-
1
-
-
84888132076
-
US-National institutes of Healthfunded research for cutaneous wounds in 2012
-
Richmond NA, Lamel SA, Davidson JM, et al. US-National institutes of Healthfunded research for cutaneous wounds in 2012. Wound Repair Reg 2013;21:789-92
-
(2013)
Wound Repair Reg
, vol.21
, pp. 789-792
-
-
Richmond, N.A.1
Lamel, S.A.2
Davidson, J.M.3
-
2
-
-
84934968330
-
Preclinical and clinical evidence for stem cell therapies as treatment for diabetic wounds
-
[Epub ahead of print]
-
Heublein H, Bader A, Giri S. Preclinical and clinical evidence for stem cell therapies as treatment for diabetic wounds. Drug Discov Today 2015. [Epub ahead of print]
-
(2015)
Drug Discov Today
-
-
Heublein, H.1
Bader, A.2
Giri, S.3
-
3
-
-
84911879917
-
Advances in skin grafting and treatment of cutaneous wounds
-
Sun BK, Siprashvilli Z, Khavari PA. Advances in skin grafting and treatment of cutaneous wounds. Science 2014;346:941-5
-
(2014)
Science
, vol.346
, pp. 941-945
-
-
Sun, B.K.1
Siprashvilli, Z.2
Khavari, P.A.3
-
4
-
-
27744448125
-
Wound healing and its impairment in the diabetic foot
-
Falanga V. Wound healing and its impairment in the diabetic foot. Lancet 2005;366:1736-43
-
(2005)
Lancet
, vol.366
, pp. 1736-1743
-
-
Falanga, V.1
-
7
-
-
84886601180
-
Steroidogenesis in the skin: Implication for local immune functions
-
Slominski A, Zbytek B, Nikolakis G, et al. Steroidogenesis in the skin: implication for local immune functions. J Steroid Biochem Mol Biol 2013;137:107-23
-
(2013)
J Steroid Biochem Mol Biol
, vol.137
, pp. 107-123
-
-
Slominski, A.1
Zbytek, B.2
Nikolakis, G.3
-
8
-
-
84901490008
-
Cutaneous glucocorticosteroidogenesis: Securing local homeostasis and the skin integrity
-
Slominski AT, Manna PR, Tuckey RC. Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity. Exp Dermatol 2014;23:369-74
-
(2014)
Exp Dermatol
, vol.23
, pp. 369-374
-
-
Slominski, A.T.1
Manna, P.R.2
Tuckey, R.C.3
-
9
-
-
79953184635
-
Cortisol synthesis in epidermis is induced by IL-1 and tissue injury
-
Vukelic S, Stojadinovic O, Pastar I, et al. Cortisol synthesis in epidermis is induced by IL-1 and tissue injury. J Biol Chem 2011;286:10265-75
-
(2011)
J Biol Chem
, vol.286
, pp. 10265-10275
-
-
Vukelic, S.1
Stojadinovic, O.2
Pastar, I.3
-
11
-
-
84925341588
-
Chronic wound repair and healing in older adults: Current status and future research
-
Gould L, Abadir P, Brem H, et al. Chronic wound repair and healing in older adults: current status and future research. Wound Rep Regen 2015;63(3):427-38
-
(2015)
Wound Rep Regen
, vol.63
, Issue.3
, pp. 427-438
-
-
Gould, L.1
Abadir, P.2
Brem, H.3
-
12
-
-
84908895813
-
Epithelialization in wound healing: A comprehensive review
-
Pastar I, Stojadinovic O, Yin NC, et al. Epithelialization in wound healing: A comprehensive review. Adv Wound Care 2014;3:445-64
-
(2014)
Adv Wound Care
, vol.3
, pp. 445-464
-
-
Pastar, I.1
Stojadinovic, O.2
Yin, N.C.3
-
13
-
-
13544259736
-
Cellular and molecular facets of keratinocyte reepithelization during wound healing
-
Santoro MM, Gaudino G. Cellular and molecular facets of keratinocyte reepithelization during wound healing. Exp Cell Res 2005;304:274-86
-
(2005)
Exp Cell Res
, vol.304
, pp. 274-286
-
-
Santoro, M.M.1
Gaudino, G.2
-
14
-
-
84858126311
-
The role of endogenous enzymes in chronic wounds: A focus on the implications of aberrant levels of both host and bacterial proteases in wound healing
-
Carty SM, Cochrane CA, Clegg PD, Percival SL. The role of endogenous enzymes in chronic wounds: A focus on the implications of aberrant levels of both host and bacterial proteases in wound healing. Wound Rep Reg 2012;20:125-36
-
(2012)
Wound Rep Reg
, vol.20
, pp. 125-136
-
-
Carty, S.M.1
Cochrane, C.A.2
Clegg, P.D.3
Percival, S.L.4
-
15
-
-
84878529977
-
Gap junction remodeling in skin repair following wounding and disease
-
Churko JM, Laird DW. Gap junction remodeling in skin repair following wounding and disease. Physiology 2013;28:190-8
-
(2013)
Physiology
, vol.28
, pp. 190-198
-
-
Churko, J.M.1
Laird, D.W.2
-
18
-
-
84860716906
-
Dexamethasone inhibits TGF-2-induced migration of human lens epithelial cells: Implications for posterior capsule opacification prevention
-
Yao J, Yang W, Liu Y, et al. Dexamethasone inhibits TGF-2-induced migration of human lens epithelial cells: implications for posterior capsule opacification prevention. Mol Med Reports 2012;5:1509-13
-
(2012)
Mol Med Reports
, vol.5
, pp. 1509-1513
-
-
Yao, J.1
Yang, W.2
Liu, Y.3
-
19
-
-
84867021930
-
Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis
-
Shikatani EA, Trifonova A, Mandel ER, et al. Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis. PLoS ONE 2012;7:e46625
-
(2012)
PLoS ONE
, vol.7
, pp. e46625
-
-
Shikatani, E.A.1
Trifonova, A.2
Mandel, E.R.3
-
20
-
-
84879638689
-
11b-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects
-
Tiganescu A, Tahrani AA, Morgan SA, et al. 11b-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects. J Clin Invest 2013;123:3051-60
-
(2013)
J Clin Invest
, vol.123
, pp. 3051-3060
-
-
Tiganescu, A.1
Tahrani, A.A.2
Morgan, S.A.3
-
21
-
-
84882824040
-
Corticosteroids and wound healing: Clinical considerations in the perioperative period
-
Wang AS, Armstrong EJ, Armstrong AW. Corticosteroids and wound healing: clinical considerations in the perioperative period. Am J Surg 2013;206:410-17
-
(2013)
Am J Surg
, vol.206
, pp. 410-417
-
-
Wang, A.S.1
Armstrong, E.J.2
Armstrong, A.W.3
-
22
-
-
80051710067
-
Optimization of the first selective steroid-11b-hydroxylase (CYP11B1) inhibitors for the treatment of cortisol dependent diseases
-
Hille UE, Zimmer C, Haupenthal J, Hartmann RW. Optimization of the first selective steroid-11b-hydroxylase (CYP11B1) inhibitors for the treatment of cortisol dependent diseases. ACS Med Chem. Lett 2011;2:559-64
-
(2011)
ACS Med Chem. Lett
, vol.2
, pp. 559-564
-
-
Hille, U.E.1
Zimmer, C.2
Haupenthal, J.3
Hartmann, R.W.4
-
23
-
-
84880174933
-
Cushing's syndrome: Development of highly potent and selective CYP11B1 inhibitors of the (pyridylmethyl)-pyridine type
-
Emmerich J, Hu Q, Hanke N, Hartmann RW. Cushing's syndrome: development of highly potent and selective CYP11B1 inhibitors of the (pyridylmethyl)-pyridine type. J Med Chem 2013;56:6022-32
-
(2013)
J Med Chem
, vol.56
, pp. 6022-6032
-
-
Emmerich, J.1
Hu, Q.2
Hanke, N.3
Hartmann, R.W.4
-
24
-
-
84907462346
-
Potent 11-hydroxylase inhibitors with inverse metabolic stability in human plasma and hepatic S9 fractions to promote wound healing
-
Zhu W, Hu Q, Hanke N, et al. Potent 11-hydroxylase inhibitors with inverse metabolic stability in human plasma and hepatic S9 fractions to promote wound healing. J Med Chem 2014;57:7811-17
-
(2014)
J Med Chem
, vol.57
, pp. 7811-7817
-
-
Zhu, W.1
Hu, Q.2
Hanke, N.3
-
25
-
-
84962058168
-
Selective Cyp11b1 inhibitors for the treatment of cortisol dependent diseases
-
Hartmann R, Hille U, Hu Q, et al. Selective Cyp11b1 inhibitors for the treatment of cortisol dependent diseases. WO2012052540 A1; 2012
-
WO2012052540 A1
, vol.2012
-
-
Hartmann, R.1
Hille, U.2
Hu, Q.3
-
26
-
-
84937236193
-
11b-Hydroxysteroid dehydrogenases
-
Bionetworks GmbH
-
Bionetworks GmbH. Wilckens T. 11b-Hydroxysteroid dehydrogenases. WO 2006097337 A2; 2006
-
(2006)
WO 2006097337 A2
-
-
Wilckens, T.1
-
27
-
-
84937236194
-
Substituted azole aromatic heterocycles as inhibitors of 11b-HSD-1
-
Amgen Inc.
-
Amgen Inc. Biovitrum Ab. Substituted azole aromatic heterocycles as inhibitors of 11b-HSD-1. WO2008011453 A2; 2008
-
(2008)
WO2008011453 A2
-
-
Biovitrum, A.B.1
-
28
-
-
84937236195
-
Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1
-
Amgen Inc.
-
Amgen Inc. Biovitrum. Ab. Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1. CA2630718 A1; 2007
-
(2007)
CA2630718 A1
-
-
Biovitrum, A.B.1
-
29
-
-
84937236196
-
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
-
Vitae Pharmaceuticals Inc.
-
Vitae Pharmaceuticals Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1. WO2010091067 A2; 2010
-
(2010)
WO2010091067 A2
-
-
-
30
-
-
43749094102
-
First-class delivery:Getting growth factors to their destination
-
Davidson JM. First-class delivery: getting growth factors to their destination. J Invest Dermatol 2008;128:1360-2
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1360-1362
-
-
Davidson, J.M.1
-
31
-
-
77953958239
-
Application of a PDGF-containing novel gel for ctaneous wound healing
-
Judith R, Nithya M, Rose C, et al. Application of a PDGF-containing novel gel for ctaneous wound healing. Life Sci 2010;87:1-8
-
(2010)
Life Sci
, vol.87
, pp. 1-8
-
-
Judith, R.1
Nithya, M.2
Rose, C.3
-
32
-
-
33846903306
-
Recombinant human platelet-derived growth factor enhanced dermal wound healing by a pathway involving ERK and c-fos in diabetic rats
-
Cheng B, Liu HW, Fu XB, et al. Recombinant human platelet-derived growth factor enhanced dermal wound healing by a pathway involving ERK and c-fos in diabetic rats. J Dermatol Sci 2007;45:193-201
-
(2007)
J Dermatol Sci
, vol.45
, pp. 193-201
-
-
Cheng, B.1
Liu, H.W.2
Fu, X.B.3
-
33
-
-
38849118281
-
Collagen membranes loaded with collagen-binding human PDGF-BB accelerate wound healing in a rabbit dermal ischemic ulcer model
-
Sun W, Lin H, Xie H, et al. Collagen membranes loaded with collagen-binding human PDGF-BB accelerate wound healing in a rabbit dermal ischemic ulcer model. Growth Fact 2007;25:309-18
-
(2007)
Growth Fact
, vol.25
, pp. 309-318
-
-
Sun, W.1
Lin, H.2
Xie, H.3
-
34
-
-
84937236197
-
Methods of stimulating wound healing by administration of vascular endothelial growth factor D (VEGF-D)
-
Vegenics Pty Ltd
-
Vegenics Pty Ltd. Methods of stimulating wound healing by administration of vascular endothelial growth factor D (VEGF-D). US8227410 B2; 2012
-
US8227410 B2
, vol.2012
-
-
-
35
-
-
84937236198
-
Novel peptides for wound healing
-
Gene Signal International SA.
-
Gene Signal International SA. Novel peptides for wound healing. US20110306545 A1; 2011
-
(2011)
US20110306545 A1
-
-
-
36
-
-
84937236199
-
Matrix metalloproteinase inhibitors
-
Ranbaxy Laboratories Ltd.
-
Ranbaxy Laboratories Ltd. Matrix metalloproteinase inhibitors. US8846910 B2; 2014
-
(2014)
US8846910 B2
-
-
-
37
-
-
84962081718
-
Thiazol derivatives as pro-matrix metalloproteinase inhibitors
-
Janssen Pharmaceutica NV. Thiazol derivatives as pro-matrix metalloproteinase inhibitors. WO2012162468 A1; 2012
-
(2012)
WO2012162468 A1
-
-
Janssen Pharmaceutica, N.V.1
-
38
-
-
84937236201
-
Metalloproteinase 9 and metalloproteinase 2 binding proteins
-
Dyax Corp
-
Dyax Corp. Metalloproteinase 9 and metalloproteinase 2 binding proteins. US8013125 B2. 2011
-
(2011)
US8013125 B2.
-
-
-
39
-
-
84937236202
-
Polypeptides that bind tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
-
Amgen
-
Amgen. Polypeptides that bind tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods. US20140228540 A1; 2014
-
(2014)
US20140228540 A1
-
-
-
40
-
-
84937236203
-
Metalloproteinase inhibitors for wound healing
-
Kimberly-Clark Worldwide, Inc
-
Kimberly-Clark Worldwide, Inc. Metalloproteinase inhibitors for wound healing. US7186693 B2; 2007
-
(2007)
US7186693 B2
-
-
-
41
-
-
84904749172
-
The role of hypoxia-inducible factor in wound healing
-
Hong WX, Hu MS, Esquivel M, et al. The role of hypoxia-inducible factor in wound healing. Adv Wound Care 2014;3:390-9
-
(2014)
Adv Wound Care
, vol.3
, pp. 390-399
-
-
Hong, W.X.1
Hu, M.S.2
Esquivel, M.3
-
42
-
-
84937236204
-
Substituted dihydropyrazolones and use thereof as HIF-prolyl-4-hydroxylase inhibitors
-
Bayer Intellectual Property GmbH
-
Bayer Intellectual Property GmbH. Substituted dihydropyrazolones and use thereof as HIF-prolyl-4-hydroxylase inhibitors. US8524699 B2; 2013
-
US8524699 B2
, vol.2013
-
-
-
43
-
-
84937236205
-
Diazaquinolones that inhibit prolyl hydroxylase activity
-
Amgen.
-
Amgen. Diazaquinolones that inhibit prolyl hydroxylase activity. US8097620 B2; 2012
-
(2012)
US8097620 B2
-
-
-
44
-
-
84937236206
-
Prolyl hydroxylase inhibitors
-
GlaxoSmithKline Llc.
-
GlaxoSmithKline Llc. Prolyl hydroxylase inhibitors. WO2010059552 A1; 2010
-
(2010)
WO2010059552 A1
-
-
-
45
-
-
84962120777
-
Benzoimidazole glycinamides as prolyl hydroxylase inhibitors
-
Janssen Pharmaceutica N. V. Benzoimidazole glycinamides as prolyl hydroxylase inhibitors. WO2009134754 A1; 2009
-
(2009)
WO2009134754 A1
-
-
Janssen Pharmaceutica, N.V.1
-
46
-
-
84919457239
-
Regulation of wound healing and fibrosis by hypoxia and hypoxia-inducible factor-1
-
Ruthenborg RJ, Ban J-J, Wazir A, et al. Regulation of wound healing and fibrosis by hypoxia and hypoxia-inducible factor-1. Mol Cells 2014;37:637-43
-
(2014)
Mol Cells
, vol.37
, pp. 637-643
-
-
Ruthenborg, R.J.1
Ban, J.-J.2
Wazir, A.3
-
47
-
-
84875756145
-
Concise review: Role of mesenchymal stem cells in wound repair
-
Maxson S, Lopez EA, Yoo D, et al. Concise review: role of mesenchymal stem cells in wound repair. Stem Cells Trans Med 2012;1:142-9
-
(2012)
Stem Cells Trans Med
, vol.1
, pp. 142-149
-
-
Maxson, S.1
Lopez, E.A.2
Yoo, D.3
-
48
-
-
84872783947
-
Therapeutic potential of bone marrowderived mesenchymal stem cells for cutaneous wound healing
-
Chen JS, Wong VW, Gurtner GC. Therapeutic potential of bone marrowderived mesenchymal stem cells for cutaneous wound healing. Front Immun 2012;3:192
-
(2012)
Front Immun
, vol.3
, pp. 192
-
-
Chen, J.S.1
Wong, V.W.2
Gurtner, G.C.3
-
49
-
-
84901438924
-
Activity of mesenchymal stem cells in therapies for chronic skin wound healing
-
Nuschke A. Activity of mesenchymal stem cells in therapies for chronic skin wound healing. Organesis 2014;10:29-37
-
(2014)
Organesis
, vol.10
, pp. 29-37
-
-
Nuschke, A.1
-
50
-
-
84937236208
-
Cell therapy to improve wound healing and related compositions and methods
-
Cryo-Cell International, Inc
-
Cryo-Cell International, Inc. Cell therapy to improve wound healing and related compositions and methods. EP2553089 A1; 2013
-
EP2553089 A1
, vol.2013
-
-
-
51
-
-
84937236209
-
Mesenchymal stem cells and uses therefor
-
Mesoblast International Sarl.
-
Mesoblast International Sarl. Mesenchymal stem cells and uses therefor. US 2011/0318314 A1; 2011
-
(2011)
US 2011/0318314 A1
-
-
-
52
-
-
84937236210
-
Stem cell, precursor cell, or target cellbased treatment of multi-organ failure and renal dysfunction
-
US Department of Veterans Affairs, University of Utah Research Foundation
-
US Department of Veterans Affairs, University of Utah Research Foundation. Stem cell, precursor cell, or target cellbased treatment of multi-organ failure and renal dysfunction. US20140086886 A1; 2014
-
(2014)
US20140086886 A1
-
-
-
53
-
-
84937236211
-
Methods of culturing and expanding mesenchymal stem cells and isolated cell populations generated thereby
-
Gamida Cell Ltd.
-
Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells and isolated cell populations generated thereby. US20140023623 A1; 2014
-
(2014)
US20140023623 A1
-
-
-
54
-
-
84855432805
-
Characterization of potential elastase inhibitor-peptides regulated by a molecular switch for wound dressings applications
-
Barros SC, Martins JA, Marcos JC, Cavaco-Paulo A. Characterization of potential elastase inhibitor-peptides regulated by a molecular switch for wound dressings applications. Enzym Micro Tec 2012;50:107-14
-
(2012)
Enzym Micro Tec
, vol.50
, pp. 107-114
-
-
Barros, S.C.1
Martins, J.A.2
Marcos, J.C.3
Cavaco-Paulo, A.4
-
55
-
-
84919784244
-
Proteases and delayed wound healing
-
Carty SM, Percival SL. Proteases and delayed wound healing. Adv Wound Care 2013;2:438-47
-
(2013)
Adv Wound Care
, vol.2
, pp. 438-447
-
-
Carty, S.M.1
Percival, S.L.2
-
56
-
-
84962127132
-
Methods to accelerate tissue and wound healing rates and reduce swelling and scar formation
-
Delano FA, Schonbein GW. Methods to accelerate tissue and wound healing rates and reduce swelling and scar formation. WO2011038417 A2; 2011
-
WO2011038417 A2
, vol.2011
-
-
Delano, F.A.1
Schonbein, G.W.2
-
59
-
-
84866005644
-
Regulation of connexin43 gap junction protein triggers vascular recovery and healing in human ocular persistent epithelial defect wounds
-
Ormondo S, Chou C-Y, Goold L, et al. Regulation of connexin43 gap junction protein triggers vascular recovery and healing in human ocular persistent epithelial defect wounds. J Membr Biol 2012;245:381-8
-
(2012)
J Membr Biol
, vol.245
, pp. 381-388
-
-
Ormondo, S.1
Chou, C.-Y.2
Goold, L.3
-
60
-
-
84885649941
-
A connexin43 mimetic peptide promotes regenerative healing and improves mechanical properties in skin and heart
-
Ongstad EL, O'Quinn MP, Ghatnekar G. A connexin43 mimetic peptide promotes regenerative healing and improves mechanical properties in skin and heart. Adv Wound Care 2013;2:55-62
-
(2013)
Adv Wound Care
, vol.2
, pp. 55-62
-
-
Ongstad, E.L.1
O'quinn, M.P.2
Ghatnekar, G.3
-
61
-
-
84925956562
-
The effect of a connexin43. Based peptide on the healing of chronic venous leg ulcers: A multicenter, randomized trial
-
The first clinical data on Cx43 inhibitor to promote wound healing in chronic venous ulcer.
-
Ghatnekar GS, Grek CL, Armstrong DG, et al. The effect of a connexin43. based peptide on the healing of chronic venous leg ulcers: A multicenter, randomized trial. J Invest Dermatol 2015;135:289-98. The first clinical data on Cx43 inhibitor to promote wound healing in chronic venous ulcer.
-
(2015)
J Invest Dermatol
, vol.135
, pp. 289-298
-
-
Ghatnekar, G.S.1
Grek, C.L.2
Armstrong, D.G.3
-
62
-
-
84962118131
-
Compositions and methods for promoting wound healing and tissue regeneration
-
Gourdie R, Ghatnekar G, Jourdan J. Compositions and methods for promoting wound healing and tissue regeneration. EP2377546 A2; 2011
-
(2011)
EP2377546 A2
-
-
Gourdie, R.1
Ghatnekar, G.2
Jourdan, J.3
-
63
-
-
84937236216
-
Anti-connexin compounds targeted to connexins and methods of use thereof
-
Coda Therapeutics Inc.
-
Coda Therapeutics Inc. Anti-connexin compounds targeted to connexins and methods of use thereof. US8815819; 2014
-
(2014)
US8815819
-
-
|