The effects of high-fat diet exposure in utero on the obesogenic and diabetogenic traits through epigenetic changes in Adiponectin and Leptin gene expression for multiple generations in female mice

Endocrinology (United States)

Volumn 156, Issue 7, 2015, Pages 2482-2491

  Masuyama, Hisashi ^a   Mitsui, Takashi ^a   Nobumoto, Etsuko ^a   Hiramatsu, Yuji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; INSULIN; LEPTIN; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL; MESSENGER RNA;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CALORIC INTAKE; CHROMATIN IMMUNOPRECIPITATION; DIABETOGENIC TRAIT; DNA MODIFICATION; EPIGENETICS; FAT MASS; FEMALE; GENE EXPRESSION; GENETIC TRAIT; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; HIGH THROUGHPUT SCREENING; HOUSEKEEPING GENE; HYPERTENSION; HYPERTRIGLYCERIDEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; INVESTIGATIVE PROCEDURES; LIPID DIET; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; OBESOGENIC TRAIT; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROTEIN DEFICIENCY; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; GENETIC EPIGENESIS; GENETICS; GLUCOSE BLOOD LEVEL; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLIC SYNDROME X; METABOLISM; OBESITY; PREGNANCY; PRENATAL EXPOSURE;

ADIPONECTIN; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIET, HIGH-FAT; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HYPERTRIGLYCERIDEMIA; INSULIN; INSULIN RESISTANCE; LEPTIN; METABOLIC SYNDROME X; MICE; MICE, INBRED ICR; OBESITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIGLYCERIDES;

EID: 84937597130     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-2020     Document Type: Article

References (36)

1. Cnattingius S, Bergström R, Lipworth L, Kramer MS. Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med. 1998;338:147-152.
2. Jansson N, Nilsfelt A, Gellerstedt M, et al. Maternal hormones linking maternal body mass index and dietary intake to birth weight. Am J Clin Nutr. 2008;87:1743-1749.
3. American Diabetes Association. Type 2 diabetes in children and adolescents. Diabetes Care. 2000;23:381-389.
4. Boney CM, Verma A, Tucker R, Vohr BR. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics. 2005;115:e290-e296.
5. Catalano PM, Ehrenberg HM. The short- and long-term implications of maternal obesity on the mother and her offspring. BJOG. 2006;113:1126-1133.
6. Murrin CM, Kelly GE, Tremblay RE, Kelleher CC. Body mass index and h over three generations: evidence from the Lifeways cross-generational cohort study. BMC Public Health. 2012;12:81.
7. Gil-Campos M, Cañete RR, Gil A. Adiponectin, the missing link in insulin resistance and obesity. Clin Nutr. 2004;23:963-974.
8. Fasshauer M, Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia. 2003;46:1594-1603.
9. Stefan N, Stumvoll M. Adiponectin-its role in metabolism and beyond. Horm Metab Res. 2002;34:469-474.
10. Lihn AS, Pedersen SB, Richelsen B. Adiponectin: action, regulation and association to insulin sensitivity. Obes Rev. 2005;6:13-21.
11. Myers MG Jr. Leptin receptor signaling and the regulation of mammalian physiology. Recent Prog Horm Res. 2004;59:287-304.
12. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004;89:2548-2556.
13. Qiu J. Epigenetics: unfinished symphony. Nature. 2006;441:143-145.
14. Choi SW, Friso S. Epigenetics: a new bridge between nutrition and health. Adv Nutr (Bethesda). 2010;1:8-16.
15. Gniuli D, Calcagno A, Caristo ME, et al. Effects of high-fat diet exposure during fetal life on type 2 diabetes development in the progeny. J Lipid Res. 2008;49:1936-1945.
16. Samuelsson AM, Matthews PA, Argenton M, et al. Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programming. Hypertension. 2008;51:383-392.
17. Masuyama H, Hiramatsu Y. Effects of a high fat diet exposure in utero on the metabolic syndrome-like phenomenon in mouse offspring through epigenetic changes in adipocytokine gene expression. Endocrinology. 2012;153(6):2823-2830.
18. Jiménez-Chillarón JC, Díaz R, Martínez D, et al. The role of nutrition on epigenetic modifications and their implications on health. Biochimie. 2012;94:2242-2263.
19. Masuyama H, Hiramatsu Y. Treatment with constitutive androstane receptor ligand during pregnancy prevents insulin resistance in offspring from high-fat diet-induced obese pregnant mice. Am J Physiol Endocrinol Metab. 2012;303(2):E293-E300.
20. Hosker JP, Matthews DR, Rudenski AS, et al. Continuous infusion of glucose with model assessment: measurement of insulin resistance and β-cell function in men. Diabetologia. 1985;28:401-411.
21. Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol Pharmacol. 2002;62:638-646.
22. Gao J, He J, Zhai Y, Wada T, Xie W. The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity. J Biol Chem. 2009;284:25974-25992.
23. van Schothorst EM, Bunschoten A, Schrauwen P, Mensink RP, Keijer J. Effects of a high-fat, low- versus high-glycemic index diet: retardation of insulin resistance involves adipose tissue modulation. FASEB J. 2009;23:1092-1101.
24. Sakurai N, Mochizuki K, Goda T. Modification of histone H3 at lysine 9 on the adiponectin gene in 3T3-L1 adipocytes. J Nutr Sci Vitaminol. 2009;55:131-138.
25. Yokomori N, Tawata M, Onaya T. DNA demethylation modulates mouse leptin promoter activity during the differentiation of 3T3-L1 cells. Diabetologia. 2002;45:140-148.
26. Buckley AJ, Keserü B, Briody J, Thompson M, Ozanne SE, Thompson CH. Altered body composition and metabolism in the male offspring of high fat-fed rats. Metabolism. 2005;54:500-507.
27. Cerf ME, Williams K, Nkomo XI, et al. Islet cell response in the neonatal rat after exposure to a high-fat diet during pregnancy. Am J Physiol Regul Integr Comp Physiol. 2005;288:R1122-R1128.
28. Gregersen S, Dyrskog SE, Storlien LH, Hermansen K. Comparison of a high saturated fat diet with a high carbohydrate diet during pregnancy and lactation: effects on insulin sensitivity in offspring of rats. Metabolism. 2005;54:1316-1322.
29. Cerf ME, Muller CJ, Du Toit DF, Louw J, Wolfe-Coote SA. Hyperglycaemia and reduced glucokinase expression in weanling offspring from dams maintained on a high-fat diet. Br J Nutr. 2006;95:391-396.
30. Srinivasan M, Katewa SD, Palaniyappan A, Pandya JD, Patel MS. Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood. Am J Physiol Endocrinol Metab. 2006;291:E792-E799.
31. Tan KC, Xu A, Chow WS, et al. Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilatation. J Clin Endocrinol Metab. 2004;89:765-769.
32. Ohashi K, Kihara S, Ouchi N, et al. Adiponectin replenishment ameliorates obesity-related hypertension. Hypertension. 2006;47:1108-1116.
33. Carlyle M, Jones OB, Kuo JJ, Hall JE. Chronic cardiovascular and renal actions of leptin: role of adrenergic activity. Hypertension. 2002;39:496-501.
34. Li J, Huang J, Li JS, Chen H, Huang K, Zheng L. Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. J Hepatol. 2012;50:900-907.
35. Drake AJ, Liu L. Intergenerational transmission of programmed effects: public health consequences. Trends Endocrinol Metab. 2010;21:206-213.
36. Daxinger L, Whitelaw E. Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nat Rev Genet. 2012;13:153-162.