Toxicity of colloidal silica nanoparticles administered orally for 90 days in rats

International Journal of Nanomedicine

Volumn 9, Issue , 2014, Pages 67-78

  Kim, Yu Ri ^a   Lee, Seung Young ^c   Lee, Eun Jeong ^a   Park, Sung Ha ^d   Seong, Nak Won ^c   Seo, Heung Sik ^c   Shin, Sung Sup ^c   Kim, Seon Ju ^c   Meang, Eun Ho ^c   Park, Myeong Kyu ^c   Kim, Min Seok ^c   Kim, Cheol Su ^e   Kim, Soo Ki ^e   Son, Sang Wook ^b   Seo, Young Rok ^f   Kang, Boo Hyon ^g   Han, Beom Seok ^h   An, Seong Soo A ⁱ   Lee, Beom Jun ^j   Kim, Meyoung Kon ^a  

^a Department of Biochemistry and Molecular Biology ^*  (South Korea)

^b Korea University   (South Korea)

^c Korea Testing and Research Institute   (South Korea)

^d University of Bath   (United Kingdom)

^e Yonsei University Wonju College of Medicine   (South Korea)

^f Dongguk University   (South Korea)

^g Chemon Inc   (South Korea)

^h Hoseo University   (South Korea)

ⁱ Gachon University   (South Korea)

^j Chungbuk National University   (South Korea)

more..

Author keywords

90 day oral dose toxicity; No observed adverse effect level; Particle size; Silica nanoparticles

Indexed keywords

COLLOIDAL SILICA NANOPARTICLE DERIVATIVE; SILICA NANOPARTICLE; UNCLASSIFIED DRUG; COLLOID; NANOPARTICLE; SILICON DIOXIDE;

ADVERSE DRUG REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEATH; EXPERIMENTAL STUDY; FEMALE; HISTOPATHOLOGY; MALE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRACTICE GUIDELINE; RAT; SPRAGUE DAWLEY RAT; TOXICITY; TOXICITY TESTING; VALIDATION STUDY; ADMINISTRATION AND DOSAGE; ANIMAL; CHEMISTRY; COLLOID; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMALS; COLLOIDS; NANOPARTICLES; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RATS; RATS, SPRAGUE-DAWLEY; SILICON DIOXIDE; TOXICITY TESTS, CHRONIC;

EID: 84937561388     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S57925     Document Type: Article

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