NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms

FASEB Journal

Volumn 29, Issue 4, 2015, Pages 1269-1279

  Qu, Chao ^a   Bonar, Sheri L ^a   Hickman Brecks, Cynthia L ^a   Abu Amer, Samer ^a   McGeough, Matthew D ^b   Peña, Carla A ^b   Broderick, Lori ^b   Yang, Chang ^a   Grimston, Susan K ^a   Kading, Jacqueline ^a   Abu Amer, Yousef ^a   Novack, Deborah V ^a   Hoffman, Hal M ^b   Civitelli, Roberto ^a   Mbalaviele, Gabriel ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cryopyrinopathies; IL 1 ; NOMID; Osteoclasts; PARP1

Indexed keywords

COLONY STIMULATING FACTOR 1; CRYOPYRIN; F ACTIN; INTERLEUKIN 1BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OSTEOCLAST DIFFERENTIATION FACTOR; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; INFLAMMASOME; MUTANT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE;

ACTIN FILAMENT; ALLELE; ANIMAL EXPERIMENT; ARTICLE; BODY HEIGHT; BONE MARROW CELL; BONE MASS; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; UPREGULATION; ANIMAL; BONE DISEASES, METABOLIC; C57BL MOUSE; CELL LINEAGE; CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES; DISEASE MODEL; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MUTANT MOUSE STRAIN; OSTEOCLAST; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

MUS;

ANIMALS; BONE DISEASES, METABOLIC; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL LINEAGE; CRYOPYRIN-ASSOCIATED PERIODIC SYNDROMES; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMASOMES; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUTANT PROTEINS; MYELOID CELLS; OSTEOCLASTS; OSTEOLYSIS; POLY(ADP-RIBOSE) POLYMERASES; PROTEOLYSIS;

EID: 84937427135     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-264804     Document Type: Article

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