-
1
-
-
0029860206
-
A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all three ligands
-
Woodcock JM, Bagley CJ, Zacharakis B, Lopez AF. A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all three ligands. J Biol Chem. 1996; 271: 25999-26006
-
(1996)
J Biol Chem
, vol.271
, pp. 25999-26006
-
-
Woodcock, J.M.1
Bagley, C.J.2
Zacharakis, B.3
Lopez, A.F.4
-
2
-
-
0022468416
-
Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice
-
Metcalf D, Begley CG, Johnson GR, Nicola NA, Lopez AF, Williamson DJ. Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice. Blood. 1986; 68: 46-57
-
(1986)
Blood
, vol.68
, pp. 46-57
-
-
Metcalf, D.1
Begley, C.G.2
Johnson, G.R.3
Nicola, N.A.4
Lopez, A.F.5
Williamson, D.J.6
-
3
-
-
84904460162
-
CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies
-
Testa U, Pelosi E, Frankel A. CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies. Biomark Res. 2014; 2: 4
-
(2014)
Biomark Res
, vol.2
, pp. 4
-
-
Testa, U.1
Pelosi, E.2
Frankel, A.3
-
4
-
-
0033815950
-
The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells
-
Jordan CT, Upchurch D, Szilvassy SJ, Guzman ML, Howard DS, Pettigrew AL, et al. The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells. Leukemia. 2000; 14: 1777-1784
-
(2000)
Leukemia
, vol.14
, pp. 1777-1784
-
-
Jordan, C.T.1
Upchurch, D.2
Szilvassy, S.J.3
Guzman, M.L.4
Howard, D.S.5
Pettigrew, A.L.6
-
5
-
-
30644481023
-
Detection of molecular targets on the surface of CD34+/cd38- stem cells in various myeloid malignancies
-
Florian S, Sonneck K, Hauswirth AW, Krauth MT, Schernthaner GH, Sperr WR, et al. Detection of molecular targets on the surface of CD34+/CD38- stem cells in various myeloid malignancies. Leuk Lymphoma. 2006; 47: 207-222
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 207-222
-
-
Florian, S.1
Sonneck, K.2
Hauswirth, A.W.3
Krauth, M.T.4
Schernthaner, G.H.5
Sperr, W.R.6
-
6
-
-
84907597109
-
SL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemia
-
Frolova O, Benito J, Brooks C, Wang RY, Korchin B, Rowinsky EK, et al. SL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemia. Br J Haematol. 2014; 166: 862-874
-
(2014)
Br J Haematol
, vol.166
, pp. 862-874
-
-
Frolova, O.1
Benito, J.2
Brooks, C.3
Wang, R.Y.4
Korchin, B.5
Rowinsky, E.K.6
-
7
-
-
84932085600
-
A phase 1 study of the safety, pharmacokinetics, and anti-leukemic activity of the anti-CD123 monoclonal antibody, CSL360, in relapsed, refractory or high-risk acute myeloid leukemia (AML
-
e-pub ahead of print 20 November. 2014
-
He SZ, Busfield S, Ritchie DS, Hertzberg MS, Durrant S, Lewis ID, et al. A phase 1 study of the safety, pharmacokinetics, and anti-leukemic activity of the anti-CD123 monoclonal antibody, CSL360, in relapsed, refractory or high-risk acute myeloid leukemia (AML). Leuk Lymphoma. 2014; e-pub ahead of print 20 November. 2014; doi:10.3109/10428194.2014.956316
-
(2014)
Leuk Lymphoma
-
-
He, S.Z.1
Busfield, S.2
Ritchie, D.S.3
Hertzberg, M.S.4
Durrant, S.5
Lewis, I.D.6
-
8
-
-
84904505489
-
Activity and tolerability of sl-401, a targeted therapy directed to the interleukin-3 receptor on cancer stem cells and tumor bulk, as a single agent in patients with advanced hematologic malignancies
-
Frankel AE, Konopleva M, Hogge D, Rizzieri D, Brooks C, Cirrito T, et al. Activity and tolerability of SL-401, a targeted therapy directed to the interleukin-3 receptor on cancer stem cells and tumor bulk, as a single agent in patients with advanced hematologic malignancies. J Clin Oncol. 2013; 31: 15
-
(2013)
J Clin Oncol
, vol.31
, pp. 15
-
-
Frankel, A.E.1
Konopleva, M.2
Hogge, D.3
Rizzieri, D.4
Brooks, C.5
Cirrito, T.6
-
9
-
-
84904465235
-
Activity of sl-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients
-
Frankel AE, Woo JH, Ahn C, Pemmaraju N, Medeiros BC, Carraway HE, et al. Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients. Blood. 2014; 124: 385-392
-
(2014)
Blood
, vol.124
, pp. 385-392
-
-
Frankel, A.E.1
Woo, J.H.2
Ahn, C.3
Pemmaraju, N.4
Medeiros, B.C.5
Carraway, H.E.6
-
10
-
-
0025204729
-
Failure to detect il-3-binding sites on human mast cells
-
Valent P, Besemer J, Sillaber C, Butterfield JH, Eher R, Majdic O, et al. Failure to detect IL-3-binding sites on human mast cells. J Immunol. 1990; 145: 3432-3437
-
(1990)
J Immunol
, vol.145
, pp. 3432-3437
-
-
Valent, P.1
Besemer, J.2
Sillaber, C.3
Butterfield, J.H.4
Eher, R.5
Majdic, O.6
-
11
-
-
77949268924
-
Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes
-
Teodosio C, Garcia-Montero AC, Jara-Acevedo M, Sanchez-Munoz L, Alvarez-Twose I, Nunez R, et al. Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes. J Allergy Clin Immunol. 2010; 125: 719-726
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 719-726
-
-
Teodosio, C.1
Garcia-Montero, A.C.2
Jara-Acevedo, M.3
Sanchez-Munoz, L.4
Alvarez-Twose, I.5
Nunez, R.6
-
12
-
-
84955079518
-
Cd30/cd123 expression in systemic mastocytosis does not correlate with aggressive disease
-
Moonim MT, Kossier T, van Der Walt J, Wilkins B, Harrison CN, Radia DH. CD30/CD123 expression in systemic mastocytosis does not correlate with aggressive disease. Blood. 2012; 120: 21
-
(2012)
Blood
, vol.120
, pp. 21
-
-
Moonim, M.T.1
Kossier, T.2
Van Der Walt, J.3
Wilkins, B.4
Harrison, C.N.5
Radia, D.H.6
-
13
-
-
61549132662
-
Mastocytosis
-
Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al. (eds 4th edn. International Agency for Research and Cancer (IARC): Lyon
-
Horny HP, Metcalfe DD, Bennett JM, Bain BJ, Akin C, Escribano L, et al. Mastocytosis. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al. (eds) WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues, 4th edn. International Agency for Research and Cancer (IARC): Lyon, 2008; pp 54-63
-
(2008)
WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues
, pp. 54-63
-
-
Horny, H.P.1
Metcalfe, D.D.2
Bennett, J.M.3
Bain, B.J.4
Akin, C.5
Escribano, L.6
-
14
-
-
84879372052
-
Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and management
-
Pardanani A. Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and management. Am J Hematol. 2013; 88: 612-624
-
(2013)
Am J Hematol
, vol.88
, pp. 612-624
-
-
Pardanani, A.1
-
15
-
-
85015854839
-
Durable responses and improved quality of life with midostaurin (PKC412) in advanced systemic mastocytosis (SM): Updated stage 1 results of the global D2201 trial
-
Gotlib J, Kluin-Nelemans HC, George TI, Akin C, Sotlar K, Hermine O, et al. Durable responses and improved quality of life with midostaurin (PKC412) in advanced systemic mastocytosis (SM): updated stage 1 results of the Global D2201 trial. Blood. 2013; 122: 21
-
(2013)
Blood
, vol.122
, pp. 21
-
-
Gotlib, J.1
Kluin-Nelemans, H.C.2
George, T.I.3
Akin, C.4
Sotlar, K.5
Hermine, O.6
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