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Volumn 44, Issue 4, 2015, Pages 321-330

Effects of FGF-2 and FGF receptor antagonists on MMP enzymes, aggrecan, and type II collagen in primary human OA chondrocytes

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; AZD 4547; COLLAGEN TYPE 2; COLLAGENASE 3; FIBROBLAST GROWTH FACTOR 2; INFIGRATINIB; INTERSTITIAL COLLAGENASE; 3-(2,6-DICHLORO-3,5-DIMETHOXYPHENYL)-1-(6-(4-(4-ETHYLPIPERAZIN-1-YL)-PHENYLAMINO)PYRIMIDIN-4-YL)-1-METHYLUREA; BENZAMIDE DERIVATIVE; CARBANILAMIDE DERIVATIVE; FIBROBLAST GROWTH FACTOR RECEPTOR; MATRIX METALLOPROTEINASE; PIPERAZINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

EID: 84937793103     PISSN: 03009742     EISSN: 15027732     Source Type: Journal    
DOI: 10.3109/03009742.2014.1000372     Document Type: Article
Times cited : (50)

References (31)
  • 3
    • 20144378016 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis
    • Davidson D, Blanc A, Filion D, Wang H, Plut P, Pfeffer G, et al. Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis. J Biol Chem 2005;280:20509-15.
    • (2005) J Biol Chem , vol.280 , pp. 20509-20515
    • Davidson, D.1    Blanc, A.2    Filion, D.3    Wang, H.4    Plut, P.5    Pfeffer, G.6
  • 4
    • 20944443514 scopus 로고    scopus 로고
    • Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injuryinduced osteoarthritis
    • Moore EE, Bendele AM, Thompson DL, Littau A, Waggie KS, Reardon B, et al. Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injuryinduced osteoarthritis. Osteoarthritis Cartilage 2005;13:623-31.
    • (2005) Osteoarthritis Cartilage , vol.13 , pp. 623-631
    • Moore, E.E.1    Bendele, A.M.2    Thompson, D.L.3    Littau, A.4    Waggie, K.S.5    Reardon, B.6
  • 5
    • 33846214070 scopus 로고    scopus 로고
    • FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate
    • Liu Z, Lavine KJ, Hung IH, Ornitz DM. FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol 2007;302:80-91.
    • (2007) Dev Biol , vol.302 , pp. 80-91
    • Liu, Z.1    Lavine, K.J.2    Hung, I.H.3    Ornitz, D.M.4
  • 6
    • 84903455882 scopus 로고    scopus 로고
    • Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: A randomized, doubleblind, placebo-controlled trial
    • Lohmander LS,Hellot S, Dreher D, Krantz EF,Kruger DS, Guermazi A, et al. Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, doubleblind, placebo-controlled trial. Arthritis Rheum 2014; 66:1820-31.
    • (2014) Arthritis Rheum , vol.66 , pp. 1820-1831
    • Lohmander, L.S.1    Hellot, S.2    Dreher, D.3    Krantz, E.F.4    Kruger, D.S.5    Guermazi, A.6
  • 8
    • 29144507688 scopus 로고    scopus 로고
    • Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes
    • Loeser RF, Chubinskaya S, Pacione C, Im HJ. Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes. Arthritis Rheum 2005;52:3910-17.
    • (2005) Arthritis Rheum , vol.52 , pp. 3910-3917
    • Loeser, R.F.1    Chubinskaya, S.2    Pacione, C.3    Im, H.J.4
  • 9
    • 34249688522 scopus 로고    scopus 로고
    • Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogenactivated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes
    • Im HJ, Muddasani P, Natarajan V, Schmid TM, Block JA, Davis F, et al. Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogenactivated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes. J Biol Chem2007; 282:11110-1.
    • (2007) J Biol Chem , vol.282 , pp. 11110-11111
    • Im, H.J.1    Muddasani, P.2    Natarajan, V.3    Schmid, T.M.4    Block, J.A.5    Davis, F.6
  • 10
    • 35748961128 scopus 로고    scopus 로고
    • Basic fibroblast growth factor activates the MAPK and NFkappaB pathways that converge on Elk-1 to control production of matrix metalloproteinase-13 by human adult articular chondrocytes
    • Muddasani P, Norman JC, Ellman M, van Wijnen AJ, Im HJ. Basic fibroblast growth factor activates the MAPK and NFkappaB pathways that converge on Elk-1 to control production of matrix metalloproteinase-13 by human adult articular chondrocytes. J Biol Chem 2007;282:31409-21.
    • (2007) J Biol Chem , vol.282 , pp. 31409-31421
    • Muddasani, P.1    Norman, J.C.2    Ellman, M.3    Van Wijnen, A.J.4    Im, H.J.5
  • 11
    • 80051485778 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes
    • Yan D, Chen D, Cool SM, van Wijnen AJ, Mikecz K, Murphy G, et al. Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes. Arthritis Res Ther 2011;13:R130.
    • (2011) Arthritis Res Ther , vol.13 , pp. R130
    • Yan, D.1    Chen, D.2    Cool, S.M.3    Van Wijnen, A.J.4    Mikecz, K.5    Murphy, G.6
  • 12
    • 55849122274 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage
    • Sawaji Y, Hynes J, Vincent T, Saklatvala J. Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage. Arthritis Rheum 2008;58:3498-509.
    • (2008) Arthritis Rheum , vol.58 , pp. 3498-3509
    • Sawaji, Y.1    Hynes, J.2    Vincent, T.3    Saklatvala, J.4
  • 13
    • 67650034636 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis
    • Chia SL, Sawaji Y, Burleigh A, McLean C, Inglis J, Saklatvala J, et al. Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis. Arthritis Rheum 2009;60:2019-27.
    • (2009) Arthritis Rheum , vol.60 , pp. 2019-2027
    • Chia, S.L.1    Sawaji, Y.2    Burleigh, A.3    McLean, C.4    Inglis, J.5    Saklatvala, J.6
  • 14
    • 80053965851 scopus 로고    scopus 로고
    • Fibroblast growth factor 2: Good or bad guy in the joint?
    • Vincent TL. Fibroblast growth factor 2: good or bad guy in the joint? Arthritis Res Ther 2011;13:127.
    • (2011) Arthritis Res Ther , vol.13 , pp. 127
    • Vincent, T.L.1
  • 15
    • 84861016275 scopus 로고    scopus 로고
    • Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family
    • Li X, Ellman MB, Kroin JS, Chen D, Yan D, Mikecz K, et al. Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family. J Cell Biochem 2012;113:2532-42.
    • (2012) J Cell Biochem , vol.113 , pp. 2532-2542
    • Li, X.1    Ellman, M.B.2    Kroin, J.S.3    Chen, D.4    Yan, D.5    Mikecz, K.6
  • 16
    • 78650982530 scopus 로고    scopus 로고
    • The role of the cartilage matrix in osteoarthritis
    • Heinegard D, Saxne T. The role of the cartilage matrix in osteoarthritis. Nat Rev Rheumatol 2011;7:50-6.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 50-56
    • Heinegard, D.1    Saxne, T.2
  • 18
    • 0036240838 scopus 로고    scopus 로고
    • Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene-specific transcription factors
    • Vincenti MP, Brinckerhoff CE. Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors. Arthritis Res 2002;4:157-64.
    • (2002) Arthritis Res , vol.4 , pp. 157-164
    • Vincenti, M.P.1    Brinckerhoff, C.E.2
  • 19
    • 0035677833 scopus 로고    scopus 로고
    • Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology
    • Aigner T, Zien A, Gehrsitz A, Gebhard PM, McKenna L. Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology. Arthritis Rheum 2001;44:2777-89.
    • (2001) Arthritis Rheum , vol.44 , pp. 2777-2789
    • Aigner, T.1    Zien, A.2    Gehrsitz, A.3    Gebhard, P.M.4    McKenna, L.5
  • 20
    • 0036822797 scopus 로고    scopus 로고
    • Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
    • Bau B, Gebhard PM, Haag J, Knorr T, Bartnik E, Aigner T. Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro. Arthritis Rheum 2002;46:2648-57.
    • (2002) Arthritis Rheum , vol.46 , pp. 2648-2657
    • Bau, B.1    Gebhard, P.M.2    Haag, J.3    Knorr, T.4    Bartnik, E.5    Aigner, T.6
  • 21
    • 84863777207 scopus 로고    scopus 로고
    • Correlation between plasma and synovial fluid basic fibroblast growth factor with radiographic severity in primary knee osteoarthritis
    • Honsawek S, Yuktanandana P, Tanavalee A, Saetan N, Anomasiri W, Parkpian V. Correlation between plasma and synovial fluid basic fibroblast growth factor with radiographic severity in primary knee osteoarthritis. Int Orthop 2012;36:981-5.
    • (2012) Int Orthop , vol.36 , pp. 981-985
    • Honsawek, S.1    Yuktanandana, P.2    Tanavalee, A.3    Saetan, N.4    Anomasiri, W.5    Parkpian, V.6
  • 22
    • 84870308824 scopus 로고    scopus 로고
    • Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice
    • Weng T, Yi L, Huang J, Luo F, Wen X, Du X, et al. Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice. Arthritis Rheum 2012;64:3982-92.
    • (2012) Arthritis Rheum , vol.64 , pp. 3982-3992
    • Weng, T.1    Yi, L.2    Huang, J.3    Luo, F.4    Wen, X.5    Du, X.6
  • 23
    • 0022465236 scopus 로고
    • Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and therapeutic criteria committee of the American rheumatism association
    • Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986;29:1039-49.
    • (1986) Arthritis Rheum , vol.29 , pp. 1039-1049
    • Altman, R.1    Asch, E.2    Bloch, D.3    Bole, G.4    Borenstein, D.5    Brandt, K.6
  • 24
    • 79955654715 scopus 로고    scopus 로고
    • Leptin enhancesMMP-1,MMP-3 andMMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid fromOApatients
    • Koskinen A, Vuolteenaho K, Nieminen R, Moilanen T,Moilanen E. Leptin enhancesMMP-1,MMP-3 andMMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid fromOApatients. Clin Exp Rheumatol 2011;29:57-64.
    • (2011) Clin Exp Rheumatol , vol.29 , pp. 57-64
    • Koskinen, A.1    Vuolteenaho, K.2    Nieminen, R.3    Moilanen, T.4    Moilanen, E.5
  • 25
    • 81055126964 scopus 로고    scopus 로고
    • Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways
    • Koskinen A, Juslin S, Nieminen R, Moilanen T, Vuolteenaho K, Moilanen E. Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways. Arthritis Res Ther 2011;13:R184.
    • (2011) Arthritis Res Ther , vol.13 , pp. R184
    • Koskinen, A.1    Juslin, S.2    Nieminen, R.3    Moilanen, T.4    Vuolteenaho, K.5    Moilanen, E.6
  • 26
    • 84860120185 scopus 로고    scopus 로고
    • AZD4547: An orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family
    • Gavine PR, Mooney L, Kilgour E, Thomas AP, Al-Kadhimi K, Beck S, et al. AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res 2012;72:2045-56.
    • (2012) Cancer Res , vol.72 , pp. 2045-2056
    • Gavine, P.R.1    Mooney, L.2    Kilgour, E.3    Thomas, A.P.4    Al-Kadhimi, K.5    Beck, S.6
  • 27
    • 80054900437 scopus 로고    scopus 로고
    • Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methylurea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase
    • Guagnano V, Furet P, Spanka C, Bordas V, Le Douget M, Stamm C, et al. Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methylurea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. J Med Chem 2011;54:7066-83.
    • (2011) J Med Chem , vol.54 , pp. 7066-7083
    • Guagnano, V.1    Furet, P.2    Spanka, C.3    Bordas, V.4    Le Douget, M.5    Stamm, C.6
  • 28
    • 84880276188 scopus 로고    scopus 로고
    • Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated byMAPKphosphatase-1
    • Korhonen R, Hommo T, Keranen T, Laavola M, Hamalainen M, Vuolteenaho K, et al. Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated byMAPKphosphatase-1. Br J Pharmacol 2013;169:1525-36.
    • (2013) Br J Pharmacol , vol.169 , pp. 1525-1536
    • Korhonen, R.1    Hommo, T.2    Keranen, T.3    Laavola, M.4    Hamalainen, M.5    Vuolteenaho, K.6
  • 30
    • 58149123407 scopus 로고    scopus 로고
    • Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes
    • Wang X, Song Y, Jacobi JL, Tuan RS. Inhibition of histone deacetylases antagonized FGF2 and IL-1beta effects on MMP expression in human articular chondrocytes. Growth Factors 2009;27:40-9.
    • (2009) Growth Factors , vol.27 , pp. 40-49
    • Wang, X.1    Song, Y.2    Jacobi, J.L.3    Tuan, R.S.4
  • 31
    • 34249987876 scopus 로고    scopus 로고
    • FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer
    • Vincent TL, McLean CJ, Full LE, Peston D, Saklatvala J. FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer. Osteoarthritis Cartilage 2007;15:752-63.
    • (2007) Osteoarthritis Cartilage , vol.15 , pp. 752-763
    • Vincent, T.L.1    McLean, C.J.2    Full, L.E.3    Peston, D.4    Saklatvala, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.