Trends in paediatric macrolide use in five European countries - A population-based study

European Journal of Clinical Pharmacology

Volumn 71, Issue 8, 2015, Pages 991-999

  Holstiege, Jakob ^a   Enders, Dirk ^a   Schink, Tania ^a   Innocenti, Francesco ^b,c   Oteri, Alessandro ^d   Bezemer, Irene ^e   Kaguelidou, Florentia ^d,f   Molokhia, Mariam ^g   Poluzzi, Elisabetta ^h   Puccini, Aurora ^h   Ulrichsen, Sinna Pilgaard ⁱ   Sturkenboom, Miriam C ^d   Trifirò, Gianluca ^d,j   Garbe, Edeltraut ^a,k  

^a LEIBNIZ INSTITUTE FOR PREVENTION RESEARCH AND EPIDEMIOLOGY BIPS   (Germany)

^b Health Search   (Italy)

^c Tuscany Regional Health Agency Agenzia Regionale di Sanità della Toscana   (Italy)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e PHARMO INSTITUTE FOR DRUG OUTCOMES RESEARCH   (Netherlands)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^g KING'S COLLEGE LONDON   (United Kingdom)

^h UNIVERSITY OF BOLOGNA   (Italy)

ⁱ AARHUS UNIVERSITY HOSPITAL   (Denmark)

^j UNIVERSITY OF MESSINA   (Italy)

^k UNIVERSITY OF BREMEN   (Germany)

more..

Author keywords

Antibiotic resistance; Electronic healthcare database; Macrolides; Paediatric; Prescription rate; Utilisation

Indexed keywords

AZITHROMYCIN; CLARITHROMYCIN; ERYTHROMYCIN; JOSAMYCIN; MACROLIDE; MIOKAMYCIN; ROKITAMYCIN; ROXITHROMYCIN; SPIRAMYCIN; ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; ARTICLE; AUTUMN; CHILD; DATA BASE; DENMARK; EUROPEAN; GERMANY; GROUPS BY AGE; HUMAN; ITALY; MAJOR CLINICAL STUDY; NETHERLANDS; OUTPATIENT; PEDIATRICS; PLASMA HALF LIFE; PRESCHOOL CHILD; PRESCRIPTION; PRIORITY JOURNAL; SCHOOL CHILD; SEASONAL VARIATION; SPRING; SUMMER; UNITED KINGDOM; WINTER; YOUNG ADULT; DRUG UTILIZATION; EUROPE; INFANT; NEWBORN; RESPIRATORY TRACT INFECTIONS; SEASON; STATISTICS AND NUMERICAL DATA; TRENDS;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG PRESCRIPTIONS; DRUG UTILIZATION; EUROPE; HUMANS; INFANT; INFANT, NEWBORN; MACROLIDES; RESPIRATORY TRACT INFECTIONS; SEASONS;

EID: 84937730287     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-015-1870-7     Document Type: Article

References (25)

1. Holstiege J, Schink T, Molokhia M, Mazzaglia G, Innocenti F, Oteri A, et al. (2014) Systemic antibiotic prescribing to paediatric outpatients in 5 European countries: a population-based cohort study. BMC Pediatr 14:174
2. Granizo JJ, Aguilar L, Casal J, Garcia-Rey C, Dal-Re R, Baquero F (2000) Streptococcus pneumoniae resistance to erythromycin and penicillin in relation to macrolide and beta-lactam consumption in Spain (1979-1997). J Antimicrob Chemother 46:767-773
3. Granizo JJ, Aguilar L, Casal J, Dal-Re R, Baquero F (2000) Streptococcus pyogenes resistance to erythromycin in relation to macrolide consumption in Spain (1986-1997). J Antimicrob Chemother 46:959-964
4. Bergman M, Huikko S, Huovinen P, Paakkari P, Seppälä H (2006) Macrolide and azithromycin use are linked to increased macrolide resistance in Streptococcus pneumonia. Antimicrob Agents Chemother 50:3646-3650
5. García-Rey C, Aguilar L, Baquero F, Casal J, Dal-Ré R (2002) Importance of local variations in antibiotic consumption and geographical differences of erythromycin and penicillin resistance in Streptococcus pneumonia. J Clin Microbiol 40:159-164
6. European Centre for Disease Prevention and Control (2014) Antimicrobial resistance surveillance in Europe 2013. Annual report of the European antimicrobial resistance surveillance network (EARS-Net). Stockholm: ECDC.
7. Adriaenssens N, Coenen S, Versporten A, Muller A, Minalu G, Faes C et al. (2011) European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997-2009). J Antimicrob Chemother 66 Suppl 6:vi37-vi45.
8. Adriaenssens N, Coenen S, Versporten A, Muller A, Minalu G, Faes C, et al. (2011) European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009). J Antimicrob Chemother 66(Suppl 6):vi3-v12
9. Fossum GH, Lindbaek M, Gjelstad S, Dalen I, Kvaerner KJ (2013) Are children carrying the burden of broad-spectrum antibiotics in general practice? Prescription pattern for paediatric outpatients with respiratory tract infections in Norway. BMJ Open 3:1-8
10. Malhotra-Kumar S, Lammens C, Coenen S, Van HK, Goossens H (2007) Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study. Lancet 369:482-490
11. Leclercq R, Courvalin P (2002) Resistance to macrolides and related antibiotics in Streptococcus pneumoniae. Antimicrob Agents Chemother 46:2727-2734
12. Schneider-Lindner V, Quach C, Hanley JA, Suissa S (2011) Secular trends of antibacterial prescribing in UK paediatric primary care. J Antimicrob Chemother 66:424-433
13. Högberg L, Oke T, Geli P, Lundborg CS, Cars O, Ekdahl K. (2005) Reduction in outpatient antibiotic sales for pre-school children: interrupted time series analysis of weekly antibiotic sales data in Sweden 1992-2002. J Antimicrob Chemother 56: 208-215
14. Giannattasio A, Lo Vecchio A, Napolitano C, Di FL, Guarino A (2014) A prospective study on ambulatory care provided by primary care pediatricians during influenza season. Ital J Pediatr 40:38
15. American Academy of Pediatrics Subcommittee on Management of Acute Otitis Media (2004) Diagnosis and management of acute otitis media. Pediatrics 113:1451-1465
16. Chiappini E, Regoli M, Bonsignori F, Sollai S, Parretti A, Galli L, et al. (2011) Analysis of different recommendations from international guidelines for the management of acute pharyngitis in adults and children. Clin Ther 33:48-58
17. NICE Short Clinical Guidelines Technical Team (2008) Respiratory tract infections - antibiotic prescribing. Prescribing of antibiotics for self-limiting respiratory tract infections in adults and children in primary care. London: National Institute for Health and Clinical Excellence
18. Piovani D, Clavenna A, Cartabia M, Bonati M (2012) The regional profile of antibiotic prescriptions in Italian outpatient children. Eur J Clin Pharmacol 68:997-1005
19. Richter SS, Heilmann KP, Dohrn CL, Beekmann SE, Riahi F, Garcia-de-Lomas J, Ferech M, Goossens H, Doern GV (2008) Increasing telithromycin resistance among Streptococcus pyogenes in Europe. J Antimicrob Chemother 61(3):603-611
20. Ranji SR, Steinman MA, Shojania KG, Gonzales R (2008) Interventions to reduce unnecessary antibiotic prescribing: a systematic review and quantitative analysis. Med Care 46:847-862
21. Arnold SR, Straus SE. (2005) Interventions to improve antibiotic prescribing practices in ambulatory care. Cochrane Database Syst Rev 4:CD003539.
22. Fürst J, Cizman M, Mrak J, Kos D, Campbell S, Coenen S, et al. (2014) The influence of a sustained multifaceted approach to improve antibiotic prescribing in Slovenia during the past decade: findings and implications. Expert Rev Anti-Infect Ther 13(2):279-289
23. Huttner B, Goossens H, Verheij T, Harbarth S (2010) Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries. Lancet Infect Dis 10(1):17-31
24. Sabuncu E, David J, Bernède-Bauduin C, Pépin S, Leroy M, Boëlle PY et al. (2009) Significant reduction of antibiotic use in the community after a nationwide campaign in France, 2002-2007. PLoS Med (6):e1000084.
25. Andrews T, Thompson M, Buckley DI, Heneghan C, Deyo R, Redmond N, Lucas PJ, Blair PS, Hay AD. (2012) Interventions to influence consulting and antibiotic use for acute respiratory tract infections in children: a systematic review and meta-analysis. PLoS One 7:e30334