메뉴 건너뛰기




Volumn 33, Issue 5, 2015, Pages 320-325

Knockdown of NF-κB p65 subunit expression suppresses growth of nude mouse lung tumour cell xenografts by inhibition of Bcl-2 apoptotic pathway

Author keywords

Apoptosis; Lung cancer; NF B; Small interfering RNA; Xenografts

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; MESSENGER RNA; PROTEIN BCL 2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; BCLAF1 PROTEIN, MOUSE; REPRESSOR PROTEIN;

EID: 84937807474     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.3117     Document Type: Article
Times cited : (15)

References (35)
  • 1
  • 2
    • 84873353426 scopus 로고    scopus 로고
    • Induction of apoptosis in A431 skin cancer cells by Cissusquadrangularis Linn stem extract by altering Bax-Bcl-2 ratio, release of cytochrome c from mitochondria and PARP cleavage
    • Bhujade A, Gupta G, Talmale S, Das S, Patil M. Induction of apoptosis in A431 skin cancer cells by Cissusquadrangularis Linn stem extract by altering Bax-Bcl-2 ratio, release of cytochrome c from mitochondria and PARP cleavage. Food funct 2013; 4: 338-346.
    • (2013) Food funct , vol.4 , pp. 338-346
    • Bhujade, A.1    Gupta, G.2    Talmale, S.3    Das, S.4    Patil, M.5
  • 3
    • 84876717496 scopus 로고    scopus 로고
    • Study of apoptosis in oral pemphigus vulgaris using immunohistochemical marker Bax and TUNEL technique
    • Deyhimi P, Tavakoli P. Study of apoptosis in oral pemphigus vulgaris using immunohistochemical marker Bax and TUNEL technique. J Oral Pathol Med 2012; 42: 409-414.
    • (2012) J Oral Pathol Med , vol.42 , pp. 409-414
    • Deyhimi, P.1    Tavakoli, P.2
  • 4
    • 84866745062 scopus 로고    scopus 로고
    • The role of adjuvant chemotherapy in early-stage and locally advanced non-small cell lung cancer
    • Shapiro M. The role of adjuvant chemotherapy in early-stage and locally advanced non-small cell lung cancer. Cleve Clin J Med 2012; 79: e-S42-e-S45.
    • (2012) Cleve Clin J Med , vol.79 , pp. S42-S45
    • Shapiro, M.1
  • 5
    • 84873676278 scopus 로고    scopus 로고
    • Update of research on drug resistance in small cell lung cancer chemotherapy
    • Chen Y-T, Feng B, Chen L-B. Update of research on drug resistance in small cell lung cancer chemotherapy. Asian Pac J Cancer Prev 2012; 13: 3577-3581.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 3577-3581
    • Chen, Y.-T.1    Feng, B.2    Chen, L.-B.3
  • 6
  • 7
    • 33847301497 scopus 로고    scopus 로고
    • Novel therapeutic targets in lung cancer: inhibitor of apoptosis proteins from laboratory to clinic
    • Dean EJ, Ranson M, Blackhall F, Holt SV, Dive C. Novel therapeutic targets in lung cancer: inhibitor of apoptosis proteins from laboratory to clinic. Cancer Treat Rev 2007; 33: 203-212.
    • (2007) Cancer Treat Rev , vol.33 , pp. 203-212
    • Dean, E.J.1    Ranson, M.2    Blackhall, F.3    Holt, S.V.4    Dive, C.5
  • 8
    • 0035989680 scopus 로고    scopus 로고
    • HSP90 as a new therapeutic target for cancer therapy: the story unfolds
    • Maloney A, Workman P. HSP90 as a new therapeutic target for cancer therapy: the story unfolds. Expert Opin Biol Ther 2002; 2: 3-24.
    • (2002) Expert Opin Biol Ther , vol.2 , pp. 3-24
    • Maloney, A.1    Workman, P.2
  • 10
    • 0037096221 scopus 로고    scopus 로고
    • NF-κB: arresting a major culprit in cancer
    • Haefner B. NF-κB: arresting a major culprit in cancer. Drug Discov Today 2002; 7: 653-663.
    • (2002) Drug Discov Today , vol.7 , pp. 653-663
    • Haefner, B.1
  • 11
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-kappaB transcription factors
    • Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene 1999; 18: 6910-6924.
    • (1999) Oncogene , vol.18 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.D.2
  • 12
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: from innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li Z-W. NF-κB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002; 2: 301-310.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.-W.4
  • 13
    • 0036009115 scopus 로고    scopus 로고
    • NF-κB at the crossroads of life and death
    • Karin M, Lin A. NF-κB at the crossroads of life and death. Nat Immunol 2002; 3: 221-227.
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 14
    • 0033532386 scopus 로고    scopus 로고
    • The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
    • Li Z-W, Chu W, Hu Y, et al. The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis. J Exp Med 1999; 189: 1839-1845.
    • (1999) J Exp Med , vol.189 , pp. 1839-1845
    • Li, Z.-W.1    Chu, W.2    Hu, Y.3
  • 15
    • 79951715041 scopus 로고    scopus 로고
    • Small interfering RNA for effective cancer therapies
    • Wang X, Chen Y, Ren J, Qu X. Small interfering RNA for effective cancer therapies. Mini Rev Med Chem 2011; 11: 114-124.
    • (2011) Mini Rev Med Chem , vol.11 , pp. 114-124
    • Wang, X.1    Chen, Y.2    Ren, J.3    Qu, X.4
  • 17
    • 37549033098 scopus 로고    scopus 로고
    • RNA aptamer-targeted inhibition of NF-κB suppresses non-small cell lung cancer resistance to doxorubicin
    • Mi J, Zhang X, Rabbani ZN, et al. RNA aptamer-targeted inhibition of NF-κB suppresses non-small cell lung cancer resistance to doxorubicin. Mol Ther 2007; 16: 66-73.
    • (2007) Mol Ther , vol.16 , pp. 66-73
    • Mi, J.1    Zhang, X.2    Rabbani, Z.N.3
  • 18
    • 27444431947 scopus 로고    scopus 로고
    • Expression of NF-kappa B and AP-1 in non-small cell lung cancer
    • Zhongguo fei ai za zhi= Chinese
    • Ma J, Zhang Z andZhang L. Expression of NF-kappa B and AP-1 in non-small cell lung cancer. Zhongguo fei ai za zhi= Chinese J lung cancer 2005; 8: 440.
    • (2005) J lung cancer , vol.8 , pp. 440
    • Ma, J.1    Zhang, Z.2    Zhang, L.3
  • 19
    • 0034502506 scopus 로고    scopus 로고
    • NF-κB activation in topoisomerase I inhibitor-induced apoptotic cell death in human non-small cell lung cancer
    • Tabata M, Ganapathi R. NF-κB activation in topoisomerase I inhibitor-induced apoptotic cell death in human non-small cell lung cancer. Ann N Y Acad Sci 2000; 922: 343-344.
    • (2000) Ann N Y Acad Sci , vol.922 , pp. 343-344
    • Tabata, M.1    Ganapathi, R.2
  • 20
    • 42149158906 scopus 로고    scopus 로고
    • Recent progress in the study of HIV-1 transcription factor NF-kappaB and its inhibitors
    • Yu M andLiu X. Recent progress in the study of HIV-1 transcription factor NF-kappaB and its inhibitors. Yao xue xue bao= Acta pharmace Sinica 2007; 42: 1007-1012.
    • (2007) Yao xue xue bao= Acta pharmace Sinica , vol.42 , pp. 1007-1012
    • Yu, M.1    Liu, X.2
  • 22
    • 0033392234 scopus 로고    scopus 로고
    • Death receptors, NF-kappa B activation and apoptosis: the potential for therapeutic intervention
    • Farrow S. Death receptors, NF-kappa B activation and apoptosis: the potential for therapeutic intervention. Biochem Soc Trans 1999; 27: 812.
    • (1999) Biochem Soc Trans , vol.27 , pp. 812
    • Farrow, S.1
  • 24
    • 77950819906 scopus 로고    scopus 로고
    • NF-κB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction
    • Rushworth SA, Bowles KM, Raninga P, MacEwan DJ. NF-κB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction. Cancer Res 2010; 70: 2973-2983.
    • (2010) Cancer Res , vol.70 , pp. 2973-2983
    • Rushworth, S.A.1    Bowles, K.M.2    Raninga, P.3    MacEwan, D.J.4
  • 25
    • 33845307265 scopus 로고    scopus 로고
    • Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-κB inactivation
    • Kim D-S, Park S-S, Nam B-H, Kim I-H, Kim S-Y. Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-κB inactivation. Cancer Res 2006; 66: 10936-10943.
    • (2006) Cancer Res , vol.66 , pp. 10936-10943
    • Kim, D.-S.1    Park, S.-S.2    Nam, B.-H.3    Kim, I.-H.4    Kim, S.-Y.5
  • 26
    • 70449109147 scopus 로고    scopus 로고
    • Requirement for NF-&kgr; B signalling in a mouse model of lung adenocarcinoma
    • Meylan E, Dooley AL, Feldser DM, et al. Requirement for NF-&kgr; B signalling in a mouse model of lung adenocarcinoma. Nature 2009; 462: 104-107.
    • (2009) Nature , vol.462 , pp. 104-107
    • Meylan, E.1    Dooley, A.L.2    Feldser, D.M.3
  • 27
    • 79953064635 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden
    • Connelly L, Barham W, Onishko HM, et al. Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden. Oncogene 2010; 30: 1402-1412.
    • (2010) Oncogene , vol.30 , pp. 1402-1412
    • Connelly, L.1    Barham, W.2    Onishko, H.M.3
  • 28
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 29
    • 84855773615 scopus 로고    scopus 로고
    • A small interfering RNA targeting NF-κB p65 alone or combined with 5-FU inhibits growth of esophageal squamous cell carcinoma in nude mice
    • Tian F, Fan T, Jiang Y, Zhang X, Wang X. A small interfering RNA targeting NF-κB p65 alone or combined with 5-FU inhibits growth of esophageal squamous cell carcinoma in nude mice. Pathol Res Pract 2012; 208: 32-38.
    • (2012) Pathol Res Pract , vol.208 , pp. 32-38
    • Tian, F.1    Fan, T.2    Jiang, Y.3    Zhang, X.4    Wang, X.5
  • 30
    • 57349161164 scopus 로고    scopus 로고
    • Intraperitoneal administration of a small interfering RNA targeting nuclear factor-kappa B with paclitaxel successfully prolongs the survival of xenograft model mice with peritoneal metastasis of gastric cancer
    • Inoue M, Matsumoto S, Saito H, Tsujitani S, Ikeguchi M. Intraperitoneal administration of a small interfering RNA targeting nuclear factor-kappa B with paclitaxel successfully prolongs the survival of xenograft model mice with peritoneal metastasis of gastric cancer. Int J Cancer 2008; 123: 2696-2701.
    • (2008) Int J Cancer , vol.123 , pp. 2696-2701
    • Inoue, M.1    Matsumoto, S.2    Saito, H.3    Tsujitani, S.4    Ikeguchi, M.5
  • 31
    • 84883497442 scopus 로고    scopus 로고
    • Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/Bcl-2 expression and activating caspase-3 pathway
    • Zhu A, Zhou H, Xia J, et al. Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/Bcl-2 expression and activating caspase-3 pathway. Braz J Med Biol Res 2013; 46: 670-675.
    • (2013) Braz J Med Biol Res , vol.46 , pp. 670-675
    • Zhu, A.1    Zhou, H.2    Xia, J.3
  • 32
    • 0035504081 scopus 로고    scopus 로고
    • Transcriptional regulation of Bcl-2 by nuclear factor kappa B and its significance in prostate cancer
    • Cat ZSD, Johnson JL. Transcriptional regulation of Bcl-2 by nuclear factor kappa B and its significance in prostate cancer. Oncogene 2001; 20(50): 7342-7351.
    • (2001) Oncogene , vol.20 , Issue.50 , pp. 7342-7351
    • Cat, Z.S.D.1    Johnson, J.L.2
  • 33
    • 0038103154 scopus 로고    scopus 로고
    • NF-kappa B2/p100 induces Bcl-2 expression [J]
    • Viatour P, Bentires-Alj M, Chariot A, et al. NF-kappa B2/p100 induces Bcl-2 expression [J]. Leukemia 2003; 17(7): 1349-1356.
    • (2003) Leukemia , vol.17 , Issue.7 , pp. 1349-1356
    • Viatour, P.1    Bentires-Alj, M.2    Chariot, A.3
  • 34
    • 12344306010 scopus 로고    scopus 로고
    • p21WAF1 modulates NF-kappa B signaling and induces anti-apoptotic protein Bcl-2 in Tax-expressing rat fibroblast
    • Akita K, Kawata S, Shimotohno K. p21WAF1 modulates NF-kappa B signaling and induces anti-apoptotic protein Bcl-2 in Tax-expressing rat fibroblast. Virology 2005; 332(1): 249-257.
    • (2005) Virology , vol.332 , Issue.1 , pp. 249-257
    • Akita, K.1    Kawata, S.2    Shimotohno, K.3
  • 35
    • 21244474683 scopus 로고    scopus 로고
    • Targeting Bcl-2 overexpression in various human malignancies through NF-kappa B inhibition by the proteasome inhibitor bortezomib[J]
    • Fahy BN, Schlieman MG, Mortenson MM, et al. Targeting Bcl-2 overexpression in various human malignancies through NF-kappa B inhibition by the proteasome inhibitor bortezomib[J]. Cancer Chemother Pharmacol 2005; 56(1): 46-54.
    • (2005) Cancer Chemother Pharmacol , vol.56 , Issue.1 , pp. 46-54
    • Fahy, B.N.1    Schlieman, M.G.2    Mortenson, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.