Neuroprotective Effect of Gui Zhi (Ramulus Cinnamomi) on Ma Huang- (Herb Ephedra-) Induced Toxicity in Rats Treated with a Ma Huang-Gui Zhi Herb Pair

Evidence-based Complementary and Alternative Medicine

Volumn 2015, Issue , 2015, Pages

  Zheng, Fang Hao ^a   Wei, Ping ^a   Huo, Hui Ling ^a   Xing, Xue Feng ^a   Chen, Fei Long ^a   Tan, Xiao Mei ^a   Luo, Jia Bo ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHINESE DRUG; EPHEDRA SINICA EXTRACT; EPHEDRINE; GUI ZHI; NEUROPROTECTIVE AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRANCHLET; CINNAMON; CONTROLLED STUDY; DRUG SYNTHESIS; EPHEDRA SINICA; LOCOMOTION; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT;

EID: 84937157843     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2015/913461     Document Type: Article

References (59)

1. B. G. Zhang and Q. F. Liu, "The pharmacological research and clinical application of Guizhi-Mahuang Geban-Tang, " Chinese Traditional Patent Medicine, vol. 34, no. 3, pp. 539-541, 2012.
2. H. Wang and L. Zhu, "The research on the clinical application of Mahung Tang and related prescription, " Asia-Pacific Traditional Medicine, vol. 7, no. 4, pp. 40-42, 2011.
3. Y. S. Shan and X. Z. Sun, "Acase of Ephedra poinsoning induced by overdose comsumption, " Heilongjiang Journal of Traditional Chinese Medicine, vol. 7, no. 5, pp. 41-42, 2001.
4. Y. H. Fu, "Death caused by Ephedra poisoning: a case report, " Chinese Journal of Forensic Medicine, vol. 12, no. 4, p. 252, 1997.
5. L. Wang and Y. Liu, "A case of arryhthmia aggravated by overdose of raw Ephedra, "Henan Tradtitional ChineseMedicine, vol. 15, no. 2, p. 111, 1995.
6. C. M. Flanagan, J. L. Kaesberg, E. S. Mitchell, M. A. Ferguson, and M. C. P. Haigney, "Coronary artery aneurysm and thrombosis following chronic ephedra use, " International Journal of Cardiology, vol. 139, no. 1, pp. e11-e13, 2010.
7. C. M. Peters, J. O. O'Neill, J. B. Young, andC. Bott-Silverman, "Is there an association between ephedra and heart failure a case series, " Journal of Cardiac Failure, vol. 11, no. 1, pp. 9-11, 2005.
8. C. Chen, J. Biller, S. J. Willing, and A. M. Lopez, "Ischemic stroke after using over the counter products containing ephedra, " Journal of the Neurological Sciences, vol. 217, no. 1, pp. 55-60, 2004.
9. E. Martnez-Quintana, F. Rodrguez-González, and J. Cuba-Herrera, "Myocardial necrosis and severe biventricular dysfunction in the context of chronic ephedrine abuse, " Adicciones, vol. 22, no. 1, pp. 25-28, 2010.
10. F. Varlibas, I. Delipoyraz, G. Yuksel, G. Filiz, H. Tireli, and N. O. Gecim, "Neurotoxicity following chronic intravenous use of 'Russian cocktail', " Clinical Toxicology, vol. 47, no. 2, pp. 157-160, 2009.
11. F. J. Moawad, J. D. Hartzell, T. J. Biega, and C. J. Lettieri, "Transient blindness due to posterior reversible encephalopathy syndrome following ephedra overdose, " Southern Medical Journal, vol. 99, no. 5, pp. 511-514, 2006.
12. R. B. Rothman, M. H. Baumann, C. M. Dersch et al., "Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin, " Synapse, vol. 39, no. 1, pp. 32-41, 2001.
13. W. S. CarlosPostonII, J. P. Foreyt, L. Borrell, andC. K. Haddock, "Challenges in obesity management, " SouthernMedical Journal, vol. 91, no. 8, pp. 710-720, 1998.
14. C. F. Herridge and M. F. a'Brook, "Ephedrine psychosis, " British Medical Journal, vol. 2, no. 598, p. 160, 1968.
15. A. M. Whitehouse and J. M. Duncan, "Ephedrine psychosis rediscovered, " British Journal of Psychiatry, vol. 150, pp. 258-261, 1987.
16. T. C. Theoharides, "Sudden death of a healthy college student related to ephedrine toxicity from a ma huang-containing drink, " Journal of Clinical Psychopharmacology, vol. 17, no. 5, pp. 437-439, 1997.
17. X. M. Zhang, Studies on Conserving Effect and Reducing Toxicity Integrated Mechanism of the Effect/Toxicity Amphiprotic Components from Ma-Xing-Shi-Gan Prescription-Central Nervous System, SouthernMedical University, GuangZhou, China, 2012.
18. A. M. Reddy, J. H. Seo, S. Y. Ryu, Y. S. Kim, and K. R. Min, "Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-B inhibitors from Cinnamomum cassia, " Planta Medica, vol. 70, no. 9, pp. 823-827, 2004.
19. L. K. Chao, K.-F. Hua, H.-Y. Hsu et al., "Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/ macrophages through suppression of intracellular signaling, " Food and Chemical Toxicology, vol. 46, no. 1, pp. 220-231, 2008.
20. J. Y. Guo, H. R. Huo, B. S. Zhao et al., "Cinnamaldehyde reduces IL-1beta-induced cyclooxygenase-2 activity in rat cerebral microvascular endothelial cells, " European Journal of Pharmacology, vol. 537, no. 1-3, pp. 174-180, 2006.
21. H.-S. Lee, B.-S. Kim, and M.-K. Kim, "Suppression effect of Cinnamomum cassia bark-derived component on nitric oxide synthase, " Journal of Agricultural and Food Chemistry, vol. 50, no. 26, pp. 7700-7703, 2002.
22. D. H. Kim, C. H. Kim, M.-S. Kim et al., "Suppression of agerelated inflammatory NF-kappaB activation by cinnamaldehyde, " Biogerontology, vol. 8, no. 5, pp. 545-554, 2007.
23. S.-C. Ho, K.-S. Chang, and P.-W. Chang, "Inhibition of neuroinflammation by cinnamon and its main components, " Food Chemistry, vol. 138, no. 4, pp. 2275-2282, 2013.
24. R. C. George, J. Lew, and D. J. Graves, "Interaction of cinnamaldehyde and epicatechin with tau: implications of beneficial effects in modulating alzheimer's disease pathogenesis, " Journal of Alzheimer's Disease, vol. 36, no. 1, pp. 21-40, 2013.
25. D. K. Miller, L. R. McMahon, T. A. Green, J. R. Nation, and P. J. Wellman, "Repeated administration of ephedrine induces behavioral sensitization in rats, " Psychopharmacology, vol. 140, no. 1, pp. 52-56, 1998.
26. D. H. Zeef, R. Vlamings, L. W. Limet al., "Motor andnon-motor behaviour in experimental Huntington's disease, " Behavioural Brain Research, vol. 226, no. 2, pp. 435-439, 2012.
27. S. Wang, Y. Hu, W. Tan et al., "Compatibility art of traditional Chinese medicine: from the perspective of herb pairs, " Journal of Ethnopharmacology, vol. 143, no. 2, pp. 412-423, 2012.
28. L. Wang, J. Zhang, Y. Hong, Y. Feng, M. Chen, and Y. Wang, "Phytochemical and pharmacological review of da Chuanxiong formula: a famous herb pair composed of chuanxiong rhizoma and gastrodiae rhizoma for headache, " Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 425369, 16 pages, 2013.
29. K. C. Montgomery, "Therelation between fear induced by novel stimulation and exploratory behavior, " Journal of Comparative and Physiological Psychology, vol. 48, no. 4, pp. 254-260, 1955.
30. L. Prut and C. Belzung, "The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review, " European Journal of Pharmacology, vol. 463, no. 1-3, pp. 3-33, 2003.
31. P. J. Wellman, D. K. Miller, C. L. Livermore, T. A. Green, L. R. McMahon, and J. R. Nation, "Effects of (-)-ephedrine on locomotion, feeding, and nucleus accumbens dopamine in rats, " Psychopharmacology, vol. 135, no. 2, pp. 133-140, 1998.
32. H. Watanabe, M. Hagiwara, M. Tohda, Y. Hiyama, K. Terasawa, and K. Watanabe, "Central effects of cinnamaldehyde, " Yakugaku Zasshi, no. 10, pp. 1095-1100, 1984.
33. M. T. Bardo, "Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens, " Critical Reviews in Neurobiology, vol. 12, no. 1-2, pp. 37-67, 1998.
34. Y. Arieli, M. Eynan, H. Gancz, R. Arieli, and Y. Kashi, "Heat acclimation prolongs the time to central nervous systemoxygen toxicity in the rat: possible involvement of HSP72, " Brain Research, vol. 962, no. 1-2, pp. 15-20, 2003.
35. I. T. Demchenko, D. N. Atochin, A. E. Boso, J. Astern, P. L. Huang, and C. A. Piantadosi, "Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases, " Neuroscience Letters, vol. 344, no. 1, pp. 53-56, 2003.
36. D. Torbati, D. F. Church, J. M. Keller, and W. A. Pryor, "Free radical generation in the brain precedes hyperbaric oxygeninduced convulsions, " Free Radical Biology and Medicine, vol. 13, no. 2, pp. 101-106, 1992.
37. I. T. Demchenko, A. E. Boso, A. R. Whorton, and C. A. Piantadosi, "Nitric oxide production is enhanced in rat brain before oxygen-induced convulsions, " Brain Research, vol. 917, no. 2, pp. 253-261, 2001.
38. G. M. Rubanyi and P. M. Vanhoutte, "Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor, " American Journal of Physiology, vol. 250, no. 5, part 2, pp. H822-H827, 1986.
39. M. D. Faiman, R. J. Nolan, and F. W. Oehme, "Effect of disulfiram on oxygen toxicity in Beagle dogs, " Aerospace Medicine, vol. 45, no. 1, pp. 29-32, 1974.
40. T. D. Oury, Y.-S. Ho, C. A. Piantadosi, and J. D. Crapo, "Extracellular superoxide dismutase, nitric oxide, and central nervous system O2 toxicity, " Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 20, pp. 9715-9719, 1992.
41. T. Yusa, J. D. Crapo, and B. A. Freeman, "Liposome-mediated augmentation of brain SOD and catalase inhibits CNS O2 toxicity, " Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, vol. 57, no. 6, pp. 1674-1681, 1984.
42. J. Zhang and C. A. Piantadosi, "Prevention of H2O2 generation by monoamine oxidase protects against CNS O2 toxicity, " Journal of Applied Physiology, vol. 71, no. 3, pp. 1057-1061, 1991.
43. S. Oter, A. Korkmaz, T. Topal et al., "Correlation between hyperbaric oxygenexposure pressures andoxidative parameters in rat lung, brain, and erythrocytes, " Clinical Biochemistry, vol. 38, no. 8, pp. 706-711, 2005.
44. A. Korkmaz, S. Oter, S. Sadir et al., "Exposure time related oxidative action of hyperbaric oxygen in rat brain, " Neurochemical Research, vol. 33, no. 1, pp. 160-166, 2008.
45. T. Matsunami, Y. Sato, T. Sato, S. Ariga, T. Shimomura, and M. Yukawa, "Oxidative stress and gene expression of antioxidant enzymes in the streptozotocin-induced diabetic rats under hyperbaric oxygen exposure, " International Journal of Clinical and Experimental Pathology, vol. 3, no. 2, pp. 177-188, 2010.
46. J. F. Bowyer, K. J. Hopkins, R. Jakab, and S. A. Ferguson, "Lephedrine-induced neurodegeneration in the parietal cortex and thalamus of the rat is dependent on hyperthermia and can be altered by the process of in vivo brain microdialysis, " Toxicology Letters, vol. 125, no. 1-3, pp. 151-166, 2001.
47. S.-Y. Yu and C. Chen, "Effect of Chinese medicine compound on frontal lobe structure of ephedrine addiction mice, " Journalof Northwest Normal University (Natural Science), no. 2, pp. 84-89, 2013.
48. Y. Wang, C.-Y. Li, S.-Y. Yu et al., "Effects on the structure of cerebral temporal lobe cortex and capability of learning and memory of filial mice after administration of heroin and ephedrine, " Acta Anatomica Sinica, vol. 40, no. 5, pp. 724-731, 2009.
49. S.-C. Ho, T.-H. Tsai, P.-J. Tsai, and C.-C. Lin, "Protective capacities of certain spices against peroxynitrite-mediated biomolecular damage, " Food and Chemical Toxicology, vol. 46, no. 3, pp. 920-928, 2008.
50. P. J. Tsai, T. H. Tsai, C. H. Yu, and S. C. Ho, "Evaluation ofNOsuppressing activity of several Mediterranean culinary spices, " Food and Chemical Toxicology, vol. 45, no. 3, pp. 440-447, 2007.
51. J.-C. Liao, J.-S. Deng, C.-S. Chiu et al., "Anti-inflammatory activities of Cinnamomum cassia constituents in vitro and in vivo, " Evidence-Based Complementary andAlternativeMedicine, vol. 2012, Article ID429320, 12 pages, 2012.
52. H. S. Youn, J. K. Lee, Y. J. Choi et al., "Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization, " Biochemical Pharmacology, vol. 75, no. 2, pp. 494-502, 2008.
53. T. Kamida, E. Abe, T. Abe, H. Ooba, M. Fujiki, and H. Kobayashi, "Edaravone, a free radical scavenger, retards the development of amygdala kindling in rats, " Neuroscience Letters, vol. 461, no. 3, pp. 298-301, 2009.
54. H. Yoshida, H. Yanai, Y. Namiki, K. Fukatsu-Sasaki, N. Furutani, and N. Tada, "Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury, " CNS Drug Reviews, vol. 12, no. 1, pp. 9-20, 2006.
55. J. Wen, K. Watanabe, M. Ma et al., "Edaravone inhibits JNK-c-Jun pathway and restores anti-oxidative defense after ischemiareperfusion injury in aged rats, " Biological and Pharmaceutical Bulletin, vol. 29, no. 4, pp. 713-718, 2006.
56. T. Watanabe, M. Tanaka, K. Watanabe, Y. Takamatsu, and A. Tobe, "Research and development of the free radical scavenger edaravone as a neuroprotectant, " Yakugaku Zasshi, vol. 124, no. 3, pp. 99-111, 2004.
57. Z. Wang, T. Liu, L. Gan et al., "Shikonin protects mouse brain against cerebral ischemia/reperfusion injury through its antioxidant activity, " European Journal of Pharmacology, vol. 643, no. 2-3, pp. 211-217, 2010.
58. J. W. Phillis, L. A. Horrocks, and A. A. Farooqui, "Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: Teir role and involvement in neurological disorders, " Brain Research Reviews, vol. 52, no. 2, pp. 201-243, 2006.
59. H. Nishi, T. Watanabe, H. Sakurai, S. Yuki, and A. Ishibashi, "Effect of MCI-186 on brain edema in rats, " Stroke, vol. 20, no. 9, pp. 1236-1240, 1989.