Two chalcones, 4-hydroxyderricin and xanthoangelol, stimulate GLUT4-dependent glucose uptake through the LKB1/AMP-activated protein kinase signaling pathway in 3T3-L1 adipocytes

Nutrition Research

Volumn 35, Issue 7, 2015, Pages 618-625

  Ohta, Mitsuhiro ^a   Fujinami, Aya ^a   Kobayashi, Norihiro ^a   Amano, Akiko ^b   Ishigami, Akihito ^b   Tokuda, Harukuni ^c   Suzuki, Nobutaka ^c   Ito, Fumitake ^d   Mori, Taisuke ^d   Sawada, Morio ^d   Iwasa, Koichi ^d   Kitawaki, Jo ^d   Ohnishi, Katsunori ^e   Tsujikawa, Muneo ^f   Obayashi, Hiroshi ^f  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^d KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^e Japan Bio Science Laboratory   (Japan)

^f Inst of Bio Response Informatics   (Japan)

Author keywords

4 Hydroxyderricin; Chalcones; Glucose uptake; GLUT4; LKB1 AMPK signaling; Xanthoangelol

Indexed keywords

4 HYDROXYDERRICIN; ACETYL COENZYME A CARBOXYLASE; ANGELICA KEISKEI EXTRACT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE I; GLUCOSE; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIVER KINASE B1; PHOSPHOTRANSFERASE; PLANT EXTRACT; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; XANTHOANGELOL; 4-HYDROXYDERRICIN; CHALCONE; CHALCONE DERIVATIVE; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, MOUSE;

3T3 CELL LINE; ADIPOCYTE; ANGELICA; ANGELICA KEISKEI; ARTICLE; CELL MEMBRANE TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; DRUG PURIFICATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GLUCOSE TRANSPORT; MEDICINAL PLANT; PLANT STEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG EFFECTS; METABOLISM; MOUSE; PHOSPHORYLATION;

ANGELICA KEISKEI;

3T3-L1 CELLS; ADIPOCYTES; AMP-ACTIVATED PROTEIN KINASES; ANGELICA; ANIMALS; CHALCONE; CHALCONES; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; MICE; PHOSPHORYLATION; PLANT EXTRACTS; PLANT STEMS; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84937513098     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2015.05.010     Document Type: Article

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