Inhibition of Experimental autoimmune encephalomyelitis in human C-reactive protein transgenic mice is FcγRIIB dependent

Autoimmune Diseases

Volumn 1, Issue 1, 2011, Pages

  Hu, Xian Zhen ^a   Wright, Tyler T ^a   Jones, Nicholas R ^a   Ramos, Theresa N ^b   Skibinski, Gregory A ^a   McCrory, Mark A ^a   Barnum, Scott R ^b   Szalai, Alexander J ^a  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CD16 ANTIGEN; FC RECEPTOR; FC RECEPTOR I; FC RECEPTOR IIB; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG TREATMENT FAILURE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; WILD TYPE;

EID: 84877683214     PISSN: None     EISSN: 20900430     Source Type: Journal    
DOI: 10.4061/2011/484936     Document Type: Article

References (25)

1. Gabay C., Kushner I., Acute-phase proteins and other systemic responses to inflammation New England Journal of Medicine 1999 340 6 448 454 (Pubitemid 29084777)
2. Szalai A. J., The antimicrobial activity of C-reactive protein Microbes and Infection 2002 4 2 201 205 (Pubitemid 34183495)
3. Bisoendial R. J., Boekholdt S. M., Vergeer M., Stroes E. S. G., Kastelein J. J. P., C-reactive protein is a mediator of cardiovascular disease European Heart Journal 2010 31 17 2087 2095
4. Szalai A. J., Weaver C. T., McCrory M. A., Van Ginkel F. W., Reiman R. M., Kearney J. F., Marion T. N., Volanakis J. E., Delayed lupus onset in (NZB NZW)F1 mice expressing a human C-reactive protein transgene Arthritis and Rheumatism 2003 48 6 1602 1611 (Pubitemid 36682368)
5. Rodriguez W., Mold C., Marnell L. L., Hutt J., Silverman G. J., Tran D., Du Clos T. W., Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein Arthritis and Rheumatism 2006 54 1 325 335 (Pubitemid 43122216)
6. Szalai A. J., Nataf S., Hu X.-Z., Barnum S. R., Experimental allergic encephalomyelitis is inhibited in transgenic mice expressing human C-reactive protein Journal of Immunology 2002 168 11 5792 5797 (Pubitemid 34556165)
7. Marnell L. L., Mold C., Volzer M. A., Burlingame R. W., Du Clos T. W., C-reactive protein binds to FcγRI in transfected COS cells Journal of Immunology 1995 155 4 2185 2193
8. Stein M.-P., Mold C., Du Clos T. W., C-reactive protein binding to murine leukocytes requires Fc receptors Journal of Immunology 2000 164 3 1514 1520 (Pubitemid 30067268)
9. Mold C., Gresham H. D., Du Clos T. W., Serum amyloid P component and C-reactive protein mediate phagocytosis through murine Fc Rs Journal of Immunology 2001 166 2 1200 1205 (Pubitemid 32060280)
10. Lu J., Marnell L. L., Marjon K. D., Mold C., Du Clos T. W., Sun P. D., Structural recognition and functional activation of Fc R by innate pentraxins Nature 2008 456 7224 989 992
11. Kleinau S., Martinsson P., Heyman B., Induction and suppression of collagen-induced arthritis is dependent on distinct Fc receptors Journal of Experimental Medicine 2000 191 9 1611 1616 (Pubitemid 30257357)
12. Barnes N., Gavin A. L., Tan P. S., Mottram P., Koentgen F., Hogarth P. M., FcγRI-deficient mice show multiple alterations to inflammatory and immune responses Immunity 2002 16 3 379 389 (Pubitemid 34260916)
13. Smith K. G. C., Clatworthy M. R., FcγRIIB in autoimmunity and infection: evolutionary and therapeutic implications Nature Reviews Immunology 2010 10 5 328 343
14. Szalai A. J., Barnum S. R., Fc receptors and the common -chain in experimental autoimmune encephalomyelitis Journal of Neuroscience Research 2004 75 5 597 602 (Pubitemid 38280699)
15. Iruretagoyena M. I., Riedel C. A., Leiva E. D., Gutiérrez M. A., Jacbobelli S. H., Kalergis A. M., Activating and inhibitory Fc receptors can differentially modulate T cell-mediated autoimmunity European Journal of Immunology 2008 38 8 2241 2250
16. Ciliberto G., Arcone R., Wagner E. F., Rther U., Inducible and tissue-specific expression of human C-reactive protein in transgenic mice EMBO Journal 1987 6 13 4017 4022
17. Szalai A. J., McCrory M. A., Varied biologic functions of C-reactive protein: lessons learned from transgenic mice Immunologic Research 2002 26 13 279 287 (Pubitemid 35177504)
18. Takai T., Ono M., Hikida M., Ohmori H., Ravetch J. V., Augmented humoral and anaphylactic responses in FcγRII-deficient mice Nature 1996 379 6563 346 349 (Pubitemid 26033077)
19. Hazenbos W. L. W., Gessner J. E., Hofhuis F. M. A., Kuipers H., Meyer D., Heijnen I. A. F. M., Schmidt R. E., Sandor M., Capel P. J. A., Daron M., Van De Winkel J. G. J., Verbeek J. S., Impaired IgG-dependent anaphylaxis and Arthus reaction in FcγRIII (CD16) deficient mice Immunity 1996 5 2 181 188 (Pubitemid 26301094)
20. Rodriguez W., Mold C., Kataranovski M., Hutt J. A., Marnell L. L., Verbeek J. S., Du Clos T. W., C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fc receptors Journal of Immunology 2007 178 1 530 538 (Pubitemid 46033637)
21. Xing D., Hage F. G., Chen Y.-F., McCrory M. A., Feng W., Skibinski G. A., Majid-Hassan E., Oparil S., Szalai A. J., Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (FcγRI)-dependent American Journal of Pathology 2008 172 1 22 30 (Pubitemid 351186364)
22. Nimmerjahn F., Bruhns P., Horiuchi K., Ravetch J. V., FcγRIV: a novel FcR with distinct IgG subclass specificity Immunity 2005 23 1 41 51 (Pubitemid 41019656)
23. Nimmerjahn F., Ravetch J. V., Fc receptors: old friends and new family members Immunity 2006 24 1 19 28 (Pubitemid 43077197)
24. Szalai A. J., Hu X., Raman C., Barnum S. R., Requirement of the Fc receptor common -chain for T cell-mediated promotion of murine experimental autoimmune encephalomyelitis European Journal of Immunology 2005 35 12 3487 3492 (Pubitemid 43025530)
25. Zhang R., Becnel L., Li M., Chen C., Yao Q., C-reactive protein impairs human CD14+ monocyte-derived dendritic cell differentiation, maturation and function European Journal of Immunology 2006 36 11 2993 3006 (Pubitemid 44782573)