Macrolide and azithromycin use are linked to increased macrolide resistance in Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 50, Issue 11, 2006, Pages 3646-3650

  Bergman, Miika ^a   Huikko, Solja ^a,b   Huovinen, Pentti ^a   Paakkari, Pirkko ^c   Seppälä, Helena ^a,d   Thompson, Anja Kostiala ^e   Rautio, Merja ^e   Renkonen, Risto ^f   Muotiala, Anna ^f   Vaara, Martti ^g   Carlson, Petteri ^g   Somer, Hannele ^h   Virolainen Julkunen, Anni ⁱ   Korpela, Jukka ^j   Heikkilä, Ritva ^j   Kaukoranta, Suvi Sirkku ^k   Kaukoranta, Heikki ^k   Nissinen, Antti ^l   Ruuska, Pekka ^m   Jägerroos, Henrik ⁿ   Larikka, Martti ^o   Räisänen, Simo ^p   Larinkari, Ulla ^q   Katila, Marja Leena ^r   Kärkkäinen, Ulla ^r   Sarkkinen, Hannu ^s   Kärpänoja, Pauliina ^s   Kauppinen, Maritta ^t   Paltemaa, Seppo ^t   Kärkkäinen, Päivi ^u,v   Pietarinen, Ilmo ^w   Koskela, Markku ^x   Pajarre, Sini ^y   Oinonen, Sinikka ^z   Ratia, Virpi ^z   Grönroos, Paul ^aa   Vuento, Risto ^ab   Liimatainen, Oili ^ab   Siro, Maj Rita ^ac   Eerola, Erkki ^ad   Manninen, Raija ^ad   Meurman, Olli ^ae   Luhtala, Marko ^af   Lager, Katrina ^a   more..

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF TAMPERE   (Finland)

^c National Agency of Medicines   (Finland)

^d TURKU CITY HOSPITAL   (Finland)

^e JORVI HOSPITAL   (Finland)

^f MedixDiacor Laboratory Service   (Finland)

^g HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^h Mehilainen Oy   (Finland)

ⁱ Yhtyneet Laboratoriot Oy   (Finland)

^j KANTA HÄME CENTRAL HOSPITAL   (Finland)

^k NORTH KARELIA CENTRAL HOSPITAL   (Finland)

^l Central Finland Health Care District   (Finland)

^m KAINUU CENTRAL HOSPITAL   (Finland)

ⁿ LAPLAND CENTRAL HOSPITAL   (Finland)

^o Central Hospital of Lansi Pohja   (Finland)

^p Central Ostrobothnian Hospital District   (Finland)

^q KYMENLAAKSO CENTRAL HOSPITAL   (Finland)

^r KUOPIO UNIVERSITY HOSPITAL   (Finland)

^s PÄIJÄT HÄME CENTRAL HOSPITAL   (Finland)

^t SOUTH KARELIA CENTRAL HOSPITAL   (Finland)

^u MIKKELI CENTRAL HOSPITAL   (Finland)

^v Savonlinna Central Hospital   (Finland)

^w OULU DEACONESS INSTITUTE   (Finland)

^x OULU UNIVERSITY HOSPITAL   (Finland)

^y SATAKUNTA CENTRAL HOSPITAL   (Finland)

^z SEINÄJOKI CENTRAL HOSPITAL   (Finland)

^aa Koskiklinikka   (Finland)

^ab TAMPERE UNIVERSITY HOSPITAL   (Finland)

^ac Health Center Pulssi   (Finland)

^ad UNIVERSITY OF TURKU   (Finland)

^ae TURKU UNIVERSITY HOSPITAL   (Finland)

^af VAASA CENTRAL HOSPITAL   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BETA LACTAM ANTIBIOTIC; CEPHALOSPORIN DERIVATIVE; MACROLIDE; PENICILLIN DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; FINLAND; HOSPITAL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PENICILLIN RESISTANCE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STREPTOCOCCUS PNEUMONIAE;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; DRUG UTILIZATION; FINLAND; HOSPITALS; HUMANS; MACROLIDES; PENICILLIN RESISTANCE; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 33750575286     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00234-06     Document Type: Article

References (25)

1. Arason, V. A., A. Gunnlaugsson, J. A. Sigurdsson, H. Erlendsdottir, S. Gudmundsson, and K. G. Kristinsson. 2002. Clonal spread of resistant pneumococci despite diminished antimicrobial use. Microb. Drug Resist. 8:187-192.
2. Austin, D. J., K. G. Kristinsson, and R. M. Andersen. 1999. The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance. Proc. Natl. Acad. Sci. USA 96:1152-1156.
3. Baquero, F. 1999. Evolving resistance patterns of Streptococcus pneumoniae: a link with long-acting macrolide consumption? J. Chemother. 11(Suppl. 1):35-43.
4. Barkai, G., D. Greenberg, N. Givon-Lavi, E. Dreifuss, D. Vardy, and R. Dagan. 2005. Community prescribing and resistant Streptococcus pneumoniae. Emerg. Infect. Dis. 11:829-837.
5. Bergman, M., S. Huikko, M. Pihlajamäki, P. Laippala, E. Palva, P. Huovinen, H. Seppälä, and the Finnish Study Group for Antimicrobial Resistance (FiRe Network). 2004. Effect of macrolide consumption on erythromycin resistance in Streptococcus pyogenes in Finland in 1997-2001. Clin. Infect. Dis. 38:1251-1256.
6. Cizman, M. 2003. The use and resistance to antibiotics in the community. Int. J. Antimicrob. Agents 21:297-307.
7. Donnan, P. T., L. Wei, D. T. Steinke, G. Phillips, R. Clarke, A. Noone, F. M. Sullivan, T. M. MacDonald, and P. G. Davey. 2004. Presence of bacteriuria caused by trimethoprim resistant bacteria in patients prescribed antibiotics: multilevel model with practice and individual patient data. BMJ 328:1297.
8. European Antimicrobial Resistance Surveillance System. 2003. EARSS annual report 2003, European Antimicrobial Resistance Surveillance System, Bilthoven, The Netherlands.
9. Finland, M. 1978. And the walls come tumbling down. More antibiotic resistance, and now the pneumococcus. N. Engl. J. Med. 299:770-771.
10. Finnish Study Group for Antimicrobial Resistance (FiRe Network). 2005, Susceptibility testing methods. [Online.] http;//www.ktl.fi/extras/fire. Accessed 11 January 2006. (In Finnish.)
11. Garcia-Rey, C., L. Aguilar, F. Baquero, J. Casal, and R. Dal-Re. 2002. Importance of local variations in antibiotic consumption and geographical differences of erythromycin and penicillin resistance in Streptococcus pneumoniae. J. Clin. Microbiol. 40:159-164.
12. Goossens, H., M. Ferech, R. Vender Stichele, and M. Elseviers. 2005. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 365:579-587.
13. Huovinen, P. 2005. Mathematical model-tell us the future! J. Antimicrob. Chemother. 56:257-258, 431.
14. Kastner, U., and J. P. Guggenbichler. 2001. Influence of macrolide antibiotics on promotion of resistance in the oral flora of children. Infection 29:251-256.
15. Nasrin, D., P. J. Collignon, L. Roberts, E. J. Wilson, L. S. Pilotto, and R. M. Douglas. 2002. Effect of beta lactam antibiotic use in children on pneumococcal resistance to penicillin; prospective cohort study. BMJ 324:28-30.
16. National Agency for Medicines and the Social Insurance Institution. 2002. Finnish statistics on medicines 2001. National Agency for Medicines and the Social Insurance Institution, Helsinki, Finland.
17. NCCLS. 2003. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 6th ed. Approved standard M7-A6. NCCLS, Wayne, Pa.
18. Nightingale, C. H. 1997. Pharmacokinetics and pharmacodynamics of newer macrolides. Pediatr. Infect. Dis. J. 16:438-443.
19. Pihlajamäki, M., P. Kotilainen, T. Kaurila, T. Klaukka, E. Palva, P. Huovinen, and the Finnish Study Group for Antimicrobial Resistance (FiRe Network). 2001. Macrolide-resistant Streptococcus pneumoniae and use of antimicrobial agents. Clin. Infect. Dis. 33:483-488.
20. Rantala, M., S. Huikko, P. Huovinen, and J. Jalava. 2005. Prevalence and molecular genetics of macrolide resistance among Streptococcus pneumoniae isolates collected in Finland in 2002. Antimicrob. Agents Chemother. 49:4180-4184.
21. Reinert, R. R., A. Al-Lahham, M. Lemperle, C. Tenholte, C. Briefs, S. Haupts, H. H. Gerards, and R. Lutticken. 2002. Emergence of macrolide and penicillin resistance among invasive pneumococcal isolates in Germany. J. Antimicrob. Chemother. 49:61-68.
22. Samore, M. H., M. Lipsitch, S. C. Alder, B. Haddadin, G. Stoddard, J. Williamson, K. Sebastian, K. Carroll, O. Ergonul, Y. Carmeli, and M. A. Sande. 2005. Mechanisms by which antibiotics promote dissemination of resistant pneumococci in human populations. Am. J. Epidemiol. 163:160-170.
23. Schentag, J. J., K. K. Gilliland, and J. A. Paladino. 2001. What have we learned from pharmacokinetic and pharmacodynamic theories? Clin. Infect. Dis. 32(Suppl, 1):S39-S46.
24. Seppälä, H., T. Klaukka, J. Vuopio-Varkila, A. Muotiala, H. Helenius, K. Lager, P. Huovinen, and the Finnish Study Group for Antimicrobial Resistance (FiRe Network). 1997. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. N. Engl. J. Med. 337:441-446.
25. Vanderkooi, O. G., D. E. Low, K. Green, J. E. Powis, and A. McGeer. 2005. Predicting antimicrobial resistance in invasive pneumococcal infections. Clin. Infect. Dis. 40:1288-1297.