DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 27, 2015, Pages 8385-8390

  Cox, Nehemiah ^a   Pilling, Darrell ^a   Gomer, Richard H ^a   Ravetch, Jeffrey V ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

DC SIGN; Fibrosis; IL 10; Pentraxin; Serum amyloid P

Indexed keywords

AMINOTHIAZOLE; BLEOMYCIN; C REACTIVE PROTEIN; CD209 ANTIGEN; FC RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; MEMBRANE PROTEIN; PROTEIN SIGN R1; SERUM AMYLOID P; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 2-AMINOTHIAZOLE; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; DC-SPECIFIC ICAM-3 GRABBING NONINTEGRIN; LECTIN; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EPITHELIUM CELL; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INNATE IMMUNITY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM; ANIMAL; C57BL MOUSE; CELL CULTURE; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; METABOLISM; PATHOLOGY; PULMONARY FIBROSIS; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; BLOTTING, WESTERN; C-REACTIVE PROTEIN; CELL ADHESION MOLECULES; CELLS, CULTURED; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-10; LECTINS, C-TYPE; LUNG; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NEUTROPHILS; PROTEIN BINDING; PULMONARY FIBROSIS; RECEPTORS, CELL SURFACE; RECEPTORS, IGG; SERUM AMYLOID P-COMPONENT; THIAZOLES;

EID: 84936871416     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1500956112     Document Type: Article

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