The impact of preoperative statin therapy on open and endovascular abdominal aortic aneurysm repair outcomes

Vascular

Volumn 23, Issue 4, 2015, Pages 344-349

  Galiñanes, Edgar Luis ^a   Reynolds, Shaun ^a   Dombrovskiy, Viktor Y ^b   Vogel, Todd R ^a  

^a University of Missouri   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Abdominal aortic aneurysm; outcomes; statin

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ABDOMINAL AORTA ANEURYSM; ADULT; AGED; AORTIC EMBOLISM; ARTICLE; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; DIGESTIVE SYSTEM DISEASE; ENDOVASCULAR ABDOMINAL AORTIC ANEURYSM REPAIR; ENDOVASCULAR ANEURYSM REPAIR; FEMALE; HEART ARREST; HEART INFARCTION; HUMAN; ICD-9-CM; KAPLAN MEIER METHOD; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; POSTOPERATIVE COMPLICATION; PREOPERATIVE CARE; PRIORITY JOURNAL; SURVIVAL; THROMBOSIS; TREATMENT OUTCOME; ADVERSE EFFECTS; AORTIC ANEURYSM, ABDOMINAL; CHI SQUARE DISTRIBUTION; COMPARATIVE STUDY; ENDOVASCULAR SURGERY; HOSPITAL MORTALITY; MEDICARE; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODEL; PROTECTION; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; STATISTICAL MODEL; TIME FACTOR; UNITED STATES; VASCULAR SURGERY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AORTIC ANEURYSM, ABDOMINAL; CHI-SQUARE DISTRIBUTION; ENDOVASCULAR PROCEDURES; FEMALE; HOSPITAL MORTALITY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; MALE; MEDICARE PART D; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODELS; PROTECTIVE FACTORS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES; VASCULAR SURGICAL PROCEDURES;

EID: 84936866023     PISSN: 17085381     EISSN: 1708539X     Source Type: Journal    
DOI: 10.1177/1708538114552837     Document Type: Article

References (16)

1. R.S.RosensonC.C.Tangney. Antiatherothrombotic properties of statins: implications for cardiovascular event reduction. JAMA1998; 279: 1643–1650.
2. P.LibbyM.Aikawa. Mechanisms of plaque stabilization with statins. Am J Cardiol2003; 91: 4B–8B.
3. K.I.ParaskevasA.S.WierzbickiD.P.Mikhailidis. Statins and noncardiac vascular disease. Curr Opin Cardiol2012; 27: 392–397.
4. T.R.VogelV.Y.DombrovskiyE.L.Galinanes. Preoperative statins and limb salvage after lower extremity revascularization in the medicare population. Circul Cardiovasc Interven2013; 6: 694–700.
5. M.RauxF.CochennecJ.P.Becquemin. Statin therapy is associated with aneurysm sac regression after endovascular aortic repair. J Vasc Surg2012; 55: 1587–1592.
6. O.SchoutenE.BoersmaS.E.Hoeks. Fluvastatin and perioperative events in patients undergoing vascular surgery. N Engl J Med2009; 361: 980–989.
7. M.D.KertaiE.BoersmaC.M.Westerhout. Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery. Am J Med2004; 116: 96–103.
8. C.P.TwineI.M.Williams. Systematic review and meta-analysis of the effects of statin therapy on abdominal aortic aneurysms. Br J Surg2011; 98: 346–353.
9. J.L.de BruinA.F.BaasM.W.Heymans. Statin therapy is associated with improved survival after endovascular and open aneurysm repair. J Vasc Surg2014; 59: 39–44.
10. M.M.McNallyS.C.AgleF.M.Parker. Preoperative statin therapy is associated with improved outcomes and resource utilization in patients undergoing aortic aneurysm repair. J Vasc Surg2010; 51: 1390–1396.
11. R.D.SandersA.NicholsonS.R.Lewis. Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery. Cochr Database Syst Rev2013; 7: CD009971–CD009971.
12. F.VioliC.CalvieriD.Ferro. Statins as antithrombotic drugs. Circulation2013; 127: 251–257.
13. S.KinlayG.G.SchwartzA.G.Olsson. Myocardial ischemia reduction with aggressive cholesterol lowering Study I. High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the miracl study. Circulation2003; 108: 1560–1566.
14. J.PleinerG.SchallerF.Mittermayer. Simvastatin prevents vascular hyporeactivity during inflammation. Circulation2004; 110: 3349–3354.
15. S.SubherwalM.R.PatelL.Kober. Missed opportunities: despite improvement in use of cardioprotective medications among patients with lower-extremity peripheral artery disease, underuse remains. Circulation2012; 126: 1345–1354.
16. M.S.ConteD.F.BandykA.W.Clowes. Risk factors, medical therapies and perioperative events in limb salvage surgery: Observations from the prevent iii multicenter trial. J Vasc Surg2005; 42: 456–464. discussion 464–455.