메뉴 건너뛰기




Volumn 36, Issue 4, 2015, Pages 1644-1658

The Effects of Dasatinib in Experimental Acute Respiratory Distress Syndrome Depend on Dose and Etiology

Author keywords

Acute respiratory distress syndrome; Cytokines; Dasatinib; Histology; Lung mechanics; Toll like receptor 4

Indexed keywords

DASATINIB; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 10; INTERLEUKIN 6; TOLL LIKE RECEPTOR 4; VASCULOTROPIN; PROTEIN KINASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN A;

EID: 84936966602     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430325     Document Type: Article
Times cited : (26)

References (39)
  • 3
    • 84855877337 scopus 로고    scopus 로고
    • Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury
    • Duan Y, Learoyd J, Meliton AY, Leff AR, Zhu X: Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury. Respiratory Research 2012;13:4.
    • (2012) Respiratory Research , vol.13 , pp. 4
    • Duan, Y.1    Learoyd, J.2    Meliton, A.Y.3    Leff, A.R.4    Zhu, X.5
  • 4
    • 84879086917 scopus 로고    scopus 로고
    • Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery
    • Kim IK, Rhee CK, Yeo CD, Kang HH, Lee DG, Lee SH, Kim JM: Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery. Critical Care 2013;17:R114.
    • (2013) Critical Care , vol.17 , pp. R114
    • Kim, I.K.1    Rhee, C.K.2    Yeo, C.D.3    Kang, H.H.4    Lee, D.G.5    Lee, S.H.6    Kim, J.M.7
  • 5
  • 6
    • 79958724618 scopus 로고    scopus 로고
    • Protein tyrosine kinases in neutrophil activation and recruitment
    • Zarbock A, Ley K: Protein tyrosine kinases in neutrophil activation and recruitment. Arch Biochem Biophys 2011;510:112-119.
    • (2011) Arch Biochem Biophys , vol.510 , pp. 112-119
    • Zarbock, A.1    Ley, K.2
  • 7
    • 34247470836 scopus 로고    scopus 로고
    • Second generation inhibi-tors of BCRABL for the treatment of imatinib-resistant chronic myeloid leukaemia
    • Weisberg E, Manley PW, Cowan-Jacob SW, Hochhaus A, Griffin JD: Second generation inhibi-tors of BCRABL for the treatment of imatinib-resistant chronic myeloid leukaemia. Nat Rev Cancer 2007;7:345-356.
    • (2007) Nat Rev Cancer , vol.7 , pp. 345-356
    • Weisberg, E.1    Manley, P.W.2    Cowan-Jacob, S.W.3    Hochhaus, A.4    Griffin, J.D.5
  • 9
    • 84899073185 scopus 로고    scopus 로고
    • Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma
    • Lowe DB, Bose A, Taylor JL, Tawbi H, Lin Y, Kirkwood JM, Storkus WJ: Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma. Oncoimmunology 2014;3:e27589.
    • (2014) Oncoimmunology , vol.3 , pp. e27589
    • Lowe, D.B.1    Bose, A.2    Taylor, J.L.3    Tawbi, H.4    Lin, Y.5    Kirkwood, J.M.6    Storkus, W.J.7
  • 10
    • 84899107609 scopus 로고    scopus 로고
    • Effectiveness of dasatinib in accelerated-phase chronic myeloid leukemia with p190 BCR-ABL1 and a second Philadelphia chromosome
    • Rabenau KE, Dolan M, Yohe S, Ustun C: Effectiveness of dasatinib in accelerated-phase chronic myeloid leukemia with p190 BCR-ABL1 and a second Philadelphia chromosome. Cancer Genet 2014;207:109-110.
    • (2014) Cancer Genet , vol.207 , pp. 109-110
    • Rabenau, K.E.1    Dolan, M.2    Yohe, S.3    Ustun, C.4
  • 11
    • 84861519200 scopus 로고    scopus 로고
    • Dasatinib inhibits proinflammatory functions of mature human neutrophils
    • Futosi K, Németh T, Pick R, Vántus T, Walzog B, Mócsai A: Dasatinib inhibits proinflammatory functions of mature human neutrophils. Blood 2012;119:4981-4991.
    • (2012) Blood , vol.119 , pp. 4981-4991
    • Futosi, K.1    Németh, T.2    Pick, R.3    Vántus, T.4    Walzog, B.5    Mócsai, A.6
  • 12
    • 70449411507 scopus 로고    scopus 로고
    • Dasatinib inhibits the secretion of TNF-alpha following TLR stimulation in vitro and in vivo
    • Fraser CK, Lousberg EL, Kumar R, Hughes TP, Diener KR, Hayball JD: Dasatinib inhibits the secretion of TNF-alpha following TLR stimulation in vitro and in vivo. Exp Hematol 2009;37:1435-1444.
    • (2009) Exp Hematol , vol.37 , pp. 1435-1444
    • Fraser, C.K.1    Lousberg, E.L.2    Kumar, R.3    Hughes, T.P.4    Diener, K.R.5    Hayball, J.D.6
  • 13
    • 20044363664 scopus 로고    scopus 로고
    • Src and Syk kinases: Key regulators of phagocytic cell activation
    • Berton G, Mócsai A, Lowell CA: Src and Syk kinases: key regulators of phagocytic cell activation. Trends Immunol 2005;26:208-214.
    • (2005) Trends Immunol , vol.26 , pp. 208-214
    • Berton, G.1    Mócsai, A.2    Lowell, C.A.3
  • 14
    • 84907211081 scopus 로고    scopus 로고
    • The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without direct role in leukocyte recruitment
    • Kovács M, Németh T, Jakus Z, Sitary C, Simon E, Futosi K, Botz B, Helyes Z, Lowell CA, Mócsai A: The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without direct role in leukocyte recruitment. J Exp Med 2014;11:1993-2011.
    • (2014) J Exp Med , vol.11 , pp. 1993-2011
    • Kovács, M.1    Németh, T.2    Jakus, Z.3    Sitary, C.4    Simon, E.5    Futosi, K.6    Botz, B.7    Helyes, Z.8    Lowell, C.A.9    Mócsai, A.10
  • 17
    • 38149131234 scopus 로고    scopus 로고
    • Pulmonary and extrapulmonary acute respiratory distress syndrome: Myth or reality
    • Rocco PRM, Pelosi P: Pulmonary and extrapulmonary acute respiratory distress syndrome: myth or reality Curr Opin Crit Care 2008;14:50-55.
    • (2008) Curr Opin Crit Care , vol.14 , pp. 50-55
    • Rocco, P.R.M.1    Pelosi, P.2
  • 21
    • 0022256369 scopus 로고
    • Analysis of the behavior of the respiratory system with constant inspiratory flow
    • Bates JH, Rossi A, Milic-Emili J: Analysis of the behavior of the respiratory system with constant inspiratory flow. J Appl Physiol (1985) 1985;58:1840-1848.
    • (1985) J Appl Physiol (1985) , vol.58 , pp. 1840-1848
    • Bates, J.H.1    Rossi, A.2    Milic-Emili, J.3
  • 25
    • 79952179437 scopus 로고    scopus 로고
    • Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib
    • Haouala A, Widmer N, Duchosal MA, Montemurro M, Buclin T, Decosterd LA: Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib. Blood 2011;117:e75-e87.
    • (2011) Blood , vol.117 , pp. e75-e87
    • Haouala, A.1    Widmer, N.2    Duchosal, M.A.3    Montemurro, M.4    Buclin, T.5    Decosterd, L.A.6
  • 26
    • 84881146816 scopus 로고    scopus 로고
    • The relative efficacy of imatinib, dasatinib and nilotinib for newly diagnosed chronic myeloid leukemia: A systematic review and network metaanalysis
    • Mealing S, Barcena L, Hawkins N, Clark J, Eaton V, Hirji I, Davis C: The relative efficacy of imatinib, dasatinib and nilotinib for newly diagnosed chronic myeloid leukemia: A systematic review and network metaanalysis. Exp Hematol Oncol 2013;19:5.
    • (2013) Exp Hematol Oncol , vol.19 , pp. 5
    • Mealing, S.1    Barcena, L.2    Hawkins, N.3    Clark, J.4    Eaton, V.5    Hirji, I.6    Davis, C.7
  • 27
    • 84920577517 scopus 로고    scopus 로고
    • The clinically-approved drugs Dasatinib and Bosutinib induce antiinflammatory macrophages by inhibiting the Salt-Inducible Kinases
    • Ozanne J, Prescott AR, Clark K: The clinically-approved drugs Dasatinib and Bosutinib induce antiinflammatory macrophages by inhibiting the Salt-Inducible Kinases. Biochem J 2015;465:271-279.
    • (2015) Biochem J , vol.465 , pp. 271-279
    • Ozanne, J.1    Prescott, A.R.2    Clark, K.3
  • 28
    • 79955610378 scopus 로고    scopus 로고
    • Nilotinib ameliorates lipopolysaccharide-induced acute lung injury in rats
    • El-Agamy DS: Nilotinib ameliorates lipopolysaccharide-induced acute lung injury in rats. Toxicol Appl Pharmacol 2011;253:153-160.
    • (2011) Toxicol Appl Pharmacol , vol.253 , pp. 153-160
    • El-Agamy, D.S.1
  • 29
    • 38449099025 scopus 로고    scopus 로고
    • Src tyrosine kinases mediate activations of NF-B and integrin signal during lipopolysaccharide-induced acute lung injury
    • Lee HS, Moon C, Lee HW, Park EM, Cho MS, Kang JL: Src tyrosine kinases mediate activations of NF-B and integrin signal during lipopolysaccharide-induced acute lung injury. J Immunol 2007;179:7001-7011.
    • (2007) J Immunol , vol.179 , pp. 7001-7011
    • Lee, H.S.1    Moon, C.2    Lee, H.W.3    Park, E.M.4    Cho, M.S.5    Kang, J.L.6
  • 30
    • 84879086917 scopus 로고    scopus 로고
    • Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery
    • Kim IK, Rhee CK, Yeo CD, Kang HH, Lee DG, Lee SH, Kim JW: Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery. Crit Care 2013;17:R114.
    • (2013) Crit Care , vol.17 , pp. R114
    • Kim, I.K.1    Rhee, C.K.2    Yeo, C.D.3    Kang, H.H.4    Lee, D.G.5    Lee, S.H.6    Kim, J.W.7
  • 31
    • 84893045171 scopus 로고    scopus 로고
    • Protective effects of bone marrow-derived endothelial progenitor cells and houttuynia cordata in lipopolysaccharide-induced acute lung injury in rats
    • Cai DS, Zhou H, Liu WW, Pei L: Protective effects of bone marrow-derived endothelial progenitor cells and Houttuynia cordata in lipopolysaccharide-induced acute lung injury in rats. Cell Physiol Biochem 2013;32:1577-1586.
    • (2013) Cell Physiol Biochem , vol.32 , pp. 1577-1586
    • Cai, D.S.1    Zhou, H.2    Liu, W.W.3    Pei, L.4
  • 32
    • 0034746518 scopus 로고    scopus 로고
    • Nebulized prostacyclin (PGI2) in acute respiratory distress syndrome: Impact of primary (pulmonary injury) and secondary (extrapulmonary injury) disease on gas exchange response
    • Domenighetti G, Stricker H, Waldispuehl B: Nebulized prostacyclin (PGI2) in acute respiratory distress syndrome: impact of primary (pulmonary injury) and secondary (extrapulmonary injury) disease on gas exchange response. Crit Care Med 2001;29:57-62.
    • (2001) Crit Care Med , vol.29 , pp. 57-62
    • Domenighetti, G.1    Stricker, H.2    Waldispuehl, B.3
  • 34
    • 37249048453 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics and in vitro metabolism of dasatinib (BMS-354825): A potent oral multi-targeted kinase inhibitor against SRC and BCR-ABL
    • Kamath AV, Wang J, Lee FY, Marathe PH: Preclinical pharmacokinetics and in vitro metabolism of dasatinib (BMS-354825): A potent oral multi-targeted kinase inhibitor against SRC and BCR-ABL. Cancer Chemother Pharmacol 2008;61:365-376.
    • (2008) Cancer Chemother Pharmacol , vol.61 , pp. 365-376
    • Kamath, A.V.1    Wang, J.2    Lee, F.Y.3    Marathe, P.H.4
  • 36
    • 84880555809 scopus 로고    scopus 로고
    • The role of TLR4 in the pathogenesis of indirect acute lung injury
    • Hu R, Xu H, Jiang H, Zhang Y, Sun Y: The role of TLR4 in the pathogenesis of indirect acute lung injury. Front Biosci 2013;18:1244-1255.
    • (2013) Front Biosci , vol.18 , pp. 1244-1255
    • Hu, R.1    Xu, H.2    Jiang, H.3    Zhang, Y.4    Sun, Y.5
  • 37
    • 84879655800 scopus 로고    scopus 로고
    • TLR4 as receptor for HMGB1-mediated acute lung injury after liver ischemia/reperfusion injury
    • Yang Z, Deng Y, Su D, Tian J, Gao Y, He Z, Wang X: TLR4 as receptor for HMGB1-mediated acute lung injury after liver ischemia/reperfusion injury. Lab Invest 2013;93:792-800.
    • (2013) Lab Invest , vol.93 , pp. 792-800
    • Yang, Z.1    Deng, Y.2    Su, D.3    Tian, J.4    Gao, Y.5    He, Z.6    Wang, X.7
  • 38
    • 80053172099 scopus 로고    scopus 로고
    • TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways
    • Perros F, Lambrecht BN, Hammad H: TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways. Respir Res 12: 125, 2011.
    • (2011) Respir Res , vol.12 , pp. 125
    • Perros, F.1    Lambrecht, B.N.2    Hammad, H.3
  • 39
    • 0036841093 scopus 로고    scopus 로고
    • Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and acute respiratory distress syndrome
    • Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, Zimmerman GA, Matthay MA, Ware LB: Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and acute respiratory distress syndrome. Am J Pathol 2002;161:1783-86.
    • (2002) Am J Pathol , vol.161 , pp. 1783-1786
    • Albertine, K.H.1    Soulier, M.F.2    Wang, Z.3    Ishizaka, A.4    Hashimoto, S.5    Zimmerman, G.A.6    Matthay, M.A.7    Ware, L.B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.