Proteomic Analysis of Human Pluripotent Stem Cell-Derived, Fetal, and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and Maturation

Circulation: Cardiovascular Genetics

Volumn 8, Issue 3, 2015, Pages 427-436

  Poon, Ellen ^a   Keung, Wendy ^a   Liang, Yimin ^a   Ramalingam, Rajkumar ^a   Yan, Bin ^a   Zhang, Shaohong ^a   Chopra, Anant ^a,b   Moore, Jennifer ^a   Herren, Anthony ^a   Lieu, Deborah K ^a   Wong, Hau San ^a   Weng, Zhihui ^a   Wong, On Tik ^a   Lam, Yun Wah ^a   Tomaselli, Gordon F ^a   Chen, Christopher ^a,b   Boheler, Kenneth R ^a   Li, Ronald A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

embryonic stem cells; metabolism; PGC1alpha protein; PPARalpha; proteomics; thyroid stimulating hormone

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIRINIXIC ACID; THYROID HORMONE; LIOTHYRONINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRIMIDINE DERIVATIVE;

ADULT; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; FETUS; GENE EXPRESSION PROFILING; HEART MUSCLE CELL; HEART MUSCLE METABOLISM; HEART VENTRICLE WALL; HUMAN; MITOCHONDRIAL MEMBRANE POTENTIAL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CLUSTER ANALYSIS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; HEART MUSCLE; HEART VENTRICLE; HUMAN EMBRYONIC STEM CELL; LIPID PEROXIDATION; METABOLISM; MUSCLE CONTRACTION;

CELL DIFFERENTIATION; CELLS, CULTURED; CLUSTER ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FETUS; GENE EXPRESSION REGULATION; HEART VENTRICLES; HUMAN EMBRYONIC STEM CELLS; HUMANS; LIPID PEROXIDATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MUSCLE CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; PPAR ALPHA; PROTEOMICS; PYRIMIDINES; TRIIODOTHYRONINE;

EID: 84936948039     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.114.000918     Document Type: Article

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