-
1
-
-
84903379469
-
Trends in hypersensitivity drug reactions: More drugs, more response patterns, more heterogeneity
-
quiz 1 p following 53
-
Dona I, Barrionuevo E, Blanca-Lopez N, et al. Trends in hypersensitivity drug reactions: more drugs, more response patterns, more heterogeneity. J Investig Allergol Clin Immunol 2014; 24: 143-153; quiz 1 p following 53
-
(2014)
J Investig Allergol Clin Immunol
, vol.24
, pp. 143-153
-
-
Dona, I.1
Barrionuevo, E.2
Blanca-Lopez, N.3
-
3
-
-
77954938802
-
Definitions and mechanisms of drug hypersensitivity
-
Wedi B. Definitions and mechanisms of drug hypersensitivity. Expert Rev Clin Pharmacol 2010; 3: 539-551
-
(2010)
Expert Rev Clin Pharmacol
, vol.3
, pp. 539-551
-
-
Wedi, B.1
-
4
-
-
84900854522
-
Incorporation of pharmacogenomics into routine clinical practice: The clinical pharmacogenetics implementation consortium (cpic) guideline development process
-
Caudle KE, Klein TE, Hoffman JM, et al. Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr Drug Metab 2014; 15: 209-217
-
(2014)
Curr Drug Metab
, vol.15
, pp. 209-217
-
-
Caudle, K.E.1
Klein, T.E.2
Hoffman, J.M.3
-
5
-
-
0029068773
-
Heterogeneous t cell responses to beta-lactam-modified self-structures are observed in penicillinallergic individuals
-
Brander C, Mauri-Hellweg D, Bettens F, et al. Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillinallergic individuals. J Immunol 1995; 155: 2670-2678
-
(1995)
J Immunol
, vol.155
, pp. 2670-2678
-
-
Brander, C.1
Mauri-Hellweg, D.2
Bettens, F.3
-
6
-
-
33645766933
-
Pharmacological interaction of drugs with immune receptors: The p-i concept
-
Pichler WJ, Beeler A, Keller M, et al. Pharmacological interaction of drugs with immune receptors: the p-i concept. Allergol Int 2006; 55: 17-25
-
(2006)
Allergol Int
, vol.55
, pp. 17-25
-
-
Pichler, W.J.1
Beeler, A.2
Keller, M.3
-
8
-
-
79956333428
-
The phenotype standardization project: Improving pharmacogenetic studies of serious adverse drug reactions
-
Pirmohamed M, Aithal GP, Behr E, et al. The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions. Clin Pharmacol Ther 2011; 89: 784-785
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 784-785
-
-
Pirmohamed, M.1
Aithal, G.P.2
Behr, E.3
-
9
-
-
42549133224
-
Cytokine and chemokine expression in the skin from patients with maculopapular exanthema to drugs
-
Fernandez TD, Mayorga C, Torres MJ, et al. Cytokine and chemokine expression in the skin from patients with maculopapular exanthema to drugs. Allergy 2008; 63: 712-719
-
(2008)
Allergy
, vol.63
, pp. 712-719
-
-
Fernandez, T.D.1
Mayorga, C.2
Torres, M.J.3
-
11
-
-
33646198860
-
Pharmaco-metabonomic phenotyping and personalized drug treatment
-
Clayton TA, Lindon JC, Cloarec O, et al. Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature 2006; 440: 1073-1077
-
(2006)
Nature
, vol.440
, pp. 1073-1077
-
-
Clayton, T.A.1
Lindon, J.C.2
Cloarec, O.3
-
13
-
-
67649416267
-
Genetically based impairment in cyp2c8-And cyp2c9-dependent nsaid metabolism as a risk factor for gastrointestinal bleeding: Is a combination of pharmacogenomics and metabolomics required to improve personalized medicine
-
Agundez JA, Garcia-Martin E, Martinez C. Genetically based impairment in CYP2C8-And CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine? Expert Opin Drug Metab Toxicol 2009; 5: 607-620
-
(2009)
Expert Opin Drug Metab Toxicol
, vol.5
, pp. 607-620
-
-
Agundez, J.A.1
Garcia-Martin, E.2
Martinez, C.3
-
14
-
-
77952783359
-
Recent advances in drug intolerance
-
Agundez JA. Recent advances in drug intolerance. Curr Drug Metab 2009; 10: 946
-
(2009)
Curr Drug Metab
, vol.10
, pp. 946
-
-
Agundez, J.A.1
-
16
-
-
84876675474
-
Degradation of paracetamol by pure bacterial cultures and their microbial consortium
-
Zhang L, Hu J, Zhu R, et al. Degradation of paracetamol by pure bacterial cultures and their microbial consortium. Appl Microbiol Biotechnol 2013; 97: 3687-3698
-
(2013)
Appl Microbiol Biotechnol
, vol.97
, pp. 3687-3698
-
-
Zhang, L.1
Hu, J.2
Zhu, R.3
-
17
-
-
84893763297
-
Pharmacometabolomics: Implications for clinical pharmacology and systems pharmacology
-
Pharmacometabolomics Research Network
-
Kaddurah-Daouk R, Weinshilboum RM; Pharmacometabolomics Research Network. Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. Clin Pharmacol Ther 2014; 95: 154-167
-
(2014)
Clin Pharmacol Ther
, vol.95
, pp. 154-167
-
-
Kaddurah-Daouk, R.1
Weinshilboum, R.M.2
-
18
-
-
70149092771
-
Drugs, bugs, and personalized medicine: Pharmacometabonomics enters the ring
-
Wilson ID. Drugs, bugs, and personalized medicine: pharmacometabonomics enters the ring. Proc Natl Acad Sci U S A 2009; 106: 14187-14188
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14187-14188
-
-
Wilson, I.D.1
-
19
-
-
70149096873
-
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
-
Clayton TA, Baker D, Lindon JC, et al. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proc Natl Acad Sci U S A 2009; 106: 14728-14733
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14728-14733
-
-
Clayton, T.A.1
Baker, D.2
Lindon, J.C.3
-
21
-
-
77953673958
-
The complex clinical picture of beta-lactam hypersensitivity: Penicillins, cephalosporins, monobactams, carbapenems, and clavams
-
xii
-
Torres MJ, Blanca M. The complex clinical picture of beta-lactam hypersensitivity: penicillins, cephalosporins, monobactams, carbapenems, and clavams. Med Clin North Am 2010; 94: 805-820; xii
-
(2010)
Med Clin North Am
, vol.94
, pp. 805-820
-
-
Torres, M.J.1
Blanca, M.2
-
23
-
-
79957523368
-
Susceptibility to amoxicillin-clavulanateinduced liver injury is influenced by multiple HLA class i and II alleles
-
Lucena MI, Molokhia M, Shen Y, et al. Susceptibility to amoxicillin-clavulanateinduced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology 2011; 141: 338-347
-
(2011)
Gastroenterology
, vol.141
, pp. 338-347
-
-
Lucena, M.I.1
Molokhia, M.2
Shen, Y.3
-
24
-
-
84879990042
-
HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity
-
Stephens C, Lopez-Nevot MA, Ruiz-Cabello F, et al. HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity. PloS One 2013; 8: e68111
-
(2013)
PloS One
, vol.8
, pp. e68111
-
-
Stephens, C.1
Lopez-Nevot, M.A.2
Ruiz-Cabello, F.3
-
25
-
-
84920469747
-
HLA-dra variants predict penicillin allergy in genome-wide fine-mapping genotyping
-
Gueant JL, Romano A, Cornejo-Garcia JA, et al. HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping. J Allergy Clin Immunol 2015; 135: 253-259
-
(2015)
J Allergy Clin Immunol
, vol.135
, pp. 253-259
-
-
Gueant, J.L.1
Romano, A.2
Cornejo-Garcia, J.A.3
-
26
-
-
84918526640
-
Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: Ex vivo studies
-
Garzon D, Ariza A, Regazzoni L, et al. Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: ex vivo studies. Chem Res Toxicol 2014; 27: 1566-1574
-
(2014)
Chem Res Toxicol
, vol.27
, pp. 1566-1574
-
-
Garzon, D.1
Ariza, A.2
Regazzoni, L.3
-
27
-
-
84896935052
-
Study of protein haptenation by amoxicillin through the use of a biotinylated antibiotic
-
Ariza A, Collado D, Vida Y, et al. Study of protein haptenation by amoxicillin through the use of a biotinylated antibiotic. PloS One 2014; 9: e90891
-
(2014)
PloS One
, vol.9
, pp. e90891
-
-
Ariza, A.1
Collado, D.2
Vida, Y.3
-
28
-
-
84882614388
-
Metabolomic assays of amoxicillin, cephapirin and ceftiofur in chicken muscle: Application to treated chicken samples by liquid chromatography quadrupole time-of-flight mass spectrometry
-
Hermo MP, Gomez-Rodriguez P, Barbosa J, Barron D. Metabolomic assays of amoxicillin, cephapirin and ceftiofur in chicken muscle: application to treated chicken samples by liquid chromatography quadrupole time-of-flight mass spectrometry. J Pharm Biomed Anal 2013; 85: 169-178
-
(2013)
J Pharm Biomed Anal
, vol.85
, pp. 169-178
-
-
Hermo, M.P.1
Gomez-Rodriguez, P.2
Barbosa, J.3
Barron, D.4
-
29
-
-
84905028804
-
Identification of in vitro metabolites of amoxicillin in human liver microsomes by lc-esi/ms
-
Szultka M, Krzeminski R, Jackowski M, Buszewski B. Identification of in vitro metabolites of amoxicillin in human liver microsomes by LC-ESI/MS. Chromatographia 2014; 77: 1027-1035
-
(2014)
Chromatographia
, vol.77
, pp. 1027-1035
-
-
Szultka, M.1
Krzeminski, R.2
Jackowski, M.3
Buszewski, B.4
-
30
-
-
84908181204
-
High resolution mass spectrometry in the identification of transformation products and metabolites from beta-lactam antibiotics in thermally treated milk
-
Junza A, Montane A, Barbosa J, et al. High resolution mass spectrometry in the identification of transformation products and metabolites from beta-lactam antibiotics in thermally treated milk. J Chromatogr A 2014; 1368: 89-99
-
(2014)
J Chromatogr A
, vol.1368
, pp. 89-99
-
-
Junza, A.1
Montane, A.2
Barbosa, J.3
-
31
-
-
0029988737
-
Anaphylaxis to penicillins after nontherapeutic exposure: An immunological investigation
-
Blanca M, Garcia J, Vega JM, et al. Anaphylaxis to penicillins after nontherapeutic exposure: an immunological investigation. Clin Exp Allergy 1996; 26: 335-340
-
(1996)
Clin Exp Allergy
, vol.26
, pp. 335-340
-
-
Blanca, M.1
Garcia, J.2
Vega, J.M.3
-
32
-
-
77950416466
-
Role of minor determinants of amoxicillin in the diagnosis of immediate allergic reactions to amoxicillin
-
Torres MJ, Ariza A, Fernandez J, et al. Role of minor determinants of amoxicillin in the diagnosis of immediate allergic reactions to amoxicillin. Allergy 2010; 65: 590-596
-
(2010)
Allergy
, vol.65
, pp. 590-596
-
-
Torres, M.J.1
Ariza, A.2
Fernandez, J.3
-
33
-
-
84895100034
-
Electrospray ionization collisioninduced dissociation tandem mass spectrometry of amoxicillin and ampicillin and their degradation products
-
Franski R, Czerniel J, Kowalska M, FranskaM. Electrospray ionization collisioninduced dissociation tandem mass spectrometry of amoxicillin and ampicillin and their degradation products. Rapid Commun Mass Spectrom 2014; 28: 713-722
-
(2014)
Rapid Commun Mass Spectrom
, vol.28
, pp. 713-722
-
-
Franski, R.1
Czerniel, J.2
Kowalska, M.3
Franska, M.4
-
35
-
-
0024583919
-
Angioedema and ige antibodies to aspirin: A case report
-
Blanca M, Perez E, Garcia JJ, et al. Angioedema and IgE antibodies to aspirin: a case report. Ann Allergy 1989; 62: 295-298
-
(1989)
Ann Allergy
, vol.62
, pp. 295-298
-
-
Blanca, M.1
Perez, E.2
Garcia, J.J.3
-
37
-
-
83655202895
-
Polymorphisms of aspirin-metabolizing enzymes cyp2c9, nat2 and ugt1a6 in aspirin-intolerant urticaria
-
Palikhe NS, Kim SH, Nam YH, et al. Polymorphisms of aspirin-metabolizing enzymes CYP2C9, NAT2 and UGT1A6 in aspirin-intolerant urticaria. Allergy Asthma Immunol Res 2011; 3: 273-276
-
(2011)
Allergy Asthma Immunol Res
, vol.3
, pp. 273-276
-
-
Palikhe, N.S.1
Kim, S.H.2
Nam, Y.H.3
-
38
-
-
84905024268
-
Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: Multiple albumin adductions in diclofenac patients
-
Hammond TG, Meng X, Jenkins RE, et al. Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients. J Pharmacol Exp Ther 2014; 350: 387-402
-
(2014)
J Pharmacol Exp Ther
, vol.350
, pp. 387-402
-
-
Hammond, T.G.1
Meng, X.2
Jenkins, R.E.3
-
39
-
-
79953661890
-
Chemistry and reactivity of acyl glucuronides
-
Stachulski AV. Chemistry and reactivity of acyl glucuronides. Curr Drug Metab 2011; 12: 215-221
-
(2011)
Curr Drug Metab
, vol.12
, pp. 215-221
-
-
Stachulski, A.V.1
-
40
-
-
33846230114
-
Genetic susceptibility to diclofenacinduced hepatotoxicity: Contribution of ugt2b7, cyp2c8, and abcc2 genotypes
-
Daly AK, Aithal GP, Leathart JB, et al. Genetic susceptibility to diclofenacinduced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology 2007; 132: 272-281
-
(2007)
Gastroenterology
, vol.132
, pp. 272-281
-
-
Daly, A.K.1
Aithal, G.P.2
Leathart, J.B.3
-
41
-
-
10744225344
-
Genetic predisposition to acute gastrointestinal bleeding after nsaids use
-
Martinez C, Blanco G, Ladero JM, et al. Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use. Br J Pharmacol 2004; 141: 205-208
-
(2004)
Br J Pharmacol
, vol.141
, pp. 205-208
-
-
Martinez, C.1
Blanco, G.2
Ladero, J.M.3
-
42
-
-
38949134846
-
Interaction of cyp2c8 and cyp2c9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding
-
Blanco G, Martinez C, Ladero JM, et al. Interaction of CYP2C8 and CYP2C9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding. Pharmacogenet Genomics 2008; 18: 37-43
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 37-43
-
-
Blanco, G.1
Martinez, C.2
Ladero, J.M.3
-
43
-
-
72949108032
-
Genetic polymorphism of the human cytochrome p450 2c9 gene and its clinical significance
-
Wang B, Wang J, Huang SQ, et al. Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance. Curr Drug Metab 2009; 10: 781-834
-
(2009)
Curr Drug Metab
, vol.10
, pp. 781-834
-
-
Wang, B.1
Wang, J.2
Huang, S.Q.3
-
44
-
-
0033816613
-
Relationship of polymorphism in cyp2c9 to genetic susceptibility to diclofenac-induced hepatitis
-
Aithal GP, Day CP, Leathart JB, Daly AK. Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis. Pharmacogenetics 2000; 10: 511-518
-
(2000)
Pharmacogenetics
, vol.10
, pp. 511-518
-
-
Aithal, G.P.1
Day, C.P.2
Leathart, J.B.3
Daly, A.K.4
-
45
-
-
0042591218
-
The metabolism of diclofenac-enzymology and toxicology perspectives
-
Tang W. The metabolism of diclofenac-enzymology and toxicology perspectives. Curr Drug Metab 2003; 4: 319-329
-
(2003)
Curr Drug Metab
, vol.4
, pp. 319-329
-
-
Tang, W.1
-
46
-
-
22344442057
-
Glucuronidation of nonsteroidal antiinflammatory drugs: Identifying the enzymes responsible in human liver microsomes
-
Kuehl GE, Lampe JW, Potter JD, Bigler J. Glucuronidation of nonsteroidal antiinflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug Metab Dispos 2005; 33: 1027-1035
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1027-1035
-
-
Kuehl, G.E.1
Lampe, J.W.2
Potter, J.D.3
Bigler, J.4
-
47
-
-
33646205301
-
Interethnic and intraethnic variability of cyp2c8 and cyp2c9 polymorphisms in healthy individuals
-
Garcia-Martin E, Martinez C, Ladero JM, Agundez JA. Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals. Mol Diagn Ther 2006; 10: 29-40
-
(2006)
Mol Diagn Ther
, vol.10
, pp. 29-40
-
-
Garcia-Martin, E.1
Martinez, C.2
Ladero, J.M.3
Agundez, J.A.4
-
48
-
-
78149443106
-
Diclofenac hypersensitivity: Antibody responses to the parent drug and relevant metabolites
-
Harrer A, Lang R, Grims R, et al. Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites. PloS One 2010; 5: e13707
-
(2010)
PloS One
, vol.5
, pp. e13707
-
-
Harrer, A.1
Lang, R.2
Grims, R.3
-
49
-
-
67650448023
-
Immunoglobulin e-mediated immediate allergic reactions to dipyrone: Value of basophil activation test in the identification of patients
-
Gomez E, Blanca-Lopez N, Torres MJ, et al. Immunoglobulin E-mediated immediate allergic reactions to dipyrone: value of basophil activation test in the identification of patients. Clin Exp Allergy 2009; 39: 1217-1224
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 1217-1224
-
-
Gomez, E.1
Blanca-Lopez, N.2
Torres, M.J.3
-
50
-
-
84910658689
-
Gender and functional cyp2c and nat2 polymorphisms determine the metabolic profile of metamizole
-
Martinez C, Andreu I, Amo G, et al. Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole. Biochem Pharmacol 2014; 92: 457-466
-
(2014)
Biochem Pharmacol
, vol.92
, pp. 457-466
-
-
Martinez, C.1
Andreu, I.2
Amo, G.3
-
51
-
-
0024378440
-
Simultaneous determination of the main metabolites of dipyrone by high-pressure liquid chromatography
-
Damm D. Simultaneous determination of the main metabolites of dipyrone by high-pressure liquid chromatography. Arzneimittelforschung 1989; 39: 1415-1417
-
(1989)
Arzneimittelforschung
, vol.39
, pp. 1415-1417
-
-
Damm, D.1
-
52
-
-
0026544482
-
Formation and excretion of dipyrone metabolites in man
-
Zylber-Katz E, Granit L, Levy M. Formation and excretion of dipyrone metabolites in man. Eur J Clin Pharmacol 1992; 42: 187-191
-
(1992)
Eur J Clin Pharmacol
, vol.42
, pp. 187-191
-
-
Zylber-Katz, E.1
Granit, L.2
Levy, M.3
-
54
-
-
0029013122
-
Metabolism of aminopyrine and derivatives in man: In vivo study of monomorphic and polymorphic metabolic pathways
-
Agundez JA, Martinez C, Benitez J. Metabolism of aminopyrine and derivatives in man: in vivo study of monomorphic and polymorphic metabolic pathways. Xenobiotica 1995; 25: 417-427
-
(1995)
Xenobiotica
, vol.25
, pp. 417-427
-
-
Agundez, J.A.1
Martinez, C.2
Benitez, J.3
-
55
-
-
84937779302
-
Basophil activation test with dipyrone metabolites in the evaluation of immediate allergic reactions to dipyrone
-
Ariza A, Torres MJ, Garcia-Martin E, et al. Basophil activation test with dipyrone metabolites in the evaluation of immediate allergic reactions to dipyrone. Allergy 2014; 69: 133
-
(2014)
Allergy
, vol.69
, pp. 133
-
-
Ariza, A.1
Torres, M.J.2
Garcia-Martin, E.3
-
56
-
-
84876561200
-
Effect of paracetamol use on the modification of the development of asthma by reactive oxygen species genes
-
e1
-
Kang SH, Jung YH, Kim HY, et al. Effect of paracetamol use on the modification of the development of asthma by reactive oxygen species genes. Ann Allergy Asthma Immunol 2013; 110: 364-369; e1
-
(2013)
Ann Allergy Asthma Immunol
, vol.110
, pp. 364-369
-
-
Kang, S.H.1
Jung, Y.H.2
Kim, H.Y.3
-
57
-
-
77954371492
-
Association analysis of n-Acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics
-
Kim JM, Park BL, Park SM, et al. Association analysis of N-Acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics. Pharmacogenomics 2010; 11: 951-958
-
(2010)
Pharmacogenomics
, vol.11
, pp. 951-958
-
-
Kim, J.M.1
Park, B.L.2
Park, S.M.3
-
58
-
-
70449103049
-
Genetic association studies in drug-induced liver injury
-
Daly AK, Day CP. Genetic association studies in drug-induced liver injury. Semin Liver Dis 2009; 29: 400-411
-
(2009)
Semin Liver Dis
, vol.29
, pp. 400-411
-
-
Daly, A.K.1
Day, C.P.2
-
60
-
-
82755165151
-
Pharmacogenetic & pharmacokinetic biomarker for efavirenz based arv and rifampicin based anti-Tb drug induced liver injury in tb-HIV infected patients
-
Yimer G, Ueda N, Habtewold A, et al. Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients. PloS One 2011; 6: e27810
-
(2011)
PloS One
, vol.6
, pp. e27810
-
-
Yimer, G.1
Ueda, N.2
Habtewold, A.3
-
61
-
-
84901768135
-
Genetic basis of drug-induced liver injury: Present and future
-
Urban TJ, Daly AK, Aithal GP. Genetic basis of drug-induced liver injury: present and future. Semin Liver Dis 2014; 34: 123-133
-
(2014)
Semin Liver Dis
, vol.34
, pp. 123-133
-
-
Urban, T.J.1
Daly, A.K.2
Aithal, G.P.3
-
62
-
-
77954660609
-
Genetic and ethnic risk factors associated with drug hypersensitivity
-
Kim SH, Ye YM, Palikhe NS, et al. Genetic and ethnic risk factors associated with drug hypersensitivity. Curr Opin Allergy Clin Immunol 2010; 10: 280-290
-
(2010)
Curr Opin Allergy Clin Immunol
, vol.10
, pp. 280-290
-
-
Kim, S.H.1
Ye, Y.M.2
Palikhe, N.S.3
-
63
-
-
0036000311
-
Acetylator phenotype and genotype in HIV-infected patients with and without sulfonamide hypersensitivity
-
ONeil WM, MacArthur RD, Farrough MJ, et al. Acetylator phenotype and genotype in HIV-infected patients with and without sulfonamide hypersensitivity. J Clin Pharmacol 2002; 42: 613-619
-
(2002)
J Clin Pharmacol
, vol.42
, pp. 613-619
-
-
ONeil, W.M.1
MacArthur, R.D.2
Farrough, M.J.3
-
64
-
-
84879364732
-
Safety evaluation of leflunomide in rheumatoid arthritis
-
Keen HI, Conaghan PG, Tett SE. Safety evaluation of leflunomide in rheumatoid arthritis. Expert Opin Drug Saf 2013; 12: 581-588
-
(2013)
Expert Opin Drug Saf
, vol.12
, pp. 581-588
-
-
Keen, H.I.1
Conaghan, P.G.2
Tett, S.E.3
-
65
-
-
84878682721
-
Leflunomide-induced dress syndrome with renal involvement and vasculitis
-
Pinto B, Dhir V, Krishnan S, Nada R. Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. Clin Rheumatol 2013; 32: 689-693
-
(2013)
Clin Rheumatol
, vol.32
, pp. 689-693
-
-
Pinto, B.1
Dhir, V.2
Krishnan, S.3
Nada, R.4
-
66
-
-
0141569613
-
In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite a771726: Mechanistic similarities with the cytochrome p450-catalyzed dehydration of aldoximes
-
Kalgutkar AS, Nguyen HT, Vaz AD, et al. In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes. Drug Metab Dispos 2003; 31: 1240-1250
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1240-1250
-
-
Kalgutkar, A.S.1
Nguyen, H.T.2
Vaz, A.D.3
-
67
-
-
50849104253
-
Genetic polymorphism of cyp1a2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients
-
Bohanec Grabar P, Rozman B, Tomsic M, et al. Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. Eur J Clin Pharmacol 2008; 64: 871-876
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 871-876
-
-
Bohanec Grabar, P.1
Rozman, B.2
Tomsic, M.3
-
69
-
-
84863662901
-
Polymorphisms in cytochrome p450 2c19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis
-
Wiese MD, Schnabl M, ODoherty C, et al. Polymorphisms in cytochrome P450 2C19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis. Arthritis Res Ther 2012; 14: R163
-
(2012)
Arthritis Res Ther
, vol.14
, pp. R163
-
-
Wiese, M.D.1
Schnabl, M.2
ODoherty, C.3
-
70
-
-
60149111345
-
In vitro metabolism of leflunomide by mouse and human liver microsomes
-
Chan EC, New LS. In vitro metabolism of leflunomide by mouse and human liver microsomes. Drug Metab Lett 2007; 1: 299-305
-
(2007)
Drug Metab Lett
, vol.1
, pp. 299-305
-
-
Chan, E.C.1
New, L.S.2
-
71
-
-
80054752289
-
Inhibiting effects of leflunomide metabolite on overexpression of cd147, mmp-2 and mmp-9 in pma differentiated thp-1 cells
-
Huang JL, Wu SY, Xie XJ, et al. Inhibiting effects of leflunomide metabolite on overexpression of CD147, MMP-2 and MMP-9 in PMA differentiated THP-1 cells. Eur J Pharmacol 2011; 670: 304-310
-
(2011)
Eur J Pharmacol
, vol.670
, pp. 304-310
-
-
Huang, J.L.1
Wu, S.Y.2
Xie, X.J.3
-
72
-
-
84903939581
-
Characterization of a novel cyp2c9 mutation (1009ca) detected in a warfarin-sensitive patient
-
Luo SB, Li CB, Dai DP, et al. Characterization of a novel CYP2C9 mutation (1009CA) detected in a warfarin-sensitive patient. J Pharmacol Sci 2014; 125: 150-156
-
(2014)
J Pharmacol Sci
, vol.125
, pp. 150-156
-
-
Luo, S.B.1
Li, C.B.2
Dai, D.P.3
-
73
-
-
84866098991
-
The differential effect of nat2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype
-
Ruiz JD, Martinez C, Anderson K, et al. The differential effect of NAT2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype. PloS One 2012; 7: e44629
-
(2012)
PloS One
, vol.7
, pp. e44629
-
-
Ruiz, J.D.1
Martinez, C.2
Anderson, K.3
|