Type 2 diabetes alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and recovery

Diabetologia

Volumn 58, Issue 8, 2015, Pages 1845-1854

  Hansen, Jakob S ^a   Zhao, Xinjie ^b   Irmler, Martin ^c   Liu, Xinyu ^b   Hoene, Miriam ^d   Scheler, Mika ^c,e   Li, Yanjie ^b   Beckers, Johannes ^c,e,f   Hrabĕ de Angelis, Martin ^c,e,f   Häring, Hans Ulrich ^d,e   Pedersen, Bente K ^a   Lehmann, Rainer ^d,e   Xu, Guowang ^b   Plomgaard, Peter ^a   Weigert, Cora ^d,e  

^a Rigshospitalet   (Denmark)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Basic science; Exercise; Human; Metabolomics; Microarray; Pathophysiology metabolism

Indexed keywords

ARGININE; CYSTEINE; FLOTILLIN 1; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCINE; INSULIN; LACTIC ACID; THREONINE; AMINO ACID; ANTIDIABETIC AGENT; GLIMEPIRIDE; GLUCOSE BLOOD LEVEL; METFORMIN; SULFONYLUREA DERIVATIVE;

ADULT; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ARTICLE; BICYCLE ERGOMETER; BODY FAT; CBLB GENE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC PATIENT; EXERCISE; EXOC7 GENE; FBP2 GENE; GENE; GENE CONTROL; GENE EXPRESSION; GLUCOSE METABOLISM; GLYCOLYSIS; HK2 GENE; HUMAN; INSULIN BLOOD LEVEL; LACTATE BLOOD LEVEL; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLOMICS; NON INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN CONSUMPTION; PFKFB1 GENE; PFKFB3 GENE; PFKM GENE; PRIORITY JOURNAL; RAB13 GENE; RABGAP1 GENE; SKELETAL MUSCLE; SLC2A4RG GENE; TRANSCRIPTOMICS; UPREGULATION; CALORIMETRY; CARBOHYDRATE METABOLISM; DIABETES MELLITUS, TYPE 2; GENETICS; GLUCOSE BLOOD LEVEL; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

AMINO ACIDS; BLOOD GLUCOSE; CALORIMETRY, INDIRECT; CARBOHYDRATE METABOLISM; DIABETES MELLITUS, TYPE 2; EXERCISE; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; MALE; METFORMIN; MIDDLE AGED; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; SULFONYLUREA COMPOUNDS;

EID: 84937525633     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3584-x     Document Type: Article

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