Long-lasting oxidative pulmonary insult in rat after intratracheal instillation of silica nanoparticles doped with cadmium

Toxicology

Volumn 302, Issue 2-3, 2012, Pages 203-211

  Coccini, Teresa ^a   Roda, Elisa ^a   Barni, Sergio ^a   Signorini, Cinzia ^b   Manzo, Luigi ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

COX; In vivo; iNOS; Isoprostanes; Nanotoxicology; Superoxide dismutase

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPROSTANE DERIVATIVE; NANOPARTICLE; SILICON DIOXIDE; SUPEROXIDE DISMUTASE; NOS2 PROTEIN, RAT; PTGS2 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DESQUAMATION; GAS CHROMATOGRAPHY; GRANULOMATOSIS; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATORY CELL; INSTILLATION SITE IRRITATION; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; LUNG PARENCHYMA; MALE; MEDICAL DEVICE COMPLICATION; NANOTOXICOLOGY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TANDEM MASS SPECTROMETRY; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; LUNG; LUNG LAVAGE; METABOLISM; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SPRAGUE DAWLEY RAT; X RAY DIFFRACTION;

RATTUS;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CADMIUM; CYCLOOXYGENASE 2; F2-ISOPROSTANES; IMMUNOHISTOCHEMISTRY; LUNG; MALE; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; NANOPARTICLES; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SILICON DIOXIDE; SUPEROXIDE DISMUTASE; X-RAY DIFFRACTION;

EID: 84897119347     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.07.019     Document Type: Article

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