Maternal cadmium, iron and zinc levels, DNA methylation and birth weight

BMC Pharmacology and Toxicology

Volumn 16, Issue 1, 2015, Pages

  Vidal, Adriana C ^a   Semenova, Viktoriya ^b,c   Darrah, Thomas ^d   Vengosh, Avner ^e   Huang, Zhiqing ^f   King, Katherine ^f,g   Nye, Monica D ^f,h   Fry, Rebecca ⁱ   Skaar, David ^b   Maguire, Rachel ^b   Murtha, Amy ^f   Schildkraut, Joellen ^f   Murphy, Susan ^f   Hoyo, Cathrine ^b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c EAST CAROLINA UNIVERSITY   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e DUKE UNIVERSITY   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^h UNIVERSITY OF NORTH CAROLINA   (United States)

ⁱ University of North Carolina at Chapel Hill   (United States)

Author keywords

Cadmium; Epigenetics; Genomic imprinting; Obesity; Pediatrics; Zinc

Indexed keywords

CADMIUM; IRON; ZINC; FOLIC ACID;

ADULT; AFRICAN AMERICAN; ARTICLE; CAUCASIAN; CESAREAN SECTION; COHORT ANALYSIS; CONTROLLED STUDY; DNA METHYLATION; ETHNICITY; FEMALE; FIRST TRIMESTER PREGNANCY; GENE; GENETIC ASSOCIATION; HEAVY METAL BLOOD LEVEL; HISPANIC; HUMAN; IRON BLOOD LEVEL; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LOW BIRTH WEIGHT; MALE; MEG3 GENE; PEG3 GENE; PLAGL1 GENE; PRENATAL EXPOSURE; PROSPECTIVE STUDY; SMOKING; VAGINAL DELIVERY; ZINC BLOOD LEVEL; ADVERSE EFFECTS; BIRTH WEIGHT; BLOOD; DRUG EFFECTS; DRUG INTERACTION; FETUS BLOOD; GENETICS; INFANT; MATERNAL EXPOSURE; METABOLISM; PREGNANCY; REGULATORY SEQUENCE; YOUNG ADULT;

ADULT; BIRTH WEIGHT; CADMIUM; DNA METHYLATION; DRUG INTERACTIONS; FEMALE; FETAL BLOOD; FOLIC ACID; HUMANS; INFANT; IRON; MALE; MATERNAL EXPOSURE; PREGNANCY; REGULATORY SEQUENCES, NUCLEIC ACID; YOUNG ADULT; ZINC;

EID: 84937030313     PISSN: 20506511     EISSN: 20506511     Source Type: Journal    
DOI: 10.1186/s40360-015-0020-2     Document Type: Article

References (47)

1. Cadmium [ http://toxtown.nlm.nih.gov/text_version/chemicals.php?id=63 ]
2. Registry: http://www.atsdr.cdc.gov/ . 2011.
3. Hou L, Zhang X, Wang D, Baccarelli A. Environmental chemical exposures and human epigenetics. Int J Epidemiol. 2012;41(1):79-105.
4. Menai M, Heude B, Slama R, Forhan A, Sahuquillo J, Charles MA, et al. Association between maternal blood cadmium during pregnancy and birth weight and the risk of fetal growth restriction: the EDEN mother-child cohort study. Reprod Toxicol. 2012;34(4):622-7.
5. Scott ME, Shvetsov YB, Thompson PJ, Hernandez BY, Zhu X, Wilkens LR, et al. Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study. Int J Cancer. 2013;133(5):1187-96.
6. Zinc: Fact Sheet for Health Professionals [http://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/].
7. Matovic V, Buha A, Bulat Z, Dukic-Cosic D. Cadmium toxicity revisited: focus on oxidative stress induction and interactions with zinc and magnesium. Arh Hig Rada Toksikol. 2011;62(1):65-76.
8. Rogalska J, Brzoska MM, Roszczenko A, Moniuszko-Jakoniuk J. Enhanced zinc consumption prevents cadmium-induced alterations in lipid metabolism in male rats. Chem Biol Interact. 2009;177(2):142-52.
9. Takiguchi M, Achanzar WE, Qu W, Li G, Waalkes MP. Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. Exp Cell Res. 2003;286(2):355-65.
10. Reichard JF, Schnekenburger M, Puga A. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochem Biophys Res Commun. 2007;352(1):188-92.
11. Jiang G, Xu L, Song S, Zhu C, Wu Q, Zhang L, et al. Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells. Toxicology. 2008;244(1):49-55.
12. Sanders AP, Smeester L, Rojas D, Debussycher T, Wu MC, Wright FA, et al. Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. Epigenetics. 2014;9(2):212-21.
13. Woodfine K, Huddleston JE, Murrell A. Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue. Epigenetics Chromatin. 2011;4(1):1.
14. Hoyo C, Murphy SK, Jirtle RL. Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies. J Epidemiol Community Health. 2009;63(9):683-4.
15. Hoyo C, Daltveit AK, Iversen E, Benjamin-Neelon SE, Fuemmeler B, Schildkraut J, et al. Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort. Epigenetics. 2014;9(8):1120-30.
16. Liu Y, Murphy SK, Murtha AP, Fuemmeler BF, Schildkraut J, Huang Z, et al. Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements. Epigenetics. 2012;7(7):735-46.
17. Vidal AC, Murphy SK, Murtha AP, Schildkraut JM, Soubry A, Huang Z, et al. Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. Int J Obes (Lond). 2013;37(7):907-13.
18. Murphy SK, Huang Z, Hoyo C. Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues. PLoS One. 2012;7(7), e40924.
19. Nye MD, Hoyo C, Huang Z, Vidal AC, Wang F, Overcash F, et al. Associations between methylation of paternally expressed gene 3 (PEG3), cervical intraepithelial neoplasia and invasive cervical cancer. PLoS One. 2013;8(2), e56325.
20. Darrah TH, Prutsman-Pfeiffer JJ, Poreda RJ, Ellen Campbell M, Hauschka PV, Hannigan RE. Incorporation of excess gadolinium into human bone from medical contrast agents. Metallomics. 2009;1(6):479-88.
21. DeLoid G, Cohen JM, Darrah T, Derk R, Rojanasakul L, Pyrgiotakis G, et al. Estimating the effective density of engineered nanomaterials for in vitro dosimetry. Nat Commun. 2014;5:3514.
22. McLaughlin MP, Darrah TH, Holland PL. Palladium(II) and platinum(II) bind strongly to an engineered blue copper protein. Inorg Chem. 2011;50(22):11294-6.
23. Sprauten M, Darrah TH, Peterson DR, Campbell ME, Hannigan RE, Cvancarova M, et al. Impact of long-term serum platinum concentrations on neuro- and ototoxicity in Cisplatin-treated survivors of testicular cancer. J Clin Oncol. 2012;30(3):300-7.
24. Reeves PG, Chaney RL. Marginal nutritional status of zinc, iron, and calcium increases cadmium retention in the duodenum and other organs of rats fed rice-based diets. Environ Res. 2004;96(3):311-22.
25. Brzoska MM, Moniuszko-Jakoniuk J. Interactions between cadmium and zinc in the organism. Food Chem Toxicol. 2001;39(10):967-80.
26. Piyathilake CJ, Robinson CB, Cornwell P. A practical approach to red blood cell folate analysis. Anal Chem Insights. 2007;2:107-10.
27. Li L, Keverne EB, Aparicio SA, Ishino F, Barton SC, Surani MA. Regulation of maternal behavior and offspring growth by paternally expressed Peg3. Science. 1999;284(5412):330-3.
28. Chiavegatto S, Sauce B, Ambar G, Cheverud JM, Peripato AC. Hypothalamic expression of Peg3 gene is associated with maternal care differences between SM/J and LG/J mouse strains. Brain Behav. 2012;2(4):365-76.
29. Deng Y, Wu X. Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. Proc Natl Acad Sci U S A. 2000;97(22):12050-5.
30. Johnson MD, Wu X, Aithmitti N, Morrison RS. Peg3/Pw1 is a mediator between p53 and Bax in DNA damage-induced neuronal death. J Biol Chem. 2002;277(25):23000-7.
31. Arita A, Shamy MY, Chervona Y, Clancy HA, Sun H, Hall MN, et al. The effect of exposure to carcinogenic metals on histone tail modifications and gene expression in human subjects. J Trace Elem Med Biol. 2012;26(2-3):174-8.
32. Hossain MB, Vahter M, Concha G, Broberg K. Low-level environmental cadmium exposure is associated with DNA hypomethylation in Argentinean women. Environ Health Perspect. 2012;120(6):879-84.
33. Joubert BR, Haberg SE, Nilsen RM, Wang X, Vollset SE, Murphy SK, et al. 450 K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ Health Perspect. 2012;120(10):1425-31.
34. Murphy SK, Adigun A, Huang Z, Overcash F, Wang F, Jirtle RL, et al. Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke. Gene. 2012;494(1):36-43.
35. Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC. Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, lead and mercury. Genes (Basel). 2014;5(2):477-96.
36. Kippler M, Engstrom K, Mlakar SJ, Bottai M, Ahmed S, Hossain MB, et al. Sex-specific effects of early life cadmium exposure on DNA methylation and implications for birth weight. Epigenetics. 2013;8(5):494-503.
37. Kippler M, Tofail F, Hamadani JD, Gardner RM, Grantham-McGregor SM, Bottai M, et al. Early-life cadmium exposure and child development in 5-year-old girls and boys: a cohort study in rural Bangladesh. Environ Health Perspect. 2012;120(10):1462-8.
38. Akesson A, Berglund M, Schutz A, Bjellerup P, Bremme K, Vahter M. Cadmium exposure in pregnancy and lactation in relation to iron status. Am J Public Health. 2002;92(2):284-7.
39. Maret W, Sandstead HH. Possible roles of zinc nutriture in the fetal origins of disease. Exp Gerontol. 2008;43(5):378-81.
40. Min KS, Iwata N, Tetsutikawahara N, Onosaka S, Tanaka K. Effect of hemolytic and iron-deficiency anemia on intestinal absorption and tissue accumulation of cadmium. Toxicol Lett. 2008;179(1):48-52.
41. Flanagan PR, McLellan JS, Haist J, Cherian G, Chamberlain MJ, Valberg LS. Increased dietary cadmium absorption in mice and human subjects with iron deficiency. Gastroenterology. 1978;74(5 Pt 1):841-6.
42. Yang QY, Liang JF, Rogers CJ, Zhao JX, Zhu MJ, Du M. Maternal obesity induces epigenetic modifications to facilitate Zfp423 expression and enhance adipogenic differentiation in fetal mice. Diabetes. 2013;62(11):3727-35.
43. Fatemi M, Hermann A, Pradhan S, Jeltsch A. The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA. J Mol Biol. 2001;309(5):1189-99.
44. Somoza JR, Skene RJ, Katz BA, Mol C, Ho JD, Jennings AJ, et al. Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases. Structure. 2004;12(7):1325-34.
45. Luedi PP, Dietrich FS, Weidman JR, Bosko JM, Jirtle RL, Hartemink AJ. Computational and experimental identification of novel human imprinted genes. Genome Res. 2007;17(12):1723-30.
46. Liu Y, Hoyo C, Murphy S, Huang Z, Overcash F, Thompson J, et al. DNA methylation at imprint regulatory regions in preterm birth and infection. Am J Obstet Gynecol. 2013;208(5):e391-7. 395.
47. Kippler M1, Tofail F, Gardner R, Rahman A, Hamadani JD, Bottai M, et al. Maternal cadmium exposure during pregnancy and size at birth: a prospective cohort study. Environ Health Perspect. 2012;120(2):284-9.