Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

PLoS Genetics

Volumn 11, Issue 6, 2015, Pages

  Sengle, Gerhard ^a,b,d   Carlberg, Valerie ^a,b   Tufa, Sara F ^b   Charbonneau, Noe L ^b   Smaldone, Silvia ^c   Carlson, Eric J ^b   Ramirez, Francesco ^c   Keene, Douglas R ^b   Sakai, Lynn Y ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b SHRINERS HOSPITAL FOR CHILDREN   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBRILLIN 2; NOGGIN; OSTEOGENIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; ACTIN BINDING PROTEIN; BMP7 PROTEIN, MOUSE; CREATINE KINASE; FBN1 PROTEIN, MOUSE; FBN2 PROTEIN, MOUSE; FIBRILLIN; FIBRILLIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHROGRYPOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FBN2 GENE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY; HOMOZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; LIPID STORAGE; MICRO-COMPUTED TOMOGRAPHY; MORPHOLOGY; MOUSE; MUSCLE MASS; MUSCULAR DYSTROPHY; MUTAGENESIS; MYOPATHY; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ABNORMALITIES; ANIMAL; BLOOD; C57BL MOUSE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LIMB MALFORMATION; MALE; METABOLISM; MUSCLE DISEASE; MUTANT MOUSE STRAIN; NEWBORN; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; SKELETAL MUSCLE;

MUS;

ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEIN 7; BONE MORPHOGENETIC PROTEINS; CREATINE KINASE; FEMALE; FIBRILLIN-1; FIBRILLIN-2; FIBRILLINS; GENE EXPRESSION REGULATION; LIMB DEFORMITIES, CONGENITAL; MALE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROFILAMENT PROTEINS; MUSCLE, SKELETAL; MUSCULAR DISEASES; MUSCULAR DYSTROPHIES; ORGAN CULTURE TECHNIQUES; SIGNAL TRANSDUCTION;

EID: 84937791785     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005340     Document Type: Article

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