Autogenous bone graft: Donor sites and techniques

Journal of Bone and Joint Surgery

Volumn 93, Issue 23, 2011, Pages 2227-2236

  Myeroff, Chad ^a   Archdeacon, Michael ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTHRODESIS; BLOOD VESSEL INJURY; BONE CONDUCTION; BONE GRAFT; BONE REMODELING; BRAIN INJURY; CANCELLOUS BONE GRAFT; CORTICAL BONE GRAFT; CORTICOCANCELLOUS BONE GRAFT; DONOR; FRACTURE; FRACTURE NONUNION; HEMATOMA; HUMAN; INCISIONAL HERNIA; LIMB SALVAGE; NERVE INJURY; OUTCOME ASSESSMENT; PAIN; POSTOPERATIVE COMPLICATION; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; REVIEW; SEROMA; SURGICAL TECHNIQUE; TREATMENT INDICATION; VASCULAR BONE GRAFT;

EID: 83455206893     PISSN: 00219355     EISSN: 15351386     Source Type: Journal    
DOI: 10.2106/JBJS.J.01513     Document Type: Review

References (95)

1. Wright JG, Swiontkowski MF, Heckman JD. Introducing levels of evidence to the journal. J Bone Joint Surg Am. 2003;85:1-3. (Pubitemid 36537965)
2. Wright JG, Einhorn TA, Heckman JD. Grades of recommendation. J Bone Joint Surg Am. 2005;87:1909-10. (Pubitemid 41279119)
3. Westrich GH, Geller DS, O'Malley MJ, Deland JT, Helfet DL. Anterior iliac crest bone graft harvesting using the corticocancellous reamer system. J Orthop Trauma. 2001;15:500-6. (Pubitemid 32998515)
4. Kakar S, Tsiridis E, Einhorn T. Bone grafting and enhancement of fracture repair. In: Bucholz RW, Heckman JD, Court-Brown C, Tornetta P, Koval KJ, Wirth MA, editors. Rockwood and Green's fractures in adults. 6th ed. Vol 1. Philadelphia: Lippincott Williams and Wilkins; 2006. p 313-31.
5. Finkemeier CG. Bone-grafting and bone-graft substitutes. J Bone Joint Surg Am. 2002;84:454-64. (Pubitemid 37107720)
6. Khan SN, Cammisa FP Jr, Sandhu HS, Diwan AD, Girardi FP, Lane JM. The biology of bone grafting. J Am Acad Orthop Surg. 2005;13:77-86.
7. Ebraheim NA, Elgafy H, Xu R. Bone-graft harvesting from iliac and fibular donor sites: techniques and complications. J Am Acad Orthop Surg. 2001;9:210-8.
8. Brawley SC, Simpson RB. Results of an alternative autogenous iliac crest bone graft harvest method. Orthopedics. 2006;29:342-6.
9. Gazdag AR, Lane JM, Glaser D, Forster RA. Alternatives to autogenous bone graft: efficacy and indications. J Am Acad Orthop Surg. 1995;3:1-8.
10. Sen MK, Miclau T. Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? Injury. 2007;38:S75-80. (Pubitemid 46440932)
11. Bauer TW, Muschler GF. Bone graft materials. An overview of the basic science. Clin Orthop Relat Res. 2000;371:10-27. (Pubitemid 30090817)
12. Dell PC, Burchardt H, Glowczewskie FP Jr. A roentgenographic, biomechanical, and histological evaluation of vascularized and non-vascularized segmental fibular canine autografts. J Bone Joint Surg Am. 1985;67:105-12. (Pubitemid 15193004)
13. Olsen BS, Vaesel MT, Søjbjerg JO. Treatment of midshaft clavicular nonunion with plate fixation and autologous bone grafting. J Shoulder Elbow Surg. 1995;4:337-44.
14. Bradbury N, Hutchinson J, Hahn D, Colton CL. Clavicular nonunion. 31/32 healed after plate fixation and bone grafting. Acta Orthop Scand. 1996;67:367-70. (Pubitemid 26288318)
15. Sanders R. Displaced intra-articular fractures of the calcaneus. J Bone Joint Surg Am. 2000;82:225-50. (Pubitemid 30097023)
16. Easley ME, Trnka HJ, Schon LC, Myerson MS. Isolated subtalar arthrodesis. J Bone Joint Surg Am. 2000;82:613-24. (Pubitemid 30307863)
17. Cypher TJ, Grossman JP. Biological principles of bone graft healing. J Foot Ankle Surg. 1996;35:413-7. (Pubitemid 26378157)
18. Mendicino RW, Leonheart E, Shromoff P. Techniques for harvesting autogenous bone graft of the lower extremity. J Foot Ankle Surg. 1996;35:428-35. (Pubitemid 26378159)
19. Nusbickel FR, Dell PC, McAndrew MP, Moore MM. Vascularized autografts for reconstruction of skeletal defects following lower extremity trauma. A review. Clin Orthop Relat Res. 1989;243:65-70. (Pubitemid 19165365)
20. Patel JC, Watson K, Joseph E, Garcia J, Wollstein R. Long-term complications of distal radius bone grafts. J Hand Surg Am. 2003;28:784-8. (Pubitemid 37175360)
21. Bruno RJ, Cohen MS, Berzins A, Sumner DR. Bone graft harvesting from the distal radius, olecranon, and iliac crest: a quantitative analysis. J Hand Surg Am. 2001;26:135-41. (Pubitemid 32126039)
22. Laursen M, Christensen FB, Bünger C, Lind M. Optimal handling of fresh cancellous bone graft: different peroperative storing techniques evaluated by in vitro osteoblast-like cell metabolism. Acta Orthop Scand. 2003;74:490-6. (Pubitemid 37108472)
23. Maus U, Andereya S, Gravius S, Siebert CH, Schippmann T, Ohnsorge JA, Niedhart C. How to store autologous bone graft perioperatively: an in vitro study. Arch Orthop Trauma Surg. 2008;128:1007-11.
24. Lindsey RW, Probe R, Miclau T, Alexander JW, Perren SM. The effects of antibiotic-impregnated autogeneic cancellous bone graft on bone healing. Clin Orthop Relat Res. 1993;291:303-12. (Pubitemid 23164275)
25. Alt V, Nawab A, Seligson D. Bone grafting from the proximal tibia. J Trauma. 1999;47:555-7. (Pubitemid 29444397)
26. Chan YS, Ueng SW, Wang CJ, Lee SS, Chen CY, Shin CH. Antibiotic- impregnated autogenic cancellous bone grafting is an effective and safe method for the management of small infected tibial defects: a comparison study. J Trauma. 2000;48:246-55. (Pubitemid 30112074)
27. Chen CE, Ko JY, Pan CC. Results of vancomycin-impregnated cancellous bone grafting for infected tibial nonunion. Arch Orthop Trauma Surg. 2005;25:369-75.
28. Naal FD, Salzmann GM, von Knoch F, Tuebel J, Diehl P, Gradinger R, Schauwecker J. The effects of clindamycin on human osteoblasts in vitro. Arch Orthop Trauma Surg. 2008;128:317-23.
29. Salzmann GM, Naal FD, von Knoch F, Tuebel J, Gradinger R, Imhoff AB, Schauwecker J. Effects of cefuroxime on human osteoblasts in vitro. J Biomed Mater Res A. 2007;82:462-8. (Pubitemid 47051678)
30. Belthur MV, Conway JD, Jindal G, Ranade A, Herzenberg JE. Bone graft harvest using a new intramedullary system. Clin Orthop Relat Res. 2008;466:2973-80.
31. Singh JR, Nwosu U, Egol KA. Long-term functional outcome and donor-site morbidity associated with autogenous iliac crest bone grafts utilizing a modified anterior approach. Bull NYU Hosp Jt Dis. 2009;67:347-51.
32. Meeder PJ, Eggers C. Techniques for obtaining autogenous bone graft. Injury. 1994;25:A5-16.
33. Arrington ED, Smith WJ, Chambers HG, Bucknell AL, Davino NA. Complications of iliac crest bone graft harvesting. Clin Orthop Relat Res. 1996;329:300-9. (Pubitemid 26274684)
34. Smith SE, DeLee JC, Ramamurthy S. Ilioinguinal neuralgia following iliac bone-grafting. Report of two cases and review of the literature. J Bone Joint Surg Am. 1984;66:1306-8. (Pubitemid 15206115)
35. Bimmel R, Govaers K. Does harvesting of iliac bone grafts with an acetabular reamer reduce complication rate? Acta Orthop Belg. 2006;72:598-602. (Pubitemid 44845249)
36. Ilankovan V, Stronczek M, Telfer M, Peterson LJ, Stassen LF, Ward-Booth P. A prospective study of trephined bone grafts of the tibial shaft and iliac crest. Br J Oral Maxillofac Surg. 1998;36:434-9. (Pubitemid 28564308)
37. Behairy YM, Al-Sebai W. A modified technique for harvesting full-thickness iliac crest bone graft. Spine (Phila Pa 1976). 2001;26:695-7.
38. Gossman DG, Rosenblum W, Arosarena O, Valentino J. The acetabular reamer: a unique tool for anterior iliac crest bone graft harvesting. Laryngoscope. 2005;115:557-9. (Pubitemid 40328013)
39. Dick W. Use of the acetabular reamer to harvest autogeneic bone graft material: a simple method for producing bone paste. Arch Orthop Trauma Surg. 1986;105:235-8. (Pubitemid 17055586)
40. Sandhu HS, Grewal HS, Parvataneni H. Bone grafting for spinal fusion. Orthop Clin North Am. 1999;30:685-98. (Pubitemid 29471309)
41. Ahlmann E, Patzakis M, Roidis N, Shepherd L, Holtom P. Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am. 2002;84:716-20.
42. Younger EM, Chapman MW. Morbidity at bone graft donor sites. J Orthop Trauma. 1989;3:192-5.
43. Goulet JA, Senunas LE, DeSilva GL, Greenfield ML. Autogenous iliac crest bone graft. Complications and functional assessment. Clin Orthop Relat Res. 1997;339:76-81. (Pubitemid 27250717)
44. Banwart JC, Asher MA, Hassanein RS. Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine (Phila Pa 1976). 1995;20:1055-60.
45. Schnee CL, Freese A, Weil RJ, Marcotte PJ. Analysis of harvest morbidity and radiographic outcome using autograft for anterior cervical fusion. Spine (Phila Pa 1976). 1997;22:2222-7.
46. Sawin PD, Traynelis VC, Menezes AH. A comparative analysis of fusion rates and donor-site morbidity for autogeneic rib and iliac crest bone grafts in posterior cervical fusions. J Neurosurg. 1998;88:255-65. (Pubitemid 28063598)
47. Summers BN, Eisenstein SM. Donor site pain from the ilium. A complication of lumbar spine fusion. J Bone Joint Surg Br. 1989;71:677-80. (Pubitemid 19211233)
48. Dusseldorp JR, Mobbs RJ. Iliac crest reconstruction to reduce donor-site morbidity: technical note. Eur Spine J. 2009;18:1386-90.
49. Wai EK, Sathiaseelan S, O'Neil J, Simchison BL. Local administration of morphine for analgesia after autogenous anterior or posterior iliac crest bone graft harvest for spinal fusion: a prospective, randomized, double-blind, placebo-controlled study. Anesth Analg. 2010;110:928-33.
50. Morgan SJ, Jeray KJ, Saliman LH, Miller HJ, Williams AE, Tanner SL, Smith WR, Broderick JS. Continuous infusion of local anesthetic at iliac crest bone-graft sites for postoperative pain relief. A randomized, double-blind study. J Bone Joint Surg Am. 2006;88:2606-12. (Pubitemid 44901947)
51. Singh K, Samartzis D, Strom J, Manning D, Campbell-Hupp M, Wetzel FT, Gupta P, Phillips FM. A prospective, randomized, double-blind study evaluating the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after spinal arthrodesis. Spine (Phila Pa 1976). 2005;30:2477-83.
52. Singh K, Phillips FM, Kuo E, Campbell M. A prospective, randomized, double-blind study of the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after posterior spinal arthrodesis: a minimum of 4-year follow-up. Spine (Phila Pa 1976). 2007;32:2790-6.
53. Kurz LT, Garfin SR, Booth RE Jr. Harvesting autogenous iliac bone grafts. A review of complications and techniques. Spine (Phila Pa 1976). 1989;14:1324-31.
54. Sasso RC, Williams JI, Dimasi N, Meyer PR Jr. Postoperative drains at the donor sites of iliac-crest bone grafts. A prospective, randomized study of morbidity at the donor site in patients who had a traumatic injury of the spine. J Bone Joint Surg Am. 1998;80:631-5.
55. Escalas F, DeWald RL. Combined traumatic arteriovenous fistula and ureteral injury: a complication of iliac bone-grafting. J Bone Joint Surg Am. 1977;59:270-1. (Pubitemid 8067272)
56. Herford AS, King BJ, Audia F, Becktor J. Medial approach for tibial bone graft: anatomic study and clinical technique. J Oral Maxillofac Surg. 2003;61:358-63. (Pubitemid 36268384)
57. van Damme PA, Merkx MA. A modification of the tibial bone-graft- harvesting technique. Int J Oral Maxillofac Surg. 1996;25:346-8. (Pubitemid 126327205)
58. Whitehouse MR, Lankester BJ, Winson IG, Hepple S. Bone graft harvest from the proximal tibia in foot and ankle arthrodesis surgery. Foot Ankle Int. 2006;27:913-6. (Pubitemid 44672471)
59. O'Keeffe RM Jr, Riemer BL, Butterfield SL. Harvesting of autogenous cancellous bone graft from the proximal tibial metaphysis. A review of 230 cases. J Orthop Trauma. 1991;5:469-74.
60. Judet H, Gilbert A, Mathoulin C, Judet J, Judet T, Siguier M, Brumpt B. [Reconstruction of loss of bony substance in limbs by free vascularized fibula transplant]. Chirurgie. 1991;117:469-77. French.
61. Catone GA, Reimer BL, McNeir D, Ray R. Tibial autogenous cancellous bone as an alternative donor site in maxillofacial surgery: a preliminary report. J Oral Maxillofac Surg. 1992;50:1258-63.
62. Wang K, Almeida LE, Olsson AB. Volume analysis of the proximal tibial metaphysis. J Oral Maxillofac Surg. 2007;65:2425-9. (Pubitemid 350100971)
63. Gause NL, Ivy A, Myeroff C. Complications associated with proximal tibia bone graft compared to iliac crest bone graft. Presented at the Annual Meeting of the American Academy of Orthopaedic Surgeons. 2010 Mar 9-12; New Orleans, LA.
64. Crenshaw AH. Surgical techniques and approaches. In: Canale ST, Beaty JH. Campbell's operative orthopedics. 11th ed. Philadelphia: Mosby; 2007. p 14-23.
65. Chen YC, Chen CH, Chen PL, Huang IY, Shen YS, Chen CM. Donor site morbidity after harvesting of proximal tibia bone. Head Neck. 2006;28:496-500. (Pubitemid 43846217)
66. Frohberg U, Mazock JB. A review ofmorbidity associated with bone harvest from the proximal tibial metaphysis. Mund Kiefer Gesichtschir. 2005;9:63-5. (Pubitemid 40439342)
67. Geideman W, Early JS, Brodsky J. Clinical results of harvesting autogenous cancellous graft from the ipsilateral proximal tibia for use in foot and ankle surgery. Foot Ankle Int. 2004;25:451-5. (Pubitemid 39096115)
68. Galano GJ, Greisberg JK. Tibial plateau fracture with proximal tibia autograft harvest for foot surgery. Am J Orthop (Belle Mead NJ). 2009;38:621-3.
69. Schuringa MC, Fechner MR. Cancellous bone grafting from the distal radius. Eur J Plast Surg. 2002;25:319-22. (Pubitemid 36097681)
70. Horne LT, Murray PM, Saha S, Sidhar K. Effects of distal radius bone graft harvest on the axial compressive strength of the radius. J Hand Surg. 2010;35:262-6.
71. Jarrett P, Kinzel V, Stoffel K. A biomechanical comparison of scaphoid fixation with bone grafting using iliac bone or distal radius bone. J Hand Surg Am. 2007;32:1367-73. (Pubitemid 350051582)
72. Mirly HL, Manske PR, Szerzinski JM. Distal anterior radius bone graft in surgery of the hand and wrist. J Hand Surg Am. 1995;20:623-7.
73. Biddulph SL. Bone donor site. Iliac crest or distal radius? J Hand Surg Br. 1999;24:645-6. (Pubitemid 30037837)
74. Saltrick KR, Caron M, Grossman J. Utilization of autogenous corticocancellous bone graft from the distal tibia for reconstructive surgery of the foot and ankle. J Foot Ankle Surg. 1996;35:406-12. (Pubitemid 26378156)
75. Weiss GA, Saxby TS. Distal tibial bone graft for foot and ankle surgery. Foot Ankle Surg. 1998;4:93-7. (Pubitemid 29304664)
76. Lindberg EJ, Katchis SD, Smith RW. Quantitative analysis of cancellous bone graft available from the greater trochanter. Foot Ankle Int. 1996;17:473-6. (Pubitemid 26282301)
77. Hayes WR Jr, Smith RW. Trochanteric bone grafts in foot and ankle surgery. Foot Ankle Int. 1996;17:402-5. (Pubitemid 26256021)
78. Pape HC, Auf'm'Kolk M, Paffrath T, Regel G, Sturm JA, Tscherne H. Primary intramedullary femur fixation in multiple trauma patients with associated lung contusion-a cause of posttraumatic ARDS? J Trauma. 1993:34:540-8.
79. Roberts CS, Pape HC, Jones AL, Malkani AL, Rodriguez JL, Giannoudis PV. Damage control orthopaedics: evolving concepts in the treatment of patients who have sustained orthopaedic trauma. J Bone Joint Surg Am. 2005;87:434-49. (Pubitemid 40216647)
80. McCall TA, Brokaw DS, Jelen BA, Scheid DK, Scharfenberger AV, Maar DC, Green JM, Shipps MR, Stone MB, Musapatika D, Weber TG. Treatment of large segmental bone defects with reamer-irrigator-aspirator bone graft: technique and case series. Orthop Clin North Am. 2010;41:63-73.
81. Husebye EE, Lyberg T, Madsen JE, Eriksen M, Røise O. The influence of a one-step reamer-irrigator-aspirator technique on the intramedullary pressure in the pig femur. Injury. 2006;37:935-40. (Pubitemid 44311136)
82. Quintero AJ, Tarkin IS, Pape HC. Technical tricks when using the reamer irrigator aspirator technique for autologous bone graft harvesting. J Orthop Trauma. 2010;24:42-5.
83. Scharfenberger AV, Weber TG. Reamer irrigator aspirator (RIA) for bone graft harvest: applications for grafting large segmental defects in the tibia and femur. J Bone Joint Surg Br. Proceedings. 2008;90:95.
84. Lowe JA, Della Rocca GJ, Murtha Y, Liporace FA, Stover MD, Nork SE, Crist BD. Complications associated with negative pressure reaming for harvesting autologous bone graft: a case series. J Orthop Trauma. 2010;24:46-52.
85. Sagi CH, Young M, Gerstenfeld L, Shah AR, Tornetta P. Quantitative differences between bone graft obtained with a reamer/irrigator/aspirator and from the iliac crest. Presented at the Orthopaedic Trauma Association Annual Meeting; 2009 Oct 7-10; San Diego, CA.
86. Porter RM, Liu F, Pilapil C, Betz OB, Vrahas MS, Harris MB, Evans CH. Osteogenic potential of reamer irrigator aspirator (RIA) aspirate collected from patients undergoing hip arthroplasty. J Orthop Res. 2009;27:42-9.
87. Finnan RP, Prayson MJ, Goswami T, Miller D. Use of the Reamer-Irrigator-Aspirator for bone graft harvest: a mechanical comparison of three starting points in cadaveric femurs. J Orthop Trauma. 2010;24:36-41.
88. Pratt DJ, Papagiannopoulos G, Rees PH, Quinnell R. The effects of medullary reaming on the torsional strength of the femur. Injury. 1987;18:177-9. (Pubitemid 17074137)
89. Conway JD. Autograft and nonunions: morbidity with intramedullary bone graft versus iliac crest bone graft. Orthop Clin North Am. 2010;41:75-84.
90. Masquelet AC, Begue T. The concept of induced membrane for reconstruction of long bone defects. Orthop Clin North Am. 2010;41:23-37.
91. Biau DJ, Pannier S, Masquelet AC, Glorion C. Case report: reconstruction of a 16-cm diaphyseal defect after Ewing's resection in a child. Clin Orthop Relat Res. 2009;467:572-7.
92. DeCoster TA, Gehlert RJ, Mikola EA, Pirela-Cruz MA. Management of posttraumatic segmental bone defects. J Am Acad Orthop Surg. 2004;12:28-38.
93. Pelissier P, Masquelet AC, Bareille R, Pelissier SM, Amedee J. Induced membranes secrete growth factors including vascular and osteoinductive factors and could stimulate bone regeneration. J Orthop Res. 2004;22:73-9. (Pubitemid 38043892)
94. Papineau LJ. [Excision-graft with deliberately delayed closing in chronic osteomyelitis]. Nouv Presse Med. 1973;2:2753-5. French.
95. Huffman LK, Harris JG, Suk M. Using the bi-masquelet technique and reamer-irrigator-aspirator for post-traumatic foot reconstruction. Foot Ankle Int. 2009;30:895-9.