-
1
-
-
0023805341
-
Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group
-
ISIS-2 (Second International Study of Infarct Survival) Collaborative Group Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group Lancet 2 1988 349 360
-
(1988)
Lancet
, vol.2
, pp. 349-360
-
-
-
2
-
-
0035899289
-
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
-
S Yusuf, F Zhao, SR Mehta, S Chrolavicius, G Tognoni, KK Fox Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation N Engl J Med 345 2001 494 502
-
(2001)
N Engl J Med
, vol.345
, pp. 494-502
-
-
Yusuf, S.1
Zhao, F.2
Mehta, S.R.3
Chrolavicius, S.4
Tognoni, G.5
Fox, K.K.6
-
3
-
-
20144373281
-
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
-
MS Sabatine, CP Cannon, CM Gibson et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation N Engl J Med 352 2005 1179 1189
-
(2005)
N Engl J Med
, vol.352
, pp. 1179-1189
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
-
4
-
-
27644548513
-
Addition of clopidogrel to aspirin in 45 852 patients with acute myocardial infarction: Randomised placebo-controlled trial
-
ZM Chen, LX Jiang, YP Chen Addition of clopidogrel to aspirin in 45 852 patients with acute myocardial infarction: randomised placebo-controlled trial Lancet 366 2005 1607 1621
-
(2005)
Lancet
, vol.366
, pp. 1607-1621
-
-
Chen, Z.M.1
Jiang, L.X.2
Chen, Y.P.3
-
5
-
-
77956290748
-
Dose comparisons of clopidogrel and aspirin in acute coronary syndromes
-
SR Mehta, JP Bassand, S Chrolavicius et al. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes N Engl J Med 363 2010 930 942
-
(2010)
N Engl J Med
, vol.363
, pp. 930-942
-
-
Mehta, S.R.1
Bassand, J.P.2
Chrolavicius, S.3
-
6
-
-
36148983750
-
Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
SD Wiviott, E Braunwald, CH McCabe et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes N Engl J Med 357 2007 2001 2015
-
(2007)
N Engl J Med
, vol.357
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
-
7
-
-
84867177857
-
Prasugrel versus clopidogrel for acute coronary syndromes without revascularization
-
MT Roe, PW Armstrong, KA Fox et al. Prasugrel versus clopidogrel for acute coronary syndromes without revascularization N Engl J Med 367 2012 1297 1309
-
(2012)
N Engl J Med
, vol.367
, pp. 1297-1309
-
-
Roe, M.T.1
Armstrong, P.W.2
Fox, K.A.3
-
8
-
-
84937630802
-
Pharmacology of antithrombotic agents: An exploration of oral antiplatelet and anticoagulant therapies
-
published online March 14.
-
JL Mega, T Simon Pharmacology of antithrombotic agents: an exploration of oral antiplatelet and anticoagulant therapies Lancet 2015 published online March 14. http://dx/doi.org/S0140-6736(15)60243-4
-
(2015)
Lancet
-
-
Mega, J.L.1
Simon, T.2
-
9
-
-
84961289919
-
Extended duration dual antiplatelet therapy and mortality: A systematic review and meta-analysis
-
published online Nov 16.
-
S Elmariah, L Mauri, G Doros et al. Extended duration dual antiplatelet therapy and mortality: a systematic review and meta-analysis Lancet 2014 published online Nov 16. http://dx.doi.org/10.1016/S0140-6736(14)62052-3
-
(2014)
Lancet
-
-
Elmariah, S.1
Mauri, L.2
Doros, G.3
-
10
-
-
84897104036
-
Design and rationale for the Prevention of Cardiovascular Events in Patients with Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial
-
e5
-
MP Bonaca, DL Bhatt, E Braunwald et al. Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial Am Heart J 167 2014 437 444 e5
-
(2014)
Am Heart J
, vol.167
, pp. 437-444
-
-
Bonaca, M.P.1
Bhatt, D.L.2
Braunwald, E.3
-
11
-
-
83655177669
-
Thrombin-receptor antagonist vorapaxar in acute coronary syndromes
-
P Tricoci, Z Huang, C Held et al. Thrombin-receptor antagonist vorapaxar in acute coronary syndromes N Engl J Med 366 2012 20 33
-
(2012)
N Engl J Med
, vol.366
, pp. 20-33
-
-
Tricoci, P.1
Huang, Z.2
Held, C.3
-
12
-
-
84859555815
-
Vorapaxar in the secondary prevention of atherothrombotic events
-
DA Morrow, E Braunwald, MP Bonaca et al. Vorapaxar in the secondary prevention of atherothrombotic events N Engl J Med 366 2012 1404 1413
-
(2012)
N Engl J Med
, vol.366
, pp. 1404-1413
-
-
Morrow, D.A.1
Braunwald, E.2
Bonaca, M.P.3
-
13
-
-
65849268320
-
Aspirin in the primary and secondary prevention of vascular disease: Collaborative meta-analysis of individual participant data from randomised trials
-
C Baigent, L Blackwell, R Collins et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials Lancet 373 2009 1849 1860
-
(2009)
Lancet
, vol.373
, pp. 1849-1860
-
-
Baigent, C.1
Blackwell, L.2
Collins, R.3
-
14
-
-
13844296687
-
Rapid desensitization procedure for patients with aspirin hypersensitivity undergoing coronary stenting
-
S Silberman, C Neukirch-Stoop, PG Steg Rapid desensitization procedure for patients with aspirin hypersensitivity undergoing coronary stenting Am J Cardiol 95 2005 509 510
-
(2005)
Am J Cardiol
, vol.95
, pp. 509-510
-
-
Silberman, S.1
Neukirch-Stoop, C.2
Steg, P.G.3
-
15
-
-
0035908781
-
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study
-
SR Mehta, S Yusuf, RJ Peters et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study Lancet 358 2001 527 533
-
(2001)
Lancet
, vol.358
, pp. 527-533
-
-
Mehta, S.R.1
Yusuf, S.2
Peters, R.J.3
-
16
-
-
33747874088
-
A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
-
G Montalescot, G Sideris, C Meuleman et al. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial J Am Coll Cardiol 48 2006 931 938
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 931-938
-
-
Montalescot, G.1
Sideris, G.2
Meuleman, C.3
-
17
-
-
77958005516
-
Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): A randomised factorial trial
-
SR Mehta, JF Tanguay, JW Eikelboom et al. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial Lancet 376 2010 1233 1243
-
(2010)
Lancet
, vol.376
, pp. 1233-1243
-
-
Mehta, S.R.1
Tanguay, J.F.2
Eikelboom, J.W.3
-
18
-
-
0031035542
-
Coronary stent placement in patients with acute myocardial infarction: Comparison of clinical and angiographic outcome after randomization to antiplatelet or anticoagulant therapy
-
A Schömig, FJ Neumann, H Walter et al. Coronary stent placement in patients with acute myocardial infarction: comparison of clinical and angiographic outcome after randomization to antiplatelet or anticoagulant therapy J Am Coll Cardiol 29 1997 28 34
-
(1997)
J Am Coll Cardiol
, vol.29
, pp. 28-34
-
-
Schömig, A.1
Neumann, F.J.2
Walter, H.3
-
19
-
-
0032481092
-
A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting
-
MB Leon, DS Baim, JJ Popma et al. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting N Engl J Med 339 1998 1665 1671
-
(1998)
N Engl J Med
, vol.339
, pp. 1665-1671
-
-
Leon, M.B.1
Baim, D.S.2
Popma, J.J.3
-
20
-
-
0034622539
-
Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: The clopidogrel aspirin stent international cooperative study (CLASSICS)
-
ME Bertrand, HJ Rupprecht, P Urban, AH Gershlick CLASSICS Investigators Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: the clopidogrel aspirin stent international cooperative study (CLASSICS) Circulation 102 2000 624 629
-
(2000)
Circulation
, vol.102
, pp. 624-629
-
-
Bertrand, M.E.1
Rupprecht, H.J.2
Urban, P.3
Gershlick, A.H.4
-
21
-
-
0037417523
-
Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: A quantitative review of 23 randomised trials
-
EC Keeley, JA Boura, CL Grines Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials Lancet 361 2003 13 20
-
(2003)
Lancet
, vol.361
, pp. 13-20
-
-
Keeley, E.C.1
Boura, J.A.2
Grines, C.L.3
-
22
-
-
0038649988
-
Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
-
PA Gurbel, KP Bliden, BL Hiatt, CM O'Connor Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity Circulation 107 2003 2908 2913
-
(2003)
Circulation
, vol.107
, pp. 2908-2913
-
-
Gurbel, P.A.1
Bliden, K.P.2
Hiatt, B.L.3
O'Connor, C.M.4
-
23
-
-
11844256436
-
Variability in platelet responsiveness to clopidogrel among 544 individuals
-
VL Serebruany, SR Steinhubl, PB Berger, AI Malinin, DL Bhatt, EJ Topol Variability in platelet responsiveness to clopidogrel among 544 individuals J Am Coll Cardiol 45 2005 246 251
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 246-251
-
-
Serebruany, V.L.1
Steinhubl, S.R.2
Berger, P.B.3
Malinin, A.I.4
Bhatt, D.L.5
Topol, E.J.6
-
24
-
-
77958573028
-
Clopidogrel loading dose adjustment according to platelet reactivity monitoring in patients carrying the 2C19∗2 loss of function polymorphism
-
L Bonello, S Armero, O Ait Mokhtar et al. Clopidogrel loading dose adjustment according to platelet reactivity monitoring in patients carrying the 2C19∗2 loss of function polymorphism J Am Coll Cardiol 56 2010 1630 1636
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 1630-1636
-
-
Bonello, L.1
Armero, S.2
Ait Mokhtar, O.3
-
25
-
-
84890025521
-
Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding
-
US Tantry, L Bonello, D Aradi et al. Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding J Am Coll Cardiol 62 2013 2261 2273
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 2261-2273
-
-
Tantry, U.S.1
Bonello, L.2
Aradi, D.3
-
26
-
-
84891060793
-
Expert position paper on the role of platelet function testing in patients undergoing percutaneous coronary intervention
-
D Aradi, RF Storey, A Komócsi et al. Expert position paper on the role of platelet function testing in patients undergoing percutaneous coronary intervention Eur Heart J 35 2014 209 215
-
(2014)
Eur Heart J
, vol.35
, pp. 209-215
-
-
Aradi, D.1
Storey, R.F.2
Komócsi, A.3
-
27
-
-
79952598836
-
Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The GRAVITAS randomized trial
-
MJ Price, PB Berger, PS Teirstein et al. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial JAMA 305 2011 1097 1105
-
(2011)
JAMA
, vol.305
, pp. 1097-1105
-
-
Price, M.J.1
Berger, P.B.2
Teirstein, P.S.3
-
28
-
-
84870032410
-
Bedside monitoring to adjust antiplatelet therapy for coronary stenting
-
JP Collet, T Cuisset, G Rangé et al. Bedside monitoring to adjust antiplatelet therapy for coronary stenting N Engl J Med 367 2012 2100 2109
-
(2012)
N Engl J Med
, vol.367
, pp. 2100-2109
-
-
Collet, J.P.1
Cuisset, T.2
Rangé, G.3
-
29
-
-
84861857758
-
A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: Results of the TRIGGER-PCI (Testing Platelet Reactivity in Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy with Prasugrel) study
-
D Trenk, GW Stone, M Gawaz et al. A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: results of the TRIGGER-PCI (Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel) study J Am Coll Cardiol 59 2012 2159 2164
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 2159-2164
-
-
Trenk, D.1
Stone, G.W.2
Gawaz, M.3
-
30
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
JL Mega, SL Close, SD Wiviott et al. Cytochrome p-450 polymorphisms and response to clopidogrel N Engl J Med 360 2009 354 362
-
(2009)
N Engl J Med
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
-
31
-
-
58749090547
-
Genetic determinants of response to clopidogrel and cardiovascular events
-
T Simon, C Verstuyft, M Mary-Krause et al. Genetic determinants of response to clopidogrel and cardiovascular events N Engl J Med 360 2009 363 375
-
(2009)
N Engl J Med
, vol.360
, pp. 363-375
-
-
Simon, T.1
Verstuyft, C.2
Mary-Krause, M.3
-
32
-
-
58249135635
-
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
-
JP Collet, JS Hulot, A Pena et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study Lancet 373 2009 309 317
-
(2009)
Lancet
, vol.373
, pp. 309-317
-
-
Collet, J.P.1
Hulot, J.S.2
Pena, A.3
-
33
-
-
81855211733
-
Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
-
JL Mega, W Hochholzer, AL Frelinger 3rd et al. Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease JAMA 306 2011 2221 2228
-
(2011)
JAMA
, vol.306
, pp. 2221-2228
-
-
Mega, J.L.1
Hochholzer, W.2
Frelinger, A.L.3
-
34
-
-
80052167250
-
Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention. A collaborative meta-analysis of individual participant data
-
SS Brar, J ten Berg, R Marcucci et al. Impact of platelet reactivity on clinical outcomes after percutaneous coronary intervention. A collaborative meta-analysis of individual participant data J Am Coll Cardiol 58 2011 1945 1954
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 1945-1954
-
-
Brar, S.S.1
Ten Berg, J.2
Marcucci, R.3
-
36
-
-
37349111065
-
Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: The Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial
-
SD Wiviott, D Trenk, AL Frelinger et al. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial Circulation 116 2007 2923 2932
-
(2007)
Circulation
, vol.116
, pp. 2923-2932
-
-
Wiviott, S.D.1
Trenk, D.2
Frelinger, A.L.3
-
37
-
-
42149119040
-
Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: A subanalysis of a randomised trial
-
SD Wiviott, E Braunwald, CH McCabe et al. Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial Lancet 371 2008 1353 1363
-
(2008)
Lancet
, vol.371
, pp. 1353-1363
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
-
38
-
-
67649158245
-
Effect of the novel thienopyridine prasugrel compared with clopidogrel on spontaneous and procedural myocardial infarction in the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial Infarction 38: An application of the classification system from the universal definition of myocardial infarction
-
DA Morrow, SD Wiviott, HD White et al. Effect of the novel thienopyridine prasugrel compared with clopidogrel on spontaneous and procedural myocardial infarction in the Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial Infarction 38: an application of the classification system from the universal definition of myocardial infarction Circulation 119 2009 2758 2764
-
(2009)
Circulation
, vol.119
, pp. 2758-2764
-
-
Morrow, D.A.1
Wiviott, S.D.2
White, H.D.3
-
39
-
-
84920278525
-
2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
-
EA Amsterdam, NK Wenger, RG Brindis et al. 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 130 2014 e344 e426
-
(2014)
J Am Coll Cardiol
, vol.130
, pp. e344-e426
-
-
Amsterdam, E.A.1
Wenger, N.K.2
Brindis, R.G.3
-
40
-
-
84856158305
-
ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)
-
CW Hamm, JP Bassand, S Agewall et al. ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC) Eur Heart J 32 2011 2999 3054
-
(2011)
Eur Heart J
, vol.32
, pp. 2999-3054
-
-
Hamm, C.W.1
Bassand, J.P.2
Agewall, S.3
-
41
-
-
84866732231
-
ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
-
PG Steg, SK James, D Atar et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation Eur Heart J 33 2012 2569 2619
-
(2012)
Eur Heart J
, vol.33
, pp. 2569-2619
-
-
Steg, P.G.1
James, S.K.2
Atar, D.3
-
42
-
-
60649112469
-
Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): Double-blind, randomised controlled trial
-
G Montalescot, SD Wiviott, E Braunwald et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial Lancet 373 2009 723 731
-
(2009)
Lancet
, vol.373
, pp. 723-731
-
-
Montalescot, G.1
Wiviott, S.D.2
Braunwald, E.3
-
43
-
-
55949103494
-
Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38
-
SD Wiviott, E Braunwald, DJ Angiolillo et al. Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38 Circulation 118 2008 1626 1636
-
(2008)
Circulation
, vol.118
, pp. 1626-1636
-
-
Wiviott, S.D.1
Braunwald, E.2
Angiolillo, D.J.3
-
44
-
-
84882265903
-
Prasugrel versus clopidogrel for patients with unstable angina or non-ST-segment elevation myocardial infarction with or without angiography: A secondary, prespecified analysis of the TRILOGY ACS trial
-
SD Wiviott, HD White, EM Ohman et al. Prasugrel versus clopidogrel for patients with unstable angina or non-ST-segment elevation myocardial infarction with or without angiography: a secondary, prespecified analysis of the TRILOGY ACS trial Lancet 382 2013 605 613
-
(2013)
Lancet
, vol.382
, pp. 605-613
-
-
Wiviott, S.D.1
White, H.D.2
Ohman, E.M.3
-
45
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
L Wallentin, RC Becker, A Budaj et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes N Engl J Med 361 2009 1045 1057
-
(2009)
N Engl J Med
, vol.361
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
-
46
-
-
84883624073
-
Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: An analysis from the prospective, randomized PLATO trial
-
PG Steg, RA Harrington, H Emanuelsson et al. Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial Circulation 128 2013 1055 1065
-
(2013)
Circulation
, vol.128
, pp. 1055-1065
-
-
Steg, P.G.1
Harrington, R.A.2
Emanuelsson, H.3
-
47
-
-
82255188048
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: Substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial
-
SK James, MT Roe, CP Cannon et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial BMJ 342 2011 d3527
-
(2011)
BMJ
, vol.342
, pp. d3527
-
-
James, S.K.1
Roe, M.T.2
Cannon, C.P.3
-
48
-
-
74649085430
-
Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): A randomised double-blind study
-
CP Cannon, RA Harrington, S James et al. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study Lancet 375 2010 283 293
-
(2010)
Lancet
, vol.375
, pp. 283-293
-
-
Cannon, C.P.1
Harrington, R.A.2
James, S.3
-
49
-
-
84906656877
-
Ticagrelor vs. Clopidogrel in patients with non-ST-elevation acute coronary syndrome with or without revascularization: Results from the PLATO trial
-
D Lindholm, C Varenhorst, CP Cannon et al. Ticagrelor vs. clopidogrel in patients with non-ST-elevation acute coronary syndrome with or without revascularization: results from the PLATO trial Eur Heart J 35 2014 2083 2093
-
(2014)
Eur Heart J
, vol.35
, pp. 2083-2093
-
-
Lindholm, D.1
Varenhorst, C.2
Cannon, C.P.3
-
50
-
-
84868648318
-
Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: A substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial
-
S Husted, S James, RC Becker et al. Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: a substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial Circ Cardiovasc Qual Outcomes 5 2012 680 688
-
(2012)
Circ Cardiovasc Qual Outcomes
, vol.5
, pp. 680-688
-
-
Husted, S.1
James, S.2
Becker, R.C.3
-
51
-
-
78650174722
-
Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis
-
PG Steg, S James, RA Harrington et al. Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: a Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis Circulation 122 2010 2131 2141
-
(2010)
Circulation
, vol.122
, pp. 2131-2141
-
-
Steg, P.G.1
James, S.2
Harrington, R.A.3
-
52
-
-
77958100874
-
Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
-
L Wallentin, S James, RF Storey et al. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial Lancet 376 2010 1320 1328
-
(2010)
Lancet
, vol.376
, pp. 1320-1328
-
-
Wallentin, L.1
James, S.2
Storey, R.F.3
-
53
-
-
80051550924
-
Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial
-
KW Mahaffey, DM Wojdyla, K Carroll et al. Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial Circulation 124 2011 544 554
-
(2011)
Circulation
, vol.124
, pp. 544-554
-
-
Mahaffey, K.W.1
Wojdyla, D.M.2
Carroll, K.3
-
54
-
-
82955201646
-
Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes
-
RF Storey, RC Becker, RA Harrington et al. Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes Eur Heart J 32 2011 2945 2953
-
(2011)
Eur Heart J
, vol.32
, pp. 2945-2953
-
-
Storey, R.F.1
Becker, R.C.2
Harrington, R.A.3
-
55
-
-
84888002406
-
Cessation of dual antiplatelet treatment and cardiac events after percutaneous coronary intervention (Paris): 2 year results from a prospective observational study
-
R Mehran, U Baber, PG Steg et al. Cessation of dual antiplatelet treatment and cardiac events after percutaneous coronary intervention (Paris): 2 year results from a prospective observational study Lancet 382 2013 1714 1722
-
(2013)
Lancet
, vol.382
, pp. 1714-1722
-
-
Mehran, R.1
Baber, U.2
Steg, P.G.3
-
56
-
-
84895522368
-
Ticagrelor increases adenosine plasma concentration in patients with an acute coronary syndrome
-
L Bonello, M Laine, N Kipson et al. Ticagrelor increases adenosine plasma concentration in patients with an acute coronary syndrome J Am Coll Cardiol 63 2014 872 877
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 872-877
-
-
Bonello, L.1
Laine, M.2
Kipson, N.3
-
57
-
-
84906936926
-
Chronic treatment with ticagrelor limits myocardial infarct size: An adenosine and cyclooxygenase-2-dependent effect
-
MK Nanhwan, S Ling, M Kodakandla, S Nylander, Y Ye, Y Birnbaum Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect Arterioscler Thromb Vasc Biol 34 2014 2078 2085
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 2078-2085
-
-
Nanhwan, M.K.1
Ling, S.2
Kodakandla, M.3
Nylander, S.4
Ye, Y.5
Birnbaum, Y.6
-
58
-
-
84984614477
-
Efficacy of cilostazol on platelet reactivity and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: Insights from a meta-analysis of randomised trials
-
S Bangalore, A Singh, B Toklu et al. Efficacy of cilostazol on platelet reactivity and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: insights from a meta-analysis of randomised trials Open Heart 1 2014 e000068
-
(2014)
Open Heart
, vol.1
, pp. e000068
-
-
Bangalore, S.1
Singh, A.2
Toklu, B.3
-
59
-
-
84873530056
-
Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction
-
D Alexopoulos, I Xanthopoulou, V Gkizas et al. Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction Circ Cardiovasc Interv 5 2012 797 804
-
(2012)
Circ Cardiovasc Interv
, vol.5
, pp. 797-804
-
-
Alexopoulos, D.1
Xanthopoulou, I.2
Gkizas, V.3
-
60
-
-
84858760413
-
Prasugrel versus tirofiban bolus with or without short post-bolus infusion with or without concomitant prasugrel administration in patients with myocardial infarction undergoing coronary stenting
-
The FABOLUS PRO (Facilitation through Aggrastat by drOpping or shortening Infusion Line in patients with ST-segment elevation myocardial infarction compared to or on top of PRasugrel given at loading dOse) trial
-
M Valgimigli, M Tebaldi, G Campo et al. Prasugrel versus tirofiban bolus with or without short post-bolus infusion with or without concomitant prasugrel administration in patients with myocardial infarction undergoing coronary stenting: the FABOLUS PRO (Facilitation through Aggrastat By drOpping or shortening Infusion Line in patients with ST-segment elevation myocardial infarction compared to or on top of PRasugrel given at loading dOse) trial JACC Cardiovasc Interv 5 2012 268 277
-
(2012)
JACC Cardiovasc Interv
, vol.5
, pp. 268-277
-
-
Valgimigli, M.1
Tebaldi, M.2
Campo, G.3
-
61
-
-
84890136652
-
Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: A pooled analysis of patient-level data
-
PG Steg, DL Bhatt, CW Hamm et al. Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data Lancet 382 2013 1981 1992
-
(2013)
Lancet
, vol.382
, pp. 1981-1992
-
-
Steg, P.G.1
Bhatt, D.L.2
Hamm, C.W.3
-
62
-
-
84875779761
-
Effect of platelet inhibition with cangrelor during PCI on ischemic events
-
DL Bhatt, GW Stone, KW Mahaffey et al. Effect of platelet inhibition with cangrelor during PCI on ischemic events N Engl J Med 368 2013 1303 1313
-
(2013)
N Engl J Med
, vol.368
, pp. 1303-1313
-
-
Bhatt, D.L.1
Stone, G.W.2
Mahaffey, K.W.3
-
63
-
-
84883710340
-
Pretreatment with prasugrel in non-ST-segment elevation acute coronary syndromes
-
G Montalescot, L Bolognese, D Dudek et al. Pretreatment with prasugrel in non-ST-segment elevation acute coronary syndromes N Engl J Med 369 2013 999 1010
-
(2013)
N Engl J Med
, vol.369
, pp. 999-1010
-
-
Montalescot, G.1
Bolognese, L.2
Dudek, D.3
-
64
-
-
84871313410
-
Association of clopidogrel pretreatment with mortality, cardiovascular events, and major bleeding among patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis
-
A Bellemain-Appaix, SA O'Connor, J Silvain et al. Association of clopidogrel pretreatment with mortality, cardiovascular events, and major bleeding among patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis JAMA 308 2012 2507 2516
-
(2012)
JAMA
, vol.308
, pp. 2507-2516
-
-
Bellemain-Appaix, A.1
O'Connor, S.A.2
Silvain, J.3
-
65
-
-
84922391666
-
Prehospital ticagrelor in ST-segment elevation myocardial infarction
-
G Montalescot, AW van't Hof, F Lapostolle et al. Prehospital ticagrelor in ST-segment elevation myocardial infarction N Engl J Med 371 2014 1016 1027
-
(2014)
N Engl J Med
, vol.371
, pp. 1016-1027
-
-
Montalescot, G.1
Van'T Hof, A.W.2
Lapostolle, F.3
-
66
-
-
78149451572
-
Underestimated and under-recognized: The late consequences of acute coronary syndrome (GRACE UK-Belgian Study)
-
KA Fox, KF Carruthers, DR Dunbar et al. Underestimated and under-recognized: the late consequences of acute coronary syndrome (GRACE UK-Belgian Study) Eur Heart J 31 2010 2755 2764
-
(2010)
Eur Heart J
, vol.31
, pp. 2755-2764
-
-
Fox, K.A.1
Carruthers, K.F.2
Dunbar, D.R.3
-
67
-
-
33645861080
-
Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events
-
DL Bhatt, KA Fox, W Hacke et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events N Engl J Med 354 2006 1706 1717
-
(2006)
N Engl J Med
, vol.354
, pp. 1706-1717
-
-
Bhatt, D.L.1
Fox, K.A.2
Hacke, W.3
-
68
-
-
34247869852
-
Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial
-
DL Bhatt, MD Flather, W Hacke et al. Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial J Am Coll Cardiol 49 2007 1982 1988
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 1982-1988
-
-
Bhatt, D.L.1
Flather, M.D.2
Hacke, W.3
-
69
-
-
84918772240
-
Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents
-
L Mauri, DJ Kereiakes, RW Yeh et al. Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents N Engl J Med 371 2014 2155 2166
-
(2014)
N Engl J Med
, vol.371
, pp. 2155-2166
-
-
Mauri, L.1
Kereiakes, D.J.2
Yeh, R.W.3
-
71
-
-
84883481368
-
Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention
-
M Lamberts, GH Gislason, JB Olesen et al. Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention J Am Coll Cardiol 62 2013 981 989
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 981-989
-
-
Lamberts, M.1
Gislason, G.H.2
Olesen, J.B.3
-
72
-
-
71749087343
-
Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and Vitamin K antagonists in Denmark: A retrospective analysis of nationwide registry data
-
R Sørensen, ML Hansen, SZ Abildstrom et al. Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data Lancet 374 2009 1967 1974
-
(2009)
Lancet
, vol.374
, pp. 1967-1974
-
-
Sørensen, R.1
Hansen, M.L.2
Abildstrom, S.Z.3
-
75
-
-
84921312430
-
Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions
-
A joint consensus document of the European Society of Cardiology Working Group on Thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS)
-
GY Lip, S Windecker, K Huber et al. Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions: a joint consensus document of the European Society of Cardiology Working Group on Thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS) Eur Heart J 35 2014 3155 3179
-
(2014)
Eur Heart J
, vol.35
, pp. 3155-3179
-
-
Lip, G.Y.1
Windecker, S.2
Huber, K.3
-
76
-
-
84937629900
-
Duration of triple therapy in patients requiring oral anticoagulation after drug-eluting stent implantation: The Intracoronary Stenting and Antithrombotic Regimen - Testing of a six-week versus a six-month clopidogrel treatment Regimen in Patients with concomitant aspirin and oral anticoagulant therapy following drug-eluting stenting (ISAR-TRIPLE) trial
-
in press
-
Fiedler KA, Maeng M, Mehilli J, et al. Duration of triple therapy in patients requiring oral anticoagulation after drug-eluting stent implantation: the Intracoronary Stenting and Antithrombotic Regimen - Testing of a six-week versus a six-month clopidogrel treatment Regimen In Patients with concomitant aspirin and oral anticoagulant therapy following drug-eluting stenting (ISAR-TRIPLE) trial. J Am Coll Cardiol (in press).
-
J Am Coll Cardiol
-
-
Fiedler, K.A.1
Maeng, M.2
Mehilli, J.3
-
77
-
-
84875720372
-
Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: An open-label, randomised, controlled trial
-
WJ Dewilde, T Oirbans, FW Verheugt et al. Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial Lancet 381 2013 1107 1115
-
(2013)
Lancet
, vol.381
, pp. 1107-1115
-
-
Dewilde, W.J.1
Oirbans, T.2
Verheugt, F.W.3
-
78
-
-
79551563636
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: Results from the PLATO (Platelet Inhibition and Patient Outcomes) trial
-
C Held, N Asenblad, JP Bassand et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial J Am Coll Cardiol 57 2011 672 684
-
(2011)
J Am Coll Cardiol
, vol.57
, pp. 672-684
-
-
Held, C.1
Asenblad, N.2
Bassand, J.P.3
-
79
-
-
84864287789
-
Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: Risk-adjusted retrospective data analysis
-
PK Smith, LT Goodnough, JH Levy et al. Mortality benefit with prasugrel in the TRITON-TIMI 38 coronary artery bypass grafting cohort: risk-adjusted retrospective data analysis J Am Coll Cardiol 60 2012 388 396
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 388-396
-
-
Smith, P.K.1
Goodnough, L.T.2
Levy, J.H.3
-
80
-
-
84896532727
-
Vorapaxar in acute coronary syndrome patients undergoing coronary artery bypass graft surgery: Subgroup analysis from the TRACER trial (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome)
-
DJ Whellan, P Tricoci, E Chen et al. Vorapaxar in acute coronary syndrome patients undergoing coronary artery bypass graft surgery: subgroup analysis from the TRACER trial (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome) J Am Coll Cardiol 63 2014 1048 1057
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 1048-1057
-
-
Whellan, D.J.1
Tricoci, P.2
Chen, E.3
|