    • Bidasee KR, Dinçer UD, Besch HR Jr. Ryanodine receptor dysfunction in hearts of streptozotocin-induced diabetic rats. Mol Pharmacol 60: 1356-1364, 2001.
    • (2001) Mol Pharmacol , vol.60 , pp. 1356-1364
    • Bidasee, K.R.1    Dinçer, U.D.2    Besch, H.R.3
  • 7
    • 34548848059 scopus 로고    scopus 로고
    • Mitochondrial energetics in the heart in obesity-related diabetes: Direct evidence for increased uncoupled respiration and activation of uncoupling proteins
    • Boudina S, Sena S, Theobald H, Sheng X, Wright JJ, Hu XX, Aziz S, Johnson JI, Bugger H, Zaha VG, Abel ED. Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 56: 2457-2466, 2007.
    • (2007) Diabetes , vol.56 , pp. 2457-2466
    • Boudina, S.1    Sena, S.2    Theobald, H.3    Sheng, X.4    Wright, J.J.5    Hu, X.X.6    Aziz, S.7    Johnson, J.I.8    Bugger, H.9    Zaha, V.G.10    Abel, E.D.11
  • 8
    • 77956572071 scopus 로고    scopus 로고
    • Mitochondria in the diabetic heart
    • Bugger H, Abel ED. Mitochondria in the diabetic heart. Cardiovasc Res 88: 229-240, 2010.
    • (2010) Cardiovasc Res , vol.88 , pp. 229-240
    • Bugger, H.1    Abel, E.D.2
  • 11
    • 0035209426 scopus 로고    scopus 로고
    • Echocardiographic characterization of fundamental mechanisms of abnormal diastolic filling in diabetic rats with a parameterized diastolic filling formalism
    • Dent CL, Bowman AW, Scott MJ, Allen JS, Lisauskas JB, Janif M, Wickline SA, Kovács SJ. Echocardiographic characterization of fundamental mechanisms of abnormal diastolic filling in diabetic rats with a parameterized diastolic filling formalism. J Am Soc Echocardiogr 14: 1166-1172, 2001.
    • (2001) J Am Soc Echocardiogr , vol.14 , pp. 1166-1172
    • Dent, C.L.1    Bowman, A.W.2    Scott, M.J.3    Allen, J.S.4    Lisauskas, J.B.5    Janif, M.6    Wickline, S.A.7    Kovács, S.J.8
  • 12
    • 4143140134 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Evidence, mechanisms, and therapeutic implications
    • Fang ZY, Prins JB, Marwick TH. Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications. Endocr Rev 25: 543-567, 2004.
    • (2004) Endocr Rev , vol.25 , pp. 543-567
    • Fang, Z.Y.1    Prins, J.B.2    Marwick, T.H.3
  • 16
    • 0033837124 scopus 로고    scopus 로고
    • Diminished function and expression of the cardiac Na+-Ca2+ exchanger in diabetic rats: Implication in Ca2+ overload
    • Hattori Y, Matsuda N, Kimura J, Ishitani T, Tamada A, Gando S, Kemmotsu O, Kanno M. Diminished function and expression of the cardiac Na+-Ca2+ exchanger in diabetic rats: implication in Ca2+ overload. J Physiol 527: 85-94, 2000.
    • (2000) J Physiol , vol.527 , pp. 85-94
    • Hattori, Y.1    Matsuda, N.2    Kimura, J.3    Ishitani, T.4    Tamada, A.5    Gando, S.6    Kemmotsu, O.7    Kanno, M.8
  • 17
    • 84903141088 scopus 로고    scopus 로고
    • Exercise preconditioning-induced early and late phase of cardioprotection is associated with protein kinase C epsilon translocation
    • Hao Z, Pan SS, Shen YJ, Ge J. Exercise preconditioning-induced early and late phase of cardioprotection is associated with protein kinase C epsilon translocation. Circ J 78: 1636-1645, 2014.
    • (2014) Circ J , vol.78 , pp. 1636-1645
    • Hao, Z.1    Pan, S.S.2    Shen, Y.J.3    Ge, J.4
  • 18
    • 58149458130 scopus 로고    scopus 로고
    • Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats
    • Herlein JA, Fink BD, O'Malley Y, Sivitz WI. Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats. Endocrinology 150: 46-55, 2009.
    • (2009) Endocrinology , vol.150 , pp. 46-55
    • Herlein, J.A.1    Fink, B.D.2    O'Malley, Y.3    Sivitz, W.I.4
  • 19
    • 0033009885 scopus 로고    scopus 로고
    • Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart
    • Hidaka S, Kakuma T, Yoshimatsu H, Sakino H, Fukuchi S, Sakata T. Streptozotocin treatment upregulates uncoupling protein 3 expression in the rat heart. Diabetes 48: 430-435, 1999.
    • (1999) Diabetes , vol.48 , pp. 430-435
    • Hidaka, S.1    Kakuma, T.2    Yoshimatsu, H.3    Sakino, H.4    Fukuchi, S.5    Sakata, T.6
  • 20
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin PJ, Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 74: 214-226, 1976.
    • (1976) Anal Biochem , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 21
    • 33645037187 scopus 로고    scopus 로고
    • Effects of insulin treatment on heart rhythm, body temperature and physical activity in streptozotocin-induced diabetic rat
    • Howarth FC, Jacobson M, Shafiullah M, Adeghate E. Effects of insulin treatment on heart rhythm, body temperature and physical activity in streptozotocin-induced diabetic rat. Clin Exp Pharmacol Physiol 33: 327-331, 2006.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 327-331
    • Howarth, F.C.1    Jacobson, M.2    Shafiullah, M.3    Adeghate, E.4
  • 22
    • 0003077616 scopus 로고    scopus 로고
    • Exercise and diet modulate cardiac lipid peroxidation and antioxidant defenses
    • Kim JD, Yu BP, McCarter RJ, Lee SY, Herlihy JT. Exercise and diet modulate cardiac lipid peroxidation and antioxidant defenses. Free Radic Biol Med 20: 283-288, 1996.
    • (1996) Free Radic Biol Med , vol.20 , pp. 283-288
    • Kim, J.D.1    Yu, B.P.2    McCarter, R.J.3    Lee, S.Y.4    Herlihy, J.T.5
  • 25
    • 0015320148 scopus 로고
    • The positive inotropic action of insulin in the canine heart
    • Lucchesi BR, Medina M, Kniffen FJ. The positive inotropic action of insulin in the canine heart. Eur J Pharmacol 18: 107-115, 1972.
    • (1972) Eur J Pharmacol , vol.18 , pp. 107-115
    • Lucchesi, B.R.1    Medina, M.2    Kniffen, F.J.3
  • 26
    • 78650035561 scopus 로고    scopus 로고
    • Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia
    • Lumini-Oliveira J, Magalhaes J, Pereira CV, Moreira AC, Oliveira PJ, Ascensao A. Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia. Mitochondrion 11: 54-63, 2010.
    • (2010) Mitochondrion , vol.11 , pp. 54-63
    • Lumini-Oliveira, J.1    Magalhaes, J.2    Pereira, C.V.3    Moreira, A.C.4    Oliveira, P.J.5    Ascensao, A.6
  • 28
    • 0037707713 scopus 로고    scopus 로고
    • Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats
    • Maritim AC, Sanders RA, Watkins JB. Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. J Nutr Biochem 14: 288-294, 2003.
    • (2003) J Nutr Biochem , vol.14 , pp. 288-294
    • Maritim, A.C.1    Sanders, R.A.2    Watkins, J.B.3
  • 29
    • 0033837124 scopus 로고    scopus 로고
    • Diminished function and expression of the cardiac Na+-Ca2+ exchanger in diabetic rats: Implication in Ca2+ overload
    • Matsuda N, Hattori Y, Kimura J, Ishitani T, Tamada A, Gando S, Kemmotsu O, Kanno M. Diminished function and expression of the cardiac Na+-Ca2+ exchanger in diabetic rats: implication in Ca2+ overload. J Physiol 527: 85-94, 2000.
    • (2000) J Physiol , vol.527 , pp. 85-94
    • Matsuda, N.1    Hattori, Y.2    Kimura, J.3    Ishitani, T.4    Tamada, A.5    Gando, S.6    Kemmotsu, O.7    Kanno, M.8
  • 34
    • 0021936228 scopus 로고
    • Modification of the function of cardiac subcellular organelles by insulin
    • Pierce GN, Ganguly PK, Dzurba A, Dhalla NS. Modification of the function of cardiac subcellular organelles by insulin. Adv Myocardiol 6: 113-125, 1985.
    • (1985) Adv Myocardiol , vol.6 , pp. 113-125
    • Pierce, G.N.1    Ganguly, P.K.2    Dzurba, A.3    Dhalla, N.S.4
  • 36
    • 0027364206 scopus 로고
    • Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain neurons
    • Rajdev S, Reynolds IJ. Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain neurons. Neurosci Lett 162: 149-152, 1993.
    • (1993) Neurosci Lett , vol.162 , pp. 149-152
    • Rajdev, S.1    Reynolds, I.J.2
  • 37
    • 0020511493 scopus 로고
    • Effect of insulin replacement on streptozotocin-induced effects in the rat heart
    • Ramanadham S, Decker P, Tenner TE. Effect of insulin replacement on streptozotocin-induced effects in the rat heart. Life Sci 33: 289-296, 1983.
    • (1983) Life Sci , vol.33 , pp. 289-296
    • Ramanadham, S.1    Decker, P.2    Tenner, T.E.3
  • 39
    • 0028239163 scopus 로고
    • Oxidative damage to proteins: Spectrophotometric method for the carbonyl assay
    • Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for the carbonyl assay. Methods Enzymol 233: 357-363, 1994.
    • (1994) Methods Enzymol , vol.233 , pp. 357-363
    • Reznick, A.Z.1    Packer, L.2
  • 40
    • 0022979484 scopus 로고
    • Heart mitochondria in physiological salt solution: Not ionic strength but salt composition is important for association of creatine kinase with the inner membrane surface
    • Saks VA, Khuchua ZA, Kuznetsov AV, Veksler VI, Sharov VG. Heart mitochondria in physiological salt solution: not ionic strength but salt composition is important for association of creatine kinase with the inner membrane surface. Biochem Biophys Res Commun 139: 1262-1271, 1986.
    • (1986) Biochem Biophys Res Commun , vol.139 , pp. 1262-1271
    • Saks, V.A.1    Khuchua, Z.A.2    Kuznetsov, A.V.3    Veksler, V.I.4    Sharov, V.G.5
  • 42
    • 0032564864 scopus 로고    scopus 로고
    • Uncoupling: New approaches to an old problem of bioenergetics
    • Skulachev VP. Uncoupling: new approaches to an old problem of bioenergetics. Biochim Biophys Acta 1363: 100-124, 1998.
    • (1998) Biochim Biophys Acta , vol.1363 , pp. 100-124
    • Skulachev, V.P.1
  • 43
    • 0033837635 scopus 로고    scopus 로고
    • Diminished expression of sarcoplasmic reticulum Ca2+-ATPase and ryanodine sensitive Ca2+ Channel mRNA in streptozotocininduced diabetic rat heart
    • Teshima Y, Takahashi N, Saikawa T, Hara M, Yasunaga S, Hidaka S, Sakata T. Diminished expression of sarcoplasmic reticulum Ca2+-ATPase and ryanodine sensitive Ca2+ Channel mRNA in streptozotocininduced diabetic rat heart. J Mol Cell Cardiol 32: 655-664, 2000.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 655-664
    • Teshima, Y.1    Takahashi, N.2    Saikawa, T.3    Hara, M.4    Yasunaga, S.5    Hidaka, S.6    Sakata, T.7
  • 46
    • 40849094267 scopus 로고    scopus 로고
    • Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity
    • Winnick JJ, Sherman WM, Habash DL, Stout MB, Failla ML, Belury MA, Schuster DP. Short-term aerobic exercise training in obese humans with type 2 diabetes mellitus improves whole-body insulin sensitivity through gains in peripheral, not hepatic insulin sensitivity. J Clin Endocrinol Metab 93: 771-778, 2008.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 771-778
    • Winnick, J.J.1    Sherman, W.M.2    Habash, D.L.3    Stout, M.B.4    Failla, M.L.5    Belury, M.A.6    Schuster, D.P.7
  • 47
    • 46749156297 scopus 로고    scopus 로고
    • Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
    • Yu T, Sheu SS, Robotham JL, Yoon Y. Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species. Cardiovasc Res 79: 341-351, 2008.
    • (2008) Cardiovasc Res , vol.79 , pp. 341-351
    • Yu, T.1    Sheu, S.S.2    Robotham, J.L.3    Yoon, Y.4
  • 48
    • 33746308986 scopus 로고    scopus 로고
    • Decreased cardiac sarcoplasmic reticulum Ca2+-ATPase activity contributes to cardiac dysfunction in streptozotocin-induced diabetic rats
    • Zhao XY, Hu SJ, Li J, Mou Y, Chen BP, Xia Q. Decreased cardiac sarcoplasmic reticulum Ca2+-ATPase activity contributes to cardiac dysfunction in streptozotocin-induced diabetic rats. J Physiol Biochem 62: 1-8, 2006.
    • (2006) J Physiol Biochem , vol.62 , pp. 1-8
    • Zhao, X.Y.1    Hu, S.J.2    Li, J.3    Mou, Y.4    Chen, B.P.5    Xia, Q.6
  • 49
    • 0031573401 scopus 로고    scopus 로고
    • A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases
    • Zhou M, Diwu Z, Panchuk-Voloshina N, Haugland RP. A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. Anal Biochem 15: 162-168, 2007.
    • (2007) Anal Biochem , vol.15 , pp. 162-168
    • Zhou, M.1    Diwu, Z.2    Panchuk-Voloshina, N.3    Haugland, R.P.4


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