Secular trends of antibacterial prescribing in UK paediatric primary care

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 2, 2011, Pages 424-433

  Schneider Lindner, Verena ^a,b   Quach, Caroline ^a,c   Hanley, James A ^a   Suissa, Samy ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

Antibacterial drug utilization; Children; General Practice Research Database

Indexed keywords

AMINOGLYCOSIDE; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CEPHALOSPORIN DERIVATIVE; CHLORAMPHENICOL; CLINDAMYCIN; FOSFOMYCIN; FUSIDIC ACID; LINEZOLID; MACROLIDE; METHENAMINE HIPPURATE; METRONIDAZOLE; NITROFURANTOIN; PENICILLIN G; PENICILLIN V; POLYMYXIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULFONAMIDE; TEICOPLANIN; TETRACYCLINE DERIVATIVE; TINIDAZOLE; TRIMETHOPRIM; VANCOMYCIN;

ARTICLE; CHILD; CHILD HEALTH CARE; HUMAN; MEDICAL PRACTICE; OUTPATIENT CARE; PRESCRIPTION; PRIMARY MEDICAL CARE; SEX DIFFERENCE; UNITED KINGDOM;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, BACTERIAL; DRUG UTILIZATION; FEMALE; GREAT BRITAIN; HUMANS; INFANT; INFANT, NEWBORN; MALE; PEDIATRICS; PENICILLINS; PHYSICIAN'S PRACTICE PATTERNS; PRIMARY HEALTH CARE;

EID: 78651412572     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq452     Document Type: Article

References (38)

1. WHO. WHO Global Strategy for Containment of Antimicrobial Resistance. Geneva: WHO, 2001. http://www.who.int/entity/csr/resources/publications/drugresist/en/EGlobal_Strat.pdf (18 October 2010, date last accessed).
2. Nyquist AC, Gonzales R, Steiner JF et al. Antibiotic prescribing for children with colds, upper respiratory tract infections, and bronchitis. JAMA 1998; 279: 875-7.
3. Marra F, Patrick DM, Chong M et al. Antibiotic use among children in British Columbia, Canada. J Antimicrob Chemother 2006; 58: 830-9.
4. Finch RG, Metlay JP, Davey PG et al. Educational interventions to improve antibiotic use in the community: report from the International Forum on Antibiotic Resistance (IFAR) colloquium, 2002. Lancet Infect Dis 2004; 4: 44-53.
5. Standing Medical Advisory Committee. The Path of Least Resistance. http://www.advisorybodies.doh.gov.uk/smac1.htm (18 October 2010, date last accessed).
6. Frischer M, Heatlie H, Norwood J et al. Trends in antibiotic prescribing and associated indications in primary care from 1993 to 1997. J Public Health Med 2001; 23: 69-73.
7. Wrigley T, Tinto A, Majeed A. Age- and sex-specific antibiotic prescribing patterns in General Practice in England and Wales, 1994 to 1998. Health Stat Q 2002; 14: 14-20.
8. Sharland M, Kendall H, Yeates D et al. Antibiotic prescribing in general practice and hospital admissions for peritonsillar abscess, mastoiditis, and rheumatic fever in children: time trend analysis. BMJ 2005; 331: 328-9.
9. Ashworth M, Latinovic R, Charlton J et al. Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database. J Public Health (Oxf) 2004; 26: 268-74.
10. Smith GE, Smith S, Heatlie H et al. What has happened to antimicrobial usage in primary care in the United Kingdom since the SMAC report?-description of trends in antimicrobial usage using the General Practice Research Database. J Public Health (Oxf) 2004; 26: 359-64.
11. Sharland M. The use of antibacterials in children: a report of the Specialist Advisory Committee on Antimicrobial Resistance (SACAR) Paediatric Subgroup. J Antimicrob Chemother 2007; 60 Suppl 1: i15-26.
12. Thompson PL, Spyridis N, Sharland M et al. Changes in clinical indications for community antibiotic prescribing for children in the UK from 1996 to 2006: will the new NICE prescribing guidance on upper respiratory tract infections just be ignored? Arch Dis Child 2009; 94: 337-40.
13. The General Practice Research Database. http://www.gprd.com/home/default.asp (18 October 2010, date last accessed).
14. Walley T, Mantgani A. The UK General Practice Research Database. Lancet 1997; 350: 1097-9.
15. Lawrenson R, Williams T, Farmer R. Clinical information for research; the use of general practice databases. J Public Health Med 1999; 21: 299-304.
16. Majeed A, Moser K. Age- and sex-specific antibiotic prescribing patterns in general practice in England and Wales in 1996. Br J Gen Pract 1999; 49: 735-6.
17. Smith S, Smith GE, Heatlie H et al. Reducing variation in antibacterial prescribing rates for 'cough/cold' and sore throat between 1993 and 2001: regional analyses using the general practice research database. Public Health 2006; 120: 752-9.
18. Petersen I, Hayward AC. Antibacterial prescribing in primary care. J Antimicrob Chemother 2007; 60 Suppl 1: i43-7.
19. Joint Formulary Committee. British National Formulary. 60th ed. London: British Medical Association and Royal Pharmaceutical Society of Great Britain, 2010.
20. Otters HB, van der Wouden JC, Schellevis FG et al. Trends in prescribing antibiotics for children in Dutch general practice. J Antimicrob Chemother 2004; 53: 361-6.
21. Patrick DM, Marra F, Hutchinson J et al. Per capita antibiotic consumption: how does a North American jurisdiction compare with Europe? Clin Infect Dis 2004; 39: 11-7.
22. Kozyrskyj AL, Carrie AG, Mazowita GB et al. Decrease in antibiotic use among children in the 1990s: not all antibiotics, not all children. CMAJ 2004; 171: 133-8.
23. Marra F, Monnet DL, Patrick DM et al. A comparison of antibiotic use in children between Canada and Denmark. Ann Pharmacother 2007; 41: 659-66.
24. Cameron AC, Windmeijer FAG. An R-squared measure of goodness of fit for some common nonlinear regression models. J Econometrics 1997; 77: 329-42.
25. Wise R. The relentless rise of resistance? J Antimicrob Chemother 2004; 54: 306-10.
26. Steinman MA, Gonzales R, Linder JA et al. Changing use of antibiotics in community-based outpatient practice, 1991-1999. Ann Intern Med 2003; 138: 525-33.
27. Stille CJ, Andrade SE, Huang SS et al. Increased use of second-generation macrolide antibiotics for children in nine health plans in the United States. Pediatrics 2004; 114: 1206-11.
28. De Jong J, van den Berg PB, de Vries TW et al. Antibiotic drug use of children in the Netherlands from 1999 till 2005. Eur J Clin Pharmacol 2008; 64: 913-9.
29. Goossens H, Ferech M, Vander SR et al. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579-87.
30. Enne VI, Livermore DM, Stephens P et al. Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction. Lancet 2001; 357: 1325-8.
31. Davey P, Ferech M, Ansari F et al. Outpatient antibiotic use in the four administrations of the UK: cross-sectional and longitudinal analysis. J Antimicrob Chemother 2008; 62: 1441-7.
32. National Institute for Health and Clinical Excellence. CG69, Issued July 2008: Respiratory tract infections. Prescribing of Antibiotics for Self-Limiting Respiratory Tract Infections in Adults and Children in Primary Care. http://guidance.nice.org.uk/CG69/Guidance (18 October 2010, date last accessed).
33. Sande-Bruinsma N, Grundmann H, Verloo D et al. Antimicrobial drug use and resistance in Europe. Emerg Infect Dis 2008; 14: 1722-30.
34. Elseviers MM, Ferech M, Vander Stichele RH et al. Antibiotic use in ambulatory care in Europe (ESAC data 1997-2002): trends, regional differences and seasonal fluctuations. Pharmacoepidemiol Drug Saf 2007; 16: 115-23.
35. Deschepper R, Grigoryan L, Lundborg CS et al. Are cultural dimensions relevant for explaining cross-national differences in antibiotic use in Europe? BMC Health Serv Res 2008; 8: 123.
36. Mangione-Smith R, Elliott MN, Stivers T et al. Ruling out the need for antibiotics: are we sending the right message? Arch Pediatr Adolesc Med 2006; 160: 945-52.
37. Francis NA, Butler CC, Hood K et al. Effect of using an interactive booklet about childhood respiratory tract infections in primary care consultations on reconsulting and antibiotic prescribing: a cluster randomised controlled trial. BMJ 2009; 339: b2885.
38. Henderson KL, Müller-Pebody B, Johnson AP et al. First set-up meeting for Antibiotic Resistance and Prescribing in European Children (ARPEC). Euro Surveill 2009; 14: pii=19404.