Effect of the oral leukotriene B4 receptor antagonist LTB019 on inflammatory sputum markers in patients with chronic obstructive pulmonary disease

Pulmonary Pharmacology and Therapeutics

Volumn 21, Issue 2, 2008, Pages 409-417

  Gronke L ^a   Beeh, K M ^b,c   Cameron, R ^d   Kornmann, O ^b   Beier, J ^b,c   Shaw, M ^d   Holz, O ^a   Buhl, R ^b   Magnussen, H ^a   Jorres R A ^a,e  

^a KRANKENHAUS GROSSHANSDORF   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c Institut fur Atemwegsforschung INSAF   (Germany)

^d Novartis Pharma   (United Kingdom)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

Airway obstruction; COPD; Induced sputum; Leukotriene B4; Neutrophils; Receptor antagonist

Indexed keywords

INTERLEUKIN 8; LEUKOTRIENE B4 RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LTB 019; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ANALYSIS OF COVARIANCE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MALE; NEUTROPHIL; NEUTROPHIL COUNT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPUTUM ANALYSIS; TREATMENT DURATION; UPREGULATION;

AGED; BENZAMIDES; BIOLOGICAL MARKERS; CROSS-OVER STUDIES; CYTOKINES; DOUBLE-BLIND METHOD; EOSINOPHILS; FEMALE; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, LEUKOTRIENE B4; RESPIRATORY FUNCTION TESTS; SPUTUM;

EID: 39749178346     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2007.10.007     Document Type: Article

References (37)