-
1
-
-
0035012803
-
The epidemiology of rheumatoid arthritis
-
Gabriel SE. The epidemiology of rheumatoid arthritis. Rheum Dis Clin North Am 2001;27(2):269-81
-
(2001)
Rheum Dis Clin North A.m
, vol.27
, Issue.2
, pp. 269-281
-
-
Gabriel, S.E.1
-
2
-
-
78149492075
-
State-of-The-art: Rheumatoid arthritis [published erratum appears in Ann Rheum Dis 2011;70:399
-
McInnes IB, O'Dell JR. State-of-The-art: rheumatoid arthritis [published erratum appears in Ann Rheum Dis 2011;70:399]. Ann Rheum Dis 2010;69:1898-906
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1898-1906
-
-
McInnes, I.B.1
O'dell, J.R.2
-
3
-
-
84859832981
-
Update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis
-
Singh JA, Furst DE, Bharat A, et al. Update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken) 2012;64:625-39
-
(2012)
Arthritis Care Res (Hoboken)
, vol.64
, pp. 625-639
-
-
Singh, J.A.1
Furst, D.E.2
Bharat, A.3
-
4
-
-
84893721202
-
Efficacy of biological diseasemodifying antirheumatic drugs: A systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis
-
Nam JL, Ramiro S, Gaujoux-Viala C, et al. Efficacy of biological diseasemodifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 2014;73(3):516-28
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.3
, pp. 516-528
-
-
Nam, J.L.1
Ramiro, S.2
Gaujoux-Viala, C.3
-
5
-
-
0035010959
-
Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts
-
Panayi GS, Corrigall V, Pitzalis C. Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts. Rheum Dis Clin North Am 2001;27:317-34
-
(2001)
Rheum Dis Clin North A.m
, vol.27
, pp. 317-334
-
-
Panayi, G.S.1
Corrigall, V.2
Pitzalis, C.3
-
6
-
-
0035207357
-
The autoimmune pathogenesis of rheumatoid arthritis: Role of autoreactive T cells and new immunotherapies
-
VanderBorght A, Geusens P, Raus J, et al. The autoimmune pathogenesis of rheumatoid arthritis: role of autoreactive T cells and new immunotherapies. Semin Arthritis Rheum 2001;31:160-75
-
(2001)
Semin Arthritis Rheum
, vol.31
, pp. 160-175
-
-
Vanderborght, A.1
Geusens, P.2
Raus, J.3
-
7
-
-
0035932519
-
Cytokine pathways and joint inflammation in rheumatoid arthritis
-
Choy EH, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001;344:907-16
-
(2001)
N Engl J Med
, vol.344
, pp. 907-916
-
-
Choy, E.H.1
Panayi, G.S.2
-
8
-
-
0036024679
-
The molecular mechanism of osteoclastogenesis in rheumatoid arthritis
-
Udagawa N, Kotake S, Kamatani N, et al. The molecular mechanism of osteoclastogenesis in rheumatoid arthritis. Arthritis Res 2002;4:281-9
-
(2002)
Arthritis Res
, vol.4
, pp. 281-289
-
-
Udagawa, N.1
Kotake, S.2
Kamatani, N.3
-
9
-
-
0036214017
-
The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
-
Carreno BM, Collins M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol 2002;20:29-53
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 29-53
-
-
Carreno, B.M.1
Collins, M.2
-
10
-
-
0036072614
-
Targeting T cell costimulation in autoimmune disease
-
Stuart RW, Racke MK. Targeting T cell costimulation in autoimmune disease. Exp Opin Ther Targets 2002;6:275-89
-
(2002)
Exp Opin Ther Targets
, vol.6
, pp. 275-289
-
-
Stuart, R.W.1
Racke, M.K.2
-
11
-
-
0025830902
-
CTLA-4 is a second receptor for the B cell activation antigen B7
-
Linsley PS, Brady W, Urnes M, et al. CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med 1991;174:561-9
-
(1991)
J Exp Med
, vol.174
, pp. 561-569
-
-
Linsley, P.S.1
Brady, W.2
Urnes, M.3
-
12
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
Walunas TL, Lenschow DJ, Bakker CY, et al. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994;1:405-13
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
-
13
-
-
0029914089
-
Covalent dimerization of CD28/CTLA- 4 and oligomerization of CD80/ CD86 regulate T cell costimulatory interactions
-
Greene JL, Leytze GM, Emswiler J, et al. Covalent dimerization of CD28/CTLA- 4 and oligomerization of CD80/ CD86 regulate T cell costimulatory interactions. J Biol Chem 1996;271:26762-71
-
(1996)
J Biol Chem
, vol.271
, pp. 26762-26771
-
-
Greene, J.L.1
Leytze, G.M.2
Emswiler, J.3
-
14
-
-
77956682118
-
Subcutaneous administration of abatacept in patients with rheumatoid arthritis: Pharmacokinetics, safety and immunogenicity
-
Corbo M, Valencia X, Raymond R, et al. Subcutaneous administration of abatacept in patients with rheumatoid arthritis: pharmacokinetics, safety and immunogenicity. Ann Rheum Dis 2009;68:S574
-
(2009)
Ann Rheum Dis
, vol.68
, pp. S574
-
-
Corbo, M.1
Valencia, X.2
Raymond, R.3
-
16
-
-
80053493531
-
Subcutaneous abatacept versus intravenous abatacept: A phase IIIb noninferiority study in patients with an inadequate response to methotrexate
-
Genovese MC, Covarrubias A, Leon G, et al. Subcutaneous abatacept versus intravenous abatacept: a phase IIIb noninferiority study in patients with an inadequate response to methotrexate. Arthritis Rheum 2011;63:2854-64
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2854-2864
-
-
Genovese, M.C.1
Covarrubias, A.2
Leon, G.3
-
17
-
-
84878118308
-
Subcutaneous abatacept: Long-term data from the ACQUIRE trial
-
Genovese M, Pacheco-Tena C, Covarrubias A, et al. Subcutaneous abatacept: long-term data from the ACQUIRE trial. Arthritis Rheum 2012;64(10 Suppl):S201
-
(2012)
Arthritis Rheum
, vol.64
, Issue.10
, pp. S201
-
-
Genovese, M.1
Pacheco-Tena, C.2
Covarrubias, A.3
-
18
-
-
82955189834
-
Evaluation of abatacept administered subcutaneously in adults with active rheumatoid arthritis: Impact of withdrawal and reintroduction on immunogenicity, efficacy and safety (phase IIIb ALLOW study)
-
Kaine J, Gladstein G, Strusberg I, et al. Evaluation of abatacept administered subcutaneously in adults with active rheumatoid arthritis: impact of withdrawal and reintroduction on immunogenicity, efficacy and safety (phase IIIb ALLOW study). Ann Rheum Dis 2012;71:38-44
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 38-44
-
-
Kaine, J.1
Gladstein, G.2
Strusberg, I.3
-
19
-
-
84878129657
-
Subcutaneous abatacept is effective and well tolerated, with low immunogenicity following temporary withdrawal and reintroduction in the ALLOW LTE
-
Kaine J, Gladstein G, Strusberg I, et al. Subcutaneous abatacept is effective and well tolerated, with low immunogenicity following temporary withdrawal and reintroduction in the ALLOW LTE. Arthritis Rheum 2011;63:S853
-
(2011)
Arthritis Rheum
, vol.63
, pp. S853
-
-
Kaine, J.1
Gladstein, G.2
Strusberg, I.3
-
20
-
-
77957787973
-
Abatacept demonstrates consistent safety and sustained improvements in effi cacy through 4 years of open-label treatment in patients with an inadequate response to anti-TNF therapy
-
Genovese MC, Schiff M, Luggen ME, et al. Abatacept demonstrates consistent safety and sustained improvements in effi cacy through 4 years of open-label treatment in patients with an inadequate response to anti-TNF therapy. Arthritis Rheum 2009;60(Suppl 10):1689
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1689
-
-
Genovese, M.C.1
Schiff, M.2
Luggen, M.E.3
-
21
-
-
41849120516
-
Effi cacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-tumour necrosis factor therapy
-
Genovese MC, Schiff M, Luggen M, et al. Effi cacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-tumour necrosis factor therapy. Ann Rheum Dis 2008;67:547-54
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 547-554
-
-
Genovese, M.C.1
Schiff, M.2
Luggen, M.3
-
22
-
-
42449098374
-
Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate
-
Kremer JM, Genant HK, Moreland LW, et al. Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate. Arthritis Rheum 2008;58:953-63
-
(2008)
Arthritis Rheum
, vol.58
, pp. 953-963
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
-
23
-
-
77953122238
-
Abatacept demonstrates consistent safety and sustained improvements in effi cacy through 5 years of treatment in biologicnaïve patients with R.A
-
Kremer JM, Russell AS, Emery P, et al. Abatacept demonstrates consistent safety and sustained improvements in effi cacy through 5 years of treatment in biologicnaïve patients with RA. Ann Rheum Dis 2009;68(Suppl 3):FRI0263
-
(2009)
Ann Rheum Dis
, vol.68
, pp. FRI0263
-
-
Kremer, J.M.1
Russell, A.S.2
Emery, P.3
-
24
-
-
84860916327
-
Abatacept in subjects who switch from intravenous to subcutaneous therapy: Results from the phase IIIb ATTUNE study
-
Keystone EC, Kremer JM, Russell A, et al. Abatacept in subjects who switch from intravenous to subcutaneous therapy: results from the phase IIIb ATTUNE study. Ann Rheum Dis 2012;71:857-61
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 857-861
-
-
Keystone, E.C.1
Kremer, J.M.2
Russell, A.3
-
25
-
-
84871813585
-
Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: Findings of a phase IIIb, multinational, prospective, randomized study
-
Weinblatt M, Schiff M, Valente R, et al. Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: findings of a phase IIIb, multinational, prospective, randomized study. Arthritis Rheum 2012;65:28-38
-
(2012)
Arthritis Rheum
, vol.65
, pp. 28-38
-
-
Weinblatt, M.1
Schiff, M.2
Valente, R.3
-
26
-
-
84889641417
-
Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: Two-year efficacy and safety findings from AMPLE trial
-
Schiff M, Weinblatt ME, Valente R, et al. Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: two-year efficacy and safety findings from AMPLE trial. Ann Rheum Dis 2014;73(1):86-94
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.1
, pp. 86-94
-
-
Schiff, M.1
Weinblatt, M.E.2
Valente, R.3
-
27
-
-
84918571233
-
Evaluation drug-frr remission with abatacept in early rheumatoid arthritis; Study of 24 months from AVERT trial phase IIIb
-
Emery P, Burmetster GR, Bykerk VP, et al. Evaluation drug-frr remission with abatacept in early rheumatoid arthritis; study of 24 months from AVERT trial phase IIIb. Ann Rheum Dis 2015;74:19-26
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 19-26
-
-
Emery, P.1
Burmetster, G.R.2
Bykerk, V.P.3
-
28
-
-
77949442819
-
Impact of T-cell costimulation modulation in patients with undifferentiated inflammatory arthritis or very early rheumatoid arthritis: A clinical and imaging study of abatacept (the ADJUST trial)
-
Emery P, Durez P, Dougados M, et al. Impact of T-cell costimulation modulation in patients with undifferentiated inflammatory arthritis or very early rheumatoid arthritis: a clinical and imaging study of abatacept (the ADJUST trial). Ann Rheum Dis 2010;69:510-16
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 510-516
-
-
Emery, P.1
Durez, P.2
Dougados, M.3
-
29
-
-
65349176911
-
Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors
-
Westhovens R, Robles M, Ximenes AC, et al. Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors. Ann Rheum Dis 2009;68:1870-7
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1870-1877
-
-
Westhovens, R.1
Robles, M.2
Ximenes, A.C.3
-
30
-
-
84860915495
-
Safety of subcutaneous abatacept in patients with rheumatoid arthritis (RA): Integrated analysis of five clinical trials up to 4.5 years
-
Alten R, Kaine J, Keystone EC, et al. Safety of subcutaneous abatacept in patients with rheumatoid arthritis (RA): Integrated analysis of five clinical trials up to 4.5 years. Ann Rheum Dis 2011;70(Suppl 3):617
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 617
-
-
Alten, R.1
Kaine, J.2
Keystone, E.C.3
-
31
-
-
84863910858
-
Safety profile of subcutaneous abatacept focusing on clinically relevant events in patients with rheumatoid arthritis (RA) and up to 4.5 years of exposure
-
Alten R, Kaine J, Keystone EC, et al. Safety profile of subcutaneous abatacept focusing on clinically relevant events in patients with rheumatoid arthritis (RA) and up to 4.5 years of exposure. Arthritis Rheum 2011;63:S150
-
(2011)
Arthritis Rheum
, vol.63
, pp. S150
-
-
Alten, R.1
Kaine, J.2
Keystone, E.C.3
-
32
-
-
79953018875
-
Adverse effects of biologics: A network meta-analysis and Cochrane overview
-
Singh JA, Wells GA, Christensen R, et al. Adverse effects of biologics: a network meta-analysis and Cochrane overview. Cochrane Database Syst Rev 2011(2):1-60
-
(2011)
Cochrane Database Syst Rev
, Issue.2
, pp. 1-60
-
-
Singh, J.A.1
Wells, G.A.2
Christensen, R.3
-
33
-
-
84876701598
-
Immunogenicity, safety and efficacy of subcutaneous abatacept with or without MTX in patients with rheumatoid arthritis: The Phase III ACCOMPANY study
-
Nash P, Nayiager S, Genovese M, et al. Immunogenicity, safety and efficacy of subcutaneous abatacept with or without MTX in patients with rheumatoid arthritis: the Phase III ACCOMPANY study. Arthritis Care Res (Hoboken) 2013;65(5):718-28
-
(2013)
Arthritis Care Res (Hoboken)
, vol.65
, Issue.5
, pp. 718-728
-
-
Nash, P.1
Nayiager, S.2
Genovese, M.3
-
34
-
-
72249096209
-
Malignancies in the rheumatoid arthritis abatacept clinical development programme: An epidemiological assessment
-
Simon TA, Smitten AL, Franklin J, et al. Malignancies in the rheumatoid arthritis abatacept clinical development programme: an epidemiological assessment. Ann Rheum Dis 2009;68:1819-26
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1819-1826
-
-
Simon, T.A.1
Smitten, A.L.2
Franklin, J.3
-
35
-
-
67650137185
-
Dealing with immunogenicity of biologicals: Assessment and clinical relevance
-
Wolbink GJ, Aarden LA, Dijkmans BA. Dealing with immunogenicity of biologicals: assessment and clinical relevance. Curr Opin Rheumatol 2009;21:211-15
-
(2009)
Curr Opin Rheumatol
, vol.21
, pp. 211-215
-
-
Wolbink, G.J.1
Aarden, L.A.2
Dijkmans, B.A.3
-
36
-
-
36848999429
-
Evaluation of immunogenicity of the T cell costimulation modulator abatacept in patients treated for rheumatoid arthritis
-
Haggerty HG, Abbott MA, Reilly TP, et al. Evaluation of immunogenicity of the T cell costimulation modulator abatacept in patients treated for rheumatoid arthritis. J Rheumatol 2007;34:2365-73
-
(2007)
J Rheumatol
, vol.34
, pp. 2365-2373
-
-
Haggerty, H.G.1
Abbott, M.A.2
Reilly, T.P.3
-
37
-
-
80052505451
-
Differential effect of drug interference in immunogenicity assays
-
Hart MH, de Vrieze H, Wouters D, et al. Differential effect of drug interference in immunogenicity assays. J Immunol Methods 2011;372:196-203
-
(2011)
J Immunol Methods
, vol.372
, pp. 196-203
-
-
Hart, M.H.1
De Vrieze, H.2
Wouters, D.3
-
38
-
-
84878141214
-
Efficacy, safety and pharmacokinetics of subcutaneous abatacept in patients with rheumatoid arthritis, with or without an intravenous (IV) loading dose
-
Nash P, Ludivico C, Delaet I, et al. Efficacy, safety and pharmacokinetics of subcutaneous abatacept in patients with rheumatoid arthritis, with or without an intravenous (IV) loading dose. Arthritis Rheum 2011;63(Suppl 10):S151
-
(2011)
Arthritis Rheum
, vol.63
, pp. S151
-
-
Nash, P.1
Ludivico, C.2
Delaet, I.3
-
39
-
-
84878150937
-
Weekly subcutaneous abata cept confers comparable onset of treatment response and magnitude of efficacy improvement over 6 months when administered with or without an intravenous abatacept loading dose
-
Schiff M, Alten R, Weinblatt M, et al. Weekly subcutaneous abata cept confers comparable onset of treatment response and magnitude of efficacy improvement over 6 months when administered with or without an intravenous abatacept loading dose. Arthritis Rheum 2012;64(Suppl 10):S1076
-
(2012)
Arthritis Rheum
, vol.64
, pp. S1076
-
-
Schiff, M.1
Alten, R.2
Weinblatt, M.3
|