An indicator-guided photo-controlled drug delivery system based on mesoporous silica/gold nanocomposites

Nano Research

Volumn 8, Issue 6, 2015, Pages 1893-1905

  Luo, Guofeng ^a   Chen, Weihai ^a   Jia, Huizhen ^a   Sun, Yunxia ^a   Cheng, Han ^a   Zhuo, Renxi ^a   Zhang, Xianzheng ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

drug delivery; MMP 2 sensitive; MSN Au nanocomposite; photo controlled; tumor therapy

Indexed keywords

EID: 84937518074     PISSN: 19980124     EISSN: 19980000     Source Type: Journal    
DOI: 10.1007/s12274-014-0698-2     Document Type: Article

References (62)

1. He, Q.; Shi, J. MSN anti-cancer nanomedicines: Chemotherapy enhancement, overcoming of drug resistance, and metastasis inhibition. Adv. Mater.2014, 26, 391–411.
2. Ambrogio, M. W.; Thomas, C. R.; Zhao, Y. L.; Zink, J. I.; Stoddart, J. F. Mechanized silica nanoparticles: A new frountier in theranostic nanomedicine. Acc. Chem. Res.2011, 44, 903–913.
3. Wu, S. H.; Hung, Y.; Mou, C. Y. Mesoporous silica nanoparticles as nanocarriers. Chem. Commun.2011, 47, 9972–9985.
4. Tang, F.; Li, L.; Chen, D. Mesoporous silica nanoparticles: Synthesis, biocompatibility and drug delivery. Adv. Mater.2012, 24, 1504–1534.
5. Popat, A.; Hartono, S. B.; Stahr, F.; Liu, J.; Qiao, S. Z.; Qing Max Lu, G. Mesoporous silica nanoparticles for bioadsorption, enzyme immobilization, and delivery carriers. Nanoscale2011, 3, 2801–2818.
6. Yang, P.; Gai, S.; Lin, J. Functionalized mesoporous silica materials for controlled drug delivery. Chem. Soc. Rev.2012, 41, 3679–3698.
7. Chen, Y.; Chen, H.; Shi, J. In vivo bio-safety evaluations and diagnostic/therapeutic applications of chemically designed mesoporous silica nanoparticles. Adv. Mater.2013, 25, 3144–3176.
8. Chen, A. M.; Zhang, M.; Wei, D.; Stueber, D.; Taratula, O.; Minko, T.; He, H. Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells. Small2009, 5, 2673–2677.
9. Guardado-Alvarez, T. M.; Sudha Devi, L.; Russell, M. M.; Schwartz, B. J.; Zink, J. I. Activation of snap-top capped mesoporous silica nanocontainers using two near-infrared photons. J. Am. Chem. Soc.2013, 135, 14000–14003.
10. Mei, X.; Yang, S.; Chen, D.; Li, N.; Li, H.; Xu, Q.; Ge, J.; Lu, J. Light-triggered reversible assemblies of azobenzene-containing amphiphilic copolymer with β-cyclodextrin-modified hollow mesoporous silica nanoparticles for controlled drug release. Chem. Commun.2012, 48, 10010–10012.
11. Qian, R.; Ding, L.; Ju, H. Switchable fluorescent imaging of intracellular telomerase activity using telomerase-responsive mesoporous silica nanoparticle. J. Am. Chem. Soc.2013, 135, 13282–13285.
12. Zhu, C. L.; Lu, C. H.; Song, X. Y.; Yang, H. H.; Wang, X. R. Bioresponsive controlled release using mesoporous silica nanoparticles capped with aptamer-based molecular gate. J. Am. Chem. Soc.2011, 133, 1278–1281.
13. Yan, H.; Teh, C.; Sreejith, S.; Zhu, L.; Kwok, A.; Fang, W.; Ma, X.; Nguyen, K. T.; Korzh, V.; Zhao, Y. Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew. Chem. Int. Ed.2012, 51, 8373–8377.
14. Díez, P.; Sánchez, A.; Gamella, M.; Martínez-Ruíz, P.; Aznar, E.; de la Torre, C.; Murguía, J. R.; Martínez-Máñez, R.; Villalonga, R.; Pingarrón, J. M. Toward the design of smart delivery systems controlled by integrated enzyme-based biocomputing ensembles. J. Am. Chem. Soc.2014, 136, 9116–9123.
15. Yang, K. N.; Zhang, C. Q.; Wang, W.; Wang, P. C.; Zhou, J. P.; Liang, X. J. pH-responsive mesoporous silica nanoparticles employed in controlled drug delivery systems for cancer treatment. Cancer Biol. Med.2014, 11, 34–43.
16. Muhammad, F.; Guo, M.; Qi, W.; Sun, F.; Wang, A.; Guo, Y.; Zhu, G. pH-triggered controlled drug release from mesoporous silica nanoparticles via intracellular dissolution of ZnO nanolids. J. Am. Chem. Soc.2011, 133, 8778–8781.
17. Fu, J.; Chen, T.; Wang, M.; Yang, N.; Li, S.; Wang, Y.; Liu, X. Acid and alkaline dual stimuli-responsive mechanized hollow mesoporous silica nanoparticles as smart nanocontainers for intelligent anticorrosion coating. ACS Nano2013, 7, 11397–11408.
18. Xiao, D.; Jia, H. Z.; Zhang, J.; Liu, C. W.; Zhuo, R. X.; Zhang, X. Z. A dual-responsive mesoporous silica nanoparticle for tumor-triggered targeting drug delivery. Small2014, 10, 591–598.
19. Zhang, Q.; Liu, F.; Nguyen, K. T.; Ma, X.; Wang, X.; Xing, B.; Zhao, Y. Multifunctional mesoporous silica nanoparticles for cancer-targeted and controlled drug delivery. Adv. Funct. Mater.2012, 22, 5144–5156.
20. Wang, A.; Guo, M.; Wang, N.; Zhao, J.; Qi, W.; Muhammad, F.; Chen, L.; Guo, Y.; Nguyen, N. T.; Zhu, G. Redox-mediated dissolution of paramagnetic nanolids to achieve a smart theranostic system. Nanoscale2014, 6, 5270–5278.
21. Kim, H.; Kim, S.; Park, C.; Lee, H.; Park, H. J.; Kim, C. Glutathione-induced intracellular release of guests from mesoporous silica nanocontainers with cyclodextrin gatekeepers. Adv. Mater.2010, 22, 4280–4283.
22. Nadrah, P.; Maver, U.; Jemec, A.; Tišler, T.; Bele, M.; Dražić, G.; Benčina, M.; Pintar, A.; Planinšek, O.; Gaberšček, M. Hindered disulfide bonds to regulate release rate of model drug from mesoporous silica. ACS Appl. Mater. Interfaces2013, 5, 3908–3915.
23. Frasconi, M.; Liu, Z.; Lei, J.; Wu, Y.; Strekalova, E.; Malin, D.; Ambrogio, M. W.; Chen, X.; Botros, Y. Y.; Cryns, V. L. et al. Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles. J. Am. Chem. Soc.2013, 135, 11603–11613.
24. Croissant, J.; Maynadier, M.; Gallud, A.; Peindy N’dongo, H.; Nyalosaso, J. L.; Derrien, G.; Charnay, C.; Durand, J. O.; Raehm, L.; Serein-Spirau, F. et al. Two-photon-triggered drug delivery in cancer cells using nanoimpellers. Angew. Chem. Int. Ed.2013, 52, 13813–13817.
25. Wen, Y.; Xu, L.; Wang, W.; Wang, D.; Du, H.; Zhang, X. Highly efficient remote controlled release system based on light-driven DNA nanomachine functionalized mesoporous silica. Nanoscale2012, 4, 4473–4476.
26. Sun, Y. L.; Zhou, Y.; Li, Q. L.; Yang, Y. W. Enzyme-responsive supramolecular nanovalves crafted by mesoporous silica nanoparticles and cholinesulfonatocalix[4]arene [2]pseudorotaxanes for controlled cargo release. Chem. Commun.2013, 49, 9033–9035.
27. Agostini, A.; Mondragón, L.; Bernardos, A.; Martínez-Máñez, R.; Marcos, M. D.; Sancenón, F.; Soto, J.; Costero, A.; Manguan-García, C.; Perona, R.; Moreno-Torres, M.; Aparicio-Sanchis, R.; Murguía, J. R. Targeted cargo delivery in senescent cells using capped mesoporous silica nanoparticles. Angew. Chem. Int. Ed.2012, 51, 10556–10560.
28. De la Torre, C.; Agostini, A.; Mondragón, L.; Orzáez, M.; Sancenón, F.; Martínez-Máñez, R.; Marcos, M. D.; Amorós, P.; Pérez-Payá, E. Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports. Chem. Commun.2014, 50, 3184–3186.
29. Climent, E.; Martínez-Máñez, R.; Sancenón, F.; Marcos, M. D.; Soto, J.; Maquieira, A.; Amorós, P. Controlled delivery using oligonucleotide-capped mesoporous silica nanoparticles. Angew. Chem. Int. Ed.2010, 49, 7281–7283.
30. Yuan, Q.; Zhang, Y.; Chen, T.; Lu, D.; Zhao, Z.; Zhang, X.; Li, Z.; Yan, C. H.; Tan, W. Photo-manipulated drug release from a mesoporous nanocontainer controlled by azobenzene-modified nucleic acid. ACS Nano2012, 6, 6337–6344.
31. Mal, N. K.; Fujiwara, M.; Tanaka, Y. Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica. Nature2003, 421, 350–353.
32. Lu, J.; Choi, E.; Tamanoi, F.; Zink, J. I. Light-activated nanoimpeller-controlled drug release in cancer cells. Small2008, 4, 421–426.
33. Ferris, D. P.; Zhao, Y. L.; Khashab, N. M.; Khatib, H. A.; Stoddart, J. F.; Zink, J. I. Light-operated mechanized nanoparticles. J. Am. Chem. Soc.2009, 131, 1686–1688.
34. Park, C.; Lee, K.; Kim, C. Photoresponsive cyclodextrin-covered nanocontainers and their sol-gel transition induced by molecular recognition. Angew. Chem. Int. Ed.2009, 48, 1275–1278.
35. Vivero-Escoto, J. L.; Slowing, I. I.; Wu, C. W.; Lin, V. S. Photoinduced intracellular controlled release drug delivery in human cells by gold-capped mesoporous silica nanosphere. J. Am. Chem. Soc.2009, 131, 3462–3463.
36. Kessenbrock, K.; Plaks, V.; Werb, Z. Matrix metalloproteinases: Regulators of the tumor microenvironment. Cell2010, 141, 52–67.
37. Jiang, T.; Olson, E. S.; Nguyen, Q. T.; Roy, M.; Jennings, P. A.; Tsien, R. Y. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc. Natl. Acad. Sci. USA2004, 101, 17867–17872.
38. Zhang, X. X.; Eden, H. S.; Chen, X. Peptides in cancer nanomedicine: Drug carriers, targeting ligands and protease substrates. J. Controlled Release2012, 159, 2–13.
39. Egeblad, M.; Werb, Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer2002, 2, 161–174.
40. Andresen, T. L.; Thompson, D. H.; Kaasgaard, T. Enzyme-triggered nanomedicine: Drug release strategies in cancer therapy. Mol. Membr. Biol.2010, 27, 353–363.
41. Merdad, A.; Karim, S.; Schulten, H. J.; Dallol, A.; Buhmeida, A.; Al-Thubaity, F.; Gari, M. A.; Chaudhary, A. G.; Abuzenadah, A. M.; Al-Qahtani, M. H. Expression of matrix metalloproteinases (MMPs) in primary human breast cancer: MMP-9 as a potential biomarker for cancer invasion and metastasis. Anticancer Res.2014, 34, 1355–1366.
42. Garripelli, V. K.; Kim, J. K.; Son, S.; Kim, W. J.; Repka, M. A.; Jo, S. Matrix metalloproteinase-sensitive thermogelling polymer for bioresponsive local drug delivery. Acta Biomater.2011,7,1984–1992.
43. Sarkar, N. R.; Rosendahl, T.; Krueger, A. B.; Banerjee, A. L.; Benton, K.; Mallik, S.; Srivastava, D. K. “Uncorking” of liposomes by matrix metalloproteinase-9. Chem. Commun.2005, 8, 999–1001.
44. Elegbede, A. I.; Banerjee, J.; Hanson, A. J.; Tobwala, S.; Ganguli, B.; Wang, R.; Lu, X.; Srivastava, D. K.; Mallik, S. Mechanistic studies of the triggered release of liposomal contents by matrix metalloproteinase-9. J. Am. Chem. Soc.2008, 130, 10633–10642.
45. Sun, I. C.; Eun, D. K.; Koo, H.; Ko, C. Y.; Kim, H. S.; Yi, D. K.; Choi, K.; Kwon, I. C.; Kim, K.; Ahn, C. H. Tumor-targeting gold particles for dual computed tomography/optical cancer imaging. Angew. Chem. Int. Ed.2011, 50, 9348–9351.
46. Myochin, T.; Hanaoka, K.; Komatsu, T.; Terai, T.; Nagano, T. Design strategy for a near-infrared fluorescence probe for matrix metalloproteinase utilizing highly cell permeable boron dipyrromethene. J. Am. Chem. Soc.2012, 134, 13730–13737.
47. Xu, J. H.; Gao, F. P.; Liu, X. F.; Zeng, Q.; Guo, S. S.; Tang, Z. Y.; Zhao, X. Z.; Wang, H. Supramolecular gelatin nanoparticles as matrix metalloproteinase responsive cancer cell imaging probes. Chem. Commun.2013, 49, 4462–4464.
48. Ryu, J. H.; Shin, J. Y.; Kim, S. A.; Kang, S. W.; Kim, H.; Kang, S.; Choi, K.; Kwon, I. C.; Kim, B. S.; Kim, K. Non-invasive optical imaging of matrix metalloproteinase activity with albumin-based fluorogenic nanoprobes during angiogenesis in a mouse hindlimb ischemia model. Biomaterials2013, 34, 6871–6881.
49. Chen, P.; Selegård, R.; Aili, D.; Liedberg, B. Peptide functionalized gold nanoparticles for colorimetric detection of matrilysin (MMP-7) activity. Nanoscale2013, 5, 8973–8976.
50. Kim, J. H.; Chung, B. H. Proteolytic fluorescent signal amplification on gold nanoparticles for a highly sensitive and rapid protease assay. Small2010, 6, 126–131.
51. Lee, S.; Cha, E. J.; Park, K.; Lee, S. Y.; Hong, J. K.; Sun, I. C.; Kim, K.; Ahn, C. H. A near-infrared-fluorescence-quenched gold-nanoparticle imaging probe for in vivo drug screening and protease activity determination. Angew. Chem. Int. Ed.2008, 47, 2804–2807.
52. Zhang, J.; Yuan, Z. F.; Wang, Y.; Chen, W. H.; Luo, G. F.; Cheng, S. X.; Zhuo, R. X.; Zhang, X. Z. Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery. J. Am. Chem. Soc.2013, 135, 5068–5073.
53. Rekharsky, M. V.; Inoue, Y. Complexation thermodynamics of cyclodextrins. Chem. Rev.1998, 98, 1875–1918.
54. Liu, R.; Zhang, Y.; Zhao, X.; Agarwal, A.; Mueller, L. J.; Feng, P. pH-responsive nanogated ensemble based on gold-capped mesoporous silica through an acid-labile acetal linker. J. Am. Chem. Soc.2010, 132, 1500–1501.
55. Lee, H.; Lee, K.; Kim, I. K.; Park, T. G. Synthesis, characterization, and in vivo diagnostic applications of hyaluronic acid immobilized gold nanoprobes. Biomaterials2008, 29, 4709–4718.
56. Kang, B.; Afifi, M. M.; Austin, L. A.; El-Sayed, M. A. Exploiting the nanoparticle plasmon effect: Observing drug delivery dynamics in single cells via Raman/fluorescence imaging spectroscopy. ACS Nano2013, 7, 7420–7427.
57. Chen, W. H.; Xu, X. D.; Jia, H. Z.; Lei, Q.; Luo, G. F.; Cheng, S. X.; Zhuo, R. X.; Zhang, X. Z. Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo. Biomaterials2013, 34, 8798–8807.
58. Xiao, W.; Chen, W. H.; Xu, X. D.; Li, C.; Zhang, J.; Zhuo, R. X.; Zhang, X. Z. Design of a cellular-uptake-shielding “plug and play” template for photo controllable drug release. Adv. Mater.2011, 23, 3526–3530.
59. Dugave, C.; Demange, L. Cis-trans isomerization of organic molecules and biomolecules: Implications and applications. Chem. Rev.2003, 103, 2475–2532.
60. Luo, G. F.; Chen, W. H.; Liu, Y.; Zhang, J.; Cheng, S. X.; Zhuo, R. X.; Zhang, X. Z. Charge-reversal plug gate nanovalves on peptide-functionalized mesoporous silica nanoparticles for targeted drug delivery. J. Mater. Chem. B2013, 1, 5723–5732.
61. Fields, G. B.; Noble, R. L. Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. Int. J. Pept. Protein Res.1990, 35, 161–214.
62. Pan, L.; He, Q.; Liu, J.; Chen, Y.; Ma, M.; Zhang, L.; Shi, J. Nuclear-targeted drug delivery of TAT peptide-conjugated monodisperse mesoporous silica nanoparticles. J. Am. Chem. Soc.2012, 134, 5722–5725.