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Volumn 290, Issue 29, 2015, Pages 18068-18078

In vivo and in vitro evidence for biochemical coupling of reactions catalyzed by lysophosphatidylcholine acyltransferase and diacylglycerol acyltransferase

Author keywords

[No Author keywords available]

Indexed keywords

FLAX; GLYCEROL; LINEN; OILSEEDS; PHOSPHOLIPIDS; POLYUNSATURATED FATTY ACIDS; YEAST;

EID: 84937485181     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.654798     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 0029328579 scopus 로고
    • Lipid biosynthesis
    • Ohlrogge, J., and Browse, J. (1995) Lipid biosynthesis. Plant Cell 7, 957-970
    • (1995) Plant Cell , vol.7 , pp. 957-970
    • Ohlrogge, J.1    Browse, J.2
  • 2
    • 0027716681 scopus 로고
    • In vivo desaturation of cis-Δ9-monounsaturated to cis-Δ9,12-diunsaturated alkenylether glycerolipids
    • Sperling, P., Linscheid, M., Stöcker, S., Mühlbach, H. P., and Heinz, E. (1993) In vivo desaturation of cis-Δ9-monounsaturated to cis-Δ9,12-diunsaturated alkenylether glycerolipids. J. Biol. Chem. 268, 26935-26940
    • (1993) J. Biol. Chem. , vol.268 , pp. 26935-26940
    • Sperling, P.1    Linscheid, M.2    Stöcker, S.3    Mühlbach, H.P.4    Heinz, E.5
  • 4
    • 0034612345 scopus 로고    scopus 로고
    • Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
    • Dahlqvist, A., Stahl, U., Lenman, M., Banas, A., Lee, M., Sandager, L., Ronne, H., and Stymne, S. (2000) Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants. Proc. Natl. Acad. Sci. U.S.A. 97, 6487-6492
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 6487-6492
    • Dahlqvist, A.1    Stahl, U.2    Lenman, M.3    Banas, A.4    Lee, M.5    Sandager, L.6    Ronne, H.7    Stymne, S.8
  • 5
    • 84882315826 scopus 로고    scopus 로고
    • Identification of a pair of phospholipid: Diacylglycerol acyltransferases from developing flax (Linum usitatissimum L.) seed catalyzing the selective production of trilinolenin
    • Pan, X., Siloto, R. M., Wickramarathna, A. D., Mietkiewska, E., and Weselake, R. J. (2013) Identification of a pair of phospholipid: diacylglycerol acyltransferases from developing flax (Linum usitatissimum L.) seed catalyzing the selective production of trilinolenin. J. Biol. Chem. 288, 24173-24188
    • (2013) J. Biol. Chem. , vol.288 , pp. 24173-24188
    • Pan, X.1    Siloto, R.M.2    Wickramarathna, A.D.3    Mietkiewska, E.4    Weselake, R.J.5
  • 6
    • 79958800838 scopus 로고    scopus 로고
    • Endoplasmic reticulum-located PDAT1-2 from castor bean enhances hydroxy fatty acid accumulation in transgenic plants
    • Kim, H. U., Lee, K. R., Go, Y. S., Jung, J. H., Suh, M. C., and Kim, J. B. (2011) Endoplasmic reticulum-located PDAT1-2 from castor bean enhances hydroxy fatty acid accumulation in transgenic plants. Plant Cell Physiol. 52, 983-993
    • (2011) Plant Cell Physiol. , vol.52 , pp. 983-993
    • Kim, H.U.1    Lee, K.R.2    Go, Y.S.3    Jung, J.H.4    Suh, M.C.5    Kim, J.B.6
  • 7
    • 79551702015 scopus 로고    scopus 로고
    • Castor phospholipid:diacylglycerol acyltransferase facilitates efficient metabolism of hydroxy fatty acids in transgenic Arabidopsis
    • van Erp, H., Bates, P. D., Burgal, J., Shockey, J., and Browse, J. (2011) Castor phospholipid:diacylglycerol acyltransferase facilitates efficient metabolism of hydroxy fatty acids in transgenic Arabidopsis. Plant Physiol. 155, 683-693
    • (2011) Plant Physiol. , vol.155 , pp. 683-693
    • Van Erp, H.1    Bates, P.D.2    Burgal, J.3    Shockey, J.4    Browse, J.5
  • 8
    • 84859313687 scopus 로고    scopus 로고
    • The phosphatidylcholine diacylglycerol cholinephosphotransferase is required for efficient hydroxy fatty acid accumulation in transgenic Arabidopsis
    • Hu, Z., Ren, Z., and Lu, C. (2012) The phosphatidylcholine diacylglycerol cholinephosphotransferase is required for efficient hydroxy fatty acid accumulation in transgenic Arabidopsis. Plant Physiol. 158, 1944-1954
    • (2012) Plant Physiol. , vol.158 , pp. 1944-1954
    • Hu, Z.1    Ren, Z.2    Lu, C.3
  • 9
    • 0021764437 scopus 로고
    • Evidence for the reversibility of the acyl-CoA:lysophosphatidylcholine acyltransferase in microsomal preparations from developing safflower (Carthamus tinctorius L.) cotyledons and rat liver
    • Stymne, S., and Stobart, A. K. (1984) Evidence for the reversibility of the acyl-CoA:lysophosphatidylcholine acyltransferase in microsomal preparations from developing safflower (Carthamus tinctorius L.) cotyledons and rat liver. Biochem. J. 223, 305-314
    • (1984) Biochem. J. , vol.223 , pp. 305-314
    • Stymne, S.1    Stobart, A.K.2
  • 10
    • 0001126536 scopus 로고
    • Metabolism of glycerolipides: A comparison of lecithin and triglyceride synthesis
    • Lands, W. E. (1958) Metabolism of glycerolipides: a comparison of lecithin and triglyceride synthesis. J. Biol. Chem. 231, 883-888
    • (1958) J. Biol. Chem. , vol.231 , pp. 883-888
    • Lands, W.E.1
  • 11
    • 0001384244 scopus 로고
    • Metabolism of glycerolipids. 2. The enzymatic acylation of lysolecithin
    • Lands, W. E. (1960) Metabolism of glycerolipids. 2. The enzymatic acylation of lysolecithin. J. Biol. Chem. 235, 2233-2237
    • (1960) J. Biol. Chem. , vol.235 , pp. 2233-2237
    • Lands, W.E.1
  • 12
    • 84868322235 scopus 로고    scopus 로고
    • Acyl editing and headgroup exchange are the major mechanisms that direct polyunsaturated fatty acid flux into triacylglycerols
    • Bates, P. D., Fatihi, A., Snapp, A. R., Carlsson, A. S., Browse, J., and Lu, C. (2012) Acyl editing and headgroup exchange are the major mechanisms that direct polyunsaturated fatty acid flux into triacylglycerols. Plant Physiol. 160, 1530-1539
    • (2012) Plant Physiol. , vol.160 , pp. 1530-1539
    • Bates, P.D.1    Fatihi, A.2    Snapp, A.R.3    Carlsson, A.S.4    Browse, J.5    Lu, C.6
  • 15
    • 0025117420 scopus 로고
    • A simple enzymatic method for the preparation of radiolabeled erucoyl-CoA and other long-chain fatty acyl-CoAs and their characterization by mass spectrometry
    • Taylor, D. C., Weber, N., Hogge, L. R., and Underhill, E. W. (1990) A simple enzymatic method for the preparation of radiolabeled erucoyl-CoA and other long-chain fatty acyl-CoAs and their characterization by mass spectrometry. Anal. Biochem. 184, 311-316
    • (1990) Anal. Biochem. , vol.184 , pp. 311-316
    • Taylor, D.C.1    Weber, N.2    Hogge, L.R.3    Underhill, E.W.4
  • 18
    • 77954272855 scopus 로고    scopus 로고
    • TranslatorX: Multiple alignment of nucleotide sequences guided by amino acid translations
    • Abascal, F., Zardoya, R., and Telford, M. J. (2010) TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations. Nucleic Acids Res. 38, W7-W13
    • (2010) Nucleic Acids Res. , vol.38 , pp. W7-W13
    • Abascal, F.1    Zardoya, R.2    Telford, M.J.3
  • 19
    • 33747847779 scopus 로고    scopus 로고
    • PAL2NAL: Robust conversion of protein sequence alignments into the corresponding codon alignments
    • Suyama, M., Torrents, D., and Bork, P. (2006) PAL2NAL: Robust conversion of protein sequence alignments into the corresponding codon alignments. Nucleic Acids Res. 34, W609-W612
    • (2006) Nucleic Acids Res. , vol.34 , pp. W609-W612
    • Suyama, M.1    Torrents, D.2    Bork, P.3
  • 21
    • 79957471219 scopus 로고    scopus 로고
    • Enzymatic assembly of overlapping DNA fragments
    • Gibson, D. G. (2011) Enzymatic assembly of overlapping DNA fragments. Methods Enzymol. 498, 349-361
    • (2011) Methods Enzymol. , vol.498 , pp. 349-361
    • Gibson, D.G.1
  • 22
    • 0032873415 scopus 로고    scopus 로고
    • Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae
    • Goldstein, A. L., and McCusker, J. H. (1999) Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15, 1541-1553
    • (1999) Yeast , vol.15 , pp. 1541-1553
    • Goldstein, A.L.1    McCusker, J.H.2
  • 24
    • 36148984194 scopus 로고    scopus 로고
    • The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover
    • Chen, Q., Kazachkov, M., Zheng, Z., and Zou, J. (2007) The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover. FEBS Lett. 581, 5511-5516
    • (2007) FEBS Lett. , vol.581 , pp. 5511-5516
    • Chen, Q.1    Kazachkov, M.2    Zheng, Z.3    Zou, J.4
  • 26
    • 34347206860 scopus 로고    scopus 로고
    • High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
    • Gietz, R. D., and Schiestl, R. H. (2007) High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat. Protoc. 2, 31-34
    • (2007) Nat. Protoc. , vol.2 , pp. 31-34
    • Gietz, R.D.1    Schiestl, R.H.2
  • 27
    • 80052919515 scopus 로고    scopus 로고
    • Delete and repeat: A comprehensive toolkit for sequential gene knockout in the budding yeast Saccharomyces cerevisiae
    • Hegemann, J. H., and Heick, S. B. (2011) Delete and repeat: A comprehensive toolkit for sequential gene knockout in the budding yeast Saccharomyces cerevisiae. Methods Mol. Biol. 765, 189-206
    • (2011) Methods Mol. Biol. , vol.765 , pp. 189-206
    • Hegemann, J.H.1    Heick, S.B.2
  • 28
    • 0030138028 scopus 로고    scopus 로고
    • Functional expression of the extraplastidial Arabidopsis thaliana oleate desaturase gene (FAD2) in Saccharomyces cerevisiae
    • Covello, P. S., and Reed, D. W. (1996) Functional expression of the extraplastidial Arabidopsis thaliana oleate desaturase gene (FAD2) in Saccharomyces cerevisiae. Plant Physiol. 111, 223-226
    • (1996) Plant Physiol. , vol.111 , pp. 223-226
    • Covello, P.S.1    Reed, D.W.2
  • 29
    • 0034817021 scopus 로고    scopus 로고
    • Chillingsensitive, post-transcriptional regulation of a plant fatty acid desaturase expressed in yeast
    • Dyer, J. M., Chapital, D. C., Cary, J. W., and Pepperman, A. B. (2001) Chillingsensitive, post-transcriptional regulation of a plant fatty acid desaturase expressed in yeast. Biochem. Biophys. Res. Commun. 282, 1019-1025
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 1019-1025
    • Dyer, J.M.1    Chapital, D.C.2    Cary, J.W.3    Pepperman, A.B.4
  • 30
    • 33644838555 scopus 로고    scopus 로고
    • Oleate desaturase enzymes of soybean: Evidence of regulation through differential stability and phosphorylation
    • Tang, G. Q., Novitzky, W. P., Carol Griffin, H., Huber, S. C., and Dewey, R. E. (2005) Oleate desaturase enzymes of soybean: Evidence of regulation through differential stability and phosphorylation. Plant J. 44, 433-446
    • (2005) Plant J. , vol.44 , pp. 433-446
    • Tang, G.Q.1    Novitzky, W.P.2    Carol Griffin, H.3    Huber, S.C.4    Dewey, R.E.5
  • 31
    • 0032763186 scopus 로고    scopus 로고
    • Factors enhancing diacylglycerol acyltransferase activity in microsomes from cellsuspension cultures of oilseed rape
    • Byers, S. D., Laroche, A., Smith, K. C., and Weselake, R. J. (1999) Factors enhancing diacylglycerol acyltransferase activity in microsomes from cellsuspension cultures of oilseed rape. Lipids 34, 1143-1149
    • (1999) Lipids , vol.34 , pp. 1143-1149
    • Byers, S.D.1    Laroche, A.2    Smith, K.C.3    Weselake, R.J.4
  • 32
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E. G., and Dyer, W. J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 33
    • 70350247593 scopus 로고    scopus 로고
    • Simple methods to detect triacylglycerol biosynthesis in a yeast-based recombinant system
    • Siloto, R. M., Truksa, M., He, X., McKeon, T., and Weselake, R. J. (2009) Simple methods to detect triacylglycerol biosynthesis in a yeast-based recombinant system. Lipids 44, 963-973
    • (2009) Lipids , vol.44 , pp. 963-973
    • Siloto, R.M.1    Truksa, M.2    He, X.3    McKeon, T.4    Weselake, R.J.5
  • 35
    • 0002063329 scopus 로고
    • The enzymatic synthesis of triglycerides
    • Weiss, S. B., Kennedy, E. P., and Kiyasu, J. Y. (1960) The enzymatic synthesis of triglycerides. J. Biol. Chem. 235, 40-44
    • (1960) J. Biol. Chem. , vol.235 , pp. 40-44
    • Weiss, S.B.1    Kennedy, E.P.2    Kiyasu, J.Y.3
  • 36
    • 84934755666 scopus 로고    scopus 로고
    • Heterologous expression of flax phosphotidylcholine: Diacylglycerol cholinephosphotransferases (PDCTs) increases polyunsaturated fatty acid content in yeast and Arabidopsis seeds
    • in press
    • Wickramarathna, A. D., Siloto, R. M. P., Mietkiewska, E., Singer, S. D., Pan, X., and Weselake, R. J. (2015) Heterologous expression of flax phosphotidylcholine: diacylglycerol cholinephosphotransferases (PDCTs) increases polyunsaturated fatty acid content in yeast and Arabidopsis seeds. BMC Biotechnol., in press
    • (2015) BMC Biotechnol.
    • Wickramarathna, A.D.1    Siloto, R.M.P.2    Mietkiewska, E.3    Singer, S.D.4    Pan, X.5    Weselake, R.J.6
  • 37
    • 84871876502 scopus 로고    scopus 로고
    • Metabolic interactions between the Lands cycle and the Kennedy pathway of glycerolipid synthesis in Arabidopsis developing seeds
    • Wang, L., Shen, W., Kazachkov, M., Chen, G., Chen, Q., Carlsson, A. S., Stymne, S., Weselake, R. J., and Zou, J. (2012) Metabolic interactions between the Lands cycle and the Kennedy pathway of glycerolipid synthesis in Arabidopsis developing seeds. Plant Cell 24, 4652-4669
    • (2012) Plant Cell , vol.24 , pp. 4652-4669
    • Wang, L.1    Shen, W.2    Kazachkov, M.3    Chen, G.4    Chen, Q.5    Carlsson, A.S.6    Stymne, S.7    Weselake, R.J.8    Zou, J.9
  • 38
    • 50849094188 scopus 로고    scopus 로고
    • Metabolic engineering of hydroxy fatty acid production in plants: RcDGAT2 drives dramatic increases in ricinoleate levels in seed oil
    • Burgal, J., Shockey, J., Lu, C., Dyer, J., Larson, T., Graham, I., and Browse, J. (2008) Metabolic engineering of hydroxy fatty acid production in plants: RcDGAT2 drives dramatic increases in ricinoleate levels in seed oil. Plant Biotechnol. J. 6, 819-831
    • (2008) Plant Biotechnol. J. , vol.6 , pp. 819-831
    • Burgal, J.1    Shockey, J.2    Lu, C.3    Dyer, J.4    Larson, T.5    Graham, I.6    Browse, J.7


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