The Effectiveness of Anti-leukotriene Agents in Patients with COPD: A Systemic Review and Meta-analysis

Lung

Volumn 193, Issue 4, 2015, Pages 477-486

  Lee, Jong Hoo ^a   Kim, Hyun Jung ^b   Kim, Yee Hyung ^c  

^a Jeju National University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Kyung Hee University College of Medicine   (South Korea)

Author keywords

Anti leukotriene modifiers; Chronic obstructive pulmonary disease; Leukotrienes; Treatment

Indexed keywords

LEUKOTRIENE B4; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MYELOPEROXIDASE; PEROXIDASE;

ARTICLE; BRONCHODILATATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL (TOPIC); DRUG EFFICACY; DYSPNEA; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SPUTUM; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT RESPONSE; BLOOD; DRUG EFFECTS; OXYGEN THERAPY; PATHOPHYSIOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; VITAL CAPACITY;

DYSPNEA; FORCED EXPIRATORY VOLUME; HUMANS; LEUKOTRIENE ANTAGONISTS; OXYGEN INHALATION THERAPY; PEROXIDASE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SPUTUM; VITAL CAPACITY;

EID: 84937518828     PISSN: 03412040     EISSN: 14321750     Source Type: Journal    
DOI: 10.1007/s00408-015-9743-5     Document Type: Article

References (37)

1. Riccioni G, Bucciarelli T, Mancini B et al (2007) Antileukotriene drugs: clinical application, effectiveness and safety. Curr Med Chem 14:1966–1977
2. Manning PJ, Watson RM, Margolskee DJ et al (1990) Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist. N Engl J Med 323:1736–1739. doi:10.1056/NEJM199012203232504
3. Tohda Y, Nakahara H, Kubo H et al (1999) Effects of ONO-1078 (pranlukast) on cytokine production in peripheral blood mononuclear cells of patients with bronchial asthma. Clin Exp Allergy 29:1532–1536
4. Peters-Golden M, Henderson WR Jr (2007) Leukotrienes. N Engl J Med 357:1841–1854. doi:10.1056/NEJMra071371
5. Global Initiative for Asthma (GINA) (2015) GINA Report, Global Strategy for Asthma Management and Prevention. http://www.ginasthma.org/. Accessed 12 Feb 2015
6. Chung KF, Wenzel SE, Brozek JL et al (2014) International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Resp J 43:343–373. doi:10.1183/09031936.00202013
7. Kennedy-Feitosa E, Pinto RF, Pires KM et al (2014) The influence of 5-lipoxygenase on cigarette smoke-induced emphysema in mice. Biochim Biophys Acta 1840:199–208. doi:10.1016/j.bbagen.2013.09.028
8. Ikeda G, Miyahara N, Koga H et al (2014) A effect of a cysteinyl leukotriene receptor antagonist on experimental emphysema and asthma combined with emphysema. Am J Respir Cell Mol Biol 50:18–29. doi:10.1165/rcmb.2012-0418OC
9. Tufvesson E, Ekberg M, Bjermer L (2013) Inflammatory biomarkers in sputum predict COPD exacerbations. Lung 191:413–416. doi:10.1007/s00408-013-9473-5
10. Drozdovszky O, Barta I, Antus B (2014) Sputum eicosanoid profiling in exacerbations of chronic obstructive pulmonary disease. Respiration 87:408–415. doi:10.1159/000358099
11. Papaiwannou A, Zarogoulidis P, Porpodis K et al (2014) Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): current literature review. J Thorac Dis 6:S146–S151. doi:10.3978/j.issn.2072-1439.2014.03.04
12. Vogelmeier C, Hederer B, Glaab T et al (2011) Tiotropium versus salmeterol for the prevention of exacerbations of COPD. N Engl J Med 364:1093–1103. doi:10.1056/NEJMoa1008378
13. Kerstjens HA, Engel M, Dahl R et al (2012) Tiotropium in asthma poorly controlled with standard combination therapy. N Engl J Med 367:1198–1207. doi:10.1056/NEJMoa1208606
14. Lee SW, Kim HJ, Yoo KH et al (2014) Long-acting anticholinergic agents in patients with uncontrolled asthma: a systematic review and meta-analysis. Int J Tuberc Lung Dis 18:1421–1430. doi:10.5588/ijtld.14.0275
15. Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2015) Global Strategy for the Diagnosis, Management, and Prevention of COPD. http://www.goldcopd.org/. Accessed 12 Feb 2015
16. Woodruff PG, Albert RK, Bailey WC et al (2011) Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization. COPD 8:21–29. doi:10.3109/15412555.2010.540273
17. Gronke L, Beeh KM, Cameron R et al (2008) Effect of the oral leukotriene B4 receptor antagonist LTB019 on inflammatory sputum markers in patients with chronic obstructive pulmonary disease. Pulm Pharmacol Ther 21:409–417. doi:10.1016/j.pupt.2007.10.007
18. Celik P, Sakar A, Havlucu Y et al (2005) Short-term effects of montelukast in stable patients with moderate to severe COPD. Respir Med 99:444–450. doi:10.1016/j.rmed.2004.09.008
19. Gompertz S, Stockley RA (2002) A randomized, placebo-controlled trial of a leukotriene synthesis inhibitor in patients with COPD. Chest 122:289–294
20. Moosavi SA, Raji H, Tasorian B et al (2013) Effect of Zafirlukast on improving lung function in patients with chronic obstructive pulmonary diseases. Med J Islam Repub Iran 27:57–61
21. Gueli N, Verrusio W, Linguanti A et al (2011) Montelukast therapy and psychological distress in chronic obstructive pulmonary disease (COPD): a preliminary report. Arch Gerontol Geriatr 52:e36–e39. doi:10.1016/j.archger.2010.04.014
22. Rubinstein I, Kumar B, Schriever C (2004) Long-term montelukast therapy in moderate to severe COPD–a preliminary observation. Respir Med 98:134–138
23. Dempsey OJ, Wilson AM, Sims EJ et al (2000) Additive bronchoprotective and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids. Chest 117:950–953
24. Zuhlke IE, Kanniess F, Richter K et al (2003) Montelukast attenuates the airway response to hypertonic saline in moderate-to-severe COPD. Eur Respir J 22:926–930
25. National Asthma Education and Prevention Program (2007) Expert Panel Report 3 (EPR-3): guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol 120:S94–S138. doi:10.1016/j.jaci.2007.09.043
26. Drakatos P, Lykouras D, Sampsonas F et al (2009) Targeting leukotrienes for the treatment of COPD? Inflamm Allergy Drug Targets 8:297–306
27. Kostikas K, Gaga M, Papatheodorou G et al (2005) Leukotriene B4 in exhaled breath condensate and sputum supernatant in patients with COPD and asthma. Chest 127:1553–1559. doi:10.1378/chest.127.5.1553
28. Montuschi P, Kharitonov SA, Ciabattoni G et al (2003) Exhaled leukotrienes and prostaglandins in COPD. Thorax 58:585–588
29. Biernacki WA, Kharitonov SA, Barnes PJ (2003) Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD. Thorax 58:294–298
30. Beeh KM, Kornmann O, Buhl R et al (2003) Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4. Chest 123:1240–1247
31. Furukawa T, Sakagami T, Koya T et al (2014) Characteristics of eosinophilic and non-eosinophilic asthma during treatment with inhaled corticosteroids. J Asthma. doi:10.3109/02770903.2014.975357
32. Telenga ED, Kerstjens HA, Ten Hacken NH et al (2013) Inflammation and corticosteroid responsiveness in ex-, current- and never-smoking asthmatics. BMC Pulm Med 13:58. doi:10.1186/1471-2466-13-58
33. Price D, Popov TA, Bjermer L et al (2013) Effect of montelukast for treatment of asthma in cigarette smokers. J Allergy Clin Immunol 131:763–771. doi:10.1016/j.jaci.2012.12.673
34. Zhu J, Bandi V, Qiu S, Figueroa DJ et al (2012) Cysteinyl leukotriene 1 receptor expression associated with bronchial inflammation in severe exacerbations of COPD. Chest 142:347–357. doi:10.1378/chest.11-1581
35. Papi A, Romagnoli M, Baraldo S et al (2000) Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 162:1773–1777. doi:10.1164/ajrccm.162.5.9910112
36. Fauler J, Frolich JC (1997) Cigarette smoking stimulates cysteinyl leukotriene production in man. Eur J Clin Invest 27:43–47
37. Hernandez-Alvidrez E, Alba-Reyes G, Munoz-Cedillo BC et al (2013) Passive smoking induces leukotriene production in children: influence of asthma. J Asthma 50:347–353. doi:10.3109/02770903.2013.773009