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Volumn 22, Issue 7, 2015, Pages 957-964

Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; INITIATION FACTOR 4E; MESSENGER RNA; RECOMBINASE; INTERNAL RIBOSOME ENTRY SITE;

EID: 84937726616     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2015.06.009     Document Type: Article
Times cited : (7)

References (40)
  • 2
    • 77950571108 scopus 로고    scopus 로고
    • New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays
    • J.B. Baell, and G.A. Holloway New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays J. Med. Chem. 53 2010 2719 2740
    • (2010) J. Med. Chem. , vol.53 , pp. 2719-2740
    • Baell, J.B.1    Holloway, G.A.2
  • 3
    • 84908530414 scopus 로고    scopus 로고
    • Chemical con artists foil drug discovery
    • J. Baell, and M.A. Walters Chemical con artists foil drug discovery Nature 513 2014 481 483
    • (2014) Nature , vol.513 , pp. 481-483
    • Baell, J.1    Walters, M.A.2
  • 4
    • 0035476708 scopus 로고    scopus 로고
    • Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes
    • A. Baer, and J. Bode Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes Curr. Opin. Biotech. 12 2001 473 480
    • (2001) Curr. Opin. Biotech. , vol.12 , pp. 473-480
    • Baer, A.1    Bode, J.2
  • 5
    • 84862741954 scopus 로고    scopus 로고
    • Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation
    • P.B. Bitterman, and V.A. Polunovsky Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation Mol. Cancer Ther. 11 2012 1051 1061
    • (2012) Mol. Cancer Ther. , vol.11 , pp. 1051-1061
    • Bitterman, P.B.1    Polunovsky, V.A.2
  • 6
    • 80053343092 scopus 로고    scopus 로고
    • TAL effectors: customizable proteins for DNA targeting
    • A.J. Bogdanove, and D.F. Voytas TAL effectors: customizable proteins for DNA targeting Science 333 2011 1843 1846
    • (2011) Science , vol.333 , pp. 1843-1846
    • Bogdanove, A.J.1    Voytas, D.F.2
  • 8
    • 19644393302 scopus 로고    scopus 로고
    • Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors
    • N.M. Chau, P. Rogers, W. Aherne, V. Carroll, I. Collins, E. McDonald, P. Workman, and M. Ashcroft Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors Cancer Res. 65 2005 4918 4928
    • (2005) Cancer Res. , vol.65 , pp. 4918-4928
    • Chau, N.M.1    Rogers, P.2    Aherne, W.3    Carroll, V.4    Collins, I.5    McDonald, E.6    Workman, P.7    Ashcroft, M.8
  • 9
    • 84866974569 scopus 로고    scopus 로고
    • A coincidence reporter-gene system for high-throughput screening
    • K.C. Cheng, and J. Inglese A coincidence reporter-gene system for high-throughput screening Nat. Methods 9 2012 937
    • (2012) Nat. Methods , vol.9 , pp. 937
    • Cheng, K.C.1    Inglese, J.2
  • 13
    • 38849180436 scopus 로고    scopus 로고
    • Targeting the eukaryotic translation initiation factor 4E for cancer therapy
    • J. Graff, B. Konicek, J. Carter, and E. Marcusson Targeting the eukaryotic translation initiation factor 4E for cancer therapy Cancer Res. 68 2008 631 634
    • (2008) Cancer Res. , vol.68 , pp. 631-634
    • Graff, J.1    Konicek, B.2    Carter, J.3    Marcusson, E.4
  • 15
    • 77958027783 scopus 로고    scopus 로고
    • Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer
    • A.C. Hsieh, and D. Ruggero Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer Clin. Cancer Res. 16 2010 4914 4920
    • (2010) Clin. Cancer Res. , vol.16 , pp. 4914-4920
    • Hsieh, A.C.1    Ruggero, D.2
  • 17
    • 33748558778 scopus 로고    scopus 로고
    • Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44
    • A.W. Kahsai, S. Zhu, D.J. Wardrop, W.S. Lane, and G. Fenteany Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44 Chem. Biol. 13 2006 973 983
    • (2006) Chem. Biol. , vol.13 , pp. 973-983
    • Kahsai, A.W.1    Zhu, S.2    Wardrop, D.J.3    Lane, W.S.4    Fenteany, G.5
  • 18
    • 79960046970 scopus 로고    scopus 로고
    • AAV-mediated gene targeting methods for human cells
    • I.F. Khan, R.K. Hirata, and D.W. Russell AAV-mediated gene targeting methods for human cells Nat. Protoc. 6 2011 482 501
    • (2011) Nat. Protoc. , vol.6 , pp. 482-501
    • Khan, I.F.1    Hirata, R.K.2    Russell, D.W.3
  • 20
    • 84897138228 scopus 로고    scopus 로고
    • Looping back to leap forward: transcription enters a new era
    • M. Levine, C. Cattoglio, and R. Tjian Looping back to leap forward: transcription enters a new era Cell 157 2014 13 25
    • (2014) Cell , vol.157 , pp. 13-25
    • Levine, M.1    Cattoglio, C.2    Tjian, R.3
  • 21
    • 79951840613 scopus 로고    scopus 로고
    • An RNA-zipcode-independent mechanism that localizes Dia1 mRNA to the perinuclear ER through interactions between Dia1 nascent peptide and Rho-GTP
    • G. Liao, X. Ma, and G. Liu An RNA-zipcode-independent mechanism that localizes Dia1 mRNA to the perinuclear ER through interactions between Dia1 nascent peptide and Rho-GTP J. Cell Sci. 124 2011 589 599
    • (2011) J. Cell Sci. , vol.124 , pp. 589-599
    • Liao, G.1    Ma, X.2    Liu, G.3
  • 23
    • 84884856342 scopus 로고    scopus 로고
    • Cas9 as a versatile tool for engineering biology
    • P. Mali, K.M. Esvelt, and G.M. Church Cas9 as a versatile tool for engineering biology Nat. Methods 10 2013 957 963
    • (2013) Nat. Methods , vol.10 , pp. 957-963
    • Mali, P.1    Esvelt, K.M.2    Church, G.M.3
  • 25
    • 40849124249 scopus 로고    scopus 로고
    • A novel high-throughput screening system identifies a small molecule repressive for matrix metalloproteinase-9 expression
    • R. Nair, H. Avila, X. Ma, Z. Wang, M. Lennartz, B.G. Darnay, D.D. Boyd, and C. Yan A novel high-throughput screening system identifies a small molecule repressive for matrix metalloproteinase-9 expression Mol. Pharmacol. 73 2008 919 929
    • (2008) Mol. Pharmacol. , vol.73 , pp. 919-929
    • Nair, R.1    Avila, H.2    Ma, X.3    Wang, Z.4    Lennartz, M.5    Darnay, B.G.6    Boyd, D.D.7    Yan, C.8
  • 30
    • 84879960450 scopus 로고    scopus 로고
    • Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cycline D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors
    • A. Samsonov, N. Zenser, F. Zhang, H. Zhang, J. Fetter, and D. Malkov Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cycline D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors PLoS One 8 2013 e68391
    • (2013) PLoS One , vol.8
    • Samsonov, A.1    Zenser, N.2    Zhang, F.3    Zhang, H.4    Fetter, J.5    Malkov, D.6
  • 31
    • 0028109636 scopus 로고
    • Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci
    • T. Schlake, and J. Bode Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci Biochemistry 33 1994 12746 12751
    • (1994) Biochemistry , vol.33 , pp. 12746-12751
    • Schlake, T.1    Bode, J.2
  • 32
    • 0031875042 scopus 로고    scopus 로고
    • The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binding to HSP90 and shares important biologic activities with geldanamycin
    • T.W. Schulte, and L.M. Neckers The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binding to HSP90 and shares important biologic activities with geldanamycin Cancer Chemother. Pharmacol. 42 1998 273 279
    • (1998) Cancer Chemother. Pharmacol. , vol.42 , pp. 273-279
    • Schulte, T.W.1    Neckers, L.M.2
  • 33
    • 0035894174 scopus 로고    scopus 로고
    • The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts
    • M. Stiborova, C.A. Bieler, M. Wiessler, and E. Frei The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts Biochem. Pharmacol. 62 2001 1675 1684
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 1675-1684
    • Stiborova, M.1    Bieler, C.A.2    Wiessler, M.3    Frei, E.4
  • 34
    • 77953689492 scopus 로고    scopus 로고
    • Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology
    • N. Thorne, J. Inglese, and D.S. Auld Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology Chem. Biol. 17 2010 646 657
    • (2010) Chem. Biol. , vol.17 , pp. 646-657
    • Thorne, N.1    Inglese, J.2    Auld, D.S.3
  • 36
    • 79960062837 scopus 로고    scopus 로고
    • A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells
    • H. Wang, and C. Yan A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells Neoplasia 13 2011 611 619
    • (2011) Neoplasia , vol.13 , pp. 611-619
    • Wang, H.1    Yan, C.2
  • 37
    • 78751533820 scopus 로고    scopus 로고
    • A small-molecule inhibitor of MDMX activates p53 and induces apoptosis
    • H. Wang, X. Ma, S. Ren, J. Buolamwini, and C. Yan A small-molecule inhibitor of MDMX activates p53 and induces apoptosis Mol. Cancer Ther. 10 2011 69 79
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 69-79
    • Wang, H.1    Ma, X.2    Ren, S.3    Buolamwini, J.4    Yan, C.5
  • 38
    • 33747773708 scopus 로고    scopus 로고
    • Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression
    • C. Yan, and D.D. Boyd Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression Mol. Cell. Biol. 26 2006 6357 6371
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 6357-6371
    • Yan, C.1    Boyd, D.D.2
  • 39
    • 84869861385 scopus 로고    scopus 로고
    • Drugging the undruggable: transcription therapy for cancer
    • C. Yan, and H.J. Paul Drugging the undruggable: transcription therapy for cancer Biochim. Biophys. Acta 1835 2013 76 85
    • (2013) Biochim. Biophys. Acta , vol.1835 , pp. 76-85
    • Yan, C.1    Paul, H.J.2
  • 40
    • 2442640603 scopus 로고    scopus 로고
    • A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NF-κB motif drives the transition from a repressed to an activated state of gene expression
    • C. Yan, H. Wang, B. Aggarwal, and D.D. Boyd A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NF-κB motif drives the transition from a repressed to an activated state of gene expression FASEB J. 18 2004 540 541
    • (2004) FASEB J. , vol.18 , pp. 540-541
    • Yan, C.1    Wang, H.2    Aggarwal, B.3    Boyd, D.D.4


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