The regeneration and augmentation of bone with injectable osteogenic cell sheet in a rat critical fracture healing model

Injury

Volumn 46, Issue 8, 2015, Pages 1457-1464

  Shimizu, Takamasa ^a   Akahane, Manabu ^b   Morita, Yusuke ^c   Omokawa, Shohei ^a   Nakano, Kenichi ^a   Kira, Tsutomu ^a   Onishi, Tadanobu ^a   Inagaki, Yusuke ^a   Okuda, Akinori ^a   Kawate, Kenji ^a   Tanaka, Yasuhito ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c DOSHISHA UNIVERSITY   (Japan)

Author keywords

Bone marrow stromal cell; Bone regeneration; Bone tissue engineering; Extracellular matrix; Fracture healing; Injectable bone; Nonunion; Osteogenic cell sheet

Indexed keywords

PHOSPHATE BUFFERED SALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DEVELOPMENT; BONE MARROW STROMA CELL; BONE RADIOGRAPHY; BONE REGENERATION; BONE REMODELING; CALLUS; CONTROLLED STUDY; FRACTURE HEALING; HISTOPATHOLOGY; MALE; MICRO-COMPUTED TOMOGRAPHY; MINIMALLY INVASIVE PROCEDURE; NONHUMAN; OSTEOBLAST; OSTEOGENIC CELL SHEET; PERIOSTEUM; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; FEMUR; FEMUR FRACTURE; FISCHER 344 RAT; FRACTURE NONUNION; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; RADIOGRAPHY; REPRODUCIBILITY;

ANIMALS; BIOMECHANICAL PHENOMENA; BONE REGENERATION; DISEASE MODELS, ANIMAL; FEMORAL FRACTURES; FEMUR; FRACTURE HEALING; FRACTURES, UNUNITED; MALE; MESENCHYMAL STROMAL CELLS; OSTEOBLASTS; RATS; RATS, INBRED F344; REPRODUCIBILITY OF RESULTS;

EID: 84937524761     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2015.04.031     Document Type: Article

References (35)

1. I. Pountos, T. Georgouli, K. George, and P.V. Giannoudis Efficacy of minimally invasive techniques for enhancement of fracture healing: evidence today Int Orthop 34 1 2010 3 12
2. A. Schindeler, M.M. McDonald, P. Bokko, and D.G. Little Bone remodeling during fracture repair: the cellular picture Semin Cell Dev Biol 19 5 2008 459 466
3. C. Myeroff, and M. Archdeacon Autologous bone graft: donor sites and techniques J Bone Joint Surg Am 93 23 2011 2227 2236
4. P. Hernigou, A. Poignard, F. Beaujean, and H. Rouard Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells J Bone Joint Surg Am 87 7 2005 1430 1437
5. G.F. Muschler, C. Boehm, and K. Easley Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume J Bone Joint Surg Am 79 11 1997 1699 1709
6. G.F. Muschler, H. Nitto, C.A. Boehm, and K.A. Easley Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors J Orthop Res 19 1 2001 117 125
7. Y. Xia, F. Mei, Y. Duan, Y. Gao, Z. Xiong, T. Zhang, and et al. Bone tissue engineering using bone marrow stromal cells and an injectable sodium alginate/gelatin scaffold J Biomed Mater Res A 100 4 2012 1044 1050
8. Y. Yamada, S. Nakamura, K. Ito, T. Kohgo, H. Hibi, T. Nagasaka, and et al. Injectable tissue-engineered bone using autogenous bone marrow-derived stromal cells for maxillary sinus augmentation: clinical application report from a 2-6-year follow-up Tissue Eng Part A 14 10 2008 1699 1707
9. L. Zhao, M. Tang, M.D. Weir, M.S. Detamore, and H.H. Xu Osteogenic media and rhBMP-2-induced differentiation of umbilical cord mesenchymal stem cells encapsulated in alginate microbeads and integrated in an injectable calcium phosphate-chitosan fibrous scaffold Tissue Eng Part A 17 7-8 2011 969 979
10. J.M. Anderson, A. Rodriguez, and D.T. Chang Foreign body reaction to biomaterials Semin Immunol 20 2 2008 86 100
11. J. Yang, M. Yamato, C. Kohno, A. Nishimoto, H. Sekine, F. Fukai, and et al. Cell sheet engineering: recreating tissues without biodegradable scaffolds Biomaterials 26 33 2005 6415 6422
12. T. Okano, N. Yamada, H. Sakai, and Y. Sakurai A novel recovery system for cultured cells using plasma-treated polystyrene dishes grafted with poly (N-isopropylacrylamide) J Biomed Mater Res 27 10 1993 1243 1251
13. K. Nishida, M. Yamato, Y. Hayashida, K. Watanabe, N. Maeda, H. Watanabe, and et al. Functional bioengineered corneal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface Transplantation 77 3 2004 379 385
14. T. Shimizu, M. Yamato, Y. Isoi, T. Akutsu, T. Setomaru, K. Abe, and et al. Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces Circ Res 90 3 2002 e40
15. K. Kano, M. Yamato, and T. Okano Ectopic transplantation of hepatocyte sheets fabricated with temperature-responsive culture dishes Hepatol Res 38 11 2008 1140 1147
16. A. Kushida, M. Yamato, Y. Isoi, A. Kikuchi, and T. Okano A noninvasive transfer system for polarized renal tubule epithelial cell sheets using temperature-responsive culture dishes Eur Cell Mater 10 2005 23 30
17. Y. Zhou, F. Chen, S.T. Ho, M.A. Woodruff, T.M. Lim, and D.W. Hutmacher Combined marrow stromal cell-sheet techniques and high-strength biodegradable composite scaffolds for engineered functional bone grafts Biomaterials 28 5 2007 814 824
18. M. Akahane, A. Nakamura, H. Ohgushi, H. Shigematsu, Y. Dohi, and Y. Takakura Osteogenic matrix sheet-cell transplantation using osteoblastic cell sheet resulted in bone formation without scaffold at an ectopic site J Tissue Eng Regen Med 2 4 2008 196 201
19. L.F. Mendes, R.P. Pirraco, W. Szymczyk, A.M. Frias, T.C. Santos, R.L. Reis, and et al. Perivascular-like cells contribute to the stability of the vascular network of osteogenic tissue formed from cell sheet-based constructs PLoS One 7 7 2012 e41051
20. K. Uematsu, T. Kawase, M. Nagata, K. Suzuki, K. Okuda, H. Yoshie, and et al. Tissue culture of human alveolar periosteal sheets using a stem-cell culture medium (MesenPRO-RS™): in vitro expansion of CD146-positive cells and concomitant upregulation of osteogenic potential in vivo Stem Cell Res 10 1 2013 1 19
21. C.H. Chang, C.H. Chen, H.W. Liu, S.W. Whu, S.H. Chen, C.L. Tsai, and et al. Bioengineered periosteal progenitor cell sheets to enhance tendon-bone healing in a bone tunnel Biomed J 35 6 2012 473 480
22. A. Nakamura, M. Akahane, H. Shigematsu, M. Tadokoro, Y. Morita, H. Ohgushi, and et al. Cell sheet transplantation of cultured mesenchymal stem cells enhances bone formation in a rat nonunion model Bone 46 2 2010 418 424
23. M. Akahane, H. Shigematsu, M. Tadokoro, T. Ueha, T. Matsumoto, Y. Tohma, and et al. Scaffold-free cell sheet injection results in bone formation J Tissue Eng Regen Med 4 5 2010 404 411
24. D.W. Hutmacher, and M. Sittinger Periosteal cells in bone tissue engineering Tissue Eng 9 Suppl 1 2003 S45 S64
25. C. Colnot, S. Huang, and J. Helms Analyzing the cellular contribution of bone marrow to fracture healing using bone marrow transplantation in mice Biochem Biophys Res Commun 350 3 2006 557 561
26. G.D. Collett, and A.E. Canfield Angiogenesis and pericytes in the initiation of ectopic calcification Circ Res 96 9 2005 930 938
27. G.Z. Eghbali-Fatourechi, J. Lamsam, D. Fraser, D. Nagel, B.L. Riggs, and S. Khosla Circulating osteoblast-lineage cells in humans N Engl J Med 352 19 2005 1959 1966
28. M.N. Rumi, G.S. Deol, K.P. Singapuri, and V.D. Pellegrini Jr. The origin of osteoprogenitor cells responsible for heterotopic ossification following hip surgery: an animal model in the rabbit J Orthop Res 23 1 2005 34 40
29. S. Sethe, A. Scutt, and A. Stolzing Aging of mesenchymal stem cells Ageing Res Rev 5 1 2008 91 116
30. K. Kaspar, G. Matziolis, P. Strube, U. Senturk, S. Dormann, H.J. Bail, and et al. A new animal model for boneatrophic nonunion: fixation by external fixator J Orthop Res 26 12 2008 1649 1655
31. A. Peters, D. Toben, J. Lienau, H. Schell, H.J. Bail, G. Matziolis, and et al. Locally applied osteogenic predifferentiated progenitor cells are more effective than undifferentiated mesenchymal stem cells in the treatment of delayed bone healing Tissue Eng Part A 15 10 2009 2947 2954
32. D. Ma, C. Zhong, H. Yao, Y. Liu, F. Chen, J. Li, and et al. Engineering injectable bone using bone marrow stromal cell aggregates Stem Cells Dev 20 6 2011 989 999
33. C.M. Nelson, and M.J. Bissell Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer Annu Rev Cell Dev Biol 22 2006 287 309
34. S.L. Dallas, J.L. Rosser, G.R. Mundy, and L.F. Bonewald Proteolysis of latent transforming growth factor-beta (TGF-beta)-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix J Biol Chem 277 24 2002 21352 21360
35. M. Maeda, M. Yamato, M. Kanzaki, H. Iseki, and T. Okano Thoracoscopic cell sheet transplantation with a novel device J Tissue Eng Regen Med 3 4 2009 255 259