Synthesis and evaluation of 4-[18F]fluoropropoxy-3-iodobenzylguanidine ([18F]FPOIBG): A novel 18F-labeled analogue of MIBG

Nuclear Medicine and Biology

Volumn 42, Issue 8, 2015, Pages 673-684

  Vaidyanathan, Ganesan ^a   McDougald, Darryl ^a   Koumarianou, Eftychia ^a   Choi, Jaeyeon ^a   Hens, Marc ^a   Zalutsky, Michael R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Fluorine 18; MIBG; Neuroendocrine tumors; Norepinephrine transporter; PET imaging

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 125; (3 IODOBENZYL)GUANIDINE I 131; 4 (3 FLUOROPROPOXY) 3 BROMOBENZYLGUANIDINE F 18; 4 FLUOROPROPOXY 3 IODOBENZYLGUANIDINE F 18; DIAGNOSTIC AGENT; IODINE 4 FLUOROPROPOXY 3 IODOBENZYLGUANIDINE I 125; NORADRENALIN TRANSPORTER; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; (3 IODOBENZYL)GUANIDINE; FLUORINE; GUANIDINE DERIVATIVE; IODOBENZENE; SLC6A2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ANIMAL; AUTORADIOGRAPHY; BAGG ALBINO MOUSE; CHEMISTRY; DIAGNOSTIC IMAGING; DRUG SCREENING; EVALUATION STUDY; GLIOMA; ISOTOPE LABELING; METABOLIC CLEARANCE RATE; METABOLISM; NEUROBLASTOMA; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; SYNTHESIS; TISSUE DISTRIBUTION; TUMOR CELL CULTURE;

3-IODOBENZYLGUANIDINE; ANIMALS; AUTORADIOGRAPHY; FLUORINE RADIOISOTOPES; GLIOMA; GUANIDINES; IODOBENZENES; ISOTOPE LABELING; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED BALB C; NEUROBLASTOMA; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84937191407     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2015.04.005     Document Type: Article

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